SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Borderline, Sel Harm, Depression Hard to wake up, hard to lose weight- in fact a slow steady gain, 'jumpy' legs occasionally or similar tics. Increased appetite. Its v good.! Have been on all the others-and the weight thing is certainly not as bad as on Largactil or Zyprexa. Also, stops the mild paranoia and if i feel agitated or even like S.I, i just take 200mg and it stops me doing anything stupid. For anyone with S.I. issues, this is a great med. F 35 2 years
2/9/2007
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 5  Bipolar--mixed episode Weight gain (in just 7 days!), muscle soreness (has anyone else experienced this?), lethargy, increased appetite (I want to eat everything in sight!), I am doing well except for the weight gain--I lost 60lbs in the past couple of years from drug side effects and I don't want to gain it all back again. I don't want the depression of weight gain in my life. Any ideas? I am thinking of getting back onto Weight Watchers, but with the mixed episode and the lingering depression at this time, I just don't think I have the energy left. I also don't have clothes to wear if I gain weight--I got rid of all my bigger clothes. Help! Any ideas? suicidal thoughts are gone, sex drive is still good, i love that I can sleep again (I do wake in the middle of the night, but I can fall back asleep with few problems), I don't hate everyone anymore (decrease anxiety and irritability), increased concentration and cognitive functioning (I actually can make a joke again and I know that means that I am doing better because my brain in processing information at a good speed--not too quick), I don't dread the words that come out of my mouth such as "shut up you stupid idiot!" (while people may need to hear this, I now am beginning to feel that I have a "ego filter" for my id again!). I am currently taking Lamictal 300mg, Seroquel 100mg, Klonopin 3mg. I was on Klonopin and Lamictal only for 2 and 1/2 years and was doing great and then in the past month I became manic/depressed again and on the verge of psychosis--I started getting paranoid which has never happened before. Please keep talking because I feel alone in this a F 35 7 days
12/24/2006
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 5  insomnia/mixed state bi-polar It's made it difficult to lose weight, but I don't think it's made me gain any. Memory is definitely affected. Seroquel saved my life - I didn't sleep for 6 years and was on a slippery slope down the bipolar path. On Seroquel, I sleep like a normal person and no longer have the intense anxiety, anger, or depression that characterized my daily life. Also- if I allow less than 8 hours of sleep on Seroquel, I feel drugged out - but that has forced me to take care of myself and actually schedule enough sleep time. F 35 2 years
11/25/2005
 5  insomnia/mixed state bi-polar It's made it difficult to lose weight, but I don't think it's made me gain any. Memory is definitely affected. Seroquel saved my life - I didn't sleep for 6 years and was on a slippery slope down the bipolar path. On Seroquel, I sleep like a normal person and no longer have the intense anxiety, anger, or depression that characterized my daily life. Also- if I allow less than 8 hours of sleep on Seroquel, I feel drugged out - but that has forced me to take care of myself and actually schedule enough sleep time. F 35 2 days
11/25/2005
 5  Nightmares, disturbed sleep, PTSD Slight groggyness on waking & sometimes daytime lethargy if taken too late; and fewer than 8-9 hours sleep has been had. Elevated cholesterol levels. I take Propranolol for anxiety (PTSD) during the day & 100mg Seroquel at bedtime to maintain sleep and stop nightmares. I love this med. It feels like more natural sleep patterns. Feeling tired and dropping off within 30 minutes to an hour of taking it. Staying asleep all night & even having normal REM dream sleep - pleasant dreams & no more nightmares. :) F 35 2 weeks
10/18/2006
 5  Bi-Polar II; obsessive thoughts Slight weight gain. Occasional drowsiness in afternoon. Nothing too serious. After everything else failed, only Seroquel solved my problem. Zyprexa and Risperdal wore off after several weeks. I'm on 600mg temporarily, will soon go down to 300 or so. Without Seroquel, I'd be far worse off. M 35 15 months
12/29/2007
 5  Schizo Affect Sometimes when the medicine is kicking in and I try to stay awake (at the computer TV etc...) I experience hallucinations and lathargy. I feel punch drunk etc... I take 1000mg (Heavy Duty Dose) at bedtime or thereabouts. I do this to avoid the sleepiness and knee tremors if taken during my daytime hours. For the most part I wake up sleepy sometimes I feel blunted in my awareness and emotions. Other than that this med has been much better than Zyprexa, Risperdol and definatley better than Navaine (Spelling?). I have also experienced weight gain on Seroquel. I have at times due to the responsibilities of my life had to take lesser doses to be able to wake up earlier. I do not advocate this as my blood level has slipped too low on different ocassions and I started to experience full blown symptoms of Schizo. I take Nuerontin and Attivan as well. My doc is trying to ween me off those currently. M 35 6 years
7/20/2005
