WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  my mind was go too fasg I only have a problem when I don't take them. I can tell if I forget to take them, then I cry and start feeling' crazy and no one can talk to me. F 55 6 years
150 1X day
2/22/2015
 4  Depression and migraines Started out ok. I have started crying every day. I'm not sure if this is something that anyone else is experiencing. I do know I have to take the Wellbutrin XL brand name. Not the generic. The generic doesn't work for me. F 60 6 years
300mg 1X day
4/6/2021
Email
 4  Chronic/severe Depression tremmors, a little anxiety, weight loss (yay), dizzyness I switched to wellburtin after being on paxil for about 3 or 4 years. The paxil started to become ineffective, and i gained about 35 lbs. on it, not fun for a teenager. The wellbutrin took a while to get into, my dr started me out really slow, and the tremmors were pretty bad at first. But if anyone is just starting out on this drug i say give it at least 2 months and expect that the side effects will stick around until you've reached the dose your going to stay at. But unless you are having major debilitating side effects, at least give it a change, it'll get better. One thing i want to note, they switched me to the generic buprobion or whatever when it finally came out...it was a bad point in my life anyway were is was struggling with a lot of family stuff, and i just thought my depression was getting worse, and the anxiety was worse, etc. My dr. switched me back to brand name, and I started feeling better again, more energy, happier, dealing with things a lot better, less anger, ect F 25 6 years
3/5/2008
 3  Depressio Exhaustion while exercising, nervousness around people, insecurity for no reason, rapid heart beat. M 40 6 years
150mg
11/12/2013
Email
 5  Depression Initially experienced dry mouth, restlessness, a little anxious, headache. Eventually the side effects went away, but cannot take Wellbutrin without also taking Lexapro-on just Wellbutrin, I get too anxious I have taken Lexapro for 10 years and Wellbutrin for about 7. I went off Well Turin for a year, but just started back to help with my lack of energy. Helps keep my energy up and suppresses appetite somewhat -which is good because The one side effect I have with Lexapro is increased appetite. F 51 7 years
150-300mg
12/11/2014
 5  Depression Anxiety, Increased Heart Rate, & Shakiness. Wellbutrin has done wonders for my depression. However, if you are an extremely anxious person, it may make your anxiety worse. It can make you shaky (specifically the immediate release version), but the XL didn't make me too shaky. It definitely helps with libido and did not cause any sexual side effects for me. Honestly the only downside is increased anxiety, but I would rather deal with anxiety than depression. If SSRIs don't work for you, I highly recommend trying Wellbutrin. F 24 7 years
300 mg 1X day
2/18/2022
 5  depression none after the first few months I have been taking wellbutrin for 7 years. This drug saved my life. F 40 7 years
9/19/2007
 5  depression I added this to my SSRI, Zoloft, and it worked really well. That was my "magic cocktail" for YEARS. I recently switched from Zoloft to Remeron to avoid the sexual side effects, but am still on Wellbutrin XL. No complaints F 27 7 years
300 mg 1X day
11/30/2010
 4  smoking cessation, depression Intense sex drive, rage, energy, zyban allergy. I told my doctor i wanted this need for smoking cessation, continued getting the rx for depression. I was using depo-provera and had no libido. Wellbutrin in the regular 300mg dose was making me a sex maniac, giving me a rash, causing my eyes to water, making me get mad about small things and nearly homicidal about big things. I cut my own dose in half and the side effects aren't really noticeable to me now. F 42 7 years
150 mg
5/28/2012
 4  Severe depression Grand mal seizures, short-term memory loss, acne It made me want to dance in the street. I had some weird things happen, like suddenly forgetting how to drive (I had to pull over for about 30 minutes)... but I had my life back, so I didn't much care. Within the first year of going on it, I had a grand mal seizure, but the ER doctors were hesitant to call it a seizure despite multiple eyewitnesses. In March 2016, I had another seizure -- and another, and another, three in one day. I was diagnosed with epilepsy and spent three days in the hospital. They took me off of the Wellbutrin cold turkey, which I guess was necessary but it resulted in a severe depression relapse and acute suicidal ideation. The official judgment from my neurologist is that Wellbutrin does not cause seizures but it lowers seizure threshold, so it increases the likelihood of a seizure for people who are already vulnerable. It's worth stating I NEVER had a seizure when I wasn't taking this drug. I have since found a different miracle drug - the anti-convulsant and mood stabilizer, Lamictal. Anyway, I guess Wellbutrin messed with me neurologically in a huge way and I didn't even understand the full implications of it until after I was off of it. I am back to a level of mental acuity I haven't felt in years. Also, my skin cleared up immediately when I went off the Wellbutrin. Just be careful. F 33 7 years
300 1X day
9/26/2016
Email
 4  Severe depression Grand mal seizures, short-term memory loss, acne It made me want to dance in the street. I had some weird things happen, like suddenly forgetting how to drive (I had to pull over for about 30 minutes)... but I had my life back, so I didn't much care. Within the first year of going on it, I had a grand mal seizure, but the ER doctors were hesitant to call it a seizure despite multiple eyewitnesses. In March 2016, I had another seizure -- and another, and another, three in one day. I was diagnosed with epilepsy and spent three days in the hospital. They took me off of the Wellbutrin cold turkey, which I guess was necessary but it resulted in a severe depression relapse and acute suicidal ideation. The official judgment from my neurologist is that Wellbutrin does not cause seizures but it lowers seizure threshold, so it increases the likelihood of a seizure for people who are already vulnerable. It's worth stating I NEVER had a seizure when I wasn't taking this drug. I have since found a different miracle drug - the anti-convulsant and mood stabilizer, Lamictal. Anyway, I guess Wellbutrin messed with me neurologically in a huge way and I didn't even understand the full implications of it until after I was off of it. I am back to a level of mental acuity I haven't felt in years. Also, my skin cleared up immediately when I went off the Wellbutrin. Just be careful. F 33 7 years
