WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  anxiety panic trouble sleeping, extreme sex drive Wellbutrin XL was different than other anti-depressants I had taken. I had loads of energy but that lead to alot of sleep problems. I had the strongest sex drive I have ever had in my life for about the first 6 months I was on it. It helped me get over my food cravings. F 33 2 years
6/25/2007
 4  Depression On the generic I had quite a bit of anxiety and also experienced some hair loss Wellbutrin worked great for me, saw a dramatic improvement in my mood and energy level. First tried the generic but had an issue with side effects, so now I only use the brand medication. They have a coupon on their website, which helps keep my costs down. F 39 2 years
300 mg 1X day
6/9/2011
 4  depression, PMDD headaches, dry mouth, increased alcohol tolerance, decreased appetite (temporary) I've been on this drug since 2007 but went off of it while pregnant. Since the baby I have been taking 150mg. I think it's helped with the overwhelming emotions that come from being post partum. Having said this, DO NOT DRINK ON WELLBUTRIN!!! I just pieced together why I feel so crappy after a night of drinking. The Wellbutrin stops working--I get a terrible hangover and feel extremely vulnerable, suicidal and depressed when I mix it with alcohol. Also, funny enough, it has not done a thing for my libido (and it didn't in the past before baby). I'm considering upping to 300mg.... F 29 2 years
150mg 1X day
3/22/2010
 4  Depression -ADD sleeplessness Wellbutrin XL 150 has brought color back into my life. Things are just clearer for me, I have been able to deal with issues and move forward. Wellbutrin does not help with obsessive thoughts as an SSRI does however, SSRI's cause anxiety so I am only take the Wellbutrin. F 52 2 years
7/21/2008
 4  depression With the Wellbutrin XL 150mg: weight loss, dizziness, loss of appetite, increased mood and more energy....... With the Wellbutrin XL 300mg: I have only been taking it for about a week so i haven't noticed a big change in my mood yet, but I have been more tired during the day and a couple days ago I realized I had a faint rash on both of my upper arms. I still have more motivation, but the changes I was looking for in the increased dosage haven't happened yet... Prior to taking WXL 150 I was on Paxil which caused me to gain weight and loose my sex drive... not pleasant. It had bad withdraw effects so it took me awhile to completely come off of it, but I'm so glad I did. Wellbutrin has made such a difference. The side effects were never severe enough for me to stop taking it. I'm still waiting the 300mg out to see if the drowsiness goes away... F 22 2 years
4/7/2008
 4  PPD, Major Depression Dry Mouth, Initial Insomnia, Slight Loss of Appetite, Increased Energy, shakiness, constipation First of all, everyone needs to specify whether they are reviewing the GENERIC or the BRAND NAME because these are NOT THE SAME. After initial success off Wellbutrin XL, 300 mg, my isurance company switched me to generic BUPROPION XL. I never thought anything of it, thinking the generic was the same. After months of returning depression and anxiety, research made me realize that there were problems with the generic and I immediately had my doctor switch me to the brand name again, which helped my depression. For everyone who is having the horrible side effects, I hope they try the brand name and give it a chance...it worked MIRACLES for me. The generic is defective, with problems of dumping too much of the medication in the bloodstream at once, instead of extended release, as it is supposed to. The FDA only tested a certain dosage, and it can still be approved if it is "slightly" different. At higher dosages, which they never tested, even MORE problems arise. I hope e F 30 2 years
12/9/2008
 4  Depression, bipolar depression Ears ringing constantly, fuzzy head, mood swings Went from 150 to 300 to 450 mg per day, as at each step I felt it had stopped working. Added Lexapro 10 mg and mood swings subsided. Ran out of Wellbutrin a few days ago and couldn't get in contact with pDoc so I've been off of it for a few days. I feel much better mentally, clearer I guess, although more tired than usual. I don't know if I'm going to go back to taking it. M 26 2 years
11/29/2007
 4  Severe depression No libido; frequent urination and ongoing incontinence; sweating; stopped gaining weight from Celexa; sleep interference when taken alone Switched from Celexa due to extreme and non-stop weight gain; cannot completely remove Celexa or depression returns but am on Wellbutrin XL in the morning, 1/2 pill Celexa every 2nd night and it's working well. Weight has stabilized but not reduced tho I noticed a reduction in appetite. Very happy with the combination, but with Wellbutrin alone I would not be able to sleep. Would have to reconsider if I got into a relationship due to complete lack of libido. F 49 2 years
10/18/2007
 4  depression weight loss, higher energy, able to deal with stress better, relief of depression symptoms When I first started taking Wellbutrin I lost a lot of weight without diet or exercise. I'm not sure if I was eating less and not realizing it, but I kept losing weight with no effort. About 6 months later, I gained it all back and more. Not sure if it's from the drug but the doctor doesn't even think wellbutrin has an affect on weight (i disagree) F 23 2 years
7/11/2007
 4  ADD and Situational Depression This is my 3rd time on W. The first time was great! It removed the fog. I had to go on Lorazepam, though, to help with sleep because of W. The second time, after another particularly challenging period of time, I couldn't stay on it. I developed this weird eyebrow tick as soon as I started and it stopped as soon as I got off. Sleep is the biggest problem for me on or off W, but on W, it's worse. Manageable, though, and very much worth it. Slight increase in sexual function (specifically, stronger erection, wilder orgasm). This drug does help the ADD somewhat. In fact, I can go off ADD meds while on it and my desire for, and intake of, caffeine drops while on it. For the depression, it's like, "Wham!!!" It just activates and I see colors again! I feel confident and energized on W, which definitely helps the depression. Still, though it's not a miracle and I'm probably going to add Lexapro for obsessively thinking about a lost relationship. Again. Aghh... One other thing. I tend to smoke when I get really stressed. Perhaps the biggest benefit of W for me is that it just KILLS the smoking thing dead. M 46 2 years
8/29/2007
 4  Depression, OCD, to quit smoking First few weeks only: Major headaches, ringing in ears, excitability, slight weight loss, reduced urge to smoke. I know many of you are considering increasing your dosage to 450 mg. I did (about a year ago)- - and it continues to work for me. Before, when I was taking 300 mg., I accidentally forgot I already took the medicine and took it twice in one day (600 mg.) I never felt better in my life! I told my doctor and he said to go ahead with 450 mg., 600 mg. was way too dangerous. I do, however, wonder if the drug is losing its effect...but not so much that I want to go off of it. My doctor recently added 25 mg. of clomipramine into the mix and it has helped with the OCD tremendously. For those of you starting out with Wellbutrin, please try to ride out the awful initial side effects. I know the headaches and ear-ringing are terrible...but hopefully the benefits will soon outweigh these pesky effects. The weight loss is GREAT, but for me, it was short lived. Lost 5 lbs in the first week. But then didn't lose (or gain) any more. For those of you who take those heinous SSRIs (at least they were for F 35 2 years
8/1/2007
 4  Severe depression Dry mouth, anxiety and racing heart, which all subsided (for the most part) after several months. A large caffeine intake can still get my heart racing again. The increased need to urinate seems to be sticking around. I experienced good relief from depression and a decrease in appetite (and my road rage all but disappeared), but after two years, the effect seems to be wearing off. Moving up to 450 mg might help, but the side effects were scary and I'd prefer to be on no drug at all. Has anyone who benefited from it ever stopped taking this drug without the depression returning? F 43 2 years
8/6/2006
 4  Depression Itching/rash on the arms - hope it passes, I thought my wife may have changed detergents which caused the ithching but now it seems it is the medicine. I also am not tired until about 12pm, only sleep in 2-3 hour intervals. Tired a lot. Mind is racing but am constantly fatigued. Memory problems. I just moved from 150 XL twice a day to 300 XL and then the rash started. I am going to ask my doctor if I can decrease to 150 XL and add low dose Prozac for balance. M 2 years
12/21/2006
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 4  mood elevation; improve libido Constipation, occasional headaches and weight loss. Otherwise, unremarkable. I've been on Wellbutrin XL 300mg for 2 years. It helps mild depression to some extent and modulates irritability and mood swings. I'm also sure it improves my libido. Don't expect overnight results or a sense of euphoria. M 44 2 years
7/10/2006
 3  anxiety Ringing in the ears, severe dizziness, nausea, mood swings, body aches, strange "zaps" in my "body" (kinda hard to explain, just like being mildly shocked every now and then), strange flashes of light when i close my eyes at bedtime, i switched from Effexor to Wellbutrin about 2 years ago ... recently (last few months) i was upped from 150 to 300 mg. Slowly i started noticing dizziness/vertigo, nausea in the AM. I am a moderate drinker, and have recently quit ... it seems the vertigo is worse. Would love to hear from anyone experiencing the dizziness. M 35 2 years
12/17/2007
Email
 3  depression and SAD I have been on it for 2 years, I have a lot of side effects such as: dizzyness, extreme dry mouth, disorientation, extreme weight loss, night sweating, really vivid dreams, shakes. I have experienced an extreme boost in metabolism which is good and bad. I am very fit looking, but I have to eat a lot to even maintain that. I eat probably 3 times more then i did before and yet i'm 15-20 pounds lighter then I was before takeing Wellbutrin XL. It's great for weight loss, not good to take if you are an anxious person or are prone to anxiety attacks. Side effects change every day and so does there severity. (ex: 1 day your dizzy, the next day your not but have dry mouth and shakes) F 24 2 years
11/14/2007
Email
 3  Depression (& ADHD) Immediate (days) increase in morning resting HR (44bpm to 54bpm) (How does this affect athletic performance?). Dry mouth, insomnia, initial agitaion. M 35 2 years
12/22/2005
 3  Depression Feel full easily after not eating much, anxiety, anger, irritability, hot flashes, sweats My anxiety has gone down, and it seems to help depression somewhat. It doesn't cause weight gain, or laziness, lack of motivation like ssri's do. F 56 2 years
450 1X day
5/3/2015
 3  depression Only side effect is increased anxiety. Have to completely avoid caffeine. M 56 2 years
300 1X day
7/4/2017
 3  Depression/ Mild Anxiety severe insomnia, irritability, angry outbursts, impatient with my children, tinnitus, constipation I have been taking wellbutrin 150mg daily for 2 years. It did help with my depression but not with my anxiety. After researching this drug I now realize this is the cause of my irritability and intolerance. I used to shout at my children and felt like I was the worst mother ever. I decided to quit taking it 1 month ago and now I am a different person. I am no longer shouting at my children and can talk calmly with them when they misbehave. My husband cannot believe the change in me. He says I appear less stressed, more content and am not continually nagging him like I was. I feel fine with no depression, I hope this continues. F 42 2 years
11/6/2009

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