ACTOS Reviews (PIOGLITAZONE HYDROCHLORIDE)

Average Rating: 1.7 (361 Ratings)

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 Type: Rx Drug

  

ACTOS  (PIOGLITAZONE HYDROCHLORIDE):  Pioglitazone is a diabetes drug (thiazolidinedione-type, also called "glitazones") used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. It works by helping to restore your body's proper response to insulin, thereby lowering your blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Pioglitazone is used either alone or in combination with other diabetes medications (such as metformin or a sulfonylurea such as glyburide). Talk to your doctor about the risks and benefits of pioglitazone.   FDA Approval Date: 1999-07-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ACTOSCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Type II Diabetes Really bad muscle pain throughout body. Terrible pain in mouth, gums, tongue. Persistent headache. Sense of being bloated. The weight-gain issue is a huge problem for me. Won't increased weight be bad overall? I was working out but have not worked out for three days because of excruciating muscle pains. What's the point? F 57 5 days
1/14/2008
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 1  "Diabetes" (according to my doctor) Extreme muscle pains (legs, knees, shoulders), fatigue, unexplained weight gain, lethargy. Good thing that my drug-happy doc switched me from 8 mg Avandia to 45 mg Actos, or I never would have realized how these drugs were ruining my life. I had been suffering for two years on Avandia (without realizing that I was suffering side effects) because my doc thought that a 120 blood sugar reading was too high and switched to Actos due to concerns regarding heart damage. The aches and pains that I had experienced for two years suddenly got much worse and I put on 10 pounds in a month - I'm not overweight and previously my weight was very stable. Hungry and eating all the time. Felt terrible and had no energy. Thought that it was all from aging. Stopped Actos four weeks ago after reading this website and FELT IMMEDIATE RELIEF. When I woke up the next morning, I thought that I was 10 years younger. Went to work on diet and exercise and dropped 20 pounds. Blood sugar is at 90. NO PAINS, LOTS OF ENERGY. This drug can have extremely powerful side effects. M 58 1 months
1/14/2008
 2  diabetes Swelling in my left knee and legs after the 3rd day. Extremely emotional crying. Feel puffy and lethargic. I am not going to take this drug anymore. F 37 4 days
1/9/2008
 1  type II diabetes gained 30 lbs in 3 months. severe muscle and joint aches. after reading all of these side effects and gaining so much weight in such a short amount of time, i'm not going to take actos anymore. F 55 3 months
12/23/2007
 1  Type II Diabetes Extreme lethargy M 63 5 days
12/19/2007
 1  diabetes 2 excessive weight gain...50 lbs in 1 yr. what more is there to say? after a gain of 50 lbs? F 63 1 years
12/16/2007
 5  Glucose levels of 275 -290 morning Weight gain of about 10 pounds Diabetes was diagnosed about 20 year’s ago. I could not tolerate Metformin and was on 45 mg Actos and 5mg Glyburide up to 3 year’s ago. I ran around 95 Glucose daily, no matter what I ate. I lost some weight on a diet and the doc took me off the Actos. That was my demise. I tried for 3 years to get him to put me back on, and he would only put me on Avandia. Avandia didn’t work at all for me and besides taking max. of Avandia (8 mg daily) I was also taking max of Glyburide (20 mg a day). My numbers were 275 – 290 daily. The doc then ALSO put me on insulin, saying he had no choice, as “he said” my body apparently was worn out with the years of taking diabetic med's. It took the act of the VA switching from Avandia to Actos to get me back on Actos. No matter what the doc’s think about both those med's being extremely similar, Actos is my wonder drug. I dropped the insulin within 3 weeks and am just taking the 45 mg of Actos and 10 mg of M 67 20 years
12/14/2007
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 4  Lyme Disease 9 lb weight gain, on 30mg. My doctor prescribed Actose to help with flaring up I was having in my Lyme Disease (it's an off-label indication). Initially it was GREAT and really helped; it actually increased my quality of life substantially. I had no side effects for 10 months, but then in the past 3 months, I've gained 9 lbs. I've always had a stable weight and exercise regularly, eat healthily, etc. It's been confusing. My dr. suggested I try going off, it's been 3 days only. I'm working really hard at the gym. I hope I can get the weight off. I just don't feel as comfortable in my body. Hopefully my flaring up won't get worse again being off the medication. Thanks! F 30 1 years
