WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Depression & Anxiety Anxiety, short temper, aggressiveness, loss of appetite, increased sex drive, increased energy, and overconfidence I requested that my doctor put me on this drug since lexapro was making me gain weight. At first 150 mg Buproprion made me feel crazy, aggressive, irritable, and very anxious. It led to several arguments with my husband. However when I combined it with lexapro (5 mg)it mellowed me out while at the same time countering the increased appetite urges from lexapro. I've been on buproprion for about a month and I requested the doctor switch me to 300 mg since my appetite was still pretty high. I've taken myself off lexapro and am just trying buproprion xl 300 mg and so far I like it. I've lost 5 pounds and have increased sex drives. The lexapro was good initially to counter the irritatbility and anxiety of buproprion but now these negative side effects of buproprion appear to have subsided. Being on 300 mg really helps me with my appetite. I feel very optimistic too. Just encouragement to others out there, it took several weeks to a month for my "crazy" buproprion side effects to subside. Until they subsided lexapro kept me in check. NOw that they appear to have subsided I am trying myself only on buproprion to see how it will go and so far so good, much less appetite than lexapro (not as mellow as lexapro) but very happy, very confidence, and desire to have sex. So hang in there if you have side effects, they may subside for you after 4-6 weeks. Until then you can take a supplemental drug such as lexapro etc to counter the side effects. F 37 4 weeks
4/19/2009
 4  depression anxiety I have tried others like celexa,zoloft,seroquel...this one is it. I feel amazing situations that would make me cry are more tolerable I look at things differently now...it is week 4 and I hope it just keeps getting better...I am more focused,doing more things I used to enjoy and also enjoying my family again...I have lost weight not sure how much I don't go on scale but I fit into my pre pregnancy jeans now with ease...this med has given me happiness back. F 35 4 weeks
300MG
12/7/2012
 4  anxiety I forgot to add that the ITCHING PHASE does not last forever! It was bad for a week or so in the beginning but I was determined I would get through it cause Wellbutrin was working so well. Now I have occasional itchy feet or hands but not nearly as bad and it's well worth it. It's my only remaining side effect. F 32 4 weeks
11/8/2006
 4  Depression at 150 mg none / at 300 mg insomnia, anxiety, some paranoia (I was terrified after watching scary movies), everything tasted like metal. Obviously this drug does not work for everyone and if it does work for some, it has different effects on people, be cautious if your doctor wants to increase the dosage from 150 to 300, instead insist on a gradual increase ONLY if needed. I felt great at 150 mg, like I haven't felt in years. Afterm taking the 300 mg for a week, I hated this drug, I insisted I be put back to 150 and have been feeling great since. Also quit smoking in 1 week after smoking for 20 years. M 40 4 weeks
1/6/2006
 4  Depression/anxiety Periods of more intense anxiety and compulsive thoughts, insomnia off and on, increased energy and motivation. Been taking XL 150mg for 4 weeks. Results are mixed. It certainly helped me get out of bed in the morning and gave me more energy and drive to get things done. However, there are days where my feelings of anxiety about things are much more intense than before, I seem to compusively dwell on my recent break-up. Seems to dull the effects of alcohol but hangovers are worse, wouldnt recommend alcohol. Not sure if this on-and-off general feeling of anxiety will subside, can anyone offer any guidance? M 25 4 weeks
11/18/2007
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 4  Major Depression Headaches, insomnia, dry mouth, low libido, and loss of appetite. I have beeb taking Wellbutrin for about 4 weeks now and it has helped a great deal. The only side effects that are still with me are occaional headaches, insomnia (take xanax to help me sleep at night), and low libido. I'm just noticing my sex drive being extremely low. Does this ever change? Or is there something I can do to help bust my sex drive? It's starting to affect my relationship. I don't want to stop taking it, but wish there was something that could be done about this. F 23 4 weeks
