SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Not Sleeping Initially very hung over in the morning but that passed after a month. Still have the dreamy feeling and a little spaced out in the morning. I take 50mg at night and after about 45 minutes the wave of calm nothingness washes over me and I drift away. If anything happens after that I can’t remember it. I think seroquel is a very serious medicine. I also take 20mg of Lexapro and 4mg of Klonopin each day. I have been having trouble thinking and am wondering if the Seroquel is part of the problem. Thankfully I have spell check as my spelling is not as good as it once was. I am more calm and can relax better than before taking Seroquel. M 57 1 years
3/10/2009
 4  Off Label for Anxiety/Depression I started taking 50mg at night before bed two weeks ago. First night started at 100 and it knocked me flat out. Woke up with BP of 81/57 and thought something major was wrong. 2 weeks later I've still got a fair amount of fatigue and weakness as well as a major desire to do nothing but sleep! After the major side effects stopped, this drug in addition to 10mg of Lexapro has been a lifesaver. I was having MAJOR anxiety issues and thought that I was going to go totally crazy before getting on this medication. I'm really hopeful that the side effects will continue to lessen so I can get back to a normal day's activities without wanting to take a nap. This is much better however than wanting to die, so all in all I'll take it. M 28 2 weeks
3/14/2009
 4  Depression, Insomnia, BPD, OCD Weight loss; Crave carbs late pm; muscle spasms in legs after about an hour after taking it; short term memory loss and inability to multi-task like I used to; vivid dreams that mix with reality so I get confused about what I have said to whom; really hard to wake up once taken drug so hopefully no emergency arises; groggy and down in the mornings but not as bad; more headaches/migraines; gassiness; Nasal congestion 90 mins after taking it, so I snore!; low libido and sex is more painful because of the muscle contraction and dryness. Think I am going into early menopause which is unusual in my family. I thought we were having earth quakes the first few times I woke up after a few hours of taking it, by whole body was trembling. Find I am going through alot of pain killers for the headaches and sore legs etc. It helps me sleep soundly which is a god send, plus I am happier than I have been for the last 40 years. I am also mixing it with Lexapro 10mg (in mornings) M 42 2 years
1/23/2009
 4  sleep/depression/anxiety none I have trouble falling and stay asleep. when i try to sleep i have heavy rumination and it's difficult for me to even keep my eyes shut. I take 50mg and it doesn't even make me tried or drowsy; however, when i lay down on my bed and try to sleep, i am able to. I wake up the next day as any normal person. (side note: i slept for 6-8 hours). M 24 1 months
2/4/2009
 4  bipolar sideeffect when taking SSRI Wierd feelings at first like derealization, take at night and get me to sleep at first in 20 min. Now 1-2 hrs. Also had neck and back spasm when tried to increase dose to 150Mg went to emergency room as I couldnt move neck or back Dr. said reaction to seroquel he sees it all the time and gave me 5mg of Diazepam and a shot in butt of benadryl (50mg) told me to go back down to 100mg and take benadryl 50mg a day....spasms are a bad side effect scared I might have a spasm in heart muscle seroquel works pretty good on mood but sometime you still have mood break throughs M 41 6 months
2/4/2009
 4  bi-polar 2, insomnia extremely sedating (the reason I use it), hangover with significant irritability attached, carb cravings I have used seroquel very infrequently over the last 6 years until recently. I normally would only use it when I would start ramping up manic-wise which always results from sleep deprivation (more than 2 nights consecutively getting less than 2-4 hours each night) and would only require 25-50 mg to knock me out for a solid 8+ hours. I didn't like the side-effects so I'd rarely take it more than one night. Recently I've been battling depression insomnia, so I started taking very small amounts (10-15 mg) which seems to help me get a solid 5-8 hours so I'm keeping that up. I was previously taking temazepam but was concerned about addiction/rebound. Does anyone have any comments? (please email) ... specifically - a poster on here said that smaller amounts are known to cause greater sedative effects so to get less sedation but better positive effect take larger doses??? Sounds backwards to me and I could find no credible source information to support that statement. M 43 6 years
12/1/2008
 4  Depression, anxiety, rumination Only been on it for five days; started taking it in detox (alcohol). A week ago I felt like killing myself; now I'm a bit manic but basically in a good mood. I find it very speedy and can't take it at bedtime without sacrificing a night's sleep. May need to take a sleeping pill tonight. Don't know if it's a coincidence but my sex drive is off the charts. Don't know if I want it to be a coincidence either. I'm 45 and 17 was never as bad as this. Oh the other thing: I've gone from a pack-a-week smoking habit to a half pack a day. It makes cigarettes very satisfying. Makes my head a bit big and zoomy. I'm on 100mg a day--no way would I want a higher dose. OCD/Tourettic muttering rituals are down like the stock market. I like that. I'm cautiously optimistic. M 45 5 days
12/3/2008
 4  mood stability for sexual abuse hx I take 150mg/day. I get really restless legs and itchy skin. This drug has given me a lot of stability. I feel more like a normal human, more capable of handling stress, even happy. The benefits outweigh the side effects but I'd like to minimize them by taking 12.5mg regularly over the course of a day to total my current dose. M 45 4 months
12/24/2008
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 4  insomnia dry mouth i took 100mg right before bed and i fell asleep and didnt wake up for 16 hours. M 18 5 days
1/10/2009
