SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  BP,Rage,Depression,Bizarre thoughts A bit sleepy during the first month. Now taking 50mg morning, 50mg night. Started with 25, and went up from there until I felt good. Also take 300mg 5-HTP, 900mg St.John's Wort, 20mg Lithium Orotate. Seems to be a great, side-effect free cocktail. Great sleep, great dreams, much calmer and happier. Still enjoy life, but not worried about freaking out. Have been taking all the other things for about 2 years, but still needed something to "take the edge off" and Seroquel seems to be the answer. F 47 2 months
4/22/2009
 4  insomnia/depression/anxiety I take seroquel mainly for insomnia, I only take 25mg per night and that works great for me. I take 75mg of effexor per day too, in combination with 1.5 mg of clonazepam per day I am a far better person now. I am happy go lucky getting my sleep, not suffering with anxiety and am able to deal better with my life. You can get a little groggy in the morning, just make sure you leave 1o hrs aside for sleeping, this covers the hour you feel groggy in the morning. F 42 90 days
4/22/2009
 4  Bipolar and maybe something else?? Well, I've only been on Seroquel for a few weeks. I'm taking 100mg a night. At first it made my heart beat really fast as soon as I took it, annd it knocked me out for 12 hrs, still does it I take the full thing. I have noticed though that parts of my body twitch?? And this drug also can cause tardive dyskinesia( so guys be carefull ) My hand and fingers twitch, and I have noticed that my eye lid at one point.. So maybe they have to lower my dose? Anyways other then that it balances out my moods but just have to be careful with taking it regularly and drinking etc. Puts my deamons to sleep <3 :) lol F 21 3 weeks
1/6/2010
 4  Bipolar 1/Gen. Anxiety Disorder excessive sleeping, could sleep 12+ hours. withdrawl symptoms are terrible! This drug has been amazing. I also suffer from insomnia; and Seroquel, along with the Depakote puts me into a nice REM sleep. I'm easily affected by even the slightest change in dose though, which can throw off my sleeping pattern. Just make sure you don't take it too late or are taking too high of a mg at night time because it will knock you out. F 19 4 months
1/9/2010
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 4  Bipolar Depression / insomnia difficult to lose weight even while dieting, vivid dreams, and increased joint and muscle pain, even in my feet! I like Seroquel, because I can now sleep through the night at 50 mg Seroquel XR. Yes, I have vivid wierd dreams, but generally dont remember having them until I am trying to wake up the next a.m. For 6 years, I used to use a Tylenol PM for my insomnia. Tylenol PM can permanently hurt your liver, I think. I think using Seroquel is healthier than Tylenol PM. F 51 8 months
11/23/2009
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 4  Bi-polar disorder Slight weight gain, taken in conjunction with lithium. Intense grogginess and some unknown feelings of dread upon awakening. This passes as I arise and move about. I usually sleep at least 12 hours a night. Have been trying to awaken earlier, between 9&10AM by taking the drug at 7PM. Have some excessive muscle movements, and difficulty swallowing at night, which my doctor tells me could be a pre-cursor to Tardive Dyskenesia. I fear that, but am not ready to experiment with any of the newer classes of drugs for this disorder. I have Hyper-lipidemia have decided to take Niaspan (RX Niacin)in liew of statins. Not presently diagnosed with Diabetes, thankfully. I am a 62 year old female who has suffered with the symptoms of Bipolar Disorder for 40 years. I have a very strong family history of this disorder. The initial manifestation was about 4 months after the birth of my first child. It was in 1970 and was treated as Post Partum Depression. After moving about the country for the first 8 years of the onset of this disorder, I was formally diagnosed as having Bipolar Disorder. I was originally treated with major tranqualizors and was started on lithium in combo with antipsychotics and deseryl. In 2005 I moved to another state and my new doctor and I experimented with most of the usual antipsychotic drugs, all with disheartening side effects. About two years ago I was put on Seroquel and have taken as much as 600 mg in combo with smaller doses of lithium. I have recently decreased the dose of Seroquel to 450 mg and 300 mg of lithium. This combination seems to be working well for me and I am grateful for living in a time when these meds are so helpful. Hopefully, one day there will be a cure. F 62 2 years
10/23/2009
 4  insomnia, anxiety, depression a 'hungover' feeling the next day if i take it after 9.15pm the night before on 25mg and can fall asleep very easily with it so really great cure for insomnia F 23 2 months
12/9/2009
 4  BPD (bi polar) Crazy dreams, I wake up groggy, however the feeling passes with a few cups of coffee. Besides that all side effects are good ones so far. I feel happy able to play with my kids, laugh and work with a clear mind. Used to want to drink alchol every day most often apon first waking up in the morning, now I couldn't be bothered to. Will update as I continue taking this medication,so far it has been a wonder.. F 25 2 months
