ACTOS Reviews (PIOGLITAZONE HYDROCHLORIDE)

Average Rating: 1.7 (361 Ratings)

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 BLOOD GLUCOSE REGULATORS

 Type: Rx Drug

  

ACTOS  (PIOGLITAZONE HYDROCHLORIDE):  Pioglitazone is a diabetes drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Pioglitazone is used either alone or in combination with other diabetes medications (such as metformin or a sulfonylurea such as glyburide). Talk to your doctor about the risks and benefits of pioglitazone.   FDA Approval Date: 1999-07-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ACTOSCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Diabetes type 2 legs, ankles and feet swelling, always tired, sore muscles, leg cramps,weight gain - cant seem to lose even when I try, Flutter feelings in chest. I have been on so many meds so not sure if other side effects are from actos, probably I didn't relate these side effects with actos til now, because I had no idea of the side effects. I have wondered for a while why I was having these problems, I have been on a lot of meds. that I have gotton off of, because they were just causing more problems in my health. I am still having them, A few years ago I was diagnosed with fibromyalgia, and after reading this site I am wondering if its really the actos that could be causing the same symtoms as the fibro. I am on 3 diabetic meds, Actos, metformin and glipizide. I am thinking of stopping the actos and see what happens. It helped my blood sugars but they tell you to lose weight and excercise to keep sugars down, but how is that possible when you can hardly move? I really hate the drug industry!!! F 46 6 years
30mg 1X day
8/8/2011
 3  replacement for rosigliterzone Upper repiratory mucus,sore throat, blocked eustachian tubes, mild headache, aching legs and a general tiredness. None of these symptoms were present when prescribes rosigliterzone. M 73 12 months
30mg 1X day
8/6/2011
 2  to get blood sugar down Aching all over body, weight gain of 20 pounds in 3 months, hard time going to sleep F 64 3 months
15 mg 1X day
8/4/2011
 2  Type 2 Weakness all over. Pain in knees and leg muscles, including leg cramps. Lightheadedness and shortness of breath after going up stairs. Spoke to my Doctor many times about these issues and was assured that Actos was not the problem. Have stopped taking now for three weeks and these issues are going away. Need to find a replacement for Actos that works like Actos but without the side affects. M 58 2 months
45 MG 1X day
8/4/2011
 1  Type II Diabetes Experienced horrible leg pain, especially behind knees down the back of my lower legs. Doctor had no answers for me. Could hardly get up from seated position, in and out of a car, and in and out of the shower. Once coming to a standing position from being seated, I would have to stand for up to 30 sec. before I could walk. The first 5 min. of walking was very uncoordinated and then finally I could walk normally. So grateful to come across this site to see that others have experienced the same side effects. This has been so frustrating. I thought I was getting ovarian cancer with all the bloating or MS with the leg issues. Stopped the drug 6 days ago and have seen some relief. Have been able to get up from a seated position and start to walk without having to wait several seconds. Still a bit uncoordinated for the first few steps. Weight has increased while on this drug so I am hoping that I will have good results from having stopped the medication. Since I started with the bad pain back in February of 2010, and never attributed it to this drug, I am hoping it has not caused irreparable damage. I see that others have had good results after stopping Actos so that was very encouraging to read. I didn't see my symptoms listed as common side effects with Actos so I never suspected the drug as the cause of my problems. F 61 2 years
45 mg 1X day
7/31/2011
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 3  diabetes 2 20 pound weight gain, body aching all over, hard time breathing (like allergies), Actos has brought down my blood sugar levels. F 64 3 months
15 mg 1X day
7/27/2011
 2  Type II diabetes Gained 25 lbs although there was no change in diet or exercise. In fact, I tried eating fewer calories and exercising more, but kept gaining. I also lost focus and began having symtoms of depression. Asked Dr if I could stop 2 months ago. Have begun losing weight. But it is slow. Also taking MUCH more insulin now than I did before going on Actos. Not sure what it did to my insulin production. F 62 18 months
30 1X day
7/27/2011
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 3  Type 2 Extreme weight gain mostly in my hips and butt. I am pleased that I do not have to take insulin yet. F 58 3 years
30 MG 1X day
7/17/2011
 1  diabetes previously listed in May--this is a follow up Have now lost 20 plus lbs since going off it...lower body fat, feeling much better. gym workouts with trainer have helped alot...never thought I could lose weight again but I did! F 62 18 months
30mg 1X day
7/10/2011
 1  Type 2 diabetes Gained 15 pounds in 5 months, hunger, craving sweets, tired all the time Stopped actos a few days ago - will see a new doctor. Worked good on The sugars but the weight gain just makes everything worse. F 56 5 months
30 mg 1X day
6/25/2011
Email
