SPIRONOLACTONE Reviews (SPIRONOLACTONE)

Average Rating: 2.4 (268 Ratings)

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 DIURETICS ALDOSTERONE RECEPTOR ANTAGONISTS

 Type: Rx Drug

  

SPIRONOLACTONE  (SPIRONOLACTONE):  Spironolactone is used to treat high blood pressure and heart failure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. It is also used to treat swelling (edema) caused by certain conditions (such as heart failure, liver disease) by removing excess fluid and improving symptoms such as breathing problems. This medication is also used to treat low potassium levels and conditions in which the body is making too much of a natural chemical (aldosterone). Spironolactone is known as a "water pill" (potassium-sparing diuretic).   FDA Approval Date: 1999-07-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SPIRONOLACTONE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SPIRONOLACTONECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Oily skin,acne,clogged pores Skin seems suddenly more saggy and loose on body, but may be unrelated. F 58 120 days
50 MG 2X day
7/9/2014
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 4  PCOS Hair Loss, slight bloating Period spotting. especially cold in my extremities in winter. slight weight loss, clear skin. unsure about hair growth at the moment but hoping that it will grow. F 18 3 months
50mg 1X day
7/3/2014
 4  PCOS, absent periods Frequency urination, weight loss, nausea, dizziness, reduced hair growth on chin, legs, and underarms! I started taking 25mg twice a day for PCOS. I had high testosterone levels, abnormal hair growth, and acne. My doctors continuously did blood work every three months to see how the medication was working. I was increased to 50mg 2x a day then eventually to 100mg 2x a day. I did not notice side effects until 100mg aside from weight loss, I lost 10 pounds overall without doing anything different. At 100mg my testosterone levels were still very high and we tried a few different birth control pills. Levels were consistent for the next two visits and it was decided to decrease to 75mg. Currently I do not have any cysts so my doctor decided to try taking me off the birth control pill and reducing to 50mg 2x a day. I have magically gained 8 pounds in the last week and am unsure if the two are related. I am thinking since I am still consuming the same amount of water and do not have the higher strength of the pill to act as a diuretic, it is water weight. F 26 2 years
50 MG 2X day
12/5/2013
 3  Acne Night sweats if I work out during the day, body acne (when I had none before), and I seem to be gaining weight and I always feel bloated. Will try to update in a month to see if I really am gaining weight from this pill. Not looking good. Oh something else - about the same time that I started this pill (and Aczone), I developed Keratosis Pilaris (chronic skin condition) which was pretty devastating. I know the skin condition is genetic but it is weird it happened at the same time I started this acne medication. I take this in addition to Aczone (topical treatment). The Aczone seems to prevent the little ones and the Spironolactone helps with the cyst type acne. Spironolactone seemed to work right away. I call it my miracle pill! 22 years of acne finally GONE. But the side effects may be too much for me to handle. F 36 3 months
50 MG 1X day
10/22/2013
Patient History
 5  cystic acne Frequent urination, weight loss, missed periods, possible anxiety, dry mouth at times. It was a pain to have to go to the bathroom all the time, but I loved that I shed tons of water weight and felt much more comfortable with my weight. Not certain if the anxiety was because of the drug. Really liked it overall and made my cystic acne go away almost completely. F 33 9 months
50mg 1X day
10/8/2013
 3  acne Dizziness, headaches, dry eye, clogged meibomian glands I started on 25/day. Had dizziness, headaches. A month ago I was increased to 2X/day and within a week my eyes hurt horribly. The oil glands in my eyes are completely clogged. I just read that spiro can cause MGD because your oil glands need the androgens. F 43 4 months
25mg 2X day
10/2/2013
 1  Hair growth on face & loss on head This caused me extreme grief. I desperately wanted to stay on it to help with my problem. I developed shooting pain behind one of my nipples. Due to its name "spironalactone", I wondered if the "lact" portion of the word had anything to do with the breasts. On a hunch, I stopped the drug. Breast pain checked out fine with a mammogram and subsided so I resumed the meds. About 2 months later the pain came back and I developed the most insanely itching and burning face, neck and chest very little redness but oh the pain. It feels like stinging nettles...or razor burn. Anyway it started in my cheeks and gradually lowered into my chin, neck and chest and now my arms too. I've been off of the drug for about 10 days now and the breast pain has once again let up but this itching is driving me mad. I hope it doesn't last much longer. The odd thing is that there's hardly a mark. Slight redness but its horrific. I'm rubbing 2.5% cortisone on it and taking allergy pills but the only thing that helps is Ice. :( F 46 8 months
25mg
9/30/2013
 3  weight gain persistent nausea,extreme fatigue,irregular heart beats,headache,dizziness F 24 1 weeks
25 mg
7/31/2013
 5  water retension and high blood pres Urination cotton mouth occasionally M 49 6 months
50 mg
6/24/2013
 2  Acne Nausea, light headedness, fainting spell, leg cramps My doctor did review blood work before prescribing. I typically have low blood pressure any way. Was very careful to increase fluid intake. Woke up from a leg cramp at night and ended up with a scary fainting spell. Stopped taking the medication but have periodic spells of nausea, almost anxiety, since stopping. This probably would have been beneficial for my acne, but I don't like feeling like I could pass out at irregular times. Hopefully my system will get back to normal soon. F 41 12 days
25 1X day
5/6/2013
