SPIRONOLACTONE Reviews (SPIRONOLACTONE)

Average Rating: 2.4 (268 Ratings)

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 DIURETICS ALDOSTERONE RECEPTOR ANTAGONISTS

 Type: Rx Drug

  

SPIRONOLACTONE  (SPIRONOLACTONE):  Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone). Spironolactone is known as a "water pill" (potassium-sparing diuretic).   FDA Approval Date: 1999-07-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SPIRONOLACTONE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SPIRONOLACTONECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  PCOS Dizziness, heart palpitations, tachycardia, difficulty concentrating, chest tightness, shallow breaths, hot flashes, panic attacks I got really dizzy taking just 25mg dose, took a while to adjust. Once I did I felt ok and at first it seemed like a miracle pill for PCOS. My back and chin acne cleared up, I grew more hair on my head and less on my body, no longer had water retention. After a couple of months I noticed myself having heart palps. When I started working out again my heart was jumping up to 216bpm and while doing something so simple such as putting shoes on I would get a heart palp. I talked to my doctor and he assumed it's because I gained weight and was out of shape but sent me to a cardiologist as a precaution. After wearing a holter, doing an echocardiogram and stress test it was determined my heart is strong and in good shape. They chalked it up to anxiety. The palps continued to get worse despite me eating more healthy, hydrating and getting more in shape. I had this moment where I realized it's possibly the Spironolactone. As soon as I stopped it within 2 days my resting heart rate went down by like 30 bpm. It doesn't end there. I tried stopping abruptly as the pharmacist said it was ok as it's just 25mg, I got super sick. So dizzy I couldn't walk or drive. I was immediately put back on it by an emergency after hours doc who had me cut the dose to 12.5mg and now I'm down to half of that. I can hardly wait to get off it completely. It has basically made this last F 36 1 years
25mg 1X day
8/7/2022
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 2  Acne Larger breast, sexual thoughts, hyper sexuality, extreme brain fog, confusion, depression Helped my acne , ruined my life F 43 1 months
1X day
7/27/2022
 1  Hormonal Acne Chest Heaviness, Anxiety, Panic Attacks, Depression , Fits of Crying, Enlarged Breasts, Multiple Menstrual Cycles, Mental Instability. Spironolactone is an incredibly harsh and risky drug to take for hormonal acne. Had I known all of the adverse effects of this drug, I would've ran far from it! Don't even consider spironolactone, the issues associated with it are not worth it! F 25 2 years
150 MG 1X day
7/23/2022
 1  Edema lower legs This should be taken off the market!! Within days my legs felt like my lead and started cramping up so bad I could barely walk. Upset stomach and overall unsteadiness and awful feeling. I tolerate medication well but this by far was the worst. I found other ways to reduce the Adema with some exercises and lymphatic massages which helped wonderfully Please be very careful with this med. I had this reaction by only taking half of a 25 mg pill daily which amounted to 12.5 mg I can only imagine if I took the whole thing what a nightmare that would have been F 5 days
12.5mg 1X day
7/12/2022
 2  Hidradenitis suppurativa Anxiety, loss of period, stomach swelling, back pain, dizziness. Let me preface this by saying I've tried this medication twice and stopped taking it the first time due to a loss of my period which caused other issues. The second time I stuck with it. It cleared my HS until I was about 8 months in then had breakout after breakout and it stopped working. For that--then I lost my period for months and looked pregnant. Do NOT drink with the med and if you do limit your alcohol consumption. I ended up with no tolerance to alcohol. I also had no idea this is why my anxiety increased to an unmanageable level. It's been 3 days since being off and while my head is clearing I've gained 5lbs. F 39 1 years
50MG 2X day
7/1/2022
 2  Androgenic Alopecia Gained a lot of weight around my mid-section that I just cannot shift, no matter how much I diet and exercise. Although I have never been a "skinny" person, I always carried my weight around my bottom half. Now I've got a belly I never had. Lost a lot of muscle mass and find it very very hard to tone or build muscle through exercise. Hair and scalp less greasy/irritated. Skin clearer, although it was never bad. Urinating a lot. Blurred vision. Feel like my hair hasn't got thicker but it seems to have stopped some of the shedding. I stopped the medication for a month whilst I froze my eggs and I had way more shedding than that I have ever had before the medication. Looks like I am stuck on this medication now! F 32 18 months
200mg 1X day
6/23/2022
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 2  Hormonal acne Minimal effect on my skin but total of 15lbs weight gain (I count macros, work out religiously) and menstrual changes (breakthrough bleeding often followed by amenorrhea). Fatigue easy, exertional HR much higher. F 39 1 years
50-100mg 1X day
6/16/2022
 3  Acne Restless sleep, trouble falling asleep, chest pain, anxiety, panic attacks I wish I knew sooner the mental side effects of this medication. My dermatologist prescribed it without ease not making me think of possible precautions. I struggle with anxiety in my adolescent life, but this medication brought out the worst of my mental health- unexplainable panic attacks making me unable to take a full breath while my entire body gets numb. The first side effect was not being able to fall asleep at night after closing my eyes for 2-3 hours. This extra restlessness/anxiety/panic disorder created sever bags under my eyes and non-needed chest pain. This medication should be taken off the market and EVERY doctor should fully tell their patients the side effects- mental or physical. F 22 4 months
50 1X day
6/8/2022
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 5   Nipples are sore and I urinate a lot. I take spironolactone as a anti androgen. I take the medicine as part of my gender affirming Hormone Therapy. Any questions or comments please contact me M 50 3 months
100 2X day
5/29/2022
