WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Depression strong sexual urges the first 2 weeks. Week 4 broke out in a rash. I felt as if a light went on. I felt like my old self unfortunately I'm allergic. F 32 5 weeks
300 mg 1X day
4/29/2010
 5  depression Dry mouth after sleeping, slightly increased energy throughout the day, increased sex drive, weight loss, decreased appetite, loss of interest in food when eating I began taking this med 5 weeks ago for depression. For the first 3 weeks I did not notice any alleviation of my symptoms. However, when I went back to my physician and told him this he switched me to a 200mg tablet and advised me to take it twice daily for a 400mg/day dose. Within a week I noticed a significant change in my mood (for the better). I also lost 10 pounds within the first 4 weeks of taking the drug. M 25 5 weeks
150mg 2X day
10/14/2010
 5  Lyrica-induce depression, GAD Irritability, rage-management issues Wonderful, wonderful wonderful drug! It really works on depression&anxiety, where SSRIs and benzos had failed!! It also restored libido to normal levels, after Lyrica had wiped it out. M 30 5 weeks
225mg 1X day
5/17/2012
 5  chronic depression, social anixety More alert, no change in weight or libio I wanted to contribute my own experience because I found this site helpful when I was considering Wellbutrin. I have had chronic depression and have social anxiety. I started on 150 XL for about 3 weeks and then went to 300. Generally it has worked well for me. I was taking lexapro and although it helped me not feel so depressed, it made me quite tired. I would nap as often as I could. It seemed to effect the way I dealt with thing throughout the day by seemingly making everything o.k. to the point that a lot of things didn’t matter. Welbutin on the other hand has had an almost opposite effect. Rather than being tired, I’m more alert. My expectations were high (magic pill) in part because of reading mostly just the highly rated comments on this site. I was trying to look positively at things. On that note, I would recommend readers to consider a fair sample of all, good and bad, experiences others have had (everyone’s different). I had expected to eat less and have M 50 5 weeks
3/13/2007
 5  bipolar I Kind of spacy, sleeping all the time for the first few days (which isnt so bad because I had not been able to fall asleep before 5am for months before this), maybe joint pain, increased thirst I was in a really depressed for 6 mos and it got to the point where I wouldnt be able to leave my house or go to the gym (did all workouts at home), suicidal thoughts ,really morbid. I'm bipolar I so Im also on the mood stabilizer lamictal. I havent had any suicidal thoughts in a while... which is good because even when Im manic I am usually still suicidal . Im social again, Im more easily able to feel things and am starting to piece a very broken life back together. ps ive never been someone who has ever belived in medication, i always thought I could treat all of my problems myself; excercize(6days p wk), juicing jack lalanne style, organic food, whole food vitamins all that stuff and depression would go away, but ive realized manic depression just isnt soemthing i can beat on my own F 22 5 weeks
2/17/2007
 4  Smoking cessation It's odd because all of the potential side effects are pretty much the same as quitting smoking. The only major, unaccountable, side effect that I had was a feeling of extreme heaviness in my legs in the time where I was still smoking and on the drug as well. But this led me to quit quicker and it went away once I did. When I first started taking the drug, my stomach was upset almost every evening - this went away after about a week but I still get upset stomach on occasion. Also, I am pretty restless at night and have trouble falling asleep. This may have partially to do with the fact that I used to have a cigarette right before bed and my body still expects that signal to fall asleep. I am only staying up about 45 minutes later than I was before I went on the drug, however. There was also a small bit of fogginess and speaking fast/euphoria when I first started but this went away very quickly. I really don't like taking drugs. I'm actually diagnosed anxiety disorder and was prescribed Xanax in the past (and as a child was on Ritilin). I had such a bad reaction to Xanax that I've chosen to be without any drugs to treat my condition for 12 years now. The Wellbutrin effects were so minor in comparison and has shut down the little "you need to smoke" voice in my head so much that it's been entirely worth it (I was able to quit after only eight days of taking the drug and the voice was shut down almost instantly). I've now had four weeks with very few urges to smoke. If I were prescribed it to combat my anxiety disorder I would stay on it indefinitely. Though I do have to say the "don't drink or you could have seizures" is a real annoyance. M 31 5 weeks
4/27/2006
