WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  generic 2days and I feel much worse. I am going to get the real thing instead of generic. It's made me smoke more. M 47 2 days
300 1X day
11/2/2010
 1  To Stop Smoking Fisrt day 150mgs twice 8hrs apart, 2nd 150mg. Dizzy Spells,nausea and vomitting, Major anxiety attack lasted 2 hours, uncontrolable stuttering and ticks, managed these symptons with 1mg xanax, tick and stuttering recurred the next day, probably as the xanax left my systom. This may not be the case for everyone, it seem that my body chemistry and welbutrin do not jive, also I overdosed my self, it turns out that I should have started 150mg per day for the first 3 days before upping the dose to 2 times a day. Waiting to see how long this lasts. M 28 2 days
1/31/2007
 1  Smoking Cessation HORRIBLE HIVES!!!!!!!! I took my first pill on a Wednesday at 4:00 pm. I took the second pill on Thursday at 4:00 pm. Woke up at 3:00 am on Friday with itchy toes, then ankles. By 11:00 am I was in serious trouble, with horrible hives everywhere. I suffered tremendously. I never knew ANYTHING could ITCH SO BAD!!! I stopped the meds per my doctor and took Benadryl to no avail. I had hives on my feet, legs (horrible on my inner thighs), belly, butt, chest, scalp, face, swollen ears, etc. I finally took some Prednisone that my dog had (steroids) and it began to fade. Six days later, I am okay with just a slight redness on my face. It was hell. My advice is to immediately take steroids if you begin to get hives. I may try Chantix next but I'll wait until I get over this trauma. F 53 2 days
9/17/2009
 1  fatigue, depression jittery, hyperactive, cold sweat, panic attack, rage, insomnia, loss of appetite, low blood sugar, paranoia, thoughts of committing violence, headache I took Bupropion XL made by Teva, generic for Wellbutrin XL. 150 mg in the morning with food. It took away my depression and replaced it with desperation as I tried to survive the side effects. Absolutely intolerable. By day 2 I felt much worse than I had when depressed. I will not take this ever again. F 42 2 days
6/13/2009
 1  A 91 year old senior is taking it It causes him to drink alcohol M 91 2 days
150
9/28/2014
Email
 4  switching from zoloft / for anxiety loss of appetite. very emotional the 1st week. more energy. 2nd week went from 150mg to 300mg. I'm almost @ 3 weeks and have lost 8.5 pounds - great for trying to get the 15 pounds of baby weight off. F 34 2.5 days
9/12/2007
 5  Depression/ and severe anxiety Headaches, nauseau, complete loss of appetite. Wow, within hours I felt clearheaded and motivated and the lethargy that Zoloft has caused dissapated immediately! I'm on 50mgs of Zoloft and 150mgs of WXL - I will wean off the Zoloft slowly and just be on WXL. I have lost 2 pounds in 3 days but I gained 55lbs on Zoloft. I was afraid of insomnia but I exercise very hard for one hour daily so insomnia is not an issue. Also, it would be interesting to know how many people taper off of an SSRI and go onto Wellbutrin. Withdrawal from those bad boys can major rage/agitation/anxiety so maybe Wellbutrin is not always to blame. F 33 3 days
5/26/2006
 5  SAD I'm on the 150 mg SAD dose and won't be going up to 300. Headache and flu symptoms the first night. Vivid dreams. Super increased energy and focus on whatever I'm doing. Paradoxically this focus produces a kind of "out of touch" feeling. House is VERY clean. Marked appetite decrease, a sense that I've had enough so I should stop eating, definitely a plus when SAD mkes you feel ravenous and CRAVE fatty, carby foods. Does the kind of disconnected feeling diminish? If it does, I think I'll like this medication. I was not severely depressed, more SAD but long term stress had produced a flat feeling that sometimes shifted over to depression. I have definitely noticed since starting the medication that I have a super intense focus on whatever I'm doing. This is good, but I'd prefer if it wasn't so intense. Does the focus balance itself out in time? Does the sense of being diconnected go away? I'd like to feel joy again. Don't want the "good" emotions dulled, just get rid of the physical depression. F 53 3 days
1/23/2007
