SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Bipolar disorder Increased appetite but not a problem when taken last thing at night. A little groggy in the morning but easily solved with a coffee and nowhere near as bad as insomnia-induced grogginess Absolute life changer, 200mg nightly allows me to sleep after decades of insomnia. 25 or 50mg taken as needed to mitigate depression, rage and/or mania on the fly works well. Clearly a lot of people have had problems with seroquel (quetiapine) but I can't recommend it highly enough. If your bipolar controls your life, as it did mine, quetiapine can give you your agency back. Speaking of which, you'll only gain weight if you allow it. M 47 10 years
200 1X day
9/3/2022
 5  Major depressive disorder, generali After the first few days out of the psyche ward I was prescribed this: 300 mg twice a day. I did not know how I would ever take this drug during the day as it made me extremely tired. It was wonderful at night for the insomnia, but the grogginess at the time my alarm went off in the morning was immense. I felt like crying for no reason. I had suicidal thoughts, an empty lethargic feeling and an appetite like a bear. I persevered, and allowed my body to build up a resistance. Eventually the extreme tiredness during the day eased off and the negative effects dissipated.. I sometimes get this tight feeling or a pain in my chest, above my heart. Sometimes it feels like there is a piece if ice stuck in my heart as crazy as it sounds. My herat beats fast sometimes. I have gained 15Kg’s but this may also be from the Remron, I am not sure. I feel very lazy at times, battling to do basic home chores. This drug has the potential to diminish ambition, or creative expression Second to Zyprexa, this is a miracle drug for me. I am more stable in my moods, my anxiety is lowered and my depression is relieved. I highly recommend that anyone taking Seroquel persevere for the first two weeks until the really horrible tiredness goes way. Then see if it works for you. M 47 6 months
300 2X day
9/4/2013
Email
 5  Insomnia and anxiety Deep sleep 7-8 hours per night. Less anxiety. No negative side effects at all. F 47 3 months
12,5mg
6/3/2016
 5  bipolar I Sugar cravings, require 10 hrs sleep, mild restless leg syndrome, slight weight gain, involuntary finger/toe movements. Grogginess for about 30 minutes in the morning which goes away. As bad as the side effects sound, bipolar I is scary and debilitating, and this drug has turned my life around. I take a fairly low dose, 100 mg, unless becoming manic, when I increase it to 200 for a few days. With consistent exercise and careful eating I can keep my weight under control, and blood sugar is good. I refrain from eating at night after I take the drug - just go straight to bed. Also I take lamictal and lexapro. Have been stable five years. Seroquel helps with anxiety, too. I feel very good. F 47 5 years
11/23/2009
 5  sleep You must be able to have the time for at least 7 hours of good solid sleep. 25 mg. is best for me at 5'6 F 47 2 months
8/9/2005
 5  Bipolar Depression/Sleep It causes my nose and sinuses to close up tighter than a drum, sometimes creating an alarming sensation of choking or suffocating. I think it also causes swelling of the prostate, making it difficult to pee when you want to. I generally have been pleased with SEROQUEL. Starting in my middle-age, I have been plagued with insomnia... racing thoughts very much a part of that. I had tried "baby" sleep aids like RESTORIL and AMBIEN, but they were just pi$$-in-the-ocean: Basically I am like an elephant in the wild who needs to be brought down with a dart of elephant tranquilizer! So I needed a more "heavy duty" sleep aid like SEROQUEL. A relative of mine takes about 700mg daily for schizo-affective disorder... There is no way in hell I could take a dosage like that, because 100mg alone is enough to knock me out cold for hours, swell up my nasal passages completely and dry up my mouth. SEROQUEL does indeed allow me to sleep like a baby for about 8--12 hours, and get plenty of refreshing REM sleep, too. In fact, it is the first good sleep I have had in all my adult years. I am just naturally "wired" by nature, and SEROQUEL eases that. Interestingly, once you awaken, you are not groggy at all... 10 minutes, say, for the fog to lift... and you're good. I have in fact, gained much weight since I've been on psych meds (ten years now) and have developed Type 2 Diabetes as well... but I attribute these developments more to DEPAKOTE... which I'll "diss" on a different page... As a diabetic, I probably should not be taking a drug which metabolizes in the liver (as SEROQUEL does)... It would be prefe M 47 5 years
100mg 1X day
6/29/2010
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 5  Bi Polar Depression Only that it makes me tired I was on put on seroquel because I was so depressed that I could not sleep at all..I started out at 25mg nightly and slowly increased to 100mg nightly..after about a year I went off of it because my symptoms were not as severe..Then a year and a half ago I fell into a really really dark place...I cried for 2 months, hardly ever stoping..and not sleeping at all...maybe an hour at a time..At that time I was diagnosed with bi-polar depression and started on 400mg nightly and honestly it saved my life..I of course got a good nights sleep the first night I took it and very quickly I started to feel more like myself..I stopped crying and started to have a somewhat normal life..My sister-in-law who suffers from depression also said to me "welcome back to the land of the living" the changes were apparent to everyone around me.. I don't think this medication is for everyone, I think it should be evaluated by anyone taking it weighing the good with the bad..Just because it works for some does not mean it will not be the worst medication others have ever taken.. F 47 3 years
400mg 1X day
3/26/2010
Email
