SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  bi-polar/ phychosis weight gain due to cravings already described, really vivid nightmares,does knock me out pretty quickly. I was first diagnosed as bi-polare 16 yrs ago and have been on about every med you can think of. I'm currently taking depakot,sero,klonopin,and,invega. My symptoms have been pretty severe through the years ie, several hospitalizations a number of mania induced legal problems that sort of thing. I think that this med is very powerful effective for me but you should way this against the severity of your own symptoms.I can't see this as being the answer to insomnia, depresion,anxiety It just seems like overkill. M 32 3 months
2/4/2008
 4  Chronic, life-long insomnia I have not experienced the typical side-effects of weight gain or the other effects I've read about. I began with 50 mg dose at night, but I was sleeping 10-12 hours, so I cut the pills in half (12.5 mg) and that did the trick. I thought I had found the "Holy Grail" of sleep aids, since nothing had ever worked before. However, after about six months, the effects seemed to wane slightly. A couple of months ago, I began to have intermitten full-on panic attacks. At first, I thought it was stress from the holidays. But the panic attics continued and grew worse in January, and I began sleeping less. I'm beginning to fear that my body is becoming immune to the drug, and that the effects are changing from a positive sleep aid to a negative anxiety inducer. I mean, even trivial things were starting to just FREAK ME OUT, such as the thought of needing to affix the 2008 stickers to my automobile license plates or refilling my pets' food bowls. I tried going off it a couple of nights, but I flat-out could NOT sleep. I'm giving it a few more days, and then I'm calling the sleep clinic and asking to try something new. I would love to hear from anyone else who has experienced these symptoms. M 45 9 months
1/30/2008
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 4  OCD/GAD/Chronic Insomnia/Bi Polar Negatives: Carb craving/weight gain; restless legs syndrome; lack of drive; reduced libido; stuffy nose; reduced after several weeks of treatment. Positives: mood stabilized, anxiety greatly reduced without the use of Benzos, anger control, no nightmares, better quality of sleep, greatly reduced OCD/repetitive thoughts. I have been on Seroquel XR 400mg for about two weeks now and all of the above negative side effects have increased. I will be titrating myself back down to 300mg XR this week since the side effects were less intense with the same degree of positives (the RLS and lack of sex drive in particular). Definitely give this drug time to work, as the side effects do lessen over time after the first few weeks of treatment or dosage change. The weight gain is a problem, but drink a lot of water and excercise regularly and you can at least stop the weight gain. The XR does not give you as large of a rush when you first take it at night, works throughout the day to help with your disorders, and I recommend it over taking multiple doses throughout the day to avoid the up and down feeling. I definitely feel the benfits heavily outweigh the side effects once you are accustomed to how the medication affects you. Everyone around me has noticed how my behavior has greatly improved and I feel human M 33 3 months
1/28/2008
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 4  to correct a tic I developed worst side effect is difficulty in waking up in the morning. Also, I perspire in my feet and groin. Big upside is worth low downside, for me. M 55 4 months
2/5/2008
 4  Anxiety; Depression; Mood Swings Drowsiness; dizziness Love the drug; it has made me feel like a normal person again. I take Prozac as well as Seroquel in order to subside some of the violent mood swings one may experience as a side-effect of fluoxetine. Great medication; recomend it highly. M 25 2 months
2/9/2008
 4  depression/insomnia 200mg turned me into a zombie. Could barely walk to bed. Found that 50mg worked good. Takes me a long time to wake up in the morning. Only taking it because Ambien no longer worked for me. Guess this drug affects people differently. My wife was taking 200mg and had no trouble getting up and going to work. I wouldn't be able to function in the morning on that dose. M 66 5 days
1/6/2008
 4  Sleep disturbances I only like this stuff for sleep. It helps for that then completely wears off by the time it's time to get up. Taking this stuff during waking hours is not advisable due to a drunk like affect. If you want to read about my paranoid induced condition, I'm at (deleted - no longer exists) where you can read about my condition in the Interest Section. Be advised, this is a high-speed internet load & takes about 4 minutes with a 1.5 Mbps connection. My page also loads correctly with Firefox or Netscape. M 37 6 months
11/22/2007
 4  insomnia Unable to walk, talk, or move, but I did sleep for 14 hours straight. M 21 6 months
1/11/2008
 4   jerking movement off my jaw, drowsiness this stuff cured my drug induced psychosis, but i wonder if ill ever be able to live without this stuff. Its a pain to get off these types of psychiatric drugs. M 27 6 years
11/29/2007
 4  GAD, OCD & Depression Fatigue, hunger, twitching, chest pain, acid reflux If you can tolerate the numerous side effects, Seroquel is a potent anti-anxiety treatment, adjunct with other antidepressants and sleeping pill. Effective if you have severe anxiety disorders, treatment resistant depression and chronic insomnia. M 36 3 years
11/20/2007
 4  depression Sleepiness, lethargy Seroquel is a good medication if taken properly. It really helps me get a good night sleep and I dont wake up groggy. I take a very low dose, 25mg. I think the key with making this medication work is allowing enough time from the time one takes the medication to time of sleep. I usually take it 3 hours before I go to sleep and it kicks in at the right time. M 46 9 days
10/22/2007
