OMEPRAZOLE Reviews (OMEPRAZOLE)

Average Rating: 1.5 (238 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

OMEPRAZOLE  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). If you are self-treating with this medication, over-the-counter omeprazole products are used to treat frequent heartburn (occurring 2 or more days a week). Since it may take 1 to 4 days to have full effect, these products do not relieve heartburn right away. For over-the-counter products, carefully read the package instructions to make sure the product is right for you. Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar brand names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.   (Sources: U.S. Centers for Medicare Services, FDA) FDA Approval Date: 2009-01-21

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR OMEPRAZOLECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Previous ulcer Pain and grumbling in lower left region of body in abdominal/groin area mainly starts up in the morning area and usually swollen tummy. I've been years on omaprazole 20mg but during treatment in hospital I was on 40mg but only for a limited time and told to stop 40mg then and go back to 20mg twice daily . F 71 7 days
20mg/40mg 2X day
5/21/2026
Email
 1  ACID REFLUX I'm no longer taking this medication. as a result of depleting vitamin B12 which I was taking everyday as a chewable lozenge, and magnesium for nightly leg cramps, my feet and lower legs and finger tips were getting numb and tingly, This would dissipate over a day or two. Did not make a bowel movement every day, digestion was slowed down. Normally I would have bowel movement everyday. Less urination noticed. shooting pings of pain in the stomach during the day from mild to uncomfortable at night time, where it would keep me awake, pains on the side of the stomach and in the back always at nighttime laying down to sleep. F 64 12 days
20 mg 2X day
6/22/2025
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Patient History
 1  was misdiagnosed with chronic gerd nausea, vomiting, diarrhea, anxiety, panic attacks, dizziness and drunklike feelings, feeling of impending doom, thoughts such as "what if I die or something bad happens to me" Stopped taking Omeprazole December 20th 2024. It is now June 7th 2025. Still have lingering symptoms, mild situational anxiety, nervousness that feels like it comes from my stomach, stomach butterflies especially before i go out somewhere, mild afternoon fatigue, sometimes fatigue in the mornings, sometimes slight dizziness and slight headache. Going to the farm and spending time with horses seems to also help. M 42 64 days
40mg 1X day
6/7/2025
Email
 1  Stomach pain Good lord where do I even start. Was prescribed for stomach pain. I had 3 good days on it and by day 4 all hell broke lose. Severe panic/anxiety attacks during middle of night followed by hot flashes dry heaving/vomitting, neck pain, fuzzy foggy head feeling, fatigue, felt like I had a severe case of the flu with a heavy dose of brain confusion. Oh and the headaches that morphed into a terrible migraine. Never had a migraine in my life. On it 15 days total. By the way completely healthy woman in my late 30’s, daily runner, currently trying to muster up the strength to walk to my mailbox. No way in hell would I recommend this drug. Praying I'm on the road to healing. I can deal with anything but brain fog. F 37 15 days
20mg 1X day
4/23/2025
Email
 1  Possible ulcer/stomach pains Anxitey,fatigue,insomnia,nausea,vomitting,constipation plenty of more I probably can't think of atm. This poison just added to an already horrible situation.Hopefully because I only did six days recovery won't be too bad struggling with gut issues still 2 days off of it trying to stay hopeful. Do your research don't just take drugs dr give to you be your own advocate listen to your body. F 30 6 days
40 1X day
4/2/2025
 1  My doctor and I thought I had GERD I'm no longer taking this medication. Stomach pains and cramps, fatigue, strange dreams at night, unexplained sadness, fear, feeling of impending doom, anxiety, dizziness, weakness and feeling I might pass out, depression, loss of interest in activities, mild headaches, nausea, vomiting, and diarrhea M 42 64 days
40MG 1X day
3/24/2025
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Patient History
 1  Acid reflux Heightened anxiety/depression (that are pre-existent) And other symptoms already mentioned...blurry vision,stiff neck,etc... It's way outdated and should be banned from market... M 43 12 days
20MG 1X day
1/9/2025
Email
 1  Acid reflux Depression, shoulder pain, pins and needles down arm, tinnitus, anxiety insomnia, no appetite, feeling of doom and gloom and feeling of panic I had acid reflux so the doc give omeprazole whitch did help my reflux. But soon as I finished the course the withdrawal was pure hell!, the depression was really bad with no sleep and no appetite with high anxiety. I really thought I was going nuts but exicise helped me through it, done swimming walking cycling and it helped me big time. You gotta drive it out of your system and will get better. It took me 8 to 9 months to feel ok again but still got tinnitus. I WILL NEVER TAKE OMEPRAZOLE AGAIN doctors dont want to know so be careful. M 62 4 weeks
20 1X day
12/30/2024
Email
 1  Acid reflux Severe depression, feelings of doom, bouts of anxiety, feeling of fullness w/ no appetite, eye twitch, head doggies, eye floaters and blurred vision, tinnitus, rib pain on both sides and upper rib cage on right side, gastrointestinal issues including watery explosive diarrhea, weight loss This has been a horrific experience! I decided to use an off brand 14-day course of omeprazole after I noticed some burning on my left sternum area. I had been prescribed omeprazole in the past for acid reflux without any issues so I figured it was safe to use the OTC version for a short course. WAS I EVER WRONG!! This has been a nightmare since the first day. I am a pretty stable person and generally don’t experience depression or have anxiety but that was the first side effect I noticed. I was so depressed and couldn’t pull myself out of it or understand it. Then bouts of intermittent anxiety. My stomach felt full even though I hadn’t eaten and I lost my appetite and started losing weight. I then started with rib pain on both sides and under the top right rib cage. I have also had middle back and neck pain as well as right back pain that mimics a pulled muscle. The tinnitus was another issue and my right ear was blocked too. I developed a health anxiety that I’m still struggling with now with fear and panic that I have some serious disease. The gastrointestinal issues are continuing as well like I have IBS or something similar. I tried to figure out what was happening and realized all of this started with the omeprazole so I decided to look up patient reviews and found this forum which helped me to know others were describing the same symptoms. I stopped after 11 doses and things seemed to improve. F 63 11 days