11/8/2009
 4  Insomnia/Racing Thoughts/OCD I take this because my mind cannot stop the chatter at night. I have taken 100 mg one hour before bed and it has worked well for four years without having to increase the dose. I do take Restoril 30 mg when needed, which is rare and usually due to occasional back pain. The sedation wears off by the time I wake up. F 45 4 years
11/11/2009
 4  Bi-polar constantly lethargic, sleeping upto 12 hours a day Has helped my mania tremendously. Just not sure how to stop sleeping so much. F 27 2 months
10/5/2009
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 4  Anxiety/depr./borderline dissociati Unfortunately, after about a year and a half of nearly miraculous help, I will need to stop this med because of uncontrollable weight gain, and concerns about diabetes, unless I can find a way to counteract the side effect. I understand that it changes the way the body metabolizes glucose. Diet change and exercise have not helped. After several years of uncontrollable anxiety and borderline dissociative episodes ( I felt like I was being possessed by a child-like part of myself, completely debilitating anxiety), and trying several different meds, having to detox off of addiction to benzos, which didnt completely cure me. then I was offered Seroquel, and I have felt better than I ever have in entire life. Have suffered low grade and sometimes more severe depression since a teen. This problem is genetic, at least 4 generations now. Unfortunately, it appears that the side effects are seriously dangerous to my health, with the possiblity of diabetes. I hope that I can find some alternative that works as well. I still recommend this medicine to anyone suffering severe uncontrollable anxiety and depression. It works different than other anti-depressants. Since I know how it works in the brain (what neurochemicals it affects) I can now go about finding a similar non-pharamceutical solution. F 48 1.5 years
9/26/2009
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 4  Bipolar Anyone who has had restless leg issues with seroquel have your doctor prescribe a low dose of requip and it will knock it right out. It is due to the dopamine blockade to which it is the weakest binding compared to others in its clas. This is actually not commom w/ seroquel but requip will get rid of it! F 42
8/4/2009
 4  Bipolar Mania, Anxiety, Insomnia * Twitching of hands involuntarily (not too often); forgetfulness of basic things; mild weight gain; heart palpitations at night - occurred 1 hour consistently after taking medication Overall, this medicine has worked wonders to help my anxiety/mania - I used to panic at the slightest thing, now it takes a very strong trigger to do it. It helps tremendously in the 'staying asleep' aspect, however, going to sleep is a bit of a nighmare because my heart feels like an electric shock 1 hour after taking medication. Only last about 5 - 10 minutes. F 30 2.5 years
9/5/2009
 4  Bipolar II, Acute Anxiety, Insomnia Deep sleep (Yay!), Moods (depression/hypomania) stabilized dramatically, INCREASED Libido, Increased Intensity of Orgasm(s). A little of my Hx: I'm a 26 y/o female, 5'2", 105 lbs. I've been seen/treated by many Psychiatrists and counselors since the age of 16 for Major Depressive Disorder, Acute Anxiety Disorder, and Chronic Insomnia. Over the years, I've taken every Antidepressant available (and combos of them), minus MAOI's - SSRI's all made the anxiety/insomnia worse and reduced my libido to 'nonexistent'; SNRI's worked for a while, then stopped being effective; Tricyclics made me sleep, but WAY too much - 18+ hrs q day; Atypical antidepressants just did NOT work for me. I finally got tired of "ping-ponging" from depression w/ suicidal ideation to 3-4 day episodes where I'd clean incessantly, not sleep, etc for those 72-96 hrs, and then crash back into the depression. I'm an RN, and several MD's I work with all highly recommended the same psychiatrist who's new to the area. I went into the first appt with a healthy skepticism - no one had ever helped me before, so why would this doctor be any different? WRONG! He was very thorough, thoughtful, and attentive. He Dx'ed me with Bipolar II (NOT Major Depressive Disorder) and agreed with the Acute Anxiety Disorder Dx. He rx'ed Seroquel 25mg HS (at bedtime), increased to 50mg HS week two IF NEEDED and Depakote ER 1000mg (and to continue Klonopin 1mg TID that I've been on since 1999). I've noticed a HUGE difference! I can sleep at night, my moods are stable, I feel better than I can ever remember feeling in my whole life! It's restored my sanity, my life, my marriage, my career, helps me enjoy my family, my 2-yr old daughter... I could go on and on! No weight gain or increased appetite, no hyperglycemia/diabetes, no increased cholesterol/triglycerides, etc. As I've researched Seroquel in the capacity of patient/RN, I've noticed that the VAST majority of patients who've had severe negative side effects from Seroquel are/were put on a grossly HIGH dosage, most not even titrated to that dose to see if a lower dose was adequate. I'm proof that, when given to the correct patient, wit F 26 3 months
