LUPRON Reviews (LEUPROLIDE ACETATE)

Average Rating: 2.7 (853 Ratings)

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 DRUGS USED IN DISORDERS OF GROWTH HORMO HORMONAL BIOLOGICAL RESPONSE MODIFIERS

 Type: Rx Drug

  

LUPRON  (LEUPROLIDE ACETATE):  Leuprolide is used to stop early puberty (precocious puberty) in children. It helps to delay sexual development (such as growth of the breasts/testicles) and the start of menstrual periods. It also helps slow down early bone growth to increase the likelihood of reaching normal adult height. Leuprolide works by decreasing the amount of sex hormones that a child's body makes (estrogen in girls, testosterone in boys).   FDA Approval Date: 1985-04-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LUPRONCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Endometriosis Headaches, nausea, memory loss, weight gain, weight loss, depression, anxiety, suicidal thoughts, uncontrollable anger, mood swings, hot flashes, Insomnia, Night Sweats, facial hair growth, acne, deepening voice, Body aches, No sexual desire, Lots of swinging emotions. I had gotten a rare side effect with "Break through bleeding" so I had to take another medicine for that for a month.I had taken Lupron two other times in my past. Now I remember why I didn not want to take it again. Its a nightmare. It's been out of my system now for two months & I'm still suffering with some of its side effects. I dont feel like the same person anymore, but I've been trying to get a hold of myself & tell myself its all in my head before these side effects destroy my personal life. Lupron DID help me, but no promises the endometriosis will not come back. I wish I never took it to begin with. F 21 3 months
1X AN
4/4/2013
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 3  endomitriosis Hot flashes, night sweats, severe mood swings, depression, vaginal dryness, lowering of my voice I'm not having period cramps because, hey-no periods, but I seem to get "phantom cramps" at the time I would normally menstrate. I started this therepy because I was told it was my only chance for ever being able to have children, but sometimes I wonder if rug-ratsare worth all of this. I was briefly suicidal at the beging of my treatment and severely depressed. For these symptoms THERE IS add-back therapy and it has helped a ton with my mood swings and even with my libidl and vaginal dryness. I still get moody and it has put a lot of tension into my relationship with my fiance. If he were any less understanding the wedding would have been called off a month ago.I'm hoping, especially after reading all the negative comments listed here, that the medication will deliver what was promised: being able to walk down the beach without cringing in pain and, hopefully, a family. F 21 2 months
8/29/2006
 3  Endometriosis/Cysts weight loss, depression, hot flashes, dizziness, night sweats, COMPLETE LOSS OF SEX DRIVE The first month, this drug seems like a miracle to me, I wasn't in pain for a whole month!! I usually had two or more episodes of cysts bursting and HORRIBLE pelvic pains that would last for weeks- to where I would have to take vicodin every time I ate because just the movement of my bowels would start heavy cramps. I was happy with not being in pain, and barely had any side effects for a month... now I have a lot, and they seem to be getting worse. I have ZERO sex drive, even kissing my boyfriend of a year is a turn off. I don't want him to hold me, or touch me, and I am just grossed out by the idea of sex. I used to LOVVVEEE making love, so it's very depressing. I have been crying to him about it constantly. I also wake up in sweats, and either feel FREEZING COLD or have a hot flash every day. I am dizzy, and I have very little appetite. I have also LOST 13 lbs, which has brought me down to 96 lbs!!! I have always had mild depression, but it's been RIDICULOUS lately how down I am. I am pretty sure I am going to reject taking this shot again. I'd rather have a laproscopic surgery or something, I can't take what this is doing to my life. It works GREAT for not having pain, but I personally can't deal with the side effects. If you think you can, then you will be happy with how it helps your pain. I do appreciate not being in any pain anymore... I'm just too young not to have a sex drive and I fear it's ruining my relationship. F 21 2 months
1X day
5/13/2010
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 3  Endometriosis Memory loss, joint pain, hot flashes, headaches, nausea, dry skin I had two three-month shots of Lupron at age 21 after having laparascopic surgery for endo in hopes of improving my chances of fertility and for better periods. Five years later, I'm still on BC but my periods are very light and regular. I still have problems with memory loss, speech difficulty, and joint pain - and I wonder (and will always wonder) how much can be attributed to Lupron. If I could go back in time, I wouldn't do it. F 21 6 months