 5  Insomnia No side effects. The doctor prescribed this medication for me to help me sleep after other methods and drugs failed. I don't have a problem falling asleep but I have a problem staying asleep because I have a very active mind. I started out with 25 MG taken at bedtime but the doctor had to increase the dose every few weeks as my body got used to the medication. My maintenance dose finally came out to 300 MG and I have been taking this for 7 years now. I do feel groggy in the morning especially when I don't get my 8 hours of sleep but it's a small price to pay for restful sleep. I did find that taking the medication on a full stomach lessens the sedating effect of the drug. I am a bit worried about getting tardive dyskinesia in the future though the chances are slim as this is an atypical antipsychotic. Nevertheless, the risk is worth it. M 47 7 years
300 MG 1X day
8/18/2012
 5  BPD/Bipolar/Insomnia Weight gain, restless legs, apathy, terrible constipation, memory problems, lack of motivation for communication with people, it has affected my eyesight. Along with psychotherapy. this drug worked like magic. The weight gain however is frustrating. Was on 800mg down to 50mg. Am weaning myself off this drug as I am taking Zeldox, another antipsychotic. I want to lose weight. I will get another drug to sleep. I've had terrible times when trying to go cold turkey off this drug. F 47 6 years
100mg 1X day
1/21/2013
 5  bipolar disorder makes me very sleepy, so only taken at night. When taken on empty stomach, I may experience blackout, no memory of how I got to bed the next morning. I am told I do not act abnormal, I just can't remember anything. Have not had much problem with weight gain. Has helped with moods and biploar disorder. F 47 2 days
10/27/2004
Email
 5  schizo-affective disorder dry mouth. morning sleepiness. I love this drug. I take 75mg of seroquel with risperdal, gabapentin and effexor. It has given me sleep and serenity. It has been years since I was able to go to bed and feel assured that I would fall asleep and stay asleep. I am calm during the day and social skills have improved. Less anxiety around people. Fewer hallucinations. F 47 90 days
6/23/2005
 5  Severe insomnia A little foggy headed when I first get up in the morning I tried everything to help me sleep: Ambien CR, Tylenol PM, Lunesta, Rozerum, nothing helped. Sure, I could go to sleep but within a few hours, I'd be wide awake with my mind racing. This made functioning during the day impossible. I take 12.5 mg Seroquel within an hour of going to bed and it helps me sleep for 7-8 hours. I'd be lost without it. I can't imagine taking a strong dose though - F 47 1 years
12/30/2007
 4  Anxiety, Depression Initially, very sleepy. As I continued taking it weight gain (25-30 lbs on my 6' frame). It's worked great for me except the weight gain. I take 100 mg right before bed, read for 15-20 minutes and then I'm out like a light. Vivid dreams, but no bad ones. Wake up feeling great. M 47 3.5 years
11/20/2008
 4   somnolence. hard to move around. unmotivated. M 47 3 months
4/11/2006
 4  sleep aid It just worked perfectly for the problem of getting to sleep. I haven't noticed any side effects except one BIG one, weight gain. I suspected it but did not really confirm in my mind that Seroquel was related to my weight gain until I just read some postings and some of them fit me to the T. I have gained at least 25 lbs in the little over 1 year I have been taking it. Two months ago I started on a big diet and exercise routine. I mean BIG exercise. I hadn't exercised in 2 years and it was a big deal. Well, I only lost 11 lbs and I was STARVING myself and working out 4 times per week. It was just killing me! You know, you get a little frustrated when you're killing yourself on a grueling routine and get NOWHERE. So, Seroquel works GREAT for knocking me out BUT gaining all of this weight practically makes me want to sleep! (Run and hide.) I've decided to go off Seroquel (100mg)a night and try to just take Lunesta and Benadryl to sleep. I really hope it works because I just M 47 1 years
9/13/2005
 4  BP,Rage,Depression,Bizarre thoughts A bit sleepy during the first month. Now taking 50mg morning, 50mg night. Started with 25, and went up from there until I felt good. Also take 300mg 5-HTP, 900mg St.John's Wort, 20mg Lithium Orotate. Seems to be a great, side-effect free cocktail. Great sleep, great dreams, much calmer and happier. Still enjoy life, but not worried about freaking out. Have been taking all the other things for about 2 years, but still needed something to "take the edge off" and Seroquel seems to be the answer. F 47 2 months
4/22/2009
 3   Groggy, grumpy, cranky. I took it for anxiety and sleep problems. It help's a tiny bit, but then after a couple days I was too cranky and moody to continue medication. Felt like I drank cheap wine the next day, kinda like Trazadone. M 47 14 days
50 MG 2X day
2/2/2015
 3  insomnia, mood swings Was on this drug for almost a year. Had to discontinue due to restless leg (so bad it kept me awake for hours... insomnia was the main reason I was on the drug.) Also toward the end of a year memory loss (was at a store counter filling out a form and could not remember my address!)and weight gain. Restless leg aside, it was great at first. Slept solid, no waking up, did not gain weight, increased libido. It turned on me after about 11 months. Had to discontinue. M 47 1 years
50 mg 1X day
3/17/2012
 3  bi polar 2 calmed me but tired all the time F 47 3 weeks
300mg 2X day
2/12/2010
 3  dissociation, borderline personalit Stuffy nose, restless legs, weight gain and if I forgot my night-time dose I didn't sleep all night. I was on 200mgs. at bedtime and am now on 50mgs. I have been having a difficult time coming off. The doctor has to keep increasing and then decreasing the dosage. I get extreme irritability which comes and goes. F 47 2 years
10/11/2004

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