 4  Bipolar/Impluse Control Disorder EXTREME grogginess, weight gain. However, it significantly slowed down my racing thoughts. But my biggest positive is that it gives me a quick "pause" to think before I act violently which I had so much trouble doing before I started taking it. When I first took Seroquel 4 years ago in the hospital, it nearly knocked me unconscious to the floor. I was taking 200mg at bedtime. I couldn't keep my head up. Usually happens an hour after taking it. The side effect feels as if my brain has a brick on top of it, and no matter how hard I TRY to think positively, there is a negative fog that clouds every thought I have. Usually all of this goes away after 2-3 hours, which is why I can only take it before bedtime. Recently, I relapsed and ended up back in the hospital because I stopped taking my meds. I now take smaller 50mg doses of Seroquel at morning and night. I do notice that the negative side-effect is not as severe. M 24 4 years
1/11/2009
 4  Anxiety, depression Lethargy, restless legs Ive recently cut my dose of seroquel down to 25mg from 50mg, and we cut my Remeron in half from 60mg to 30mg. It had to be done because i simply could not function on the higher doses. Would sleep for 10-12 hrs and still have a really hard time getting out of bed and leaving my house. So far so good on the smaller doses. M
11/18/2008
 4  Anxiety, Depression Initially, very sleepy. As I continued taking it weight gain (25-30 lbs on my 6' frame). It's worked great for me except the weight gain. I take 100 mg right before bed, read for 15-20 minutes and then I'm out like a light. Vivid dreams, but no bad ones. Wake up feeling great. M 47 3.5 years
11/20/2008
 4  bi-polar I sleep much better but I don't like some of the side effects the worst of which is the weight gain. I also experience dry mouth and my sinus's get blocked up, usually about an hr. after taking the medication. My mood has been much better since taking this medication. I am on a fairly high dose (600 mg.at bedtime) and I have recently had my dose reduced which has helped with the stuffy nose and dry mouth. Over all I believe the benefits outweigh the side effects. M 51 4 years
11/23/2008
 4  PTSD Weight gain. Fatigue - particularly in the A.M. I have a severely diminished sense of time passing. It helps with the worry, anxiety and feeling of doom - but at a price. I am on a very low dose but it seems to make me a bit "zoned out" - particularly time just passes without my taking any notice - I just think think to myself: "where did the day/night go? - how did it get to be 11:00 PM?" I've been given a second shot at life - I hate to think of it just passing by without me having the ability to appreciate it. Docs say the Seroquel has less severe side effects than other meds they could give me - it's all a balancing act: the horrors of PTSD or the side effects of the meds. I'll definitely take the sides! M 25 3 months
11/8/2008
 4  BP, Anxiety, Sleep, Withdrawals Always tired, couldn't wake up in the morning, weight gain, restless leg syndrome 1 1/2 hours after taking if I didn't fall asleep. I just want people to understand YES seroquel is a strong sedative. HOWEVER it DOES have use and many people benefit from it. These are people in the psychward. No this is not a joke. When I was there this stuff was handed out like candy. I had never even heard of it but I'd estimate at least 50-60% of people in there were on a certain dose. I knew this from when it was med time at night. It helped for schizophrenia, schizotypal, hallucinations, wasn't that great for the biplor patients but helped for the manic states, insomniacs (who were often depressed and tended to amplify depression but they were often put on other meds to combat it), extremely high BP that beta blockers alone couldn't lower, stopping seizures from withdrawal and psychosis. Most people gained weight while on it. Most people were in a perpetual sedated state. But the bad ones were the ones above 600-1200mg ed. In the ward is great for many reasons. But on the streets theres other better meds to take that don't work M 25 4 months
3/24/2008
 4  anxiety, panic disorder, sleep increased appetite not too bad though. drowsiness. Its a very good medication in my opinion. I just am now trying to get off of it due to the potential side effects. M 24 2 years
4/9/2008
 4  biplar disorder 1 I am from saudi arabia . seroquel was new here and i read about it and decided to try it > I experienced through manageable weight gain . sleepiness (6-9) hrs , red conjuctiva , immediate drowsiness after taking the current dose 500 mg once at night , feeling anxiety and dysphoric after the dose that got releived by klonopin 0.5 mg all together , sleeping like an infant , oversalivation during sleep that gone away after several months , rarely slurred speech that doesnt bother me . This magic drug stabilize me throgh the day like a Bible .. make it so bright for me not to slip ..raised my social status , improved my cognitive functions and increase my anger thresold dramatically ...finally it gave me the fourth dimension of thinking that i had been missing all my life as a messy untreated undiagnosed BP !now I got it why i had been called mad most of my previous time ! M 34 4 years
3/18/2008
 4  lamictal drug induced psychosis rapid heart beat, sedation lamictal gave me a psychosis, that means drug induced psychosis, what helped so far is abilify and seroquel. i am currently taking 100 mg twice a day for this condition, i will talk with my doc to increase to 200 mg, it has helped me but it has side effects M 14 days
2/23/2008
 4  Bipolar 2 crave carbs, pancakes,cookies cakes,but on 20lbs trying to eat the wright foods now after 9 months still trying to find the wright dose around 200-300 mgs a day M 49 9 months
3/1/2008
 4  Severe Anxiety/ Insomnia I have had some joint pain and have a hard time waking up in the morning. I use to workout in the morning but I cant make it to the gym anymore. I take between 25 and 50 mg, depending on what is going on in my life. I hate to admit that this drug has helped me, but it has helped me sleep and and control my anxiety. I am going to talk to my doctor about going off of this drug, to see what happens, because I just don't like taking drugs. I have started eating a raw foods diet to see how that impacts the way I feel. I did gain a little weight but have been trying to be smart about what I put into myself. M 49 6 months
1/4/2009
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