1X O
3/10/2011
 3  Endo Hot flashes, headaches, dizziness, fatigue, loss of sex drive, and much much more. I am 3 months in. I still get my period each month-- like 3 times a month. I guess my cramps are gone but goodness I want these side effects to stop. F 21 3 months
9/14/2007
 3  Anomiosis and Stage 5 endo I gained weight, always tired, horrible horrible mood swings, anxiety, depression, always crying, bruise easily, acne wich I have nver had in my life. I am 21 years old I started the lupron injections five months ago because I have anomiosis amd endometriosis.I have been sick since i was eleven. I have had five surgeries nothing has helped so lupron was the last thing to try. I am on a low dose of it. I absolutly hate it. I thougt i was getting better but this month which is my 5th month is bad Im in costant pain. Im very emotional. I just feel so slow and depressed. Im only on it another month Im just wondering what happens when I go off. F 21 5 months
10/9/2009
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 2  Endo/Extreme Bleeding hot flashes, night sweats, weight gain I cant stand this I thought everything was great and it was until my second shot now I have put on about 5 lbs and cant slee due to night sweats I am sweating like a pig I feel grose alot of the time. I am supposed to be on this for 6 months but I think this is it. I ant more children but not if I have to go through this F 21 2 months
9/24/2008
 2  endometreosis Hot flashes, insomnia, mood swings, fatigue, night sweats, vaginal dryness, loss of sex drive, depression I decided to take Lupron because of the advice my doctor gave me. I had a laparoscopy in March and the endometreosis was removed but the pain was not relieved. The Lupron did help my back pain, but the additional side effects were not worth it. I feel like I have a totally different personality now and am constantly tired. I can not sleep more than 2-3 hours a night when I don't take a sleeping pill. I only received one injection and declined receiving a second dose. My back pain is slowly coming back, but unfortuanately none of the side effects from Luron are going away. My body still hasn't resumed a normal menstrual cycle. DO NOT TAKE THIS DRUG UNLESS YOU HAVE NO OTHER OPTIONS! F 21 4 months
10/7/2008
 2  stage 3 endo Night sweats,trouble remembering things,low sex drive,hormonal F 21 3 months
2/20/2012
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 1  endometreosis I still had alot of pain, severe hot flashes, moodswings, weightgain, and joint paint. I am now 25 and still have all these symptoms and still no period 4 years later. I am tired, sore, cranky moody not, like myself. My doctor still can't explain why my cycle never returned. Bigest mistake F 21 3 months
1/31/2012
 1  Endometriosis mood swings, hot flashes, headaches while on it, gained 80lbs After being on this drug I developed Fibromyalgia, TMJ, chronic headaches, among other issues plus my Endometriosis did NOT go away. I had NONE of these issues before being on Lupron(except endo). NO ONE SHOULD BE ON THIS DRUG in general, but especially for after a 12month period, the FDA says that is enough for a lifetime because it is a reproductive toxin. F 21 6 months
1X M
9/14/2010
 1  Endo, Chronic Cysts, back & pelvic Weight Gain, Depression, Loss of Libido, Muscle Loss and Pain, Pelvic & Back Pain, Hot Flashes, Hip, Legs and Joint Pain. Loss of Sleep and Night Sweats, Fatigue, Swelling and Water Retention, Break through Bleeding w/Ovarian Cysts. Early signs of Osteoporosis. If you r going to do this, make sure you have a support system, my fiance had to endure ALOT, but he pulled me through! Lupron wasn't for me, I started the shot when is was 18 yrs old, and for the next yr & 1/2 I felt like a 85 yr old woman. I was very healthy and athletic before the shot, days after the side effects started and cont. till 6 months AFTER I was off the shot. I also went through a withdrawl period! I had to start going to physical therapists 3 times a week for pelivc, hip and lower back pain 2mnths after 1st shot. I was diagnosed with PMDD and early signs of osteoporosis. I have been off for 6mnths and have had 2 period, and they where the most painful and debilitating experience ever. I lost one good job because of this, I am doing all I can not to lose another. Dr. wanted to do this to get me off all the narcotic meds, and I had to up them b/c of this. My only question is where do I go from here, I have had surgery, done the shot, done other replacement hormones, I F 21 18 months
6/12/2007
