ACTOS Reviews (PIOGLITAZONE HYDROCHLORIDE)

Average Rating: 1.7 (361 Ratings)

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 BLOOD GLUCOSE REGULATORS

 Type: Rx Drug

  

ACTOS  (PIOGLITAZONE HYDROCHLORIDE):  Pioglitazone is a diabetes drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Pioglitazone is used either alone or in combination with other diabetes medications (such as metformin or a sulfonylurea such as glyburide). Talk to your doctor about the risks and benefits of pioglitazone.   FDA Approval Date: 1999-07-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ACTOSCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Diabetes Type II Weight gain of 12lbs in 11 months, and this is with a slightly better diet than before. I've had some fluid retention mostly in hands and ankles. Face is puffy. "Lethargy" is now my middle name. Currently on 15mg of Actos and 2000mg Metformin. In less than two months after taking Actos my BG numbers dropped to a very good range. This medicine helped, but at what cost? I would love to exercise more to help rid myself of extra weight; but since I've been on Actos, after 8 hours at the office, most days I just can't muster up enough energy to get off the sofa. F 47 11 months
11/30/2006
 1  To lower HbA1C Weight gain - at first it was a few pounds between doctor visits but the harder I dieted the more weight I gained. By the end I was on a 1000 calorie/day diet and I gained 30 pounds in 3 months! I finally wised up to this side affect. My doctor seemed unaware of the possibility and told me I was probably lying about my eating. My HbA1C did lower to under 5. But at what cost? I was on it for 18 months and gained 90 pounds. F 34 18 months
11/12/2006
 1  Type 2 diabetes WEIGHT GAIN!! 30 plus pounds in a year! Could not lose weight no matter what I tried. Spent a month on Nutri-System and gained weight. My blood sugar was always moderately high as well! This medication should be used on people with anorexia, not Diabetes. I have since changed to Glucophage! M 50 1.5 years
10/16/2006
 4  Diabetes Type II Severe muscle soreness especially in feet, lower legs, arms and breasts. My breasts are so tender that my poor husband has given up any chance of enjoying them anymore - can't stand even wearing a bra. Tingling and numbness in feet and fingers - shoes hurt after just a few hours so I wear sandals. Shortness of breath, heaviness of chest. Extreme blurred vision both with and without glasses on (light prescription). Always so tired even though I excersize and eat right - I take a nap almost every day. BG came down and was within normal ranges when using ACTOS, but I'm too tired to care. F 46 3 months
9/9/2006
 1  Diabeties Shortness of breath, Rapid heart beat, TIRED, extremely tired. fainting. Increase in Glucose levels Should be taken off the market. This is a very dangerous drug. M 6 months
9/7/2006
 2  poorly controlled diabetes terrible edema in legs hands feet, thighs bloating in belly and increase pulse rate, tingling in legs and feet, mood swings, shortness of breath low sugar weak episodes and sweet gravings. I have liver problems and I am afraid something will cause me increase problems as long as I stay on it. Yes it decreased the AIC but I think the side effect risks are worse. F 49 3 months
8/22/2006
 3  Type II Diabetes 30+# weight gain over last 18 months. Seems to control Blood Glucose levels effectively but at what cost physically ? Is there something out there that can control BG nearly as well without the weight gain problem ? M 69 2 years
8/1/2006
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 5  NIDDM Slight ankle edema Ha1C went from 12 to 5.2 in three years. Will come off Actos in a couple of months and see how I do with NO DRUGS. Originally tried Metformin but couldn't take the side effects so Actos is all I've take for diabetes and it has helped me control my BG to the point where I am (on my lab test results) testing in non-diabetic ranges. Can't wait to see how I do with just diet and exercise. F 42 3 years
7/31/2006
 2  Type II Diabetes Blurred vision, numbness in feet, high morning BG levels, gained weight. When I first started taking Actos, it did reduce my blood sugar levels and my A1C. I gained 20# in 6 months after being the same weight for nearly 8 years. I recently developed a blurry spot at the center of my vision and started doing some research about what could cause it. I learned that I probably have macular edema and Actos was a possible cause so I stopped taking it. My BG levels used to be 170-200 in the morning and now they have dropped to below 140. My eyesight has been coming back and the numbness in my feet has also been improving. I currently take Amaryl and Metformin and am on a low carb diet. M 40 3 years
7/18/2006
 1  Type 2 Severe muscle pain in both legs; swelling in ankles and legs gained 8 lbs in three weeks-stopped taking F 53 15 days
7/14/2006