 4  Depression/OCD Dry Mouth, Spaced Out, Insomnia Although I'm still smoking, it doesn't taste the same and I plan to stop smoking this week. I Took 150mg for a full month and then switched to the 300mg. The dry mouth and insomnia came back when dose was upped but should go away after about a week or two just like it did when I was on the 150mg M 36 5 weeks
11/29/2006
 4  Depression, Anxiety I have experienced all the usual side effects with this drug, ranging from insomnia, nausea, loss of appetite, feeling in a fog, etc. etc. however these seemed to have subsided. I have been on this drug for 5 weeks now, can someone please tell me if you have epxerienced increased irritability with this medication, and if so, has it gone away in time? I am a little concerned because I feel very snappy, and not quite myself, but I am confused since the doctor said this could not be caused by the wellbutrin. Please feel free to share with me your experiences. Thank you. F 29 5 weeks
10/16/2008
Email
 4  depression Anxiety/insomnia at first; decreased appetite (a GOOD thing!); increased energy Took lexapro for 2 years. Felt like I didn't care about anything but just had a "numb" feeling. Gained about 15 pounds and wanted to eat all the time. Tired all the time. Since wellbutrin, I feel alive again! I have lost 9 pounds in 3 weeks, and don't feel like eating the kitchen counter! Everything in my house is clean now! I have noticed I am a little quick to anger sometimes, but I have read that it passes after awhile being on wellbutrin. F 41 5 weeks
11/10/2007
 4  ADD, Depression, Anxiety Nasuea, decreased appetite, memory loss(i dont know if this side effect is even possable but i dont know what else it could be from i just find i cant exaclty remeber the past few days or events or even things i say), teeth grinding, compleatly zoning out when others are talking. deffinatly helped with my irratiblity, i have been taking 150 mg over a month now, has not helped much with the ADD but depressing and anxiety level are greatly improved. F 18 5 weeks
4/15/2007
 4  Anxiety At first, dizziness, racing heart, very vivid dreams, sleepy at times. A day or 2 of stomach issues but that went away quickly. It took about 3 weeks for the side effects to gradually go away. Also, I have basically given up caffine coffee and wine. The effects of wine and coffee are greatly enhanced. The good side effects (at about 3 weeks): no food cravings and the sex drive is back. I decided to switch from 2 yrs of Lexapro to Wellbutrin XL, after gaining 25lbs. I started Wellbutrin XL at 150mg for the first week, then upped to 300mg per day after that. The first couple weeks I had the bulk of the side effects and my anger/anxiety issues rapidly came back. It was terrible. I was considering going back to Lexapro, but decided after reading here, to keep going. Gradually at about 2.5-3 weeks, I realized all the ugly thoughts were gone. I noticed I wasn't as emotional, I was calm again. I noticed my food cravings were gone. I could walk through the candy zone in the stores and not give it a thought. I then, realized my sex drive is back. I am now at 5 weeks and so far, I sticking with it. I don't have the warm calm feelings I had on Lexapro but I feel good in so many areas I don't want to go back to Lexapro. Also, I have lost about 6lbs in 3 weeks. So far, Wellbutrin XL is giving me more pros than cons. F 47 5 weeks
9/18/2006
 3  depression Terrible insomnia, freq urination, can't shut off brain, foggy brain, worry constantly WHEN WILL THIS WORK ?? Some days I feel like I am in Hell. Have a very stressful job and after years on the job I now -sometimes- forget my password! ??? After cancer diagnosis Dr. put me on anti-dep & anxiety meds. 10+ years later I am trying to get off of paxil (also took zoloft for years) after gaining 30 pounds, losing short term memory and having no sex drive. Dr. also weaned me off of Ativan. With Wellb XL, I have to take trazadone to try and get more than 4 hrs sleep a night...so far 75mg of sleeping pill do not work either. I do like the fact that my appetite has demished, but when will I stop crying? Think I should insist on an anxiety med? Dr.(Gen Pract) seems to be AFRAID of prescribing meds for depr/anxty. She is supposed to help me get better, right? I do NOT want to go back to paxil EVER..gaining 30 pounds in 10 years is enough to make anyone depressed ! F 52 5 weeks
300mg 1X day
9/10/2010
 3  depression Bad taste in mouth, nausea, flushing, aching leg muscles, difficulty with memory, forgetting common words in the middle of a sentence. I'm no longer angry all the time and I don't feel like I have a chip on my shoulder any more. I'm not so stressed out and overwhelmed. People tell me I seem more relaxed and upbeat so I suppose it is helping me in social settings. When alone I am still experiencing crying jags and thoughts of inadequacy, alienation, and self-doubt. I am definitely doing better when I am around people, but I'm about the the same or worse when I'm alone - with the exception of improvement in feelings of anger. F 43 5 weeks
9/9/2007
