ACTOS Reviews (PIOGLITAZONE HYDROCHLORIDE)

Average Rating: 1.7 (361 Ratings)

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 BLOOD GLUCOSE REGULATORS

 Type: Rx Drug

  

ACTOS  (PIOGLITAZONE HYDROCHLORIDE):  Pioglitazone is a diabetes drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Pioglitazone is used either alone or in combination with other diabetes medications (such as metformin or a sulfonylurea such as glyburide). Talk to your doctor about the risks and benefits of pioglitazone.   FDA Approval Date: 1999-07-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ACTOSCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  high blood sugar , 70 + lb weight gain!, not even diet pills from endocrinolgist helped me lose, thyroid issues, swelling of feet and legs, excessive upper respiratory infections,shortness of breath ,when I got my A1-c in line (6.1)and KEPT it there , asked caregiver if i could come 'off' the ACTOS,as i had read some 'bad press' on the drug, he said "NO, lets not mess with a 'goodthing' I assumed he knew what he was doing...recently I have had severe shortness of breath and upper respiratory problems, my 'new' P.A.did a 'pulmonary' functin test, which I failed, they gave me a'breathing treatment' which worked great, then gave me an allergy shot' along with medicated inhalers (one for asthma like symtoms, the other just a 'rescue breather' she quickly took me OFF the ACTOS,( by this time I was up to 45 mgs. she said lets get you OFF this stuff AND hope too much damage has not already happend it looks like you may already have an enlarged heart due to this med." I am scheduled for an echogram I am LIVID that my health has been compromised by this drug. My husband wants to choke the caregivers who insisted on keeping me on it. I am overweight and consistantly complained to ALL my caregivers they just offered 'diet pills' which did little more than make me run around like the EVERREADY BUNNY !that I eat LESS and gain weight, even though i try to swim daily (summer) I can't 'walk' for exercise because of hip pain as well as muscle pain, I now see where other patients complaints parrot mine, even my upper respiratory condition and breathing issues. I can only hope that some of these symtoms are reversible my A1-C has remained 6.1 for over a year and they still didn't stop the ACTOS!! until Pam my P.A. noticed the ACTOS listed on my chart and told me to STOP IT as she was concerned I might have an enlarged heart..Ithen told her my other symptoms, she didn't get too involved with that, but is sending me for a echogram to see if my heart is damaged. anyone reading this... F 61 3 years
5/21/2008
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 3  Diabetes 2 Weight gain of 50 pounds in 6 months. Took it for about 8 years. Finally stopped it about 8 months ago and have slowly and easily lost the extra 50 pounds gained. Several times I had the feeling of being bloated to the point of feeling like my face would explode. F 57 8 years
5/9/2008
 1  diabetes type 2 One year of Emergency Rooms and hospitalization for severe stomach pain and uncontrollable nausea. Every Gastrointerology test known to man and it was the Actos Lost every tooth! I started on 15 and it did lower blood sugar. Then Dr. increased to 30, then at 45 started my worst health year ever with non stop nausea. M 71 2 years
5/4/2008
 1  type 2 I had dizziness and I ached all over like I was ran over with a truck. I couldnt walk a straight line. I asked the doc about this and he said there was no report of any kind along these lines. I stayed on this for about 5 months and then went off of it without permission as I felt like $hit. This stuff was AWFUL. It took 5 months to lower my BG about from 13 to 7. I went off of it, ate a high protein, low carb, high good fat diet and got to 6 A1C by myself within a month. This drug sucks big time. Do some reading on this low fat nonsense. And read about the Cholesterol Myth propagated by you guessed it, big pharma. I believe in doing things naturally. There is no reason why they can't find a CURE and stop beating around with symptoms only. Too much money to be made? And food companies are as much to blame by adding canola, synthetic fats, frutose and sugars to everything. And while I'm at being ticked off, I'm not fat, so diabetes can strike anyone. As soon as companies switched from coconut oil in the 50s to all this other nonsense oils, diabetes took a leap in cases. It's about time people started demanding that these companies stop poisoning us. F 56 5 months
4/29/2008
 2  Type II Diabetes Muscle pain/weakness, lethargy, fatigue, constant hunger, weight gain. My doc added actos to 2000 mg of metformin and 2 mg of amaryl in order to try to bring my morning blood sugar readings down. While it has helped minimally, it's not worth it. F 43 120 days
4/28/2008
 2  Type 2 Diabetes I was prescribed 30 mg per day. It did help my BS but the side effects where horrible, weight gain ,blood pressure went up,tired all the time...etc. Been off now for 7 days. Feel great. Weight is coming off , BP is good feel like a new man. M 50 7 months
4/20/2008
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 2  Type 2 Diabetes It controlled my blood sugar but I experienced 40 pounds of weight gain. My doctor has recently switched me to Byetta (2 months ago) and I have lost 10 pounds since going off Actos F 47 3 years
4/10/2008
 1  Polycystic Ovarian Disease (PCOD) Massive weight gain, nausea, headaches, unhappiness Being diagnosed with an unheard of disease like PCOD shocked me. The doc told me the side-effects of the disease would be infertility, weight gain, and insulin/sugar problems. My doc then put me on Metformin. After experiencing immediate side-effects of severe light and sound sensitivity, nausea, and aches, my doc decided to switch me to a "less harsh" drug: Actos. After the initial side-effects, I started to feel okay. I had, however, gained 40-50 lbs. in a span of 8 months. Trainers say that I'm on the verge of being severely overweight. Before being diagnosed, I had a fairly stable weight at about 130...I look back in pictures and compared to now, I felt pretty darn skinny back then. It hurts because people see me in my present state and they don't understand that this is me at all. This isn't normal. I exercise regularly and eat healthy, with no avail still. A couple weeks ago, I began having waves of nausea out of nowhere. My last appt. I talked to my doc about the weigh F 18 1 years