300 1X day
9/26/2016
Email
 3  Depression(stress/cfs/fms) (namebrand)2 150mg wellbutrin xl iAM for yrs, but with recent new order nervousness, sleeplessness, muscular burning/clenching spasms, sob and gastro complaints similar history with generics tried. . have appt for dr to evaluate first available F 54 7 years
150mg 2X day
6/11/2013
Email
 5  depression I haven't had any side effects from Wellbutrin or the generic alternative. When I first began the medication, I was severely depressed most days of a given month. I noticed improvement very soon after beginning the med. Not all days are depression free, but most of them are. And the magnitude of depression is not what it once was either. So I'm happy with the medication. My only concern is long term usage. I've been on a long time (I said 8 years, but I think it is much more -- like 12-ish). My doctor has not informed me of any long term complications of the medication, so I'm still on it. Plus I'm post menopausal now (wasn't not when I first started), so it may be helping with menopausal-based depression as well. F 51 8 years
300 1X day
7/13/2010
 5  depression(death of spouse) I was sent the generic version one year ago severe symptoms emerged. I reported this to my Doctor and she prescribed NO substitions. I was symptom free within one week of the switch!! this needs to be shared with patients taking the generic. I thought I was loosing my mind when in fact there is a different response to these two versions. F 66 8 years
11/16/2007
 5  Depression Modest weight loss, renewed interest in sex This drug has truly saved my life more than once. I cannot tolerate SSRIs or MAOIs, and Wellbutrin literally gets me out of bed in the morning. It has brought back motivation I had lost due to depression, and I am able to view problems more realistically. Have never had a thought of suicide while on this medicine, because it lifts me up so much: it makes me ME again. No other antidepressant has been able to match Wellbutrin XL's lifesaving effects. My doctor mentioned that I should never try the generic because studies have shown that it doesn't work as well as the name brand, so now that the generic is often substituted in American pharmacies I buy this from a pharmacy in Canada. Canadian cost is 1/3 the price of how much I pay with insurance in the US! Every once in a while when the medication at 300mg is too much, my doctor reduces the amount to 150mg and vice versa if I'm needing more medication. I could not live without this medicine, and I truly believe that I am still alive t F 27 8 years
5/11/2008
 5  Depression I had insomnia when I first began taking it 8 years ago, but that went away in a few weeks. I've tried Celexa, Lexapro- both caused anorgasmia. Zoloft and Prozac made me too sleepy. Wellbutrin XL has been wonderful! It has not lowered my sex drive, it has not caused anorgasmia, and I lost weight when I first began taking it. I can tell when I've missed my dosage and so can everyone around me! I take 450mg every morning and I am happy and energized! F 48 8 years
3/3/2008
 5  Adult ADD, Clinical Depression Dry Mouth Almost immediately after starting this medication I experienced a lifting of the fog that had covered my mind for my entire life.It gives me energy,a relief from depressive thoughts and the ability to focus. What a godsend! F 47 8 years
8/2/2005
 5  depression / bi-polar The first month or so of taking wellbutrin SR (300mg) made me experience dry mouth, insomnia, loss of appitite and a strange feeling every time I swallowed. It was like the timing of my swallowing was off and each time I swallowed, I swallowed air. Obviously some bloating accompanied it. After the initial side effects went away, I experienced great relief from my depression. However I was more irratable than ever. It was paired with Depakote (made my hair fall out) and then Tegretol. That second combination has made my life so much better for the last 8 years. I still have dry mouth and my eyes feel dry often, and sitting in a windy area for an extended time will give me a headache. But that discomfort is so worth the stability and patience I now have. F 30 8 years
7/15/2005
 5  Depression Severe side effects while adjusting including dizziness, dry mouth, trembling, headaches, insomnia and agitation Severe side effects while adjusting including dizziness, dry mouth, trembling, headaches, insomnia and agitation. Was able to back off and start over at a very low dose and gradually increase over 8 weeks and that seemed to help with some of the side effects. These problems diminished over time and though it was very difficult in the beginning, it seems to be the miracle drug for me. I have been consistently stable for 8 years on this medication and will most likely remain on it. F 37 8 years
12/8/2009
Email
 5  Migraines and depression Weight Loss. Felt a little "high" at first but nothing too extreme. Weight loss at first but only about 15 pounds. I finally felt happy and I actually wanted to get up in the morning and do something. Didn't help migraines much but greatly improved my depression. Recently diagnosed with Fibromyalgia and tried to increase does to 450mg (up from 300mg) and it caused extreme anxiety and panic attacks so I decreased back to 300mg and I feel fine again. F 43 8 years
9/20/2008

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