 4  OCD, Insomnia Strange muscle feelings in legs about 1 hour after taking, hungry more often but no real weight gain due to strict dieting. Drowsiness the next morning. 200mg sometimes take 250mg, at night only. Also taking 300mg of Luvox which makes me not sleep but 4 hours at a time, this is why the Dr. is giving me the Seroquel. It also helps with my general anxiety and OCD related paranoia. M 35 5 months
11/4/2008
 4  Bipolar Disorder At first, like many, I had many of the bad side effects, the "Zombie" effects, I would zone out, if I would close my eyes, I would have nightmares in the middle of the day and couldn't think. I had my doc change the whole dosage to just nighttime, before I go to bed, that cleared up the daytime confusion, but for the first couple weeks, I still had very lucid nightmares. I didn't have weight gain (thank god, I had just lost a bunch of weight from a bad Zyprexa experience) Now I get a good 8 hours night sleep, my mood has definitely improved signifigantly, I still occasionally have a bad dream, but not nearly like when I started it. I would recommend hospitalization for when starting this medication to help get your body tritrated up to the proper dosage because of the signifigant side effects, especially if you live alone. When I first came home from the hospital, my wife had to walk me to the bathroom at night after I would take my meds, and would stay up to wake me if I The docs had started me on dosages in the morning, afternoon, and bedtime, which was keeping me a zombie all day, and I was stuttering, couldn't think clearly, if I would close my eyes, I would start 'soaring' and having very lucid daydreams like I was tripping. I told the doctor that I was unable to function as such and wanted the medicine all in the evening. M 38 3 months
9/18/2007
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 4  PTSD, Depression, Anxiety & OCD Major weight gain, memory loss only enough to annoy me when trying to think of things in the past, feel very groggy in the mornings Take 300mg before bed. M 24 3 years
11/1/2008
 4  Depression/Anxiety/Bipolar/PTSD When I first sought psychiatric care in 2002 I was a wreck. I will tell you that a Psychiatrist has to be advised of all goings on while taking the meds prescribed. I had my doses adjusted and the type of meds changed all based upon the results I experienced. Understand that sometimes I felt terrible only to have the meds stabilize after taking them for a while. Sometimes they stopped providing the desired results my Psychiatrist wanted. I am more stable now and remain so after all the adjustments. I take 100mg of Seroquel for sleep and to help organize my thoughts. It works for me. I agree that Seroquel gives me cravings but this is after about 30 min to an hour so I go to bed within that time frame to keep from eating. I also take 2mg of Gabitril 4 times a day for anxiety, mood swings and headaches. Twice a day I take 30mg of Cymbalta for depression and 200mg of Provigil twice a day for wakefulness. A .5mg Klonopin wafer 4 times a day helps to suppress my anxiety. I praise my Psychia At the direction of my Psychiatrist I went off of the Seroquel and tried lower levels than 100mg. With no Seroquel I could not fall asleep and I would lay in bed with all kind of thoughts racing through my head. With less than 100mg those symptoms went away but I would wake up and go back to sleep through out the night. It seems that 100mg is the magic number for me. M 58 5 years
6/24/2007
 4  insomnia Extreme hangover at doses higher than 25 mg, slight weight gain I find this helps my sleep patterns very much, I really never take more than a 10 to 12.5 mg dose and boy is that enough. If you like being a zombie....take a higher dose. I found it most effective at a very low dose. I go off and on it when i really find my sleep patterns are normal, but I am a 20 year insomniac. M 37 3 years
5/23/2007
 4  Schizoaffective(Depressive) No side effects really, other than when I was first taking it, it made me really tired. Was prescribed at night time. An increase in appetite, which wasn't necessarily a bad thing, since I could use some weight. But these side effects were only temporary and gradually went away after 3 - 4 weeks. Seroquel helped me a lot, it made my thoughts clearer and my thinking more organized. I've also noticed a decrease in auditory hallucinations now that I've been taking it quite awhile now(about 2 months). Less invasive thoughts. I take this in combination with wellbutrin, and I'm doing fine. M 18 2 months
6/2/2007
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 4  depression/sleep big doses made me have bad muscle spasms for few secs and walking zombie was taking 500mg day i dont take it anymore 4 deprresion because it screwed me up, i was taking 500mg a day then. just take it 4 sleep now and helps. cant believe its a anticrazy pill M 26 6 months
8/22/2007
 4  Mood d/o nos, anexiety, sleep the biggest one is weight gain, i have to take at least 600mg at bed time for it to work. I am currently trying to come off it, but my anexiety has been through the roof, and even 2mg of extended release xanax isnt working M 17 1.5 years
7/4/2007
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 4  Bipolar I I was prescribed 14 months ago Seroquel for suspected Bipolar I. I had always been pretty nuts before, paranoid, repetative thoughts, anxiety, suicidal one minute -- king of the world the next etc. I gained a significant amount of weight on this drug, but I had always been very thin before and like having the extra weight. I think it suits me. Though eventually had to throw away all of my clothes and buy bigger ones! The drug makes me feel very sleepy and after about an hour after taking it, I have to crawl (sometimes literaly) into bed. Other side effects are stuffy nose, having to remember to breathe which is very alarming and perhaps the worst thing are the palpatations, heart kicking around all over the place (I have been to casualty three times as I thought I was havig a heart attack). I have been under the cardiologist for just under a year and he didn't know what was wrong. Having read this message board it seems it could be Seroquel. I don't want to stop taking this drug, becau M 36 14 months
4/27/2007

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