ACTOS Reviews (PIOGLITAZONE HYDROCHLORIDE)

Average Rating: 1.7 (361 Ratings)

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 BLOOD GLUCOSE REGULATORS

 Type: Rx Drug

  

ACTOS  (PIOGLITAZONE HYDROCHLORIDE):  Pioglitazone is a diabetes drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Pioglitazone is used either alone or in combination with other diabetes medications (such as metformin or a sulfonylurea such as glyburide). Talk to your doctor about the risks and benefits of pioglitazone.   FDA Approval Date: 1999-07-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ACTOSCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Diabetes headaches,muscle pain, swelling in legs and stomach, weight gain of 20lbs in two months, nightmares, head feels weird like it is going to explode, neck back and shoulder pain, hunger I am on a study for Diabetes and was put on Actos to start and will be doing an injectable in another month. They started me on 15mg, then 30mg and now on 45mg. I didnt realize that the terrible feeling I have been having was due to the Actos until I researched and found this site. I have headaches every day, my feet look like balloons and my shoes dont fit. I got weighed today and gained 20lbs in two months and have had a terrible hunger. My neck and shoulders hurt so bad, I cant even sit at the computer more than a few mintues at a time. I have nightmares every night and weird dreams. Also, have been feeling like I am coming down with something for several weeks, did not realize it was from the Actos. I called the study coordinator today to tell them about the hunger and swelling, and I thought it might be the medicine, but they said it was not and to control my hunger with rice cakes !!! I am so mad because I was losing weight before I started this medicine. I was 213lbs and now, two months later, I am 233. DONT TAKE THIS DRUG, IT IS DANGEROUS !!!!!!!! F 53 60 days
45 MG 1X day
9/1/2010
 1  Type 2 Diabetes - Marginal Headache, muscle pain, dizziness, abdominal pain, sore throat From being very fit just a week ago a now feel extremely ill and the only thing that has changed is taking this medication M 57 6 days
15mg 1X day
8/12/2010
 1  type 2 diabetic Swelling of feet and lower legs; rapid weight gain; extreme nightmares in early AM and hard to shake them off when coming awake, they can linger 5 to 10 minutes but you know you are awake; extreme sugar laden mucosa built up in head running down throat and I was not able to sleep until I dried this up with OTC anti-histamine pills which were usually about 12 in number and 3 different types in a day; fatigue. This drug must be very carefully monitored due to extreme side effects.It was good with the blood sugar levels and I wish it had worked for me. M 67 90 days
15 mg 2X day
8/11/2010
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Patient History
 1  Diabetes II to replace Avandia Shortness of breath, chest pressure (not pain), tingling in hands & fingers, fatigue, dizziness, bad leg cramps, swelling in feet & legs. All side effects getting worse. Dr took me off avandia 8mg (no side effects but drug pulled off market)and replaced with Actos. Now many side effects so I took myself off Actos. Dr said it was nothing and side effects were caused by stress so I'm also looking for new Dr. F 52 4 weeks
45 mg 1X day
7/29/2010
 1  Blood sugar levels high Weight gain and lack of energy. Was tired all the time and slept quite alot. I had lost weight back over the holidays and Dr. said to keep up the good work, then put me on Actos. After 6 months of taking this and constant weight gain and water retention I quit taking it yesterday. I did also start taking cinnamon capsules and limited my sugar and carb intake and have lost 2 pounds in one day. I am staying off Actos and will see my Dr. soon to let her know about this. F 62 180 days
15 1X day
7/23/2010
