SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  major depression,psychosis dry mouth,some memory loss,dizzy,unusal moods,emotional numbess,exhaustion,ringing in ears have been on 400mgs a day for a month.dont know yet if the benifits(less anxious,less easily upset,moodswings lessen)is worth the side effects. M 48 4 weeks
11/28/2003
 2  chronic schizophrenia extreme anxiety about 30 min after taking it; difficulty breathing that led to ER visit; insomnia; nightmares I had taken it once before w/o problems but this time I couldn't tolerate it F 48 3 months
4/25/2007
 2  Misdiagnosed Bipolar, sleeplessness Dry mouth, problems with balance(unsteadiness), disorder of words when speaking, slow to follow conversations, disruptive thoughts, continues desire to sleep more, weight gain +++,nightmares,diarrhoea One tablet put me out of action for a night and half a day. If not taken sleeplessness intensified - most probably to dependancy. I had terrible nightmares. Short term memory was effected. I forgot what I wanted to say or what I wanted to do. I suffered from severe diarrhoea, upper abdominal pain & general disorientation. I experienced the feeling of being out of control on several levels of my life. It was not the right medicine for me! F 48 8 months
4/28/2007
 2  anxxiety It worked great at first for helping me sleep and evening out my mood. However, it worked a little too well. It doesn't just dull the anxiety or bad mood, it takes away the happiness to. I wasn't unhappy, just more flat. Took away sex drive and am working with doctor to get off of it. Unless you are schizophrenic not worth the risk. Had insomnia when I had to discontinue for a period. Felt weird joint pain, slightly sweaty palms and forgot tons of stuff. Felt stupid as I tried to think of a word. Don't take this drug. So many other options, not worth the risks and very hard to discontinue without tapering under medical supervision. F 48 3.5 years
12.5 1X day
6/11/2013
 2  insomna sex drive gone../ weight gain unreal F 48
75 1X day
3/7/2012
 1  Bipolar nos Side effects were weight gain rapid heart beat ,pressure pain on my chest , tired from the time I woke up; bloating and swelling of the stomach and problems with my Bowles.also developed a peptic ulcer and type 2 diabetes. just came off seroquel last week doing much better, this medication is horrible ruined my life for 2 yrs doctor would not change my medication so I changed doctors to someone who saw what the side effects were doing to me and now I am able to live my life again. M 48 2 years
300mg
12/15/2012
 1  PTSD/Anxiety Gained 60 pounds, continue to have issues with PTSD, vivid dreams, flashbacks, anxiety, short attention span. General decline in an already poor health. I am trying to ween myself off of it as I lost my job/insurance and it is to expensive to buy. The side effects are increased anxiety, insomnia, feelings of impending doom. F 48
100 2X day
9/8/2010
 1  manic-depressive disorder Worst effect was when I would try to get up at night and would colapse onto the floor as none of my muscles would work. I would try to talk and just slurring would come out. My mind was coherent but my body would not work. VERY SCARRY!!!! My husband said "THROW THEM OUT" and I am absolutely taking his advice. I described this to my doctor and she didn't seem so concerned. I think when our doc's prescribe things like this they don't take the time out to research the drug themselves, so they can't warn us of these horrible side effects. For some, they do more harm then good. F 48 4 months
12/4/2005
 1  major depression tired,confused,emotional numbness, dizzy, ringing in ears,hangover feeling in morning, dry mouth,weight gain,etc. etc. garbage. I am tapering myself off. M 48 3 months
1/12/2004
 1  bi-polar 2 Extremely unpleasant background anxiety. Unable to sleep. Slept a lot at first. Began to feel great. Drug lost its efficacy over the weeks. Now gives me anxiety, won't let me sleep. Racing heartbeat. Without the anxiety, I'd be feeling just fine, so this drug is a great disappointment. By the way, this is my experience, not my opinion. My opinion is that drug companies should stop wasting time experimenting on lab rats. A lab rat can't tell you how it feels, so you don't know whether the drug you're trying to develop is on the right track or not. When dealing with a non-verbal situation, you're attempting to extrapolate data from appearances only. I think we all remember the joke about the researcher who pulled off the grasshopper's/cricket's legs one by one. M 48 2 months
9/3/2004
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 1  depression A.R.D.S. doctor told my husband I had a 60% chance of living seroquel caused a lung infection then blood clots form.....next went into surgery , heart stopped 3 times they broke a rib doing cpr.,,,,,,,then i had a stroke AGH! F 48 60 days
6/21/2007
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 1  What my doctor calls "hypomania." I HATE the way this stuff makes me feel. It's terrible. It makes me feel groggy and drowsy, but it doesn't help me sleep. It makes my restless leg syndrome worse, just like antihistamines do. I also feel sick, kind of like a bad hangover. There's also kind of a jitteriness in the way I feel. It's like my muscles have been sedated but my nervous system hasn't. There's just as much anxiety as before taking the drug, but you feel so groggy and letharic that you can't do anything to ease the jitters. This is a terrible drug. My doctor prescribed it for a condition she calls hypomania, but after taking just half of a 50 mg pill I can tell that this is not what I need. The grogginess and lethargy might be okay if the drug actually helped me sleep, but it doesn't. It's like it both sedates and excites my nervous system at the same time, so my body and my mind are confused as hell. I couldn't wait for the effects of that 1/2 pill to wear off. My doctor said that she has had patients who take a 600 mg dose of this drug. I think 600 mg would kill me, seriously. The effect from just 25 mgs was almost too much for me to bear. If you decide to try this drug, be very careful. Better yet, don't take it. M 48 1 days
25 mg
6/24/2016
