SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  bipolar disorder nightmares, hangover in the morning which eases in 5 minutes with a cup of coffee. cognitive obtunding, i have no interest in the acedemic writing and reading i'd usually be enthusiastic about, no libido, completely uninterested in romance. i did have slight restless leg, weird uncomfortable feeling in hip joint but splitting the dose -300mg taken as 150mg .b.d. stopped that. i was regularly getting incarcerated in a horrible public psych ward with cruel staff against my will and was under threat of eviction due to manic behaviour, seroquel totally controls my symptoms which gives me security, i don't have to live in fear of the psych staff ringing the doorbell. previous regimens included several drugs, valproate + lamotrogine +rispiridone, horrible discomfort and side effects, life wasn't worth living. seroquel works for me on its own, i'm not on any other drug and since it doesn't physically hurt me like rispiridone did i'm willing to pay the price of the side effects i have in order to keep psych detention and eviction at bay. F 50 2 years
11/30/2009
 3  Sleep & Bi-Polar In less than a year, I've gained 50 pounds. I'm now experiencing serious holes in my memory - short term memory is shot. I gradually worked my way up to 300 mg each night. Told my doctor I no longer wanted to take it and he was adamant that I should continue with it. With the recent memory loss, I plan on telling him that I do not want to continue taking it. The only drawback is, that it's the ONLY medicine that's ever helped with my insomnia. F 55 1.3 years
4/15/2009
 3  bipolar affective pain in right breast, slight cognitive difficulty, some irritability at first, hair looking flat Psychiatrist started me on 50mg per day but I found that too much and even 25mg was too much so am taking 12.5mg at night now and my mental health is good at the moment. Also take 4mg of stelazine and one cap of lithium in morning. Baby doses of everything but the combo seems to be good at present. Don't like being on any drugs but I get in a real mess if I'm depressed. I work full time and I enjoy that. Not getting weight gain on smaller dose and it seems to be keeping me level. F 55 2 months
4/20/2009
 3  Bipolar 2 Severe muscle aches from my knee's down. Mostly at night. Cannot sleep. Feel like im in a fog. Still quick to anger. Not sure if I have given this med enough time its not been a week. I do have very pleasant dreams at night when I do get to sleep but am awaken from 1am til I get up every hour on the hour with muscle aches from my knee's down to my feet. Unsure why this is a side-effect. I too am drinking approx. 80-110 oz's of water daily and my keeping my caloric intake at approx. 1,200 calories. I am loosing weight, but just could be water retention being depleted. I feel like im "High" and also feel like im floating on a cloud but want to sleep. Will try this medicine for another week to see if side effects subside. Sex drive the same. Not effected. I am also taking Klonipin .5mgs in the am and at night. Doesnt seem to effect the seroquel. F 38 5 days
9/20/2008
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 3  Add-on for Bipolar NOS Hard to get by on less than 9 hours of sleep, sometimes very sludgy the next day, sometimes Seroquel and Focalin seemed to be duking it out. I was very VERY glad that I didn't gain any weight at all on this drug. It did bring me down from horrible mixed mania so that my problems were more within a tolerable level, did NOT make them go away, though. My pdoc actually wants me to get off of it and just stay on Lamictal and Focalin. The main problem, I think, is that Seroquel and Focalin sometimes play nice, and sometimes FIGHT with each other. They really do opposite things, one being a dopamine agonist and one an antagonist. Apparently Seroquel isn't *always* a dopamine antagonist, so I think the difficult times are when it's doing that more for whatever reason. Overall, not bad, but I've been on it long enough and I'm getting off with my pdoc's blessing. F 39 7 months
9/30/2008
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 3  bipolar 1 and anxiety w/ insomnia weight gain (22 lbs in 4 months)dry eye/mouth, constipation, hair loss, muscle and joint pain, elevated blood sugar, MUNCHIES. Feeling like one of the undead, trouble with my memory, stuttering, tremors in legs, and temperature control issues. After being on it for a little more than a year for mood stabilization and insomnia it dawned on me that there may be side effects other than the liver function studies the docs do every 6 months. I had been having all the above things going on and my general care primary doc was referring me to a rheumatologist for possible fibromyalgia when a-ha it is the stupid pills. Started weaning down and wonder of wonders, they are easing their grip!!! I use over the counter diphenihydromine sleep aids and Ativan to help with the withdrawl and smoke like a fiend for now. Smoking is temporary so no lectures and it does help and I don't drink or do illegal drugs so hold your horses. I had a brain tumor and many of the side effects mimicked lingering problems from the surgery to remove that and I thought the temp control thing was from hysterectomy. Hindsight is a wonderful thing, should be foresight if you are not psychic. Gotta laugh and stuff or you'll never stop crying! F 39 1.5 years
