WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Depression w/ Lamictal, Bipolar Generic One: Lethargic for first few weeks, decreased appetite, upset stomach, complete taste for food change, headaches, weight loss Generic Two: Increased energy, positive mindset, some hair thinning and scalp irritation, a bit more anxiety, occasional tremors, further decreased appetite, weight loss, some trouble sleeping and vivid dreams, constipation This is the generic: In the beginning, I was always exhausted, sleepy, and irritable; I almost quit. My psychiatrist was confused and said that most experience just the opposite. I still wanted to give it a chance. Here is the story: When I first filled my prescription I was only given 2/3 of the pills prescribed b/c they were out of stock. When I went back to get the rest this was by a different brand but same generic. The difference was troublesome. While one was small, round and white(150mg), the other was about 3x its size, oblong, and yellow(also 150mg). When I ran out of the first generic(white pill) I started taking other(yellow). Immediate change. I wasn't tired, was +positive & +energy, mood swings gone, a bit more anxious; completely different from the 1st. The only thing in common was weight loss. I'm 5'2, used to weigh 121 & now weigh 111. 10 pounds in 6wks and I wasn't that big to start with. The loss of appetite & taste is crazy,I hate my fav. food & each day I crave & loathe something different. Overall, not a great drug, but I feel more balanced. This was the generic; based on all the reviews here the name brand sounds different & better. They began another trial recently, studying difference between the generic & name brand; look it up. Hoping generic gets smashed & companies will make an effective, more affordable option for wellbutrin. F 18 6 weeks
300 1X day
2/12/2010
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 2  mild depression, lethargy I am going off this drug after getting over the hump of almost all of the side effects because the memory loss is just too difficult for me. I only took XL150 for 6 weeks or so and muscle aches went almost away but it didn't really make me feel any happier. I did stop smoking though, very easily. F 37 6 weeks
7/1/2007
 2  Depression weight gain (6 lbs in 6 weeks), more anxious Dr. put me on Wellbutrin XL in addition to Paxil to help depression symptoms (Paxil works for me for anxiety, not much help for depression) and to help overcome sedating effect Paxil has on me. In 6 weeks being on this drug, I have gained 6 lbs. despite watching my diet and exercising as usual. This is going to sound crazy, but I swear this drug has caused cellulite, too. I have significantly more than when I started this drug, and significantly more than a 6 lb. weight gain should warrant. In addition, I have also become more anxious and obsessive. I DID feel significantly less tired and more hopeful, less depressed. But the extra anxiety and the weight gain has made me decide to quit this drug. PS. I've not had weight gain on any other drugs I've taken (Prozac, Effexor, Paxil, Cymbalta). F 30 6 weeks
8/4/2006
 2  anxiety and insomnia Muscle pain and joint stiffness. Ringing in ears. Feeling of "ready to jump out of skin". F 55 6 weeks
12/16/2008
 1  Major depression Grand mal seizures, extreme anger/rage, increased irritability, anxiety, loss of appetite, homicidal thoughts, increased suicidality, dry mouth, shaking, occasional nausea I started on 150 mg for a week and moved up to 300 mg without any problems. I was on this dose the longest. During this time I started experiencing all of the side effects I listed except for the seizures. People were telling me I was terrifyingly angry and violent all the time. The smallest things would set me off into an uncontrollable rage. As for suicidality, Wellbutrin actually helped some of the time while at others I hit extreme self-hating lows (extra energy = extra anger). I mentioned all of this to my psychiatrist, who suggested upping the dose even more to see if it was really the Wellbutrin that was causing my anger. I went up to the 450 mg dose, and 3 days later i was convulsing in the middle of math class from a huge seizure. I woke up very confused to a bunch of paramedics who took me to the hospital. After a long evaluation and lots of tests and scans, I was released and went back to school to pick up all my stuff. Once I got there I had another seizure (for b F 17 6 weeks
3/2/2006
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 1  Depression, fatigue, lack of motiva My depression has worsened. Unreal panic attacks, stayed in bed, zapped energy and motivation even more. M 49 6 weeks
3oo 1X day
9/20/2020
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 5  Depression / trouble focusing Headache the first couple days, after that, lesser appetite and trouble sleeping I'm not sure why everyone is bashing on the generic version, it's working for me. I've been depressed off and on for around 8 or 9 years and refused drugs until about a year ago when my life was failing and was seriously considering suicide. Tried a few antidepressants, but Bupropion XL saved my life. My doctor recommended this because I'm having trouble in college, but it mainly cured my depression. I'm reconnecting with some friends, getting out more, doing better in school, and better at work. The lesser appetite is minor for me and I need to lose some weight anyways. The insomnia makes some days hard because I'm sleepy, but overall it's worth it. F 21 7 weeks