9/9/2009
 4  Anxiety/Bipolar/Insomnia weight LOSS, vivid nightmares, extreme grogginess in the morning for the first 2 weeks where i had to stay in bed most of the day, now it's just grogginess in the AM that goes away after coffee and time, the worst side effect has definately been the nightmares. I see so many bad comments about seroquel, which I understand..it is a very strong drug and you should not be on it unless you have a serious problem. I feel like many of these comments are made by people who probably didn't need the drug. It has changed my life. I'm surviving and prior to Seroquel i was near the end. F 22 6 months
9/11/2009
 4  Mood swings, insomnia. Severe exhaustion, difficulty waking, grogginess, irritability, increased hunger. I was placed on Seroquel first, and experienced severe hunger and also exhaustion and difficulty waking, etc. Then I was placed on ADHD medication, Strattera, which causes a severe loss of appetite, so that fixed the hunger also. F 22 3 months
6/25/2009
 4   bi-polar Sleepiness is a big factor but i enjoy sleep and it doesn't get in the way too much. There is a slight increase in my appetite but I can easily control my hunger. The pill doesn't make you gain weight it's all about how you respond to your appetite. I am pretty satisfied with how it controlls my mood swings. I don't have my lows nearly as much as I used to. I would reccomend at least trying this medication. I almost didn't when i was reading posts on this website but i'm glad I did. Medication reacts differently to each and every person. If you have a problem with bi-polar the pros may greatly outway the cons. Good luck to everyone struggling. I know that this disorder is a bitch =) F 20 1 months
8/6/2009
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 4  extreme chronic long-term insomnia won't allow ADHD meds to work, makes me extremely hungry after taking it, causes or worsens depression, Regularly having full body feelings of extreme discomfort w/sick feelings after taking dose, impossible to wake up before noon the following day, cannot fall asleep & stay asleep without taking it, excellerated pounding heart & its rate, sleep eating at times, fast weight gain, withdrawals horrific accompanied with long period of suffering, etc...... My diagnosis' are PTSD, depression, general anxiety disorder, chronic extreme insomnia, & AD/HD. When I was a preteen, I had the HUGE misfortune of being misdiagnosed as being bipolar. I lived with this stigma up until a couple months ago, when I realized I was not bipolar ever, but had AD/HD since I was a child. Several times while growing up, I was made by my family & psych's to spend time in many psych wards. Nightmare! I was first prescribed Seroquel in 2002 for "bipolar possible psychotic" symptoms. I took it at night & all it did was help me get a good sleep every night. So, that is why I continued taking it nightly up until 2004. I stopped because I had to relocate, and the county's mental illness dept. I was going to for my mental illness' dropped me. Then in 2006, when my daughter was born, I immediately started receiving psych treatment again at the above place, because I suffered extensive postpartum depression. I was put on different cocktails of meds all the time, because none of them helped me what-so-ever. Out of all those many pills, the Seroquel was the only one I chose to keep taking. I divorced that last psych. last year, but I was prescribed 800mg Seroquel to take every night by bedtime, to treat my insomnia for almost 7 yrs. now. It is a blessing for me by helping relax my brain, allowing me to both fall asleep & stay asleep every night. I have been reading all over the web that only very small dosages help insomnia-I believe ar F 38 7 years
800 MG 1X day
7/21/2014
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 4  I am Bipolar who does not sleep I was perfectly happy with taking seroquel until my eye dr. told me that I now have cararacts I like so many others I do not sleep. I can't go to sleep. I lay there for hours on end. I have been known to stay awake and alert for 2 weeks at a time. My Psyc. put me on seroquel. we played with dosage, tweaked and added trazodone. I sleep better but still have nights where I only reach lala land. Yet I feel rested when I get up. Now I find out that I have caratacts caused by seroquel. I will have surgery to replace the lenses in my eyes. But what other drugs are out there to cause me to go to sleep? I've used lunesta and ambien with no effect. Has anyone tried some thing that even got close? F 50 4.5 years
1/14/2010
 4  Depression, anxiety, suicidal ideat Extremely drowsy in the morning it I don't get 8-10 hrs of sleep. Dry mouth. I'm 34 but feel like I'm 90 after taking this med for 3 weeks. Doesn't matter if I do anything strenuous or sit around all day. My whole body hurts. My depression, anxiety has toned down alot since taking it. F 34 1 months
150
6/1/2016

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