3/27/2008
 1  Type II diabetes Chest pains, bloated feeling after meals, weight gain, puffiness in face. Have stopped taking this drug, may go back to Metformin. F 54 3 months
3/23/2008
 1  My blood sugars were not good. weight gain of 20 lbs in 5 months. This medication did bring my blood sugar levels down, however after being at the same weight for years and not changing my diet at all, I have been gradually gaining since I started this drug. I am on 30mg a day with metformin and insulin. I can't take the weight gain, I am miserable with a huge swollen stomach and sweet cravings. I am going to quit and ask my doctor about byetta. F 57 5 months
3/22/2008
 1  Type II Diabetes Tremendous weight gain over 100 lbs. I was on this drug for several years and had horrible swelling of my legs, hands and midsection. Persistant, productive cough. Muscle pains, lethargy. Insatiable appetite. I quit taking Actos on my own right after I had a doctor's appt. where I weighed in at 298 lbs. Before I started taking it I weighed 170 lbs. I read on the internet that it caused edema and weight gain. I quit taking it on my own, without my doctor's knowledge. Three month later and 36 lbs lighter I had the best A1C test I have had in years. My doctor was thrilled, and asked what I had done to achieve that, and told him I stopped taking the drug he prescribed. He was not happy, but 6 months later I am no longer ravenously hungry, 48 lbs lighter, have more stable blood sugars. I also have recently started eating natural and organic foods...and stay completely away from ANYTHING with high fructose corn syrup or hydrogenated anything. I am 55 years old. Last year at this time I felt 90. I now feel closer to my chronological age. I still take glucophage and insulin, but I am working toward becoming drug-free if I can. I would NEVER recommend Actos to anyone. As a side note, the product F 55 6 years
3/21/2008
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 1  Diabetes Type 2 Aches and pain, extreme tiredness, anemia, possible asthma and a thyroid problem. 15mg Actos 2000mg Metformin After taking approx 1 year I now have anemia and I hurt so badly my Dr gave me Flexoril and Lortab for pain. I do not like taking any pain medication so have been using the Flexeril and Extra strength tylenol to make pain bearable. Dr. sent me to a GI and my gynecologist for 'loss of blood resulting in anemia'- nothing has been found. This morning I was rechecking the side effects and found anemia to be listed, along with extreme tiredness, aches and pains weight gain,etc. I have them all, including possible asthma and am scheduled next week for biopsy of my thyroid- which came about because I have a choking feeling-also mentioned as being a side effect. This past year has been the worst I have experienced healthwise, and I will be stopping Actos as of today. I hope for no other complications, but now worry about my heart and liver. F 43 12 months
3/7/2008
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 2  control sugar Very bad muscle, hip and joint pain.Swelling knees, hands,legs and ankels.I do not advised anyone to take Actos.I am 43, but I feel like I am 83, my doctor's appointment is in two days, and I can't wait to try some thing else!!!!! F 43 1 years
3/6/2008
 3  Diabetes Anemia I have mild anemia. The lab report said it could be a side effect of medication. Have other people taking Actos noted Anemia? M 30 3.5 years
2/17/2008
 1  Type II Diabetes Muscle pain (lower legs), weight gain (5 lbs in 3 weeks), dry cough, bright sun glare now bothering me, headaches in the evening, sudden drop of BS (70-80 mg/dl)at 12:00 noon daily,feeling bloated all afternoon shortly after eating even a light lunch. With 15 mg Actos I'm also taking 2.5 mg Glyburide and 1000 mg Metformin. Will stop taking Actos today because I was doing fine with just Glyburide and Metformin. M 54 3 weeks
2/17/2008
 3  Type II taking actos has lowered my bs but i have experienced sudden weight gain ... over 50 lbs in 2 yrs and that is with cutting back, severe pain in feet, knees and hips, edema especially feet and legs after reading the comments today, I'm calling my Dr to discuss removing Actos from my treatment plan F 41 30 months
2/6/2008
 1  Type 2 Diabets Chest pain, heaviness in leg, vision problems and only been on actos for 3 days. Only been on actos for 3 days and already having problems. Besides the chest pains, my BP has gone out the roof. Was fine 4 days ago. I'm not going to worry about weight gain, because I'm off actos today. The Dr. may not be happy but he's not the one having the side effects. In the 3 days my BG even went up, but that's not saying this drug might work for others. Over 24 hours since the last pill and the chest pains are almost gone. Hope no permanent damage. Great Epilog: Actos cured his diabetes, but the side effects killed him. "AMEN" M 73 3 days
2/2/2008
 4  Type 2 Diabetes I gained weight after taking 30mg of Actos but for me its a wonder drug. My blood suger came down and has stayed within acceptable limits ever since. The small weight gain versis having high blood suger is worth it. M 49 2 years
1/27/2008
 5  diabetes M 80
1/22/2008
 1  Type II Diabetes accelerating weight gain I took this along with Avandia. I dieted and dieted but could do nothing but gain. Exercise became difficult with the weight gain, and I was having heart palpitations. I gained 130 pounds, then dumped my doctor and this medication, found someone who was willing to give me insulin instead of oral meds. I've lost all the weight and more with diet & exercise, so I am positive the meds were making me gain. F 38 18 months
1/15/2008

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