WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Severe Depression I've found that Wellbutrin has been the only thing that has worked for me thus far- but CANNOT take the generic. I've tried to transition to the generic form on 4 occassions d/t insurance issues, money issues, MD request, etc.... it has caused me to slip into a deeper depression and it was only after a SELF Magazine article pulished in 2008 or 2009 about the generic forumlation causing worsening depression -that I realized that was the same thing that happened to me... to this day, I will gladly pay the difference in the price of the original trade name and will never go generic again. I have had no sexual side effects. I have had no adverse reactions. I only wish it gave me more energy and motivation. I went through several deaths in the past few years and have titrated up/down the dose scale between 300-450mg. F 41 3 years
300 -450mg 1X day
8/22/2010
 5  Depression I take the generic by Watson. I changed to a different pharmacy that used Teva and within a short time my depression and anxiety were back. It was like I was taking a placebo. The Teva gemeric is totally useless for me. Once I switched back to the Watson generic, my depression lifted completely. F 57 3 years
300XL 1X day
11/5/2010
 5  Severe Depression Briefly during first 2 weeks, dizziness, delayed speech and thought, occasional faster heart rate. Continuing side effects, return of a healthy sex drive, dry mouth after sleep, constipation, insomnia, weight loss and loss of compulsive eating, increased motivation and energy and ability to problem solve effectively. This medication changed my life. The depression ceased almost immediately which is rare. I lost 20 lbs, began to exercise and eat healthy, and short temperedness went away. In spite of more extremely stressful life conditions it has helped me stay the course. People comment how young I look which is true. I attribute this to weight loss and the absence of anxiety in my face. I eventually needed more help after 2 years and added 15mg Deplin 1x daily. Another medication that has really helped me. To combat constipation I take 2-stool softeners at night. For sleep, I started with 50 mg of Trazadone nightly which after 2 years we changed to 100mg nightly. I have no side effects or ever experienced headaches. This medication really works for me and made me aware of how much I needed it many, many years prior. F 53 3 years
300 mg 1X day
11/28/2010
 5  Depression One side effect I'm having, that I was wondering if anyone might have any suggestions as to how to improve, is that I can't seem to drink any alcohol at all. I've been taking Wellbutrin for a few years now and used to be able to have one or two drinks every so often, but can't anymore - I feel like it's like alcohol poisoning or something. Anyone have any suggestions? I like Wellbutrin enough to stick with it, but I'm wondering if maybe I skip my dose (150 mg) the day I'd like to have a glass of wine if that might help. I don't drink very much but do enjoy socializing with friends occasionally and would like to still be able to have a glass of wine once a month or so if possible. F 43 3 years
12/11/2006
 5  Severe Depression A small bit of anxiety at first but it was tolerated well Like I said I had severe depression for some time after life not being so kind to me from failed relationships romantic & friend wise to the sudden death to my mother with her being fairly young. My doctor prescribed me Paxil Prozac,Lexipro and all other junk SSRI's they have on the market. I started with a dose of 150mg which worked fine for a year or so but with me being 230 pound powerlifter I needed to up the dose to the 300mgXL which suited me alot better for my hectic lifestlye working in the soft drink industry which puts heavy demands from delivery off the truck. So if you need relief from dpression or other related problems skip the SSRI's the doctors like to prescribe it will just be a waste of money & time & give Wellbutrin a try. M 31 3 years
6/15/2006
 5   none I love it. F 39 3 years
5/8/2007
 5  Dysthymia Intense, movie-like dreams and interrupted sleep; a little bit of irritability (I added a small amount of Buspar to combat these side effects; it was a very effective combo) This was a wonder drug for me. I actually got to feel what "normal" is for the first time since I was a really small child. I lost 50ish lbs over the 3 years I was taking it, and was finally healthy. They've taken me off it b/c I had a seizure a month and a half ago. Now I'm relapsing and have gained almost 20lbs. I would have taken it for the rest of my life; I'm sad. I quit it cold turkey and did not have any bad side effects. F 26 3 years
6/25/2007
Email
 5  anxiety Minor effects. Dry mouth, occasional insomnia. Huge benefits... my confidence levels changed so much everyone has commented. I am far more motivated than I ever used to be and feel great all the time now. I don't care what the FDA says but there is definite difference between the Wellbutrin XL and the generic. The generic gets absorbed much more quickly and then drops off very rapidly. It was a freak'n rollercoaster. The generic's price is better but definitely not worth it, on the other hand, since the generics came out, my insurance company increased the co-pay from $20 to $130. I split the difference and get the good-stuff from Canada now. say "Yes" to National health care. say "No" to being screwed by Insurance companies. M 55 3 years
6/3/2008
 5  Severe Depression No bad side effects. only insomnia, weight loss and the fact that it worked The insomnia was not bad becuase there was no crash later from being so tired but not being able to sleep. It was just constant energy. I had appitite lose awsome. I felt Sort of euphoric at times. There was a time when I didn't think it was working to its fullest so doc put me on Lexapro also. Lexapro made it suck. Although my sex drive was great from the Wellbutrin xl, I could not climax AT ALL. That left me way too sexually frustrated. So I stopped the lexapro, and two days later i was back to normal. Eventually, I got rid of what was making my life miserable, and the Wellbutrin worked even better. Since I thought I was naturally happy, I got off it. After months of no meds, I was driving myself crazy, and everyone around me. Even though my life was wonderful, I always found something that made it awful, even if it was manufactured. So i realized I really needed it to stablize myself. So I went back on it. and poof, all better. weight loss started again too. But then, s F 28 3 years
4/30/2008
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 5  depression dizziness, shortness of breath, intense hunger (even after eating), shaking I was on Paxil previously and also this. This drug has helped me so much. F 20 3 years
4/2/2008
 5  Anxiety, depression I have taken this medication on and off for the last 3 years. I was treated with opiates for a severe car accident. One day I realized the opiates were making my brian mush, and destroying my attention span, so I attempted to stop taking the opiates. Little did I know the horrors of opiate detox. Once again, I started taking wellbutrin at my doctors urging. It was a life saving drug for me. For me, (maybe from the opiate detox period) the Wellbutrin worked great the first few days with an immediate marked difference, the second week was rough, but the third week an on was miraculous. I still cannot believe the difference. I have a terrible back and fibro. This medication along with a CNS suppresent like Horizant has killed all of my pain. I want to cry now thinking about what it took to get where I am today, 100% pain free. Please people, don't rely on opiates alone. There is good medication such as this that doesn't have the risks as opiates do. Eventually opiates actually made me hurt MORE due to long term use. I NEVER abused mine in the slightest, it is just a side effect of long term use. The wellbutrin gave me my life back, both from depression, anxiety, and opiate withdrawal. I really hope that physicians see these reviews and can recommend this drug to those going through opiate WD. F 36 3 years
300
6/9/2015
 5  depression slight memory loss M 38 3 years
8/4/2009
 5  Extreme Depression Only side effect was weight loss. The weight loss was a good side effect because 1/3 of the depression was from weight gain. Lost 30 lbs, depression subsided, thus I have been able to continue being a caregiver for my husband and my self confidence and overall wellbeing improved tremendously. Have been on Wellbutrin XL for 3 yrs. F 44 3 years
7/25/2008
 4  depression/extreme fatigue/sleepara ringing in ears. insomnia. constipation. One day I accidentally took two 300 mgs (i'm only supposed to take one 300 a day) and I flipped out and had a panic attack weird vision problems and hullicinations. I was put on this medication because all other antidepressants make me tired and make me sleep all the time. this one stopped that but now i have insomnia...but atleast i get things done...i was sleeping my life away. I stopped taking it just to see how i would do (after a couple years) I went back to my old sleepy self (accidentaly falling asleep..very dangerous)had sleeping paralisys (cant spell antipsychotics made me dumb)again which is very scary...and became hateful like i used to be. I decided I could handle the side effects because i cant handle my old lifestyle. I also used to feel blue and hate everyone around me and everything...that totally changed I am way more optimistic being on wellbutrin XL (300mg daily) HOWEVER BE CAREFUL FOR ACCIDENTAL OVERDOSE. I also do not reccomend this to anyone who drinks alcohol (very dangerous and can lead to accidental overdose) F 22 3 years
6/19/2009
 4  severe depression, anxiety memory problems, both: short & long hairloss wonder drug - saves my life. generic didn't work at all! F 55 3 years
8/18/2009
 4  depression, seasonal affect disorde lightheadedness and nausea first two weeks. Excellent treatment especially for seasonal affect mood disorder and energy level. In my case, Wellbutrin alone was not completely effective. With the addition of Prozac, my depression and irritability almost completely subsided. Further, prozac is great for the treatment of PMS symptoms. So, dont give up, eventually the right med or combo of meds can be truly effective. F 47 3 years
11/22/2008
Email
 4  depression none F 22 3 years
2/5/2009
 4  ADD/ADHD, mild depression Very few - some insomnia on higher (300 mg) dose, sometimes increased heart rate about an hour following a dose, slightly decreased appetite Didn't work as well for my ADD as I would have hoped, but there was still some benefit. Definitely helped even out my mood and temper (though I still had some irritability/anger issues), and without many of the negative side effects (e.g. sedation, sexual side effects) caused by many other antidepressants. Doesn't do much for anxiety, however. Had to stop taking as it was too expensive and not covered by my insurance. M 30 3 years
7/24/2008
Email
 4  depression Very helpful drug. MUCH better than the generic version!! F 20 3 years
7/24/2008
 4  I take it for depression and add Irritable, still get the mood swings.. I eat more sumtimes then other times.. Otherwise i'm doing much better, then when i wazn't taking anything. Sent e-mail message From: [email protected](~rich~) Date: Sun, Feb 3, 2008, 2:22am To: [email protected] Subject: wellbutrin xl... Hi...I take wellbutrin xl, 300 milligram and it iz working good... Yes the first 3 to 4 weeks yur body iz getting uze to the medicine, Dr informed me about this.. Same happened to me.. After about 4 weeks i noticed a big difference.... Yur body will get use to the medicine az i mentioned b4.. Hang in there.. It will get better after the 3 or 4 weeks. M 42 3 years
2/3/2008

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