ACTOS Reviews (PIOGLITAZONE HYDROCHLORIDE)

Average Rating: 1.7 (361 Ratings)

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 BLOOD GLUCOSE REGULATORS

 Type: Rx Drug

  

ACTOS  (PIOGLITAZONE HYDROCHLORIDE):  Pioglitazone is a diabetes drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Pioglitazone is used either alone or in combination with other diabetes medications (such as metformin or a sulfonylurea such as glyburide). Talk to your doctor about the risks and benefits of pioglitazone.   FDA Approval Date: 1999-07-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ACTOSCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Type 2 Diabetes I am having a lot of problems with sweating at night(sleeping) and after eating breakfast which I had never noticed when on Metformin alone. No weight gain, but my thirst in the evening is crazy. Too expensive. M 49 6 months
9/21/2009
 1  Type 2 diabetic I'm not sure if the following is from Actos but after reading what other people have written I seem to agree with them on the following side affects...Weight gain that I can't seem to loose. Extreem Fatigue. Swelling of ankles and legs. Very expensive M 66 2 years
9/18/2009
 1  Dr. prescribed My dr. performed a special DNA blood test for Cholesterol and it showed that I might develop Diabetes in the next 10 years, so he tried Metformin, which I didn't like the way it made me feel. He then changed me to Actos which I've taken for more than a year. I ended up in the ER with from an episode of being in a catatonic state for about 2 minutes and found that I had a Hypoglycemia attack. I also had low blood pressure from Lisinopril. The ER dr. said to immediately stop the Lisinopril and I also stopped the Actos. I'm lucky to be alive and I'm going to a new dr. next week. F 63 500 days
9/2/2009
 1  Type II diabetes Initially actos seemed wonderful. Then the weight gain started. I had recently lost 50 lbs and was dismayed to be gaining weight after improving my diet and exercising regularly. I noticed achy muscles and fatigue but attributed it to the weight gain (40lbs in 6 months). with the muscle pain came slight joint pain (ankles/knees some shoulder pain) but recently that has turned severe. It is to the point that just walking is a hardship, exercising is out of the question and getting down on the floor to play with my granddaughter(2) and son(10) is completely out of the question. I have lost coordination sometimes feeling as if I have to actually concentrate on the process of walking as my body won't do it naturally. I am even waking at night in pain. I have an extremely high tolerance for pain and I don't whine about minor aches and pains. My family knows if I am complaining this is something serious. My most recent symptom has been the swelling feet ankles and hands. I have been up 30 mi I am relatively young and have no desire to walk like an ancient old woman.I want my life back. I am seeing the Dr in just a few hours and I won't be taking actos again. This is not the medication for me. My mother, father and brother all take it without the extreme side effects that I have experienced. All have had some weight gain and muscle/joint pain but none to the extreme that walking is a chore and that breathing causes weight gain. As for the people who think the weight gain is from twinkies and stuffing my face let me just say that is not the case. I am eating far better now than I ever have and until the extreme pain was exercising regularly. I am being far more proactive than I was when I lost 50 lbs shortly before starting the actos. I am happy you didn't experience what I and several others have. That means you are lucky not that we are lazy pigs, try a little compassion and understanding. Some day you might need it yourself. F 43 6 months
8/31/2009
 1  Type II Diabetes Weight gain, increased appetite, some tiredness I have only been taking this medication for 2 months, but I am going to stop. My weight has been stable for several years, but I have gained 6 lbs after starting Actos. All I want to do is eat. Yes I am sure the added pounds are from overeating, but my appetite has increased enormously. Came to this site trying to figure out what was going on with my body. After reading the comments, I feel sure it is the Actos. F 55 2 months
8/30/2009