20 1X day
11/19/2024
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 1  GERD Muscle twitches, vibrations/buzzing in pelvic area and backside, joint pain. I am living a nightmare. I am even going to see a neurologist, anyone else have the same issues as me? Please email me. Thanks F 62 5 years
40 1X day
8/1/2024
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 1  Indigestion, acid reflux, globus Day 1 - severe dizziness, chills, back and shoulder ache, migraine, metallic taste in mouth, stomach felt sour, zero appetite, heart palpitations. Day 2 - nausea that developed into really violent vomiting and dry hacking when there was nothing else to vomit, zero appetite, chills and tremors - whole body shaking, hands and feet icy - dizziness, metallic taste in mouth, dull pain in back and shoulder, stomach felt sour and queasy. Day 3 - discontinued. Felt lightheaded, very weak, huge headaches, stomach lurched from bubbling to growling, continued burping and a little dry heaving. Before I took this poison, I had a feeling of something stuck in my throat. I was told it was Globus. However after the second day of vomiting the contents of my stomach out, whatever was stuck in my throat has gone, so maybe it wasn't a feeling at all. Anyway, please ASK your GP for alternative methods and medications for treating acid reflux and indigestion first before plunging straight to this very powerful medication that I think should only be prescribed as a very last resort. I will say that my heartburn has lessened somewhat but perhaps I would have had the same result if I stuck to gentler antacids and diet changes. F 54 2 days
20 mg 1X day
6/10/2024
 1  Gerd Absolutely awful headaches no energy shakes lower back pain made my stomach worse cramps bloating and burning looked up reviews so I decide to stop that was only 2 days ago stomach calmed down lower back pain easing still got headaches and extremely tired started to eat a bit better , Would never take again F 60 0 weeks
20 1X day
5/28/2024
Email
 1  GERD/LPR Headache, increased anxiety/sense of impending doom, heaviness in head, body aches, heart palpitations, increased pressure in ears Avoid! GI doctor put me on this to prep for an endoscopy. Only made it six days before I had to stop taking it. Awful headaches, heaviness feeling in head, and overall feeling of being unwell. Could feel my heart pounding. Insane increase in anxiety - I typically have anxiety, but I felt scared and on the verge of tears constantly. Never again. F 32 6 days
40 MG 1X day
2/22/2024
 1  Gerd Back pain legs pain anxiety and panic attacks cannot do anything really tired all the time stopped theses 8 days ago still feeling awful Do not take F 62
20mg 1X day
12/27/2023
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Patient History
 1  Acid reflux This drug depletes your calcium potassium magnesium to a very dangerous level I was admitted into hospital becouse of this horrible drug and I am still suffering today because of it This drug needs to be taken off the market immediately M 12 years
20 mg 1X day
11/9/2023
Email
 1  Heart burn, burning throat Serious leg and foot pain. Chest discomfort and pain. Constipation, dry cough and headache. Feeling depressed and eye twitching. This drug has serious side effects. I can't believe it's still on the market. There are people who will continue to take this and not know it is the cause of their systoms. 61 14 days
20 mg 1X day
9/17/2023
 1  GERD gadtrotis Scared to take this. Pantaprozole left me with symptoms of dx I did not have before starting med. Feeling of feeling puffed all over wo to h the worst joint stiffness ever in my life pain included. Doc changed rx to Omeprazole. HMMMMMM. F 66 1 days
40mg 1X day
8/12/2023
 1  Ulcers/Hiatal Hernia Headaches, dizziness, increased joint pain, nausea, random chest pains, bloodshot eyes, sense of hopelessness and fear. I can't take this anymore. I keep trying to take this medication having to stop and start again because of side effects. This last time I took for 16 days and last 5 days feeling very ill. Woke up this morning after restless night crying, “I'm going to die”! I kept trying to stick with this because I had to be treated for severe anemia caused by my then unknown ulcers. Reading other people's experiences lets me know I'm not crazy. I'm not taking this poison again! F 62 16 days
40MG 1X day
6/17/2023
 1  Gastritis Oh my goodness uncontrollable anxiety very upset crying very low nausea never again terrible drug hope it goes away soon F 76 3 days
10mg 1X day
6/6/2023
 5  Acid Reflux No side effects. I started with Prilosec then switched to prescription Omeprazole. I have had no issues with this drug.I don't know how so many people rated Omeprazole so low. M 67 40 years
20MG 1X day
5/31/2023
  

OMEPRAZOLE  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). If you are self-treating with this medication, over-the-counter omeprazole products are used to treat frequent heartburn (occurring 2 or more days a week). Since it may take 1 to 4 days to have full effect, these products do not relieve heartburn right away. For over-the-counter products, carefully read the package instructions to make sure the product is right for you. Check the ingredients on the label even if you have used the product before. The manufacturer may have changed the ingredients. Also, products with similar brand names may contain different ingredients meant for different purposes. Taking the wrong product could harm you.   (Sources: U.S. Centers for Medicare Services, FDA) FDA Approval Date: 2009-01-21

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