WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Depression, anxiety Tinnitus, forgetfulness, headaches, alcohol intolerance (after one occasional beer or glass of wine I seriously felt like someone drugged me), decreased appetite, frequent bouts of insomnia, dizziness (and just in the last four months: unexplained sadness, irritability/anger, high "highs" and low "lows", increased anxiety, "corner-of-the-eye" type hallucinations) I had been on Paxil for 6 years for depression, anxiety and OCD. After weaning off of that with surprising success, I had been "drug free" with few symptoms for the next two years when one day out of the blue, the depression came back with a vengeance. After the horrible side-effects I experienced with Paxil (including a 60-lb weight gain), I was scared to go on another SSRI so my doctor put me on Wellbutrin XL (150 mg). For the first two years, I felt like a new person. This "miracle drug" really was a God-send! My husband said he was happy to have me "back" and the initial side-effects were a small price to pay for feeling like myself again. I also lost about 10 lbs. Over the past four months, however, I've felt more side-effects than benefits. The tinnitus is so bad at times, it's almost unbearable. My anxiety has come back and is worse than it's been in years. I cry all the time, mostly over nothing. The tiniest things get under my skin. I F 32 3 years
2/16/2007
 4  depression decreased appetite, at first/ weight loss/ crying more than normal, for several months/ increased sex drive/ ringing in ears. All have been worth it to get the benefits. I took Wellbutrin for almost 2 years. I've taken Wellbutrin XL 300mg for about 6 months. In general, they seem the same. The most significant difference is during what would be PMS. I had a very hard time with PMS for about 10 years before I started using Wellbutrin. I was extremely irritable, everything upset me, and my skin tingled. I felt like I just wanted to crawl out of my skin. It was terrible. Those things don't happen anymore. Now the only PMS symptoms are just normal bloating and cramps. When I first started Wellbutrin XL, I seemed to cry more than normal, but that's pretty much gone away. I've also lost a lot of weight. I stopped taking it for 2 weeks, but had to start back. I experience ALL of the PMS symptoms described earlier. I hadn't done that in over 2 years. F 42 3 years
2/22/2007
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 4  depression decreased appetite, at first/ weight loss/ increased sex drive/ ringing in ears. All have been worth it to get the benefits. I took Wellbutrin for almost 2 years. I've taken Wellbutrin XL 300mg for about 6 months. In general, they seem the same. The most significant difference is during what would be PMS. I had a very hard time with PMS for about 10 years before I started using Wellbutrin. I was extremely irritable, everything upset me, and my skin tingled. I felt like I just wanted to crawl out of my skin. It was terrible. Those things don't happen anymore. Now the only PMS symptoms are just normal bloating and cramps. When I first started Wellbutrin XL, I seemed to cry more than normal, but that's pretty much gone away. I've also lost a lot of weight. I stopped taking it for 2 weeks, but had to start back. I experience ALL of the PMS symptoms described earlier. I hadn't done that in over 2 years. F 42 3 years
2/22/2007
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 4  depression Hypertension I never had a problem with my blood pressure until I switched to XL, and have switched back to SR. BP immediately dropped back to normal. F 33 3 years
450 mg 1X day
6/30/2010
 3  Depression/Aniexty Dry mouth & tremors Wellbutrin worked well for me after the side effects went away after a month or so. M 35 3 years
300mg 1X day
8/27/2010
 3  Depression Hair loss, memory loss I loved this medication for making me feel "normal" again but for 3 years I couldn't figure out why my hair had thinned by over 50%. After recently doing some internet research I found tons of information on people who have lost hair due to Wellbutrin and so decided to gradually wean myself off of it. I've gained 10lbs in the month I've been off it, am excessively tired and find myself less happy in general - but I don't want to continue to lose more hair. It's very upsetting because when I first started losing my hair I checked the side effects of Wellbutrin and it's not listed as one so I assumed it was from something else. It's frustrating that the manufacturer isn't required to list it as a side effect when clearly so many people are suffering from hair loss due to this medication. F 34 3 years
600 1X day
7/8/2012
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Patient History
 3  Depression/Anxiety Constipation with increased dosage, trouble with sinuses (began same time as constipation): Both occured after an increase to 400mg/day, and has continued for over a year. Dr. says no way the drug is giving me constipation. I also take Celexa. Wellbutrin gives me multiple orgasms. F 33 3 years
2/19/2006