 2  Type II Gained over 50 lbs in less than 8 months. Don't use it. M 48 8 months
8/20/2009
 1  higher than normal insulin levels muscle and joint pain so severe I couldn't get up from a seated position without the aide of someone else. The muscle pain and joint pain came on slowly and after 2 months I was convinced I had some horrible illness. Than I thought calmly and realized this pain started shortly after I started ACTOS. I discontinued taking ACTOS and within the week the pain lessen and after two weeks of not taking ACTOS, the pain was gone completely. My GP was quiet upset that I discontinued ACTOS without telling her. She informed me that there was nothing wrong with ACTOS and the problem with pain in my muscles and joints was all in my head. F 48 60 days
8/20/2009
 1  Type 2 Diabetes Gained over 30 pounds in 5 years, severe swelling in legs, severe leg cramps at night, fatigue,muscle and joint pain. Was taking this with Metformin and Glyburide. Stopped taking Actos and lost the 30 pounds in 90 days. Muscle cramps and swelling went away. Would not recommend this to anyone! M 50 5 years
8/19/2009
 1  Diabetes Bloating, weight gain, leg and muscle cramps, fluid retention, fatigue,joint and chest pain. My doctor added Actos 8 yrs ago to the Metformin I was taking.It improved my A1C but I gained 8 lbs/year & began suffering leg/muscle cramps.My ankles & feet became swollen & joints so sore I could hardly move.On 1200 calorie/day diet & exercise I couldn't lose weight.I became so fatigued & short of breath, I could hardly function.Exercise became harder because of the pain in my legs & joints.I'm 6'6" & always been 250 lbs & now found myself over 300.Those saying it was the "twinkies or stuffing my mouth", I was eating 1200 calories per day & running 2 km.My doctor wanted to "staple" my stomach.After spending a night in hospital where doctors thought I was having a heart attack, I decided it was enough. I'd read about weight gain with Actos & talked my doctor into letting me drop this horrible drug.He doubled my Metformin to 2000mg per day & I stopped taking Actos.Without changing anything in my diet or daily routine, I began losing a pound every 2 days.The first month I lost 15 pounds.My doctor couldn't believe it.It's been 4 months now & I've lost 40 lbs! The loss slowed to 5 lbs a month now, but it took me 8 years to put it on.I wouldn't take this drug for anything in the world.It'll drive you to an early grave.I'm still fatigued & seeing a neurologist for damage caused to my legs & my A1C is higher now at 7.3, but my doctor prefers the weight loss to the lower A1C.By the way, I'm now eating 1 M 49 8 years
8/19/2009
 2  Diabetes II After 3 days of Actos and baby Aspirin together I experienced a TIA-like episode making it difficult for me to communicate temporarily; there was a buzzing sensation, a brief dyslexia and a peculiar depressive period that evening. At my doctor's request I stayed on the drugs. That all passed gradually over the next day, or two. Over the following weeks I developed a slightly bloated and extra-sensitive feeling which was easy to ignore. However, impossible to ignore was ringing in my ears so loud it was keeping me awake. After stopping both drugs at the same time the ringing mostly subsided and the bloated/sensitive feeling was completley gone after another 2 or 3 weeks. Stopping both drugs after 3 weeks to my doctor's dismay, I'm not sure if the Actos helped with blood sugars because it was my first line drug while I was making major diet and excercise changes. Monitoring BGs throughout the day: diet and excercise had the most obvious effect on BG levels, much more obvious than Actos. M 45 3 weeks
8/16/2009
 1  Diabetes II Gained over 20 pounds, swelling in feet and ankles. Lethargy, confusion, sore throat, dizziness. Numbness in my legs, pain in feet, legs and lower back. Stopped taking Actos now for about 2 weeks and it is amazing the energy I have. No aches in the feet, legs or back. Remarkable the way I feel after stopping that medication in just a short period of time. I took it for 18 months. It makes you wonder what the doctors are prescribing, not to mention the fact that my sugar levels were no different than before I took it. F 55 18 months
8/11/2009