5/26/2009
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 3  OCD severe hair loss, some heart ache, palpitation works for ocd very well F 32 3 months
7/11/2009
 3  bipolar and insomnia extreme groginess in the morning, sleep walking (acording to my boyfriend), exhausted while awake, and feeling impared while driving in the morning I've been on seroquel for several years and I've started to realize that my sleep issues are probably do to it. It takes a couple hours for me to hear my alarm clock or a phone ringing right by my head. My boyfriend has noticed me thrashing in my sleep and getting up walking around several times in the middle of the night. When driving after waking up I don't feel in control of my truck. In high school I would have to slap myself on the way to sdchool so I didn't fall asleep while driving. On days that I can sleep in I will sleep 12 -16 hours and wake up, still feeling exhausted during the day. Seroquel has helped wiht moods but I'm not sure if the side effects are worth the reward F 19 4 years
6/21/2009
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 3  ocd, anxiety, sleep HAIR LOSS; sleepiness; groggy in the morning; some palpitation; extremely vivid dreams it helps with OCD, but you can't miss a dose. F 35 3 months
7/11/2009
 3  Bipolar Extreme somnolence, restless feet at night, lack of interest and pleasure, blunted emotions, panic attacks, steady weight gain regardless of food choices, temporary worsening of concurrent neuromuscular disease symptoms, gradually worsening memory problems. This drug is very effective in leveling mood (depending on the dose) and preventing psychotic symptoms. The steady weight gain has been horrible, and I've been placed on Actos to try to head off what my primary doctor terms "inevitable diabetes." The really big problem is I am no longer able to sleep at all without Seroquel. Nothing else works. F 35 5 years
8/30/2008
 3  Bipolar I have gained 35 pounds in 2 1/2 years. Also, I find it difficult to fall asleep without it. Seroquel works really well for my bipolar disorder, but the weight gain has been horrible. F 30 2.5 years
6/16/2008
 3  bipolar I On higher dose, rapid weight gain (from crazy sweet cravings) and major hair loss. Dry mouth and some confusion. I had been on this medicine at 25 mg dose in the a.m., 100 mg at night, for about 6 years, no problems besides some foggy-headedness. My pdoc took me off of lithobid and trileptal, and put me on lamictal. After about 10 months she increased my lamictal, added lexapro, and upped the seroquel to 200 mg at night. I started having these side effects, and she thought it was the lamictal. Told me to go off and she'd see me in a month! I don't think so! I didn't stop the lamictal, but ran into a snafu with insurance over seroquel. It's the best thing that could have happened. Within a week the cravings stopped and I could see a difference in my scalp! Not getting up in the night for drinks anymore, either. I just figured all this out today. Yay! F 21 7 years
2/21/2009
 3  Bi Polar Huge weight gain, muscle aches Works well for my moods, helps with sleep some, got to do something about the weight gain! 100lbs F 57 6 days
5/30/2008
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 3  Severe Insomnia Headache, nausea, decreased appetite, anxiety. I have only been on Seroquel for 2 weeks and it has greatly improved my sleep. Previously I would wake various times throughout the night but now sleep right through about 6-7 hours (could sleep more if I did not have to get up for work). Although I have been experiencing nausea in the mornings and some anxiety. Headaches have also been an issue. These side effects are nothing in comparision to not sleeping for 3 consecutive days and am so far pleased with the effects. I was initally worried about weight gain,but have noticed that when I take it at night (50-75 mg), I don't feel the urge to eat as I have with some other drugs (remeron) and fall asleep quite quickly. I am taking this in combination with temazepam which I am slowly wiening off of (terribly addictive drug with scary withdrawal symptoms). F 27 2 weeks
5/9/2008