 5  Bipolar I Current dose is 400 mg/day. The expected drowsiness and weight gain (in my case 15 pounds, which on a formerly 130-lb, 5'4" frame is a lot of weight). Weight is coming off gradually though. Mild increase in heart rate & drop in blood pressure within first hour after dosing. My psychiatrist reviewed any and all potential side effects with me though so I was prepared, which makes things much more manageable. Also, I spread my dose out into 4 100-mg doses throughout the day, so I don't experience extreme fatigue, dizziness or passing out which was a problem for me when taking 200 mg or more at a time. Overall, great stuff. For me, works better than anything else I've tried (which includes Risperdal, Zyprexa - which brought on extreme heart palpitations - and Lexapro). One thing to remember is that everyone reacts differently to each drug. The only way to truly know if something will work for you is to try it, under the supervision of a good psychiatrist. F 35 6 months
6/3/2007
 4  bi-polar I I have experienced no adverse side effects. Seroquel saved my marraige, job and life. I have been in my manic state for several months, I feel my cycle of depression beginning but have yet to suffer. I am hopeful seroquel will not only help greatly with being manic but also ward off depression. I feel more focused and alive than I have in years. F 35 5 days
7/25/2005
 4   I gained 25 lbs pounds and worked out daily and eat nutritionally each day. FYI this medicine causes at least 10 lbs gain from medicine alone Be careful of weight gain and this slows down your metabolism and also makes you hungry more (scary about weight gain)!!!! F 35 9 months
12/16/2006
 4  sleep deprived Weight gain of 30lbs at range from 200-400mg. The drug worked for me, but I also had weight gain. 30 lbs. I tapered down on my own to 25mg. I've lost 35lbs and have the energy to exercise again! I'm trying to get pregnant and my doctor would like to eliminate as many drugs as possible. I also take 400mg Lamictal for a seizure disorder. I have experienced SEVERE body and headaches withdrawing from Seroquel. I do not recommend tapering down on your own. I have found that Ambien CR is a great drug. F 35 3 years
7/10/2007
 4  OCD, Insomnia Strange muscle feelings in legs about 1 hour after taking, hungry more often but no real weight gain due to strict dieting. Drowsiness the next morning. 200mg sometimes take 250mg, at night only. Also taking 300mg of Luvox which makes me not sleep but 4 hours at a time, this is why the Dr. is giving me the Seroquel. It also helps with my general anxiety and OCD related paranoia. M 35 5 months
11/4/2008
 4  BP RAPID CYCLING, insomniam anxiety Short term: Side effects are intense-like hitting a brick wall. Dry mouth, difficulty thinking and talking shortly after dosage but the body gets used it at low dosages in particular. Large dosages will put me to sleep unless I am higher than a kite. Long term use has not had any real side effects except for the traditional weight gain with an anti-psychotic. My immediate world credits this drug for turning me into a relatively sane and functioning individual (BP rapid cycler, anxiety, severe insomnia. It put me to sleep at night (with 200 mg) and awake in the morning since it has a short half life. A small dose in the am of 25 mg kept me mellow but not drugged during the day. IT is increased of times when I crack apart and willing to give up the remainder of my life to the drug=I guess it is a balance. It is tauted as a mood stablizer which I cannot necessarily vouch for given that this is only one drug in my arsenal of 6 RX of a rapid cycler. After over 3 years on this drug, I am trying Zyprexa as a new avenue to gain greater sanity since there seem to be few options left and I still could use a bit more...At this moment, I much prefer Seraquel over Zyprexa in terms of sleep and mental clarity but Zyprexa for mood elevation. F 35 3 years
11/21/2005
 4  Major depression - psychotic Very heavy sedation for first few days, not many side effects after that. I found Seroquel to be very helpful. It greatly improved my mood, and also made me feel calm and less agitated - stable. I did find it increadibly sedating for the first few days, to the point where I almost slept non-stop for several days. This quickly wore off, and I found myself able to function normally (though I was always reluctant to drive as I did feel that my spatial awareness was still affected even though I did not feel drowsy). I didn't have any sexual side effects, though soon after taking a tablet the sedative affect would probably mean your libido would be lower for a few hours. I did find that when I was first put on a high dose that it can have a temporary paralysing effect, in that for the first time at a high dose you may find yourself paralysed and unable to move, walk etc. This only occured on my first night at high dosage, and didn't recur again. Overall, I have found this drug to be very effective, and with very few side effects, and it does also help with getting a good night sleep as many have said. M 35 4 months
100 2X day
8/29/2010
 4  Depression, Bi Polar When I first started taking Seroquel I was exhausted....like I had been given a tranquilizer which is why it's advised to take at night before bed. After about four days the sleepiness went away...I have noticed sweating a bit more than usual and definite constipation...I occasionally notice dry mouth and nasal congestion but that is minimal This drug I have to say has really helped me more than any has...I have dreams more than I've ever had before and a definite decrease in my sex drive but I could give a crap if it improves the quality of my life.....I am concerned about reported side effects such as diabetes, high tryglicerides, and high cholesterol. I prob. need to see my doctