SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  bi-polar disorder Seroquel works at first, but over time it first loses effectiveness, then ends up working against you. I've been using seroquel for around a year now, but I take it only once every week or so to get my sleep pattern straightened around. The problem with this drug- in fact, the problem with ALL of drugs like this- is that it works for a while, but gradually stops working, and then one day it starts doing nasty things to you, like night terrors, paranoia, anxiety, hypochondria, and so on. None of these drugs are worth shit as per what they're supposed to be- not a single blasted one of them. These drug companies are full of crap on this point, and they have no business misleading people! The underlying problem is that something is wrong with a person's neurobiochemistry, which is a PHYSICAL PROBLEM. There is at present no way to fix that underlying problem. The problem with all of these drugs, seroquel included, is that you're introducing something artificial into a living organism. That living organism, us patients, responds until it can figure out a way around this instrusion. So the pr M 49 1 years
2/11/2006
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 1  bi-polar disorder Seroquel works at first, but over time it first loses effectiveness, then ends up working against you. The problem with all of these drugs, seroquel included, is that you're introducing something artificial into a living organism. That living organism, us patients, responds until it can figure out a way around this instrusion. So the problem is that all of these types of medications work at first, but have no long-term value as prescribed. As I get older, my anger and frustration with psychiatrists and drug manufacturers is growing. It's like taking your car to a mechanic, with steam and smoke billowing out from underneath the hood. But the mechanic, for some reason, is some jerk standing there with a blindfold and ear-plugs, and he staggers over, gropes your nuts, pulls on your thumb, grabs your ass, pokes you in the eye, and then says, "Okay, I've made my determination! Take this pill!" It's the language itself that's the problem. When I say "anxiety", for example, I'm not talking about any kind of anxiety that's within their experience. I'm not talking a &q M 49 1 years
2/11/2006
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 1  bi-polar disorder Seroquel works at first, but over time it first loses effectiveness, then ends up working against you. The problem with all of these drugs, seroquel included, is that you're introducing something artificial into a living organism. That living organism, us patients, responds until it can figure out a way around this instrusion. So the problem is that all of these types of medications work at first, but have no long-term value as prescribed. As I get older, my anger and frustration with psychiatrists and drug manufacturers is growing. It's like taking your car to a mechanic, with steam and smoke billowing out from underneath the hood. But the mechanic, for some reason, is some jerk standing there with a blindfold and ear-plugs, and he staggers over, gropes your nuts, pulls on your thumb, grabs your ass, pokes you in the eye, and then says, "Okay, I've made my determination! Take this pill!" It's the language itself that's the problem. When I say "anxiety", for example, I'm not talking about any kind of anxiety that's within their experience. I'm not talking a &q M 49 1 years
2/11/2006
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 1  postictal psychosis, psychosis NOS Paranoia, sever depression, slept all day and night, heart jumped out of my chest right after taking the drug. Inability to deal with everyday life events. Abnormal dreams. 400mg/115lbs. Diagnosed with posticatal psychosis , psychosis NOS , or bi-bolar at the age of 48. Attempted suicide after 3 months, advised doctors of depression induced by seroquel. They wanted to add another drug... said no.. Attempted suicide while on zyprexa 4 months earlier. Have any of you read MAD IN AMERICA BY ROBERT WHITAKER....... F 49 4 months
9/5/2005
 1  anxiety and anger management Makes me very very irritable. I'am worse off than before I started taking this medication. I have ony taken it for 13 days ..but I have to stop. It is affecting my job and home life ..because I'm so damn cranky on it. I called my doctor about this.. he said to continue taking it..it may kick in about 3 weeks..the thing is I can't wait that long because I won't have a job or a family by then. I just stopped.. I only take 100mg at bedtime..it does help for sleep..but I never had a problem sleeping. It didn't work for me and I don't plan to take it anymore. I was wondering if other people had these type of effects from taking seroquel. I'm talking about the overwhelming irritability. M 49 13 days
1/23/2006
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 1  Insomnia, PTSD, DID Horrific nightmares, extreme panic, flashbacks increased in severity and length, wake up drenched in sweat, body would suddenly jerk, zombie feeling, no sex drive, intense weight gain then lost appetite completely, severe depression, tingling and numbness These drug terrifies me now. I stopped taking it a week ago and my mind is clearer already. My doctor said it would help me sleep and instead I ended up in a world where I didn't know what was real or not. Then started drinking heavily to deal with the nightmares and anxiety, would rather pass out then be in any state to dream. Now I am not taking anything except Lexapro, no over the counter, no alcohol. I was in hell when I was on that drug and wanted to die. Learning how to sleep in a more natural way. Lacked desire to do anything. Would have these hideous experiences while only taking 50mg. I am so glad I found this website because it let me know that I am not alone in my reactions, I am not losing my mind. After reading this website, I took one 50gm dose and nothing else and that night, horrific panic attack, hallucinations both visual and aural, intense fear when I finally feel asleep a nightmare in which I thought I wold scream forever and woke drenched in sweat. F 49 9 months
8/18/2009
 5  Bipolar One hour after taking, it puts you into a heavy drowsiness, almost into a stupor. You simply have to go to bed; I can't imagine anyone doing anything waking/active at all once the drug kicks in. Causes the profoundest sleep you've ever had; a godsend to those of us with hyperactive minds. Often it seems to make the night fly by instantly: One minute you're lying down, the next minute you're waking up 6-8 hours later, with no memory of having slept. Surprisingly, you awaken with little or no grogginess; the fog lifts within 30-40 minutes. I do find I need 2 cups of coffee, though to get me into the swing of active thinking. Seroquel's most disagreeable side-effect for me was, as the drug takes effect, it causes your nasal passages to swell up and shut tighter than a drum; on one occasion, very alarmingly, I felt I could barely breathe through my mouth, either. Nose spray (oxymetazoline) totally relieve this, however. Seroquel really feels like a p It's a life-saver for those with manic, hyperactive, "monkey-minded" minds, and those of us recovering from substance abuse; It reins in paranoia. I take it as a strong, effective sleep-agent, but I know a schizophrenic who takes 800MG per day! Good lord. M 50 10 years
100MG 1X day
1/6/2014
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 5  Insomnia None at all. This is a miracle drug! I had been taking Ambien (the Devil's drug) but switched to Seroquel and take 200mg at night. There are no side effects and I have finally been sleeping like a baby for over two years :) M 50 2 years
1/14/2010
 5  Insomnia & anxiety with depression A little tired in the morning, but that went away after the first week or so. I've been clinically depressed for years. I'm taking 50 mg of Prozac, and developed insomnia after several years---no trouble falling asleep, then wake up at 2 am and never get back to sleep. Was exhausted all the time. New doctor added 25 mg of Seroquel at bedtime, and it has worked beautifully--I get a full night's sleep. Sometimes I'm a little groggy in the am, but once I'm up and about it's gone. My mind is clearer, my bad moods are gone. I think it's a great supplement to Prozac for depression and insomnia. F 50 43 days
3/12/2006
 5  Sleep / Bipolar Depression If I don't sleep at least 8 hours, I'm a little groggy in the morning. On those occasions, a 12 oz. can of Mountain Dew (which contains about 1/3 the caffeine of a regular cup of brewed coffee) generally does the trick. Otherwise, I have not noticed any other side effects and have not experienced any weight gain at doses of 12.5 to 50 mg. When reading someone else's experience with ANY drug, ALWAYS remember that your experience may be different. Try something until it's clear that it's not right for you. The drug you refuse might be the one that'll save your life! I have been taking 12.5 mg of Seroquel predominantly for sleep. I absolutely LOVE how it puts me out/down in about an hour and helps me sleep through the night. At higher doses (25 or 50 mg), I am too groggy the next day. When I'm hypomanic, its ability to keep me down through the night is reduced. On those rare occasions, I increase my dose to 25 mg and that helps. M 50 9 months
12.5 mg 1X day
9/26/2010
Patient History
 5  Hormonally driven mood swings Only dry mouth and perhaps a little grogginess in the morning. That goes away very quickly. I am 50, in very good health, very fit and starting to go through my changes. For the past year I have felt out of control. Every month, regardless of whether I get my period I feel out of control, depressed, anxious and unable to get a grip on things. I have tried a number of meds that have made me feel toxic as I am sensitive to medication. I take the lowest dosage of Seroquel and cannot believe the difference. Within 2-3 days I felt like myself again - clear, even, strong and with the ability to sort everything out just fine. I felt jumbled and had a constant knot in my stomach before Seroquel. I hate the fact that I need meds for anything but this has been a Godsend!!! F 50 45 days
1/2/2009
 5  anxiety It makes me very sleepy - but I take it at night and for the first time in my life, I sleep thru the night or awaken and can get back to sleep, so the 'side effect' is totally desired. (I take 50 mg.) It greatly eases my anxiety and this former insomniac can no longer do without it to get thru the night. F 50 2 years
10/5/2004
Email
 5  Bipolar 1 w/ pychosis A slight hangover in the morning and some weight gain. it helps in alot of ways. with my depression and with my hatefull actions. makes me mellow! M 50 4 months
8/1/2005
 4  Bipolar Disorder Chronic ringing in my ears. Short term memory loss. Periodic muscle twiching in my arms and legs, following nite time dosing. Taking 400mg at 7:00 PM daily. Seroquel is very effective as a antidepressant. Very good sleep inducer. Without the drug, I am unable sleep more than 3-4 hrs. per nite. In combination with Trileptal, moods are balanced. Compared to other drugs used for similar treatments, there are very few side effects. M 50 2.5 years
12/15/2004
 4  Sleep Apnea compliance to CPAP I was first taking Seroquel XR at 150mg and I felt like I could not get enough sleep and stayed kind of blah all day. My doctor switched me to quick release Seroquel and I am much happier with that. The idea behind prescribing this to me was to help me sleep better so that I do not take my CPAP mask off. To date, it has done the trick. I wake up feeling rested, clear minded, etc. I wish I had started taking it long ago and then maybe I would have been more compliant with my CPAP mask. I would be happy to share my experiences with this medication if you wish to email me. Good luck to all of you. M 50 21 days
200mg 1X day
10/7/2010
 4  mainly for sleep, and mood stabling Nocks me out pretty quickly, as long as I have not eaten recently. I wouldn't think of taking it before I have to do anything important.. Also, I wake up every night with the need to eat and can't fall back to sleep without eating a bunch first. Gained some weight, but not a lot and I really haven't been getting much exercise so I can't complain. I also am somewhat groggy in the morning, but I take 36mg concerta and with that and a cup of coffee, I can focus and do things. Before Seroquel, I could not sleep most of the night. Now I take 100mg along with 10mg valium and 200mg Lamictal at night and it makes me fall a sleep. Only problem is that I wake up every night and have to eat (like the munchies). Can't fall back a aleep without eating, a lot. Sometimes if I have food near, I find myself waking up already eating. Kind of strange. But I have to admit that I get much more sleep than I did before taking Seroquel. Also, in the past, I did not remember any of my dreams when I woke up, for a long time and now I often remember them and they have actually been somewhat pleasant, not like I remember in the past. M 50 10 months
2/20/2007
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 4  I am Bipolar who does not sleep I was perfectly happy with taking seroquel until my eye dr. told me that I now have cararacts I like so many others I do not sleep. I can't go to sleep. I lay there for hours on end. I have been known to stay awake and alert for 2 weeks at a time. My Psyc. put me on seroquel. we played with dosage, tweaked and added trazodone. I sleep better but still have nights where I only reach lala land. Yet I feel rested when I get up. Now I find out that I have caratacts caused by seroquel. I will have surgery to replace the lenses in my eyes. But what other drugs are out there to cause me to go to sleep? I've used lunesta and ambien with no effect. Has anyone tried some thing that even got close? F 50 4.5 years
1/14/2010
 4  Chronic Insomnia Dry eyes, dry lips. Take with fish oil to offset the dryness F 50 1 years
25mg
8/18/2022
 3  Bipolar 2 manic depression suicidal Insomnia, racing thoughts, blackout anger moods, Seroquel Madness, If I fall asleep in an angry mood, I will not deep sleep but will be in a blacked out state get to what the reason i am mad and commence to do what I went there for. I think it is one of the worst things that could be prescribed to me M 50 9 years
1200mg 2X day
12/18/2014
Email
 3  bipolar disorder nightmares, hangover in the morning which eases in 5 minutes with a cup of coffee. cognitive obtunding, i have no interest in the acedemic writing and reading i'd usually be enthusiastic about, no libido, completely uninterested in romance. i did have slight restless leg, weird uncomfortable feeling in hip joint but splitting the dose -300mg taken as 150mg .b.d. stopped that. i was regularly getting incarcerated in a horrible public psych ward with cruel staff against my will and was under threat of eviction due to manic behaviour, seroquel totally controls my symptoms which gives me security, i don't have to live in fear of the psych staff ringing the doorbell. previous regimens included several drugs, valproate + lamotrogine +rispiridone, horrible discomfort and side effects, life wasn't worth living. seroquel works for me on its own, i'm not on any other drug and since it doesn't physically hurt me like rispiridone did i'm willing to pay the price of the side effects i have in order to keep psych detention and eviction at bay. F 50 2 years
11/30/2009

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