1/11/2010
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 5  quit smoking Day 1 I felt like a zombie, but that went away. I still have trouble sleeping the whole night (6hrs) I usually wake a few times and I do have night sweats. I have actually had weight GAIN...and I was so looking forward to the side effect of losing! History: My doc gave me wellbutrin instead of Zyban because he said they were the exact same drug just marketed differently so the drug co. could keep track of it's usage (depression or quitting smoking) and he said that insurance usually pays more when given under the wellbutrine name. ---- It did it's job I quit smoking on day 4. At first I did still feel urges when I was angry or stressed, but that has all changed. I will never smoke again!!! :) F 28 7 weeks
7/23/2005
 3  anxiety and mild depression wellbutrin has been great about not having to many side effects but Im not sure if Im not taking enough or what but I still experience alot of anxiety also I have a constant urge to urinate and i dont have a uti and im 27 so i shouldnt be experiencing any bladder problems. Does anybody have any suggestions. F 27 7 weeks
11/12/2006
 3  Depression,anxiety,&to quit smoking Increased crying spells for first 4 or 5 weeks. Quick to anger and a lot of agitation and irritability. Dry mouth but not bad. Some insomnia. Binge eating, I'm not hungry but can't stop eating. I had tried taking wellbutrin in my early 20's and had to stop because of suicidal thoughts etc. however it has been about 15 years since then so I decided to give it another try. I did not start feeling any relief from depression (and seemed to have gotten worse) until about week 6. Now I don't feel so extremely low and sometimes have a good day. Honestly I have noticed no increase in energy but have noticed an increase in libido, which happened around week 3 or 4. I have cut down my smoking to a few cigarettes a day from over a pack for almost 18 yrs. However due to my agitation, irritability, and anger I am not quitting completely at this time. Interestingly I have severe menstrual cramps and it seems to help this ailment somewhat. When I was taking Prozac I always lost weight so it is interesting that on Wellbutrin XL (a drug known to help with weight loss) I am quickly gaining weight by binge eating. Perhaps it is due to cutting down on smoking, however most information I read led me to believe this wouldn't be much of an issue. I am hopeful that the Wellbutrin's effectiveness will continue to increase over the next month and that my anger and irritability will decrease, as well as my appetite. It is worth a try for anyone thinking of getting on it but keep in mind it can take several weeks of misery before you feel some relief, not always the case but something to keep in mind. This med seems to have helped an awful lot of people. F 37 7 weeks
300 mg 1X day
12/21/2012
 3  Depression, anxiety Started with 150 & 40 of Selexa. Dr weened from Selexa gradually and increased to 300. Since then, by mid afternoon everyday Im having some intense anxiety, sobbing and or angry . This is disappointing as I was sure this med was working so well. it's a scarey feeling though when im getting so anxious for no reason and so dispairingly sad and crying. F 44 7 weeks
300
4/22/2013
 2  Depression/ADHD HORRIBLE HEADACHES. Couldn't really do much of anything and was a contribution to my job loss that I experienced. Still severely depressed. Went through a fatique and burnout during the job. Was on 150mg. My doc asked for an increase and NO WAY! It didn't help one bit and I gave up after 7 weeks. I got switched over to zoloft and it worked much better. I am really 27, but am going to put 26 as my age since I was that old when I took it. F 26 7 weeks
11/3/2006
 2  Chronic Anxiety and Depression Much worse anxiety and depression. Slight insomnia. Pleasant Vivid dreams at first. Extremely lethargic - couldn't even watch TV. Sky high libido but too lazy to do anything with it. I started out on 150mg XL (Generic - Par) in the morning then titrated after a week to 300mg XL (Name brand) per day. I was so filled with anxiety and depression that I had to go on short-term disability at work. THEN the doctor titrated the Name Brand to 450mg XL once in the morning. I was a nervous wreck, couldn't think, too lethargic to do anything. Please keep in mind, I was also on 6mg (yes, 6mg) of Xanax XR even before taking the Wellbutrin XL. Well the 450mg dose made me a non-thinking, non-productive, shuttering shell. The doctor dropped me to 300mg and I still feel AWFUL! I have no Bi-Polar or any other condition but he is going to add Abilify to the Wellbutrin. I'm already insulin resistant, 50 lbs overweight and petrified of permanent Tardive Dyskinesia, Diabetes and extra weight on Abilify. Please offer some advice. Thank you much!! M 49 7 weeks