11/30/2008
 4  anxiety and depression Increased anxiety in the first 2 or 3 weeks- hopelessness /despair & thinking it wasn't working. After 3 weeks it was like a switch went off and I felt 100% better. Another side effect was jaw clenching and some muscle twitches which aggravated my TMJ, but it DID GO AWAY after a week or so. Increased sex drive- WOW!!! I didn't even realize it til a week or so later but I stopped drinking coffee- this stuff gives me so much ENERGY!! Difficulty sleeping went away within a week. I'm certainly still capable of anxious thoughts and hopelessness if I let myself go there- but it's EASIER to let it go. I feel very much in control of myself. I took Effexor right before the Wellbutrin and I had NO anxiety but I also felt LIKE A ZOMBIE- I didn't like that. I got off of that because of inability to orgasm. Wellbutrin does just the opposite! F 32 4 weeks
11/8/2006
 4  workload caused depression/anxiety WK1: by day 2 super increased energy & mood, insomnia increase (wake during night or nites of NO sleep), 1 laughing fit,1lb weightloss. WK2&3: jaw clenching dur sleep, newly acquired irritation/agitation - 6X/week, 2lb weightloss, incr libido (was near dead), less severe insomnia, incr appetite. WK4: better sleep (2 nite broken sleep, 1 nite no sleep), energy still up, mood better & more balanced, incr in libido, 1lb weightloss, some jaw clench day & nite. 1st time on A.D. 5ft, 105lb Asian F w med-slow metabolism. Light smoker. Take 1 x 150mg WellbutrinXL. Took at 8pm but insomniatic nites. Now take 3pm. Will move to noon (not up before 11am). Dr suggest 1/day x 10 days then incr to 2/day if tolerant. Insomnia & irritation made me not up dose. BIG surprise was weighloss. At 5ft, 105lb ONLY way I lose weight is STRINGENT diet & exercise, which i'm not doing. With WBXL, unlike others on here, I've appetite increase, seek carbs & sweets. Even so, lost 4lbs. VERY happy. Feel best near 100lbs. NO decreased smoking - I'm light 2-4 cig/day smoker. Still want to and enjoy it. Jaw clench annoying when I find I'm doing it. Teeth taking beating, think am nite grinding too. Happy libido returning. Hubby happy too. Hope it incr even more. Glad irritation subsided. HATED that. Normally very uppity person, so was big downer. Dr suggest add 25mg Seroquel to enhance WBXL, better sleep BUT S.E's R fatigue & weighGAIN. Anyone w ex F 44 4 weeks
3/28/2007
 3  depression dizziness, very nausiated, after i take it. it does not help with my chronic pain though. F 26 4 weeks
150mg 1X day
11/8/2010
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 3  Post Partum Depression extreme shakyness, twitches, vision changes, increase in anxiety, increased sex drive, hyper, loss of appitite, food is unappealing but i feel like im starving, still crave drugs, loss of balance, terrible insomnia, paranoia, worsend my OCD, joint pain, body aches. helped my negative feelings towards my life and baby. i love my baby more than ever, im not ignoring her or feel hateful towards her. still am depressed about my life and where its going. lost 10lbs the 1st week on it. a little more desire to keep up with chores. F 17 4 weeks
300mg 1X day
5/13/2010
 3  Depression dizziness, confusion, headaches, tremors, feeling zoned out - I noticed these side effects on day 8 of taking 150mg XL, these side effects went away in 4 days. On week 3 my dosage was increased to 300mg. I'm having the same side effects and it's awful. I hope they subside soon, I can't take it. Has anyone had the same experience? Should I stick with it? F 33 4 weeks
300mg 1X day
9/17/2014
Email
 2  depression, anger I cried for about two weeks after first going on. today was a bad day, I felt dizzy, high, and just plain strange. People kept asking me what I had taken to make me act this way. I can't concentrate, I oversleep, and I am EXTREMELY neurotic. Everything pisses me off. All the little things. I am trying very hard to control myself, but I just keep getting so frustrated. I think I need to come off. F 17 4 weeks
3/25/2007