 5  Major Depression nervousness, shaky hands, increased heart rate Suggestions? Today is my third day on Wellbutrin XL 300mg. This is the first antidepressant I've ever taken. I'm not sure what to expect. Will I wake up one morning and want to actually get out of bed? I don't feel any differently than I did a week ago. (Rating 5 -- hope it will work) F 28 3 days
3/9/2007
 5  BiPolar-Manic- MS I went from NO energy what so ever to being in a race car. I can not sleep and when I do finally fall asleep I wake 2-3 times per night in sweat from my head to my toes and my bed drenched. My mouth is terribly dry. I am just glad to have my energy back but it sucks not being able to sleep. I have been VERY ill for the last 6 months and due to being sick it has started to affect me negativly in a emotional way. I am on the generic form of 150mg per day. If anyone knows of anything else for me to try please send me a email, I am willing to try ANYTHING. I am only on my 3rd day but we will see what goes from here. Keep your fingers crossed :) F 22 3 days
1/7/2006
Email
 5  depression Tingly feeling all over body, nausea, periods of overwhelming sadness and crying, dizziness, light headedness, chills (could be from going off Cymbalta?) I took the cue of another and gave this a 5 so it would be posted at the top, I don't really know how I would rate it just yet. I just started taking this (150mg/day) 3 days ago. I stopped Cymbalta 3 days ago after taking it for a 1.5 months for chronic back pain (unknown cause) and depression related to pain. To put it bluntly, I AM A MESS! I feel like crap... I have been having major nausea, chills (flu-like) and a tingly sensation pretty much all over my body. Oh, and I am tired and crying for pretty much no reason. Did I mention the lightheadedness and dizziness? What is going on? I don't know if this is from going off the Cymbalta (on 40mg/day) or if it is from going on the Wellbutrin XL. Spoke with my GP today and she said feeling "like death" (my words) was "normal" (her words). What does that mean? I hate this. I am so sad and feel like a loser, and feel sorry for my poor husband who has no idea why I am crying or feeling awful! Has anyone else expe F 28 3 days
9/25/2006
Email
 5  Depression Somewhat uncomfortable amount of energy I was taking lexapro for 2 weeks to treat newly diagnosed depression (though i've been depressed for 2 years). the lexapro was great but my sex drive was completely annihilated and that made me feel a little inhuman, plus i felt somewhat emotionally numb. so I switched to bupropion & my ability to orgasm was back within the first day of stopping lex. i have a LOT of energy and i have NEVER been an energetic person, even in childhood. i have kind of a pothead demeanor (or maybe I'm just a pothead) but these past three days I've had crazy energy and everyone is noticing which is actually making me a little uncomfortable. but I like it because I feel up to doing things for the first time in a LONG time and have the energy to actually follow through on plans and enjoy them. yesterday was out of the house from 12-9PM in DC walking around and only felt tired (in a good way) around 10 PM. This drug is a comparable to adderrall in that you can focus on a task for a while and not be thinking about anything else. no trouble sleeping since I take it in the morning. However -- last night around 3 AM (went to bed around midnight) I woke up feeling like I might throw up - not nauseous, just had a feeling that might happen - and was confused for about 5 minutes, then fell asleep very quickly after realizing nothing was going to happen. In my [[inexpert]] opinion, you should try this drug for depression if you're already low energy, have a low sex drive, and aren't prone to anxiety attac F 22 3 days
150 mg 1X day
4/11/2010
 4  depression, anxiety, bi-polar weight loss, decrease in appitite, high energy i took wellbutrin SR a year ago for about 4 months and it made me gain 10 pounds ( which isn't a good thing considering i'm only 5 foot ) and i would always have really bad migranes and stomachaches. once i heard about XL i was so excited to try it, because without those side effects from SR i would have kept taking it. i've been taking XL for three days now and i've lost 4 pounds and i've never been happier. i feel like i have a better outlook on things and i'm laughing more. so i would for sure choose XL for SR. F 18 3 days