300mg 1X day
7/12/2013
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 5  Anxiety, panic attacks Mild agitation in the first couple of weeks, fatigue. This has been the best antidepressant for me so far. I Have tried a few SSRIs and had bad side effects, although celexa did take away my panic attacks (while making me feel like a zombie). This drug is not intended for people with anxiety or panic attacks, however it seems to have the opposite effect on me. I feel more relaxed, worry alot less and have a more positive outlook! F 35 8 weeks
9/11/2009
 4  Anxiety/Depression I experienced all the typical side effects associated with this drug, however most of them have now tapered off. Has worked great with the depression, but still having anxiety symptoms (physical side effects of the anxiety) This drug has worked really well for my depression, I no longer have crying spells for no reason. However, it has not done lots to improve my anxiety disorder. I am currently on a dose of 150mg per day, and my family dr. has suggested that I increase the dose to 300mg a day to conquer the anxiety symptoms I am still having. I am reluctant to increase the dosage as it was my understanding that this is more for depression than anxiety. Any thoughts? has anyone out there received benefits in the area of anxiety by increasing the dose from 150mg to 300mg? I personally don't want to go thru the insomnia and other side effects I experienced when first getting on this medication. Please email me to let me know if this drug has helped with anxiety. F 29 8 weeks
10/30/2008
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 3  Depression Anger, Irritability,headaches, dazed, confusion, forgetfulness,sadness, motivation,energy, weight loss, happiness I started taking 75mg 2x a day (the lowest dosage possible) and recently (this week) increased my dosage to 75mg 3x a day. I am glad I waited to increase because the first few weeks were hell. I was up and down and very irritable and had anger spurts. I hated it. My doc recommended I give it a try for 6 to 8 weeks. It gave me tons of energy and I lost 10 pounds in 6 weeks but I still had minor irritability. The doc decided to up my dosage by 75 and my anger spurts have returned. I called to get it lowered but they insist it will subsided in a week and I will be back to normal. I hope so. I hate this anger. I will let you know if it works because if it doesn't I am done with meds. I definitly suggest to anyone to start on a low dosage and work your way up gradually F 30 8 weeks
75 3X day
3/11/2010
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 1  Major Depression None Is this drug a joke? I was reading through all of the reviews and it seemed that people were saying things like it helped with libido and increased emotions, which is exactly what I wanted because of my anhedonic/apathetic/low libido symptoms, but let me tell you, I was disappointed. I thought for sure it would work or I would at least feel SOMETHING, but unfortunately, it felt just like a sugar pill. Are you kidding me? What a wussy drug. I was taking it with abilify also, which was supposed to "work synergistically" with it. M 20 8 weeks
450 1X day
9/16/2012
 1  major depression headaches, nausea, vomitting, restlessness, racing thoughts, anxiety, dry mouth, extreme weight loss, bitter taste in mouth, loss of sleep, loss of appetite, loss of concentration. worst experience with an anti depressant I have ever had. It has not not really helped my depression at all and if anything has decreased my rational thinking and made me feel sick all day long every day. F 25 9 weeks
300 1X day
7/16/2012
 5  SevereGAD, clinical depression, PMD At first, sore throat, anxiety through the roof, acne. All went away except the acne. I was "thisclose" to quitting WB XL after one week because of the dramatic increase in anxiety, which had been quelled by Zoloft for 1.5 years. Luckily I read somewhere just to stick it out and it will pass. Well it passed and I feel 1,000 times better than I ever did on Paxil or Zoloft - SSRI's were always my first choice (except Lexapro - that made me sicker and sicker) because of the myth that Wellbutrin causes anxiety in people with GAD. Not true in my case and I have had the WORST GAD! I gained 60 lbs on Zoloft and have lost about 5lbs in 10 weeks without really trying. I only take 150mgs and I was on 125mgs of Zoloft - I feel that Wellbutrin is very strong. Good luck! F 33 10 weeks
8/4/2006
 5  Migraine headaches The only side effect I experienced was dry mouth/throat which was quite uncomfortable, but much more tolerable than the daily migraines I had been having for years. Took a few weeks to help headaches -- they are completely gone! (Also taking Nadalol 30 mg. and Flexeril 5 mg. daily with the Wellbutrin XL). There are special toothpastes, mouthwashes, sprays, and gums for dry mouth that help lessen the discomfort. I am taking 300 MG daily of Wellbutrin XL. Tried MANY other medications and doctors for help with my migraines and NOTHING worked. Wellbutrin XL worked for me and gave me my life back. F 47 10 weeks
2/24/2008

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