 1  Diabetes 2, insulin resistent Exhaustion, increase in neuropathy pain, marked vision deterioration, mouth sores (tongue, gums, lips, roof of the mouth); sore throat & swelling of throat creating difficulty swallowing; gland pain with nodular swelling/evidence under jaws, down the neck, under the arms; added antihistamines to try & reduce symptoms for 11 days; Stopped Actos for 5 days to check if symptoms went away (most did, few did not); then tried for 3 days again; symptoms began to return & stopped. After stopped, all of my previously mild food allergies went into extreme, rapid reactions – almost causing ER trip. Immediate triple dose of Benedryl began slow reversal of symptoms. Very frightening. Actos also caused immediate gain of 5 pounds within 3 days - lost when Actos stopped. Did not wait for doctor to take me off of it – I stopped taking Actos as it was obviously life threatening for me. I hope my autoimmune system gets back to my normal. I had really hoped I could take it as my BG is quite high - well over 200 - even when trying to diet correctly. F 60 14 days
7/4/2006
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 2  Type II Diabetes Gained 75 lbs and did not change eating habits Leg and ankles are very swollen. I am going to the Dr today to see if she can change my med to something else. Ive been taking for 2 years. F 35 2 years
6/29/2006
 2  type 2 diabetes I felt shortness of breath, flu like symptoms, and nausea. I also gained 9 pounds in 2 months. My levels did get better but I also had drastically changed my diet and I started to exercise so this also could be helping me. I think the exercise and new diet is helping not the actos. M 38 2 months
6/22/2006
 2  type 2 diabetes I felt shortness of breath, flu like symptoms, and nausea. I also gained 9 pounds in 2 months. My levels did get better but I also had drastically changed my diet and I started to exercise so this also could be helping me. I think the exercise and new diet is helping not the actos. I will stop taking this medication NOW! M 38 2 months
6/22/2006
 2  Diabetes type II MY HUSBAND IS ON THIS MED WHEN HE WAS ON 30MG HE DID WELL WITH ALL THE SIDE EFFECTS BUT IT DID NOT BRING HIS BLOOD SUGAR DOWN. WHEN HE STARTED ON THE 45MG HE IS VERY MEAN ALMOST LIKE HE IS IN SOMEONE ELSES BODY CRAZY! SWELLING OF THE FEET AND LEGS, TIRED ALL THE TIME, EATING MORE. I CAN SAY THE DRUG STILL HAS NOT BROUGHT HIS SUGAR DOWN AND NOW THEY WANT TO START INSULIN WITH THE ACTOS. I WONDER IF ANYONE HAS DELT WITH THIS KIND OF RAGE ON THIS DRUG? IF YOU DOC WANTS TO PUT YOU ON ACTOS RUN THE OTHER WAY ITS JUST NOT WORTH IT. PLEASE EMAIL ME IF YOU HAVE HAD ANGER ISSUES WITH THIS DRUG THE DOC WILL NOT TAKE HIM OFF OF THIS DRUG SO WE ARE LOOKING FOR A NEW DOC. M 32 4 months
6/20/2006
 1  type 2 diabeties swelling of legs, feet, numbness in toes, I have been walking everyday for about 3 months, started taking 15mg of Actos about 5 weeks ago, legs and feet started hurting, went to diabetic classes where a doctor told me I had flat feet and that was why I was hurting, bought new shoes, bought 2 different arch supports, didn't help, doctor upped my dosage of Actos to 30mg a day, been on that a week, feet started swelling, can't walk because my feet hurt to bad, gonna call doctor monday, Actos not worth taking just so I can sit in a chair the rest of my life. Also some weight gain.. F 59 6 weeks
6/17/2006
 3  high glucose on Glipizide & Starlix Weight gain, 25 or 30 lbs in 3 months. Persistent cough. Fatigue. Glucose is in good range, but was nearly under control WITHOUT this drug. Now the risk from extra weight is more significant than having glucose 120 to 150. Risk of liver damage, too. Patients: you do NOT have to get the approval of your doctor to discontinue a medicine. Notify the doctor it's causing serious problems and not worth the risk - then ask if you should stop immediately or slowly wean off the drug. If doctor doesn't listen or take you seriously, find another doctor! M 58 3 months
6/13/2006
 1   Within two weeks of starting Actos, 30mg, I developed a pretty severe cough, as if I had something stuck in my throat.Scared my family. Three weeks later, I got this horrific tooth ache. Then I read that toothaches are a possible side effect. Stopped taking it, and within 2 days I saw significant improvements. M 59 30 days
6/1/2006
 1  Type 2 diabetes Sore throat, weight gain, and flatulence. I was so happy when my doc told me to stop taking this drug. All my symptoms disappeared within 2 weeks. F 52 60 days
5/30/2006
 3  Type 1 1/2 diabetes Was on 45mg for 3 years with a weight gain of 12lbs within the first 6 months. No more after that but couldn't drop the extra weight no matter how hard I worked at it. Since my diabetes has been progressive i went off actos after I started insulin therepy. I lost 7lbs within 3 months. my blood sugars went back up so I went back on 15mg and have gained back 4lbs already. I am going back off it since to me the weight gain isn't worth it to me. F 34 3 years
5/22/2006

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