 1  Type II diabetes Knee and leg swelling, pain. Became basically immobile and installed handicap bars in shower, began investigating early retiremet and moving into a condo. Then went off actos and within 4 weeks I am amazed. Dropped 1/2 shoe size already (had gone from a 10, to 101/2 to 11 wide in 2 yrs) & looking forward to getting into some of my old shoes. Can now see and feel bones in my ankles and knees. Family had me seeking psychiatric help for depression, didn't do anything around the house, go anywhere, etc. But it was the leg pain and inability to ambulate. I had to save all my energy to make it through work with vicoden. Cannot' believe the difference. After a month I am not even taking tylenol!! Glory be! F 55 2 years
30 mg 1X day
5/23/2011
 3  Type 2 Weight gain (85 pounds) that settled mostly in my butt, thighs, hips and upper arms. Some muscular pain during the early weeks and when she upped me to 30 MG form 15 MG I did not pig out while taking this medication. It works great to lower blood sugar. If I needed to take 45MG I would, even though it probably would make me morbidly obese. F 58 4 years
30 MG 1X day
5/7/2011
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 1  diabetic I am very upset. Do not take this. I now have macular edema (swelling behind my eye) and if it does not stop I may go blind. This is also very costly. iw as not told of this side effect when my doctor prescribed this. I am really mad and scared. What will I do now? F 55 3 years
15 mg 1X day
4/25/2011
 1  Type 2 diabetes Weight gain esp. after dropping metformin..approx 30 lbs., , stomach bloating, temp anemia, shortness of breath, unusual feeling of fat deposits in thighs, upper arms, hips, high body fat readings Dr. took me off recently, it felt like the fat accumulation would not stop., esp. after I was off metformin.I am careful about following a diabetic diet & modest excercise but nothing helped & my A1c increased..Now taking metformin & Onglyza--not as effective so far..joined a gym & have a trainer to see if I can lose weight & fat accumulation & build muscle.. never taking it again! F 62 18 months
45 mg 1X day
4/21/2011
 1  type II diabetes 20 pound weight gain, neck and shoulder pain, headache, extreme fatigue, lethargy, frequent urge to urnitate, loose stools, disturbed my sleep patterns and when I did sleep, I have strange and vivid dreams. I know it's the Actos because it's the only new drug I'm taking and the problems started after I started using the Actos. I was on Avandia for two years prior to switching to the Actos. I had few issues with Avandia and my sugars were well controlled. I got paranoid about Avandia after seeing all the bad press regarding that drug, so asked my Dr to switch me to Actos. BIG MISTAKE!! If you want to feel extremely tired all the time and and walk around like a zombie, take this drug. I've stopped taking it and will see how I feel after a week. Have a followup with my Dr in 10 days and will discuss switching back to Avandia or trying another drug. M 59 6 months
30 1X day
4/13/2011
 3  To lower blood sugar Only known side-affect is weight gain. I walk a brisk 3-4 miles every day, burning sometimes 600 calories and still am gaining weight. I feel heavy and don't eat abnormally, but can't shake the weight...in fact, it keeps adding on. I informed my Dr that I didn't want to take it anymore and he agreed, so has me closely monitoring my blood sugar to see how it behaves on just Glumetza (Metformin). M 62 1 years
30 mg 1X day
3/22/2011
 1  to lower blood sugar rapid hair loss, soreness in shoulders, weak knees. works well on the sugars F 54 2 months
15 2X day
3/15/2011
 1  diabetes II weight gain, painful swollen ankles and legs, belly fat I feel so much better after stopping this drug. I can actually see my ankle bones again and my legs are not as swollen. F 64 2 years
1X day
2/20/2011
 1  type 2 diabetes I am adding to my two previous posts of 10/5/09 & 1/20/10 which outlined the horrid side effects of Actos. I still have intermittent arm/shoulder/finger pain and weakness. I did not have tooth problems, but found something interesting At the time of my problem, I contacted Takeda and asked what specific problems people have had with teeth (a side effect listed on the drug label). They had no idea. BUT I recently learned that there are tiny ligaments which help hold your teeth in, and it dawned on me that if this hell-drug damages ligaments and tendons in other parts of your body, why not teeth? We will NEVER get an answer from the FDA or Takeda, so we must keep sharing and searching on our own. Everyone, PLEASE file a report with the FDA. It's easy and you can do it on-line. This is the only way to document bad reactions. F 64 14 weeks
45 mg 1X day
2/18/2011
Email
 4  diabetes 2 it kept me up going to the toilet a couple of times a night so l kept it to 1. over time my hair has been getting thinner, just lately my knee has swollen and my ankles have been stiff. then the muscles in my leg started cramping and my weight went up a stone my legs felt very heavy and weak, so l have left it off for a week now and my leg it getting better and my hair isnt coming out like it was. after reading a couple of weeks ago the comments of actos on the web it has made me realise all the things that have been going wrong with me is down to actos, although l am still on januvia. which l really dont like. but have to take something. F 64 18 days
15mg 2X day
2/12/2011

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