 1  Precocious puberty I was given this horrible chemotherapy drug as a child to treat precocious puberty. It's only been the past few years that I have connected my health problems to this horrible poison drug. I have constant bone pain, osteoarthritis in all my joints, disc problems, fibromyalgia, chronic fatigue, and brain fog. I feel exhausted and like death all the time. I wish my parents knew that this would ruin my health long term, I would have much rather just gone through puberty earlier than become crippled and ill with these horrible symptoms daily. 21 4 months
1X day
1/5/2022
 5  endomitriosis I was diagnosed with endomitriosis at 18. I had been taking bc pills to keep the pain and blood down. I was spotting badly and so we decided to try lupron to calm things down. So far I have had almost no side affects other than some minor bouts of deppression. No heat, pain, fatigue and no periods. I would definitely suggest the taking-back or whatever they call it with the estrogen. I feel better than I did taking the birth control. While this may not be for everyone, I see no reason for giving it a try. You never know until you try. F 20 2 months
6/3/2008
 5  Endo Hot flashes, Insomnia, Fatigue, Mood Swings When I got the Lupron shot, I was not informed of all the side effects. It was not until after I found this website that I learned about how much it would truly effect me. Lupron has changed my everyday life, I have hot flashes, cant sleep AT ALL, I am constantly worn out, and mood swings like I have never experienced before in my life! Even though I have so many things hindering my everyday life, THE PAIN HAS STOPPED! Which makes it all worth it to me. I went to my family doctor and explained I was on the shot and he put me on Cymbalta (which helps a ton!). I would recommend this treatment, just make sure you are prepared to deal with the side effects. F 20 5 months
8/29/2009
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 5  Endometriosis Hot flushes rather have them than the pain of endo only problem I had was as soon as treatment stopped endo came back F 20 6 months
12/27/2011
 4  fibroid I'm in my 20's and have been taking lupron for 5 months, I've put on at least 10lbs, I have no mood swings but the memory loss is insane, maybe I just cant remember the mood swings. I cant remember names of people or things that have taken place and I'm usually quite brilliant. confusion, hot flashes, insomnia, falling asleep randomly, slow mental capabilities, high sugar and overall food cravings. Swollen abdomen. The bleeding has reduced to mere spotting, but it is ever so sporadic. Its better that the alternative F 20 5 months
7/5/2007
 4  fibroid I'm in my 20's and have been taking lupron for 5 months, I've put on at least 10lbs, I have no mood swings but the memory loss is insane, maybe I just cant remember the mood swings. I cant remember names of people or things that have taken place and I'm usually quite brilliant. confusion, hot flashes, insomnia, falling asleep randomly, slow mental capabilities, high sugar and overall food cravings. Swollen abdomen. The bleeding has reduced to mere spotting, but it is ever so sporadic. Its better that the alternative F 20 5 months
7/5/2007
 4  endometriosis Hot flashes, headaches, mood swings The pros definately outweigh the cons. I was a newlywed when I was diagnosed and I had horrible pain with intercourse before I began my injections. A month after I started Lupron I had no pain. The day or so after I get my injection I feel kind of cruddy and get a pretty bad headache. I also have hot flashes everyday and mood swings. All of these side effects are definately worth it. I feel so much better! F 20 5 months
1/8/2009
 4  Endometriosis Hot flashes, real bad muscle aches, nausea, headaches, mood swings, fatigue. I had an ovarian cyst removed in May 2009, when the doctor found some endometriosis. Started having real bad symptoms of the endo in August, got my first Lupron shot at the end of September and I just got my second shot four days ago. I saw my college's health services today because I thought I had the flu, I'm so achy and exhausted, but I don't have a fever or anything so I think they're likely symptoms of the lupron. I am on the pill that came with the shot, take that every morning and I think its better with that because I missed one once and I was MISERABLE. I think I've had "hot flashes", in the sense that I sweat more than usual and sometimes feel very warm, but nothing like older women I know who are actually going through natural menopause. I feel TERRIBLE today, but I guess body aches is better than being doubled over in severe abdominal pain every other day? F 20 1 months
11/3/2009
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