9/6/2005
 4  Depression/Anxiety Feeling wired up. A little sleepless. Dry Mouth I would say I'm now suffering Superman syndrome. I feel a little to talkative and am lacking a filter at times w/ my sarcasm. This stuff worked almost immediately and my anxiety is way down. I had been waking up most mornings in a bit of a fog w/ the weight of the world landing on me. I'm definitely more productive at work and find myself procrastinating less. I'd had a habit of feeling a little sad at times during the day and that is gone. So is some of the negative threads of thought that were present t/o the day. M 33 3 days
12/26/2005
 4  depressed sleep interruptions, tiredness after 4pm I was on Lexapro for 2 month, gained a lot of weight. It made me feel lethargic. Wellbutrin XL 150mg daily helped but not completely. I am still spacey sometimes. No effect on my appetite at all. I am still taking 5mg of Lexapro daily. Could that be the reason for not loosing any weight? Or I should take 300mg? Thank you. F 48 3 days
3/11/2007
 4  Major Depression spaced out feeling, diarrhea, intense anxiety, increase libido Have only been on WB XL 3 days. The depression is alot better but i'm having bad anxiety. I understand this will go away in 2 weeks or so. So I'll wait it out. The diarrhea went away after the 2nd day; I M 3 days
7/23/2005
 4  Depression/Lack of motivation Made cigarettes taste gross after a few days, although did not quit; after two glasses of wine, I felt like I had taken a sleeping people -- was in a total haze. Took WBXL for depression and general lack of motivation as a law student my first year and felt happier after 3 months on it. After that point, I discontinued use for over a year, and have begun using it again due to similar feelings of depression and lack of motivation. F 25 3 days
10/9/2007
 4  flat mood, fatigue, no libido increase in sexual thoughts, more cheerful, more easily aroused, sleep much better I took wellbutrin before and had many positive side effects, but was way too quick to anger. When I went off it I lost libido again, and started to have the flat mood return. I tried cutting a wellbutrin XL in to four pieces. I started with 1/4 of a 150 mg pill a day and got a buzz of energy on the first day, and marked increase in libido. I know that this "rush" of energy is a side effect, and that it will even out in a few days, but I was very surprised and happy to find I could get results with only 1/4 of the normal starting dose. I've tried the SR, and it made me nauseous and left a horrible taste in my mouth, so I was pleasantly surprised to find that even a cut XL tablet is easy to digest, with no nausea or aftertaste. When I went on wellbutrin the first time I felt like I was on speed for the first few days, but on 1/4 of the standard 150 mg starting dose I just felt a pleasant increase in energy. I think a very low dose will be "just right". My libido loss F 53 3 days
9/10/2007
 4  depression lack of sleep, trouble staying asleep,weight loss started on 150mg and my doc gradually brought me up to 450mg which was WAY to much.(I lost 60lbs in 1 1/2 months) Went down to 300mg and its working great. I feel like I can actually get out of bed in the morning. F 25 3 days
2/26/2008
Email
 4  always exhausted, moody, unhappy spacey, dull headache, tired eyes, jitters I have only been on XL for 3 days. I read everyone elses comments and they say that their first days where the best, well mine are not. I am happier though, not soo many thoughts running through my head. But then I feel like I am so tired, and jittery and spacing out. I hope that these are just the beginning and that I am the opposite of all these other people and that the side effects will diminish. I really feel better, but you know all meds do is take away one problem and leave you with another. It all comes down to what you can handle and what you want to be and not want to be!! I hope that it helps other people. I hope that it gets better for me!!! But so far it is good all over, give or take!!! F 23 3 days
5/4/2005

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