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 1  Insomnia, Schizotypal Personality D Increased appetite. Massive weight gain of 100+ pounds. Development of type 2 diabetes. Development of sleep apnea. Fatigue, lethargy & apathy. I have been on this medication for around 15 years now. I have tried going off it many, many times. I even slowly tapered it down to 6.5 mg, but always ended up back on it because without it - I wouldn't sleep at all for days, until I would usually start hallucinating and feeling like I was coming apart at the seams. Nothing else seems to work for my insomnia. I am fed up with constantly feeling tired all day and am sick of being so overweight. I went cold turkey 7 nights ago & have only managed 8 hours of sleep TOTAL since. I'm exhausted, but OK mentally, in part thanks to being on Prozac & in part to being so determined to get off of it for once and for all. While it guaranteed sleep for me, it simply wasn't worth the side effects. F 48 15 years
6.25-500mg 1X day
4/12/2016
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 1  insomnia do not take this drug for any reason. It is pure pure evil. It was prescribed for insomnia, which works very well, but the side effects are horrendous. gained 60 pounds. walked around stoned everyday. do not listen to the doctors when they say this drug is not addictive. I have been on this drug for 4 years and the withdrawal is absolutely unbearable. it has taken me more than 5 or 6 months to get back to normal. please please please stay away from this drug. doctors will tell you this is a harmless drug. Do not listen to them. you are in for a lot of trouble if you start this drug. at first you will be happy you're able to sleep, but believe me it is not worth the horrible horrible insidious side effects. M 48 3 years
200 mg
3/13/2015
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 1  Sleep Very tired within 20 minutes, but no deep. Weird vivid dreams when I would start to drift off waking me back up, only I couldn't open my eyes and it was hard. Hard time reaching to turn off alarm, took several attempts to push the button. Severe muscle fatigue in hands and arms with trembling. Hard time dressing, poor motor skills, inability to find words, almost felt I was in slow motion, brain fog, eyes swollen underneath like never before, sensitive to light, unable to drive, weird overall feeling of distance or separation from everything around me, very difficult to function. All this after just 1 dose! I will never take this medication again. When it was first prescribed to me 2 months ago, I read reviews and side effects and refused to take it. My Dr. talked me into it saying she thought it would help me sleep better. I would rather never sleep again than ever feel like this. F 48 1 days
50 mg 1X day
1/19/2021
 1  Sleep Very tired within 20 minutes, but no deep sleep. Weird vivid dreams when I would start to drift off waking me back up, only I couldn't open my eyes and it was hard to move. Hard time reaching to turn off alarm, took several attempts to push the button. Severe muscle fatigue in hands and arms with trembling. Hard time dressing, poor motor skills, inability to find words, almost felt I was in slow motion, brain fog, eyes swollen underneath like never before, sensitive to light, unable to drive, weird overall feeling of distance or separation from everything around me, very difficult to function. All this after just 1 dose! I will never take this medication again. When it was first prescribed to me 2 months ago, I read reviews and side effects and refused to take it. My Dr. talked me into it saying she thought it would help me sleep better. I would rather never sleep again than ever feel like this. F 48 1 days
50 mg 1X day
1/19/2021
 1  Sleep and racing thoughts Just an awful drug for me. Instant zombie on lowest of dosing and no cease of racing thoughts. Did help with sleep the first few nights. Extremely powerful and caused/lead to some black holes memory wise for me. This one wasn’t for me. I was groggy even minutes after taking it. Memory gaps and lethargic state were terrifying. 48 7 days
12/10/2019
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 1  No idea, Dr didn't know either Difficulty swallowing! I don't trust the medical or pharmaceutical world, especially after being prescribed this "drug" when the doctor knew nothing, and I do mean nothing, about me. No longer taking M 48 4 months
100
11/26/2019
 5  PTSD, lack of sleep Vivid dreams, groggy wake-up (use caffeine to overcome) no weight gain until I stopped smoking, slightly high blood sugar. Starting taking seroquel while on active duty and deployed in Iraq due to sleep problems and PTSD in 2009 at 25 mg, now retired from active duty and I take 200 mg before bedtime, If I don't take it, I will not go to sleep. Weight gain only after I stopped smoking in 2016, considering the small bad effects I rather take it than not. Recommend small dosage at first, plus be positive about life, it could be worse as I seen and experienced worse in Iraq. M 49 11 years
200 1X day
2/16/2020
 5  Bipolar I Significant drowsiness* and weight gain, disorientation* starts after 10 minutes, blunted affect*, feelings of mild dissociation, and occasionally euphoria. Antipsychotics are notorious for for lowering or downright eliminating libido and causing other sexual dysfunctions. *reason 400mg is taken all at once just before bed I submitted a review at the end of December 2013 and thought it would be helpful to be followup. Seroquel is an effective anti-manic med. but it’s also FDA approved for bipolar depression. I occasionally experience psychoses when severely stressed and sleep-deprived and Seroquel helps with those symptoms also. These brief psychotic responses are extremely upsetting so my doctor also prescribed PRN 25mg pills (up to 100 mg) to be taken when my thoughts become jumbled, racing or irrational (delusional) including suicide ideation. The 25 mg pills are the lowest dosage available and tiny enough for sublingual dosing when I deteriorate rapidly. Taking 25 mg starts to slow my thoughts and “dial-down” intense emotions which produces a deep calming affect. (I would not consider such a change to be “emotional blunting” (negative) under the circumstances. I will take a second, third and final dose until noticeable improvement. Seroquel is deeply sedating so driving can become dangerous. Seroquel is a powerful drug with considerable side effects and patients sometimes develop other health problems because of taking this drug. My goal (with my doctor’s consent) is to decrease my dosage to the lowest amount possible. Seroquel has been very effective in alleviating symptoms but I’ve never felt truly comfortable taking it. F 49 6 years
350-400
4/9/2019
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