 1  TYPE II DIABETES RAPID WEIGHT GAIN,EXTREME SHORTNESS OF BREATH, ANEMIA, SWOLLEN LEGS AND FEET THIS IS A MEDICATION THAT SHOULD BE WATCHED CAREFULLY BY MD'S BUT THE 'PILL PUSHER' MD TOLD ME TO 'BACK AWAY FROM THE TABLE' AT MY CONCERN REGARDING MY WT GAIN. THEN ADDED INSULT TO INJURY BY ADVISING ME TO 'ELEVATE YOUR LEGS 4 TIMES A DAY' TO RELIEVE THE SWELLING, NEEDLESS TO SAY NEITHER OF THESE MEDICAL WISDOMS HELPED THE SITUATION. I HAVE STOPPED THE ACTOS AND HAVE LOST 6 LBS. MY SHORTNESS OF BREATH HAS NOT RESOLVED. I AM 'MAD AS HELL' BECAUSE I WAS VERY ACTIVE, PLAYING GOLF, GARDENING, NOW I CAN BARELY MAKE IT TO THE MAILBOX M 80 2 years
30MG 1X day
7/14/2010
 1  Type II A huge weight gain of 96 pounds that has turned me into an obese woman. I look ten years older. I now have huge thighs and butt. I started actos 15 MG and my doctor quickly moved me on to 30 MG. I can't lose the weight even though I have been off of actos for almost a year now. It did bring down my blood sugar but made me fat in doing so. F 53 18 months
30 MG 1X day
7/6/2010
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 1  too many side effects on metformin shortness of breath, loss of balance, heart palpitations, occasional swelling, headaches, eye strain and pressure, sinus pain, panic attacks, and severe anxiety, severe fatigue. I had no idea that this drug was the culprit. Doctor thought it was too much stress in my life overloading my system and causing panic attacks. The first one was on a road trip with the family and was so severe I felt unable to control the vehicle. Even after we were off the highway, I had waves of smaller panic attacks. Then severe anxiety set in. Had been having shortness of breath and kept thinking that I was really out of shape. I cannnot drive and have only been off Actos for two days. Hoping to feel better soon after reading the other posts. Am on Xanac for anxiety. I am shaking with my heart racing and palpitating just hanging around my house doing normal tasks. Drugs are bad!!! Every one of them has a side effect and you just never know what's going to happen. If you take this drug, don't ignore the slight side effects at first. They are a warning of something worse ahead! F 38 2 months
30 mg 1X day
7/3/2010
 1  Type 2 Diabetes Diarrea, vomitting, weight loss, pain. The diarrhea started after 2 days of starting the medication. Felt worse each day I took it, until finally the diarrea kept on, lost 5 pounds and the vomitting started. Called the doctor and she told me stop the med for 3 days, see how I feel and then start it again to see if I have the same side effects. The worst part, besides thinking that I was going to die, the drug had no effect on my blood sugar in the 6 days that I took it! I don't think that the pharmacutical company wants people to know all of the side effects of this drug (or maybe it's just me who can't tolerate most drugs). F 43 6 days
15 mg 1X day
6/30/2010
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 1  Diabetic Very rapid weight gain,severe shortness of breath, edema so severe my legs weep, fluid in the chest, swelling of feet, legs and hands. My doctors just blamed all my problems on obesity. I KNEW there had to be another reason and after 3 long years of being nearly bedridden I just STOPPED taking it. I CAN NOW WALK and BREATHE at the SAME TIME again!! I just keep checking blood sugars and control with food intake. F 57 3 years
45mg 1X day
6/25/2010
 3  Diabetes Weight gain of about 15 pounds. It has done a great job of bringing down my A1c from 8.2 to 7.1. However, I am really concerned about the weight gain. Weight went from being very stable on Metformin around 230 to 246.5. I have tried 4 different diets in the last five months, and have ramped up the exercise, but the weight is not coming off. I am going to talk to my doctor about switching or adding another med. F 48 8 months
15 MG 2X day
6/11/2010
 1  diabetics ACTOS KEPT MY SUGAR UNTIL CONTROL - BUT COULDN'T WORK OUT WHY MY SHOES ALWAYS TO BE STRETCHED BEFORE WEARING - SWOLLEN ANKLES AND WEIGHT GAIN. HAVE BEEN OFF TABLET NOW FOR 6 MONTHS - SHOES ARE NOW TOO BIG AND LOST 8LBS - NEVER GOING ON IT AGAIN F 58 8 years
45 1X day
5/30/2010
 2  Diabetes Type 2 weight gain...approximately 30#...need to stop because I've never been this heavy in my LIFE!!! F 45 6 months
30 1X day
5/27/2010