 3  insomina, depression Vivid, violent dreams; grogginess next morning, feels like a zombie throughtout the day, carb cravings I'm currently taking zoloft for depression but Dr. switched me to Wellbutrin due to the side effects of zoloft. He also prescribed seroquel 100mg at night to help me sleep, as the wellbutrin will aggravate my insomina. Took the 100mgs and was still awake 2 hours later. Took another 100mg dose and 30 minutes later I demolished an entire bag of tortilla chips. Didn't notice til I got up the next moring that they were stale and 2 months past expiration date. Had some very disturbing dreams, scared me pretty bad. Getting up this morning was complete hell. Somehow managed to get kids to school and I'm currently at work suffering. When I first got to work spent the 1st hour staring at a tv that was not even turned on. Kind of a scary drug but it did help me sleep but the dreams were pretty bad. I dreamed that my 11 year old son attacked me so yeah that did not help my mood when I woke up. Think will keep tryin it for a bit longer see how it goes. F 29 2 days
3/11/2009
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 3  BP Difficult to rise in the morning. Sleep 9-10 hours. Thirsty. First two days felt drunk the next day. Forgetful on small details, which scares me a little. I am just in week 2. It has calmed me down. I have gotten a lot done at work as a result. I had a difficult thing to do this week and I was calm doing it, which is a real positive change. My Dr. suggested 50 mg, but I have only taken 25 mg and so glad I did. F 38 8 days
3/25/2009
 3  Bipolar mania/mixed episode Excessive sleeping, stuffed/bloody nose, next day drowsiness, massive weight gain, tardive dyskinesia, Withdrawal is HELL. Was really good for the first few weeks & snapped me out of a bad mixed/manic state within 2 days. At that time it saved my life. It only worked for about 5 weeks then just pooped out, but my psychiatrist wanted me to stay on it. Living on Seroquel is tough. You sleep all day, are drowsy and useless the next day, gain a lot of weight (40 pounds in 4 months for me, despite diet & exercise). I had terrible nasal congestion at night & not being able to breathe sent me into panic attacks. I eventually got tardive dyskinesia from it (manifesting in involuntary tongue movements, lip smacking & head twitches). Withdrawal is hell. Anxiety, agitation, hallucinations, headache, vomiting. This process cannot be rushed. I'd recommend this medication for SHORT-TERM emergency treatment of mania only. Schizophrenia is probably a different matter. F 37 4 months
3/10/2009
 3  insomnia WEIGHT GAIN: I've always had a steady weight of around 128-130 lbs. But since starting on seroquel, I've gained 45-50 lbs. Started around 20 lbs more after a month and steadily increasing as the months pass. Even if i exercise and diet, I can't seem to lose the weight. I'm still gaining more weight. I think this is the fattest I've ever been. I started with 1/2 of 25 mg tablet. I would immediately fall asleep with this dose. After 3 months, I couldn't go to sleep anymore. So, my doctor upped my meds to the whole 25 mg tab. Now, I notice it takes me longer and longer to fall asleep. Also, I get so very groggy in the morning. It's hard to concentrate. I feel kind of fuzzy. F 37 10 months
3/1/2009
 3  Severe Depression, Rumination, BPD Weight gain, involuntary muscle twitching, grogginess, feeling tired even after I'd slept 10+ hours, some short-term memory loss, heart palpitations. I first started taking this drug while in a hospital. I was not satisfied with this drug. If taken in the proper dosage, preferably smaller doses, in can be helpful but I don't think it is wise to take it for prolonged periods of time. I gained a significant amount of weight. For the first few months I took it it was very helpful. It helped with my mood and rumination in conjunction with prozac. I have found that it is overprescribed and that it should only be taken if absolutely necessary to avoid these side effects. I have been completely off of it for about 6 months and found most all my negative symptoms from the drug have disappeared. F 18 1.5 years
2/3/2009
 3  sleep hangover (at first); dehydrating; need to increase dose over time I began taking 25mg with 10mg of ambien (ambien made me hyper, binge, etc. and seroquel calmed the side effects of ambien) with hopes of quitting ambien. Initially knocked me out like a charm when taken 1 hour before bedtime, but now that i am quitting ambien (after 10 years) it doesnt seem to work as dramatically without it. Gave me a horrible hangover in the beginning that lasted all day, but seems better now (just hung over for 10 minutes). I eat less on seroquel alone than i did on ambien and seroquel combined. 50 mg will still knock me out but the hang over sucks and I dont want to get fat. F 31 1 years
12/18/2008

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