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 3  Acne Anxiety, panic attacks, voice changes Spironolactone helped very nicely to reduce my acne & I see a huge difference within my skin after taking it for 6 months. However my doctor upped my dose from 50 mg to 75 mg and that's when the anxiety began. I'm a singer and my voice has been cracking and I have no control over it. Another thing is I tend to get very nervous about little things like speaking to friends or family or ordering through the drive thru. I've performed in front of 100+ people no problem, and having this issue is making my life so much harder. I'm going to decrease my intake and see if that helps. But im going to take a two week break first. Take this pill with caution and ask your doctor to put you on a very low dosage first. I could only imagine immediately starting at 100 mg or higher. F 21 6 days
75 1X day
5/15/2022
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 1  Blood pressure Side effects were extreme anxiety, panic and fatigue. Did nothing to lower blood pressure. I haven't taken it in 2 weeks and I'm still getting waves of panic, which I've never had before. F 50 5 days
25mg 1X day
5/6/2022
 1  improve hair + mild acne severe mental issues, panic attacks, anxiety, depression, 10 lb weight gain, mental confusion, thinning face skin, large eye bags, rapid aging face, red face, hot face, dizziness, fatigue, large breasts, no period, no sex drive that list is my experience with Spiro. after stopping the drug 4 months now, the negative side effects are slowing fading but not gone by any means. look up the side effects for low testosterone and that is spirolactone. it basically cancels all your androgens in your body. you get fat, feel depressed but have clear skin. THIS IS WHAT CAN HELP ! for the thinning facial skin : start rubbing DHEA on your face, you can buy a tropical cream on amazon. drink lemon water and or beetroot juice. take lots of vitamin D. take NAC to detox. F 47 3 months
100mg 1X day
5/3/2022
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 1  Low Potassium Anxiety feeling light headed insomnia crying..moody..I am usually a very cheerful person no appetite at times Calling my Dr tomorrow not taking it any more I was fine before I took this! F 65 0 months
25mg 1X day
4/17/2022
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 1  Hormonal Acne I was taking spirio for my hormonal acne. I have never dealt with depression because I am usually a happy person but I was feeling so depressed ed I didn't want to go out side I didn't want to eat and I would have extreme anxiety attacks I was scared to go to sleep because thats when my anxiety attacks would come the most. I have dealt with anxiety but never like that. I also had very disturbing thoughts that were uncomfortable. I saw that someone was also having that problem while taking spiro. I felt so horrible when I was taking this I was a mess, and I did not feel like myself. I did I not have these symptoms immediately, they started to kick in about 2 weeks later after starting the medication. But when I stopped taking it, it took about 2-3 days for it to get out of my system but I was feeling much better! It's been 1 week and I haven't have anxiety attack or any of my other symptoms. Just drink a lot of water to wash it out of your body. I understand that not everyone has symptoms but if you are having any of these please STOP taking this medication. Also I would like to add that I did not see any results for my acne it was still that same F 17 28 days
50MG 1X day
3/31/2022
 5  Acne, Hair loss All positive side-effects. Acne and hair loss stopped. Mood stabalized. Period disappeared. Minor breast size increase. F 35 18 months
200 1X day
3/29/2022
 1  Hormonal Acne Depression Do not take this pill. it left me severely depressed and feeling hopeless. F 14 12 months
100 MG 1X day
3/2/2022
 1  Hair Heart palpitations, nausea, heart race, anxiety and panic attack, short of breathe Do not take. I was perfectly fine and healthy before taking this. It was the worst time of my life while on it. F 46 6 months
100mg 1X day
2/17/2022
 1  Unwanted facial hair Experienced extreme anxiety and panic attacks. It is important to note that I am also taking Sertraline and have been for several years. I am not sure if there was a drug interaction or if this was strictly from the spironolactone, but I am very thankful I found this website as I began to research why I was mentally and emotionally falling apart after 2-3 weeks of taking this drug. Aside from the anxiety, I also experienced uncontrollable negative and fearful thoughts that consumed me day and night. I immediately stopped taking the drug upon reading similar reviews to what I was experiencing. Within a day or two of stopping there was a noticeable difference in my mental and emotional state. I have been off for a month now and feel like my normal self. This was one of the scariest things I have ever dealt with regarding my well-being. I was well on my way to having a nervous breakdown and having to be hospitalized. If you are on any medication for anxiety or depression, I would be extremely cautious regarding the use of this drug. F 53 1 months
50 1X day
1/28/2022
 1  Acne Anxiety, panic attack, fainting, dizziness, slurred speech, headaches, loss of concentration, eyesight issues This is the worst medication I have ever taken in my life! I only took it for 4 days before I collapsed at work, it's been 4 weeks since I stopped taking the meds and I have the worst anxiety and panic attacks constantly, before taking the meds I would have small episodes of anxiety but they would easily pass. I have been to my gp repeatedly to try and fix this but I don't know how. If anyone has any tips please get in touch. F 30 4 days
50mg 1X day
1/26/2022
Email
 2  Primary Aldosteronism It worked to bring blood pressure down however fatigue, sleepiness, leg and feet cramps daily including at night became unbearable. Got eye twitching, trouble sleeping and dehydration if I sweated. It was hard work trying to keep electrolytes balanced. I Have felt my moods a bit flat as I am normally a happy chirpy person. The good part is I have healed from primary Aldosteronism and have come of this drug! I’m 3 weeks off it, but still have a few fatigue side effects. I am glad to have no more severe cramps!!! Drugs are good for emergency use but it is good to understand how we got unhealthy in the first place ie body, mind, spirit and diet adjustments. I find herbs are a good support. I had asthma before and adjustment to my mind, diet and emotionas cured it. F 58 2 years
50mg 1X day
1/19/2022

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