 2  depression extreme anger, weight gain, bitterness, did i mention being angry?? i have no insurance so i purchase the generic. i was on lexapro for 2 years, pristiq for 2 weeks. lexapro made me want to sleep all the time, plus no sex drive and weight gain. i don't know that i was on pristiq long enough for it to do anything. once again, no insurance so i can't afford it. i don't know why my doctor even put me on it... when i had all 3 drugs in my system..wow, that was awful!! and awful is an understatement!! the wellbutrin seems to be good for my sex drive, but that's it. i'm gaining weight with wellbutrin, and that makes me angry as well. but everything seems to lately. i was prescribed 300mg per day, i started by taking 150mg per day. now i take 150mg one day, 300mg the next. i keep hoping it's going to work but i have been strongly encouraged by family and friends to find something else because this isn't working for me. they tell me i'm a totally different person. i'm usually so laid back, and not one to speak up. i still don't speak up, esp. to the ones that F 41 5 weeks
11/2/2008
 2  depression anxiety, dry mouth and a sinking feeling from my chest down to my stomach has anyone else had this happen? it like the feeling you get when you forgot something at home you needed or when you lean back on a chair and almost fall... please help i need to know how long this sinking feeling from chest to stomach will last, if it keeps up i will have to stop taking this medication M 31 5 weeks
1/3/2008
 2  depression headaches during the first week, a brief period of wellbeing (3 or 4 days)after the first week. Increase in energy, but also much irritability. Rash on upper right shoulder, chest, and across lower stomach. Increased cravings, particularly for chocolate and italian food, and of course resulting weight gain despite exercise. No change in sexual function. Overall mood neither elated nor depressed,just neutral or irritated. took 150 mg xl for about 5 weeks. Switched to fluoxetine after five weeks of wellbutrin; noticed a huge difference when this was added. A wellbutrin combo with another drug may work for some if wellbutrin alone has some benefit, but not enough by itself. Eventually discontinued wellbutrin- irritability was like having PMS all of the time. Toyed with the idea of going to 300mg, but did not want to chance the side effects worsening rather than improving. F 48 5 weeks
4/30/2008
 2  Bi-Polar, Depression Tin taste in my mouth, hair loss, "forget" to eat, vivid dreams (I liked this because with other ADs I had none), Irritible & Angry at 300mgs Started at 150mg for about 3 weeks. The beginning was fine because it was better than the drug from hell I was on prior, Effexor. Leveled out and became totally depressed. Increased to 300mg which made me aggitated, snappish and flat out mad and angry. Never did stop me from wanting to smoke. I'm switching off this dud. F 37 5 weeks
5/2/2008
 2  ADHD, Anxiety, Depression Extreme irribility,nervousness,social anxiety,dry mouth,headache, worsening depression,drowsiness, stuck on certain thoughts, Seems to make my ADHD worse. This drug did not help me. I cannot wait to get off it and try something else. The irribility has caused numerous fights with the wife. Would not recommend for anxiety and ADHD. M 30 5 weeks
150 mg
5/28/2015
 1  bipolar II - weight loss Regarding the comment of the patient below who wrote: PLEASE!!! DO NOT TAKE BUDEPRION MADE BY TEVA!!!! DO NOT LISTEN TO ANYONE TELLING YOU IT IS THE SAME AS THE BRAND NAME!!! *This person is right on the money! Take these words to heart! Even my shrink has heard this...he does not argue with this!* I am nauseous 90% of the time (not even to the point of vomiting to relieve it), diarrhea/soft stool, brain zaps almost *unbearable* to where I cannot function--they make me so damn irritable! The nausea starts, I chug Coke Zeros to temporarily relieve it---when my stomach can't handle that anymore, coffee offsets the soda overdose. It is a horrible cycle! If I still worked in an office, I would have taken so many sick days I'd have been fired by now--I'm thankful I got laid off! All I want to do is lie down and doze off so these shitty side effects would leave me alone! That works for several hours, I get hungry, I eat a little something, the cycle resumes! Lost 14 pounds, which was badly needed and greatly appreciated, but this poison is just not worth it!!! The side effects are depressing the hell out of me and intermittently send me into complete despair! I made the STUPID mistake of alternating it with the brand name for FIVE DAYS when I was finally starting to feel better (taking the REAL THING was beginning to work well after about 10 days) to save money and now I want to kill myself---not even because of the depression end of it or suicidal thoughts, but because of the physical torture! I am trying to be patient and wait this out but it is PURE AGONY!!! F 40 5 weeks
4/3/2009
 1  depression tired F 31 5 weeks
9/30/2009

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