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 2  Adult ADHD, anxiety, depression Rage and irritability- like constant PMS! Anxiety, heart palpitations, depression. I switched from Effexor to Wellbutrin XL. The Effexor was way more helpful with my depression and anxiety disorder- but did nothing to help the attention deficity disorder and the side effects were awful. Wellbutrin seems to hit the opposite notes-depression is coming back, as well as the anxiety, but I'm better able to focus and stay on task. I feel constantly irritable, though, and I feel dread of the future. I've been trying to just live moment to moment rather than think of the future. I've also had some anxiety problems- which I haven't had since before Effexor. F 35 4 weeks
12/29/2008
 2  smoking cessation Severe rash, spacey I took this to stop smoking, but had giant red, itchy welts on my stomach. Doctor told me they were better then smoking and to keep taking it. I could not deal with it. Took a week and a half for welts to go away after I got off it. F 29 4 weeks
1/31/2008
 1  post surgical anxiety Mostly insomnia and feeling tired all the time; irritability and edginess; bouts of depression and crying; dry mouth, constant thirst; frequent urination; constipation; tinnitus; forgetfulness; threw off my menstrual cycle. I couldn't wait to get off this medicine. The side effects wern't worth it to me; they did not subside, even after a month. Thank God for Zoloft. F 43 4 weeks
5/29/2006
 1  mild anxiety Major:Anger, paranoia, mania, aggression, agitation, crying, depression, severe changes in personality. Mild: dry mouth, change in taste, slight vertigo, occasional nausea I was on Zoloft on and off for several years do to GAD. I was very stable and happy, but switched from Zoloft to Wellbutrin because Zoloft caused moderate sexual side effects and I was entering a new relationship. This was the biggest mistake for me ever. I started on 100mg "Watson" wellbutrin and gradually increased to 300mg XL daily in the course of 4 weeks. I became manic and had sleep issues but thought I would "ride it out". Once I was put on 300mg I immediately knew it was a mistake. I started becoming extremely agitated and started to have panic attacks (never had history of this). I could not concentrate at work and could not control outrage bursts (again, not a history of this). I stopped 2 days ago and I am extremely tired and have a migraine (have hx of migraine). I had to call my parents and have them immediately pick up my young kids because I was afraid I was going to hurt them (NEVER EVER HAVE FELT THIS BEFORE!). I think this drug can be very dangerous and I caution anyone who started feeling any of these symptoms to STOP immediately and call their doctor. I am a nurse and work in an ICU so I would not be able to have that job if I was like this "normally"...it changed my personality 100% for the worse. I went from calm loving nurse and mommy to monster in 4 weeks:-( I am very sad by all this. The worse is I am aware this is all crazy and med related, but cannot control it. F 33 4 weeks
300 1X day
3/11/2011
 1  Depression Nausea, Headaches Dizziness, Lightheadedness, Fatigue, Dry Mouth, Tinnitus, Anxiousness, Increased Agitation/Irritability, Drowsiness, General Abnormal Aches and Pains. M 18 4 weeks
150 2X day
12/19/2012
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 1  anxiety, depression increased anxiety, insomnia, tinnitus, nocturnal priapism I had no positive effects from generic Wellbutrin XL. I'm not taking it anymore, but after I increased my dose, I had a priapism in my sleep, and I'm still suffering from the damage to my penis 6 months later. M 28 4 weeks
30mg 1X day
4/29/2012
Email
 3  major depressive disorder Start of week 5 still having mood swings, crying episodes etc. Seems to have turned me from normal flat emotions into bipolar At meeting with shrink on start of week 5 he got scared and took me off the Wellbutrin. Apparently he was very worried about the mood swings. We are now trying Lexapro plus a mood stabilizer. Feel a bit better after just 2 days now. I was prepared to stick it out with the wellbutrin a few more weeks, but the shrink was highly resistant to that notion. M 37 4.5 weeks
150 1X day
2/24/2011
Email

Patient History
 1  Severe depression compulsive eating Hardly noticed I was even on anything. The only possible side effect is it's making my depression WORSE. I had high hopes and was let down. Nearly 5 weeks on it and nothing. No help for my depression whatsoever, if anything I feel worse. No help whatsoever with my compulsive over eating. It is useless. F 22 4.5 weeks
150 mg 1X day
7/23/2010

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