ACTOS Reviews (PIOGLITAZONE HYDROCHLORIDE)

Average Rating: 1.7 (361 Ratings)

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 BLOOD GLUCOSE REGULATORS

 Type: Rx Drug

  

ACTOS  (PIOGLITAZONE HYDROCHLORIDE):  Pioglitazone is a diabetes drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Pioglitazone is used either alone or in combination with other diabetes medications (such as metformin or a sulfonylurea such as glyburide). Talk to your doctor about the risks and benefits of pioglitazone.   FDA Approval Date: 1999-07-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ACTOSCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  switch from Avandia to Actos by Dr. I have fibromyalgia and since I started on Actos I've been in an almost constant fibro flare up with fatigue, muscle aches and pains. Also my allergies have kicked up big time with runny nose and sore throat like never before, I suspect this Actos may be responsible. Feeling like c*rap, not sure I'm sticking to drug, unless side effects go away. No weight gain, but no weight loss either! Taking 30 mg Actos F 55 1 months
9/14/2007
 1  TYPE 2 DIABETES WEIGHT GAIN, WEIGHT GAIN AND MORE WEIGHT GAIN. THE MORE WEIGHT YOU GAIN THE WORSE YOUR DIABETES GETS. NO MATTER HOW HARD I TRIED TO LOSE ANY WEIGHT, INCLUDING DIETS AND ACTIVITY, I COULD NOT LOSE WEIGHT. I WAS ONLY TAKING 15 MG DAILY OF THIS DRUG. I HAVE A FRIEND WHO WAS ON 45 MG PER DAY AND SHE GAINED WEIGHT MORE QUICKLY THAN I DID. IN TWO YEARS OF USE I BALOONED FROM A HEALTHY 190 TO 250 LBS. ABOUT THREE WEEKS AGO MY PHYSICIAN CHANGED ME TO JANUVIA AND TOLD ME TO QUIT THE ACTOS, NOT ONLY BECAUSE IT WAS IN A CLASS OF DRUGS THAT COULD CAUSE HEART PROBLEMS BUT BECAUSE IT COULD BE MAKING ME RETAIN FLUIDS AND GAIN WEIGHT. WOW, IN THE THREE WEEKS SINCE I CHANGED MEDICINES I HAVE LOST 12 POUNDS. WHILE JANUVIA IS RATED WEIGHT GAIN "NEUTRAL", THERE IS ANOTHER DRUG OUT NOW CALLED BYETTA WHICH IS HIGHLY RECOMMENDED AND WHICH CONTAINS A CHEMICAL WHICH CAUSES WEIGHT LOSS IN MOST INDIVIDUALS. SO IN MY HUMBLE OPINION, UNLESS YOU ARE A RAIL...DO NOT GO FOR THIS DRUG AND ASK FOR ANOTHER. I DO WANT TO ADD, TO BE FAIR, THAT ACTOS DID AN EXCELLENT JOB CONTROLLING MY BLOOD GLUCOSE AND AN INCREASE WAS NOT REQUIRED. M 66 2 years
9/13/2007
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 1  Type 2 Diabetis Severe weight gain, unable to lose any weight after diet and excersize. Depressed, dry cough, dizziness, bloating, left ankle swelling at night. Was on this drug for about a year. Helped for a little while but with all the adverse side effects I just couldn't take it anymore. Would not recommend anyone take this drug. F 52 1 years
9/12/2007
 1  Diabetes Type 2 weight gain , dry cough with trouble breathing while laying down to sleep I have never been allergic to any meds and just started taking 10mg actose added to my already 2000mg metformin and within 2 days of starting it I had problems with dry cough and not being able to breath at night without sitting up,I was waking up about every 2 hours with this problem, I did this for 2 weeks and decided to stop taking it and within 2 days was back to normal and able to sleep allnight, I also gain 5lbs in 2 weeks M 45 14 days
9/6/2007
 1  To Lower A1C Rapid unexplained weight gain (30 Pounds so far), possibly due to fluid retention. Serious bloating in the belly and rapidly increasing fat in the midsection. Extremely tired all the time. Dizzy. Vertigo. Cholesterol readings suddenly through the roof (277+ up from 170). Difficulty breathing at night. Shortness of breath. Cough. I stopped taking it and asked doctor to put me back on Metformin. Doctor refused as A1C is now 5.7. Time for a new doctor. It has been reported that ACTOS and AVANDIA are very dangerous for the cardio-vascular system. 1 out of every 50 patients on either of these two drugs will experience heart failure within 26 months. M 58 90 days
9/4/2007
 1  type 2 diabetes major weight gain (100 pounds in 2 yrs), swollen ankles, constant ache in hips, increases after short walk ... after reading all these comments i may stop taking it. i really don't know of any benefit from this drug. F 63 2 years
9/2/2007
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 3  taken off of avandia and byetta i have been taking actos plus for met for about a month no weight gain but my lips and tongue are on fire and have had to use inhaler more than once i also have a burning headache and eyes feel strange and have noticed some heart palpitations not sure if i will continue i am allergic to sulfa and apirin and the side affects almost feel the same I wil see Dr soon and discuss blood sugars have decreased but not sure it is worth it F 54 20 days
8/31/2007
 1  diabetes, type II I've only taken this for two days and have had chest pain all day today. Tonight my sleep was interrupted and I have a bad, sharp headache with pain running down my neck. I started a dry cough tonight and feel very "weird" and panicky. I am stopping this med immediately. I will be getting my butt up to exercise in the morning. have already changed my diet this last week to Dr. Bernstein's Diabetes Solution diet. Numbers were coming down fast but doc put me on this in addition to 2000mg. glucophage that I was already taking. Sorry. Not taking any more of this stuff. F 47 2 days
8/31/2007
 3  Type 2 None - yet. Only 1st day @ 15mg. Comments from other people below are interesting and alarming. Also taking Metformin (2000) w/Actos. Have been taking Metformin for 4 weeks & BS has come down, but not enough because I still have terrbile blurry vision. Have been to eye specialists and have to wait until BS stablizes. Any help ideas for vision until then?? F 46 1 days
