ACTOS Reviews (PIOGLITAZONE HYDROCHLORIDE)

Average Rating: 1.7 (361 Ratings)

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 BLOOD GLUCOSE REGULATORS

 Type: Rx Drug

  

ACTOS  (PIOGLITAZONE HYDROCHLORIDE):  Pioglitazone is a diabetes drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Pioglitazone is used either alone or in combination with other diabetes medications (such as metformin or a sulfonylurea such as glyburide). Talk to your doctor about the risks and benefits of pioglitazone.   FDA Approval Date: 1999-07-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ACTOSCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Type II Diabetes None Reduced blood sugar level from an average 600+ to 140 w/o really modifying diet or excercise M 67 4 years
7/13/2007
 1  Type 2 diabetes Weight gain of 70 LB in last year since increasing to 30MG, severe swelling in ankles and legs, flatulence, anemia, extreme fatigue, and fractures in both feet, low blood sugar at times and craving of sweets I tried to lose weight and tried Weight Watchers and just kept gaining weight, doctor says to stay on it even though it causes weight gain as A1C IS 5.8. Doctor says I must not be following the diet correctly. F 54 5 years
7/13/2007
 1  Type II Diabetes Weight gain, pain in all major joints but especially feet and ankles, shortness of breath, blurry vision, lethargy, tightness in chest, tooth pain I just started this a week ago and I do not have the emotional energy to deal with these side effects! This is crazy! It's very simple, if my doctor won't let me off of these, then it's time for a new doctor. My husband is very upset at the side affects and is very worried about me. F 49 5 days
7/9/2007
 1  Type II diabetes Weight gain of 4 lbs. in 1 week. Fast heart rate. Shortness of breath. Bad migranes. I rarely experience migranes but I woke up one night having a horrible headache and shortness of breath. I've also had an increased heart rate since I've been on this med...not to mention weight gain. F 55 8 days
7/4/2007
 2  Type 2 diabetes Like alot of others I have had weight gain, swelling in ankles, sore throats, constant "sweet" gravings, bloating of stomach,tiredness, dizziness and occasionally vertigo and shortness of breath. My Doctor seems to be more happy with me on this drug than I do. Yes my numbers are in a pretty good range with this med, but I'm miserable. There has got to be a better way. F 54 6 years
6/25/2007
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 3  Type II diabetic I have experience extreme fatique, swelling in my ankles and feet. Also joint pain to the point of not being able to walk. Have had some severe dizzeness. A1C is now at 6.1 but cannot loose weight. Dr told me to stop taking the meds immediatly and increse my Lantis M 54 3 years
6/22/2007
 1  Type II Diabetes My husband has had weight gain and tremendous swelling of his left leg. Now that I see other people on Actos are experiencing the same thing, I wonder if it's the Actos. He went to the doctor, but was just told that the swelling was probably due to age. He's 59. M 59 3 days
6/17/2007
 1  type II diabetic weight gain and enlarged heart M 47 7 months
6/16/2007
 3  Glucose Control Worried about side effect on heart as reported in the news for Avandia M 48 2 years
6/15/2007
 1  A1c was 7.0 Have experienced weight gain of 10 lbs in the last two months. Continually hungry. Very tired and nervous. Have had fluttering of the heart. Noticed sometimes my eyesight is not as good. Noticed weight gain after going from 15mg to 30 mg Taking 30mg. F 64 3 months
6/12/2007
 3  type 2 diabetes Thinning hair and hair beakage, weight gain. I took 15 mg for a few years and didn't really notice any problems until dr took me to 30 mg last summer to lower my A1C level. I've gained about 35 pounds since then. I could not account for my hair loss and breakage before but since the dr increased my dosage, along with the weight gain there is an increase in my hair breakage and its beginning to thin on top. Has anyhone else had this sympton? F 59 5 years
6/11/2007
 2  Type II Diabetes Been taking Actos 45 mg (along with Glipizide 10 mg.) Glucose level is under control- I give some credit. But I have GAINED about 25 POUNDS Thinking of totally stopping Actos. Doctors seem to be focused on A1c but not about the weight gain at all. M 50 2 years
6/9/2007
 5  Type 2 None Actos brought my BS readings to 105 or below all the time. Best if I take in the AM. M 47 3 years
6/7/2007
 1  Type 2 Diabetes The main side effect that I experienced was dizziness and vertigo. I flew on a commercial jet while taking Actos and I thought I was going to throw up every time the plane turned. I quit taking it even though my Dr. told me to keep taking it when I reported my side effects to him. I found that I am better off with a low carb diet, exercise, and Metformin. M 40 2 weeks
5/24/2007
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 3  Type II Started on 30mg but increased to 45 mg in second year due to A1C slightly above target of 6. Increased Appetite, Weight Gain yr by yr about 4 lbs with better diet and moderate exercise regimen. MAJOR lethargy problem along with reduced sleep quality is a serious concern. Also had long term foot (fascitis) inflamation problem within months of starting Actos. Never had any problems prior. Also taking Hyzaar to get avg BP down to around 125/70 and Simvastatin (Zocor)which is doing great job on Chloreserol. Wondering about any interactions or whether either of these contribute to side effects. M 55 4 years
5/23/2007
 1  Type II Was put on actos for type 2. Worked great for glucose levels. been on for 2 years, 75lbs weight gain, alot of edema/puffiness in belly. Having panic attacks at night due to feeling of "loss of breath" Afraid I have hit congestive heart failure. but have not. This medication can play mind games. Its horrible, if your doctor gives it to you, hand it back and ask for byetta. Side effects are literally killer. Stay away from this. FDA needs to re evaluate this drug. M 26 2 years
5/23/2007
 3  Type 2 Well, been taking for 5 years now. Have had severe nervousness, shortness of breathe at times. Thought it was "anxiety" attacks. Never had them before and they still occur. Never thought it might be this drug but will talk to my Endo. about this again. He never related it to this drug but think he should. Swelling in feet and ankles. Decent job helping BS levels. First time I've read others who take this drug. Very concerned this drug is the problem. Have also gained a lot of weight since taking this drug. Never attributed that with Actos either. I remember taking Glucophage when I was diagnosed in 2001 but had to stop because of side-effects. M 45 5 years
5/21/2007
 4  Type 2 diabetes lethargy I have had no weight gain. I've actually lost about 8 lbs since I started taking this medication almost 3 weeks ago. I drastically changed my eating habits and am now excercising daily. My blood sugar has gone from an average of 280-300 to an average of 125-150. F 32 3 weeks
5/16/2007
 1  Dr. Recommended Weight gain. Belly fat. Just didn't feel that good. This is a follow up on my comments entered in April I did tell my doctor to take it himself. I should say my former doctor. My recent blood tests came back with the following results after stopping Actos for 3 months. Cholesterols 184. Hdl/Ldl ratio now 3.5 after being 4.8. Thanks to Red Yeast Rice and 500 mg Niacin daily. For the first time in years my A1C came in at 6.5 My new doctor is an Osteopathic Physician. He changed my BP medication to a generic. My former meds were tier 3 costing me 100 bucks a month. BP improving more every day and is under better control. I'm experiencing about a 25 percent reduction in my insulin requirements. Do not use Actos. M 70 85 days
5/10/2007
 2  Diabetes Type II Ankle swelling, tightness in chest, rapid weight gain (approx. 1# per day) My doctor put me on this because he thought Metformin was causing my bouts of diarrhea but I also have liver disease (cirrhosis from NASH) and I don't think this is helping my liver any. I've called and left a message that I'm stopping Actos and going back to the Metformin. F 56 3 weeks
5/8/2007

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