 2  Part of a double blind study Not sure if I have the Placibo or real Actos. However, gaining weight and can't seem to loose it, went from 245 to 250 to 255. Bounce around a bit to 251, but can't seem to get below that number. Ankles swell a lot more than before. Experience muscle pain in back and neck. Also weakness in arms that I never noticed before. Not diabetic, but part of a study to see if it effects patients with history of strokes. Had a TIA (Transient ischemic attack ) that took out my vision in the upper right quadrant for 4 hours. From what I read below in other cases, I'm moving off the study. Will come back in a month and let you know how this Grandpa is doing. M 63 90 days
45 MG 1X day
5/17/2010
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 1  Diabetes Type II Gained 45 lbs in the 3 years while stuggling to lose weight (with no luck) n Weight Watchers. Decided to stop the Actos 10 days ago and have lost 10.5 lbs already. Changed to Mmtaformin. I will NEVER take Actos again! F 49 3 years
30mg 1X day
5/13/2010
 1  Blood Sugar Control After my mother has been on Actos for about 5 years, the last six months she is experiencing significant abdominal swelling edema primarily of the legs and feet. How long after stopping Actos does water retention improve? When my mother first started using Actos I liked it because it effectively helped manage her blood sugar levels. Her Drs. (cardio/kidney) recently took her off Metformin (kidney impact), Actos (swelling/edema), and Avapro (too low blood pressure). We are using Glipizide since to manage her sugar control, so far that is working well. It is too soon to tell if the Actos is the culprit with the swelling but that is my main concern right now. My mother is very winded just walking around within the house short distances. I've seen questions on this site about how long it takes after stopping Actos for the swelling/edema to start to improve but there seems to be no clear answer. Today is day four and so far no significant improvement. I would love to hear from others on this topic about when we might see edema problems subsiding. F 85 5 years
15 MG 1X day
4/27/2010
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 1  Type II diabetes Almost constant runny nose. Some vision disturbances. Now have a dislocated clavicle and 2 fractures of the upper right rib cage. Most likely caused by using Actos, since there was no trauma involved. I would certainly not recommend the use of Actos. Although it has controlled my blood sugars really well and lowered my A1C down to 4.5, it is apparently way too risky for ones health F 67 2 years
45 mg. 1X day
4/25/2010
 1  Type 2 Diabetes Enormous weight gain (at least 50 lbs.), extreme fatigue, extensive swelling in ankles and feet to the point that my skin is cracking and I can only wear one pair of shoes. I described these side effects to two internists who dismissed them without investigation. One prescribed a diuretic, which didn't help at all. One week ago my doctor finally told me to discontinue Actos; I'm seriously hoping the excess weight will come off now and the fatigue and swelling will be relieved. This drug should be off the market. F 59 20 months
45 MG 1X day
4/18/2010
 4  Type II Diabetes Only side effect is loss of appetite. Keeps blood sugar under control. Before 190-200 after 94-124. I do miss my food but have no desire to eat now.. M 52 30 days
30mg 1X day
4/7/2010
 1  diabetes weight gain almost 25 lbs., swelling in legs ankles and feet. congestive heart failure, short of breath. A fib and hospitalized for 4 days regarding the new onset of congestive heart failure. I was put on the Actos by a doctor with good intentions to lower my A1c from the 8 that it was. It worked. My Fasting blood sugars about 150. But I noticed a change in the way I was feeling. I never have swollen ankles and feet. Elevating them did not help. Then the a fib. I took myself off this med. I will adjust my diet. There is no safe cure in Hypoglycemics. Will stay on my Glybride and Glucophage. F 48 78 days
15mg twice 1X day
3/28/2010

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