 1  Metformin didn't work Swelling of my feet Metformin made me sick, so my doc decided to try Actos. Within three days my feet were so swollen my canvas shoes that it looked like they were two sizes too small. Plus my feet were red. F 52 3 days
8/10/2009
 1  Type 2 I only took this for one month. Three weeks after I started taking it, I started having periods again. Not normal periods, I bleed 6 or 7 days and stop for 2 to 3 days. I haven't taken it for 2 months and still going. I am almost 60 years old. I hate this. Can someone tell me how long will this last? I wish the Dr. had told me this side effect before I started, I would have refused. F 59 30 days
8/6/2009
 4  Type 2 Don't know if it's Actos by it self because my Dr has me on a cocktail of 2000mg metformin,100mg ofJanuvia and 45mg ofActos, but I have developed a thin skin condition where in stead of bruising I bleed under the skin.The Januvia works great as an appetite supressant because I dropped 20lbs after I started taking Januvia. M 60 5 years
8/4/2009
 4  Diabetes 2 Out of the 20 possible side effects listed in the package leaflet from Takeda, Vertigo,Dizziness, and Insomnia bother me the most. I know it that besides taking the Actos I also need to cut down on sweets (cookies) and do some excercise. So wrote the FDA in a 2002 letter. So far, I have managed to stay at A1C of 6.1 +/- 0.1 with 30 mg daily tablet. As a retiree on Medicare Drug Plan D I'll enter the donut hole this month (July). Since Actos price is sky hi in the US I have been ordering it from Canada for the 6 months supply left this year. I have paid $208 for 84 tablets by Takeda, plus S&H and $20 for credit card conversion fee. See www.DoctorSolve.com. I wished that there was a reliable alternative to Actos. Metformin did not help me enough. At age 80 I weigh 230 lbs. It would be nice if I lost 30 lbs. Hey, I go to the gym 3 times a week and take a daily walk of 45 min with the dog. M 80 3 years
8/3/2009
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 1  Type II Diabetes Told I had Diabetes II two months ago. Started out on Metforman, 500 mg, diet control, exercise (a mile a day) but after a few weeks, had to come off because of extreme stomach pain. My numbers did come down. Went off of medication for 10 days and the was put on Actos, 15mg. Within a day or so, I started having tooth pain, hot flashes, extreme hunger, muscle pain, weight gain, dizziness and fatigue. My numbers went up - not down. I feel like a guinea pig. Doctors don't seem to know much about this disease and don't really have time to listen or tell me very much except to shove a new prescryption in front of me to try. I must apparently educate myself on Diabetes 11 and try to help guide my treatment myself. Actos is not going to be a part of it though. Ever feel like the pills they give you are far worse than the disease? F 68 8 days
7/24/2009
 1  Type 2 Diabetes After being on Actos for almost 2 years I had to figure out what was going on with my body and found out it was the Actos I was taking. I have been off Actos for 3 months and am beginning to feel more like my old self. I have more energy, can remember things, swelling is going away, over all body ache is getting better. I am no longer hungry all the time and am sleeping better!!!! Am trying to loose the 25 pound weight gain. I cannot believe this drug caused so much trauma to my body and mind. My doctor saw the change for the better in me today and now believes it was the Actos. I would never recommend it to anyone! F 53
7/23/2009
 1  Diabetes muscle pain; I walked like I was 90. Leg cramps at night. Just a feeling of being exhausted all the time.Gained weight. We will find out this drug has so many side effects; that lawyers will be running ads on T.V wanting you to sue. There will never be a cure for Diabetes because there is to much money in treating it. We have to learn to treat it ourselves.Actoes did lower blood sugar but at what price. F 54 12 months
7/21/2009
 1  Diabetes Type II I have severe muscle cramps in my legs and have gained over 25 pounds since I have been taking this drug. F 64 1 years
7/18/2009
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 1  Type 2 Diabetes Weight gain, leg pain, lethargy, and did not lower blood sugar at all. F 43 14 months
7/17/2009

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