8/28/2007
 2  lower blood glucose i have only been taking actos for one week but i have begun to have what i can only assume are severe hot flashes, a throbbing pain in my groin area, leg pain and periods of feeling as if i may pass out. this does not last but an hour or so at a time but i am very concerned about continuing this medication. i am also taking glucophage and i have not seen a change in my blood sugars since beginning actos. is a week long enough to see a difference? after reading messages on this site i am even more concerned. F 52 1 weeks
8/28/2007
 4  Type II Diabetes Trouble controlling weight, Tired all the time, I've developed High blood pressure. Untill recently I thought this was a great drug. Now I'm not sure I just found a bunch of web sites that talks about heart problems with Actos. I've been taking actos for approxomately 4 years and have had high blood pressure for roughly 3 yrs...Do your research before taking this. Now I'm seeing a cardioligist I'm very concerned M 47 4 years
8/14/2007
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 1  Type 2 diabetes Extreme swelling of lower extremities up to and including the knee area. Also have noticed unilateral pain in ankles, knees, hips, and thumbs. Fracture of bone in R foot. The swelling appeared suddenly over a period of three days or so. Doctor discontinued Actos immediately. No replacement. Swelling has disappeared, but the joint pain has not. Have not seen the doctor since I realized the pain was probably related and have not discussed it with him. I also noticed some increase in cravings for sweets. Since I just recently stopped taking the actos I have not had an A1C. No replacement, just the regular glipizide twice a day. F 64 8 days
8/13/2007
 1  TO LOWER BG IN THE MORNING sever swelling of feet and ankles,lowerleg seemed to feel like burning ,but must just be the numbness,blurred vision,temper,weight gain,headache.husband not happy with me on this medication.. only type 1 diabetic and the doctor put me on this since avandia was taken off. i hate the way i feel and can't stand the swollen ankles and coldness on the lower leg and feet.I have stopped takeing it only half of 15mg one day and none today and i already can see better and legs not to bad yet. bg not bad this morning 7.1 and after lunch was only 6.5 . i am off on holidays for a week , even tho i need a wheel chair i still will not take this anymore , will see the dr.when i get back she will not be happy ,but am not happy with her. wish me luck. F 66 2 weeks
8/13/2007
 1  type 2 / pcos tuesday started- next day ankles and eyes swelled-big puffy face- thursday whole body is swelling stomach is huge- left leg pain shuffling hard to walk -very hot all over past 2 days - tingling feeling - was on metformin 1500 only was very tired at 10 pm every night went off for a week to see if i can stay up past 10 pm- and yes i could- told dr and she switched me to astos saying my a1c went up a point and triglyc have been high to see if actos will be better - this is day 4 and no way i am not taking any more actos it is horrid and am waiting to hear from the dr - iw ill go back to metformin and go to bed early F 44 4 days
8/10/2007
 3  Type II I have pain in my Joints. I have gained weight. I have been taking Actos for two years M 53 2 years
8/8/2007
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 1  type II 70 pounds in 2 years, thought I was going through some mid-life crap - started taking an anti-depressant, dizziness. Just plain tired - can't get out of my own way. shortness of breath. I have felt like crap for 2 years - didn't know it was the actos until the doctor "upped" me from 30mg to 45mg and my feet/ankles swelled to balloon status and i found this website - the actos could explain everything - thanks! I am going to stop taking it and try something else - my life since actos has been miserable. M 49 2 years
8/3/2007
 3  Type II I was 155 3 months ago. Now I'm 165 because of this drug. I'm thinking of stopping and seeing if exercising will control my sugar. I don't take any other drugs. M 3 months
7/27/2007
 1  Diabetes Type 2 Weight gain big time, 15 lbs in 3 months, swelling of the ankles, thining of hair and sleepless nights. I take 30 mgs, my doctor doesn't think this med is the culprite but beg to defer. If my insurance cover Byetta I will ask the Endocrinologist to prescribe it. I've heard good things about it, specially the weight lose. F 46 90 days
7/22/2007
 2  Type II Weight gain, dizziness. Family med doc with personal interest in Diabetes didn't like combo of glipizide/metformin I'd been taking and switched me to actos/metformin. Actos at 15mg let my numbers rise, went to 45mg in a couple months. Gained nearly 30# in about nine months. Have to eat less to maintain at that weight. Intend to quit. HA1c 5.7/6.1 over the years. Will see an endocrinologist M 64 11 months
7/21/2007
 1  Type II Diabetes Weight gain of about 40-50 pounds in the last year, constantly hungry, feet and ankle pain/swelling, gum bleeding/tenderness (it about kills me to have my teeth cleaned!), migraines and heart flutters with racing at times. I changed to Actos because Metformin gave me diarrhea but at this point, I'd rather have that. I need to lose weight and all I've done is gain, without really changing my eating habits. Forget about exercising because I'm too tired now. I thought it was just me until I read some of the feedback on this website. I know I'm not crazy now. F 45 1 years
7/17/2007
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