 4  Hormonal Cystic Acne Irregular menstrual cycle at higher doses (>100 mg). I was getting cystic acne on my chin and cheeks every month around my menstrual cycle. These cysts were huge and would last for 1-2 months. Spironolactone helped me get my hormonal cystic acne under control but, after around 8 months, I started getting cysts on my chin (no more on my cheeks) again. I tried increasing my dose but this really messed my period up. I took a dose of accutane in college that really helped me so I stopped the spiro and am currently giving accutane another shot. I probably would not have gone on accutane if spiro could have kept the cysts suppressed. Overall, this drug helped me and I would recommend it to other women who struggle with hormonal acne. F 31 1 years
50 mg 2X day
4/13/2013
 4  PCOS, Acne, facial hair, hair loss Fatigue, dry mouth, nausea, frequent urination Fantastic. About three years ago I gained about 60 lbs., got really greasy oily skin, and my normally thick, coarse hair had severely thinned out. My hair used to break combs in it's natural state and then suddenly I couldn't allow myself to be seen without a full head weave. I have always been hairy, but it had gotten completely out of control. I had hair growing everywhere except on my head. My scalp hair was thinning on the sides and top. I was beside myself. I felt monstrous. Then, drum roll please, I was diagnosed with PCOS. Ooooooooh. I was put on Metformin and that helped to an extent. I thought that Id never feel pretty again. I was then prescribed spiro last year. The side effects were kind of funky, but then again, the PCOS didn't make me feel so hot to begin with. I stuck it out and within months, my skin cleared up. I actually get compliments on my complexion again. I am no longer oily, more on the dry side now. Really small price to pay. The hair on my head is picking up, while the hair on my body is slowing down. I still have to tweeze and wax facial hair, but not nearly as often. One side effect that I didn't expect was that my already big boobs got even bigger. The fatigue isn't as bad. I use vitamins, get regular b12 shots, and use raspberry ketones to keep my energy up. F 39 1 years
100mg 2X day
4/10/2013
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 4  Facial Hair,Weight gain This drug within 4 months noticed a great difference in hair growth on my face. I am a 25 yr old woman and would have to shave twice a day just to not have a 5 o'clock shadow...now I can skip to every other day! yayy and it made my skin look pretty. F 25 6 months
1X day
2/15/2013
 4  Acne I been having VERY irregular periods... it really freaks me out to have twice a month or none at all. I have gotten off of this and my acne came back even worse so I got back on it again. My acne is almost all the way gone now just a little small one here and there. F 16 8 months
100 mg
12/31/2012
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 3  acne and oily skin Dry mouth,increased urination but less oily skin. Still no improvement in acne F 20 1 months
50mg
12/6/2012
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 2  Acne Bloating, weird changes in skin texture and elasticity--possibly scarring, mottled pigmentation, and accelerated aging. Loss of sex drive, fatigue, depression. Change in body shape and a seemingly permanent inability to gain it back. The medicine helped clear up my cystic acne in 3 months and, initially, I appeared to drop water weight, but over the course of a year, it gradually began to cause perpetual bloating, weight gain, and mottled saggy leathery skin! I'm so glad I realized it was Spiro b/c I honestly feel like if I had stayed on it for another year I would look 10 yrs older! Anyways, I actually expected to gain weight b/c this stuff increases your estrogen and lowers your testosterone (and therefore your metabolism and muscle mass--which is what helps you burn calories FYI) so I was VERY regimented and strict about my diet and exercise plan but apparently this stuff just changed my hormones so much that it didn't matter. I wasn't even on a high dose, but any time you increase estrogen you run the risk of turning all fat and soft. The fact that it lowers your testosterone makes it nearly impossible to keep the weight off--no matter how much you exercise or diet your hips will get bigger, mark my words! Wean yourself off slowly if you want to stop it, cuz this stuff really does a # on your hormones, and they wont be going back to normal any time soon (so you need to make it easier for your body). F 28 1 years
25MG 2X day
9/4/2012
 3  PCOS, hirsuitism Kidney stones, weight gain after going off. This drug did what it was supposed to do. It slowed my hair growth and made it lighter on my arms, legs, and prevented new whiskers from forming on my face. It caused me to lose 5 pounds of water weight while I was on it, which was nice... Until I got kidney stones, most likely from the chronic dehydration caused by this drug - it is a diuretic. I ended up in the emergency room in horrible pain and discontinued taking it at that time. I have since gained 10 pounds in 6 weeks. I'm assuming 5 pounds of water weight and 5 pounds of fat. The side effects were not worth the benefits for me, even though it did what it was supposed to do. I advise staying very hydrated if you are on this drug. F 25 6 months
150mg 2X day
5/24/2012
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 3  Acne Irregular/missed periods, urinating frequently, stomach cramps This hasn't really helped my acne yet but I haven't taken it that long yet F 19 2 months
50 2X day
4/20/2012
 4  Hair loss It caused some hair fall in beginning but thickened new hairs that replaced old thin ones and with rogaine it made a world of difference. Down side you can't stop treatment life long decision F 37 6 months
100
4/14/2012
 1  mild acne I am epileptic and on Lamotrigine as well. I have taken Accutane, which worked fantastically with no side effects, but had to stop early because I needed to go on medication for my epilepsy. There is apparently no interaction between Spironolactone and Lamotrigine. Since taking it I have had sudden fatigue (sleeping during the day - not normal for me at all); chronic anxiety; depression; dissociation; and seizures. None of these things were problems before (my seizures were controlled), and I found the mood disruptions extremely disturbing - especially as they were so noticeable and not at all within my normal range of experience. Very worrying. F 28 2 weeks
50 mg 2X day
3/15/2012
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