 3  depression decreased appetite, at first, and weight loss I took Wellbutrin for almost 2 years. I've taken Wellbutrin XL 300mg for about 6 months. In general, they seem the same. The most significant difference is during what would be PMS. I had a very hard time with PMS for about 10 years before I started using Wellbutrin. I was extremely irritable, everything upset me, and my skin tingled. I felt like I just wanted to crawl out of my skin. It was terrible. Those things don't happen anymore. Now the only PMS symptoms are just normal bloating and cramps. When I first started Wellbutrin XL, I seemed to cry more than normal, but that's pretty much gone away. I've also lost a lot of weight. I stopped taking it for 2 weeks, but had to start back. I experience ALL of the PMS symptoms described earlier. I hadn't done that in over 2 years. F 42 3 years
2/22/2007
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 3  bi-polar Loss of sex drive, weight gain, dry mouth F 29 3 years
8/9/2007
 3  depression Irritability, occassional anxiety. I was switched from generic bupropion SR to Wellbutrin XL. There is no difference in efficacy. For those of you for which money is a concern or you don't have insurance, stick to the generic bupropion SR. I wouldn't particularly recommend Wellbutrin for those who are high-strung or have problems with anger. M 24 3 years
5/9/2007
 3  Major Depression Excellent stimulatory antidepressant. Enhanced libido, increased energy, assertiveness. I'd take it forever if it wasn't for the hair loss and weight loss. F 49 3 years
4/29/2008
 3  PTSD - major depression Slight humming or ringing in my ears Vision problems Wellbutrin is about the only prescription drug I could tolerate without numerous side effects. I can't use SSRI's etc. Lately though my eyesight is becoming increasingly troublesome. I have developed cataracts and of course my age plays a part in this too. But I now have blurred vision, sometimes double vision and pain in my left eye. My blood pressure has also increased. I also take Xanax and Ambien as needed. Have no idea what to try next but the vision problems are really scaring me. F 66 3 years
150 MG 1X day
12/7/2015
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 2  fatigue from Effexor, depression the constipation is ridiculous, pretty much never go to the bathroom anymore, if I skip wellbutrin for 2 days it all returns to normal, also makes me very nervous with a burning sensation in my chest gradually weaning off it... but it takes a long time F 26 3 years
7/29/2009
 2  Bipolar type 2 Loss of appetite, cycling. I'm currently on 150mg and receiving no benefit. On a higher dose, I can't eat and my mood starts cycling. F 24 3 years
4/3/2009
 2  Depression Shortness of breath, night sweats, excessive sweating during the day, tremors, elevated heart rate. I had to stop taking Wellbutrin after 2 or 3 years because the sweating, shortness of breath, and tremors got increasingly worse. It worked well on my mood though. F 28 3 years
5/9/2005
 1  Depression Angry and Hostile! I felt like I was going to explode and I felt like a hothead and control freak. I have been taking lexapro for 10 days and I feel sane again M 45 3 years
6/6/2008
 5  major depression disorder + anxiety Weight loss, decrease in appetite, high sex drive, ability to wake up easily (was always a problem for me), hand "intention" tremors at 300mg, tinnitus at 300mg, I recommend this med!! I am taking WXL 150mg 1x daily. could not tolerate XL 300mg dosage. formerly on original Wellbutrin and it made me unable to sleep and incredibly MEAN! Do not have these problems with WXL. caffiene makes me extra-jittery unlike before and it has not stopped my nightmares. I have taken nearly every SSRI, etc, out there and this is the only one I can take. For any episodes of depression, I have added a 12.5mg dose Zoloft for 2-4 weeks. This is menstrual or seasonally-related for me and the Zoloft readjusts everything properly and I'm back to normal on just the WXL. If I miss a dose, I do get the "cry" phase, so I just don't miss any! F 28 3.5 years
2/4/2008
 5  Chonic depression Initial side effects: a weird kind of vertigo. Longer term: increased appearance of OCD-type behavior, insomnia, irritability. Started on SR, moved to XL shortly after it hit the market. The After years of prozac/xoloft/counseling, I now feel about 85-95%of normal - able to concentrate, follow-thru, have energy. Loss of libido that came w/SSRIs has not really returned, altho I have had occasional moments, but ability to reach orgasm has returned. F 51 3.5 years
7/22/2005
 5  anxiety and depression Insomnia for the first month. Over 300mg I had a period all month long but lowering dose to 300 fixed that. A little dry mouth at first. All the bad side effects went away after a month or so. I lost about 40lb, probably because I had so much energy. It is a life-saver. I tried 5 other anti-depressents and was about to give up. I had forgotten what it felt like to be normal and wellbutrin XL helped. It is even worth the $1,000 out of pocket I have to each year for it. Try it before you give up. It also helps with my RLS symptoms. F 27 3.5 years
6/28/2006
 5  Depression The only side effect is getting my sex drive back that I lost while taking Zoloft and a couple of others. I take Buproprion HCL XL. If you are feeling better, and want to get off of the medication, take it very slowly. I was feeling better, and my doctor weened me off what he thought was slowly, but incredible depression started. Worst of my life. I am back on it and feeling okay again. Notice I didn't say great. I just feel normal. (Which is good) Also, Budeprion made by the company Teva is NOT the same. Pharmacy gave it to me and depression and anxiety kicked in immediately. Got back on Buproprion, and again, just feel normal. M 34 4 years
300 mg xl 1X day
11/8/2010

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