12/7/2007
 1  Type II Diabetes major dizziness, fatigue, headaches sore tongue(feels like I have canker sores all over the sides of my tongue)Dry mouth, weird taste in my mouth. Just started taking Actos 15 mg's once a day added to my metformin and byetta and my numbers are actually slowing going up. First reading this am was 425 Does it take a while for this to work and did anyone else see a rise in their numbers? Thinking about just going off of this before the inevitable weight gain starts along with all the other symptoms. Does anything work for diabetes that doesn't have major side effects? F 48 7 days
12/6/2007
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 1  Type II diabetes Gained 16 lbs in 2 months, shortness of breath, fluid retention, tired I rarely get drug side effects so was surprised Actos hit me so hard. I'll be changing to Byetta next week after my training appt. Funny thing was Actos didn't even improve my A1c. F 61 2 months
12/5/2007
 1  Type II Diabetes Headaches, fatigue, loss of appetite, cough, blurry vision Added to my Glyburide and Metformin because of poor blood sugar control. After reading the side effects experiences on this site, I'm done with it. M 54 10 days
11/27/2007
 4  Diabetes Type II No weight gain, lethargy upto some extent M 33 2 years
11/24/2007
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 1  Type 2 Diabetes Severe edema in stomach, groin, legs and feet; put on 36 lbs. in 2 months; shortness of breath; lethargy; stopped taking Actos 2 weeks ago and still gaining weight and miserable! Anyone out there lose the weight after going off of Actos? How did your doctor treat the side effects, specifically with regard to fluid retention? M 2 months
11/22/2007
 1  type II steady weight gain of about 20 lbs over 9 months I even started going to the gym & got up to a 14 minute mile!! Unable to lose any weight with excercise or diet. sugars seem to be the same regardless of meds. F 46 1 years
11/13/2007
 4  Diabetes - Type 2 NONE- I've lost 22 pounds in 10 weeks and my HA1C has gone from 11.9 to 7.1. Daily medication is Actos 30MG/Meformin 2000MG. Sounds like I'm the lucky one- NO weight gain, NO oedema, NO breathing or blood pressure issues. At least yet! Diagnosed 15Aug2007. Fasting BS 425 with an HA1C of 11.9. Began working out 45 minutes X 2 daily and limiting carbs to 70 per day. My average BS is now 115 and my H1AC as of 26Oct2007 was down to 7.1. M 52 10 weeks
11/1/2007
 3  type 2 weight gain taking 15 mg hopefully next time i see dr she'll take me off theactos been taking byetta still taking metformin and glybride F 37 5 days
10/23/2007
 1  Type 2 diabetes weight gain over a period of years of almost 100 LB. bloating and edema. joint pain. weight gain got worse as dosage increased. The more weight I gained, the more the doctor prescribed. I finally quit taking it 3 months ago against my endo's advice. I told her when I went back last week for checkup that I had stopped taking it and refused to take it anymore. I have been using Byetta( which she prescribed) and taking Cinnamon supplements. Was she surprised when I had lost 15 LB and and my A1c was 6.0. She did not even prescribe any replacement meds for me. Said I was doing an excellent job of controlling my sugar without it. I wouldn't take Actos again for any amount of money. F 54 7 years
9/29/2007
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 1  Type 2 Diabetes Fatigue, Rapid Weight Gain I have been taking Actos 45mg and Metformin 500mg for a almost a year now. Although it did help to lower my blood sugar somewhat, I have gained about 40 pounds and feel like crap all the time. I know the problem is the Actos I'm taking because I was diagnosed with Diabetes 9 years ago and was actually losing weight until I started taking this medication. F 31 12 months
9/23/2007
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 2  Type II Diabetes 40 lb weight gain in spite of closely monitored diet.Lethargic.All my doctor can say is lift weights, run, exercise. Blood Sugars have been great. Taken 2 A1C's both 6.5. However BP went up last 3 months and cholestrol jumped 85 points.This is not a well researched drug in my opinion and dangerous M 56 7 months
9/21/2007
 2  PCOS possible weight gain, shortness of breath, lethargy Began ACTOS when I could not tolerate Metformin. Initially with 30 mg, AF returned for 2 cycles, but then stopped again. I never felt that the Actos did anything but continued to take it on advice of endocrinologist. Later added Metformin XR. Gradual wt gain over 4 years possibly due to Actos or SSRI also taking. Now planning on d/c Actos because of "black box" warnings in this class of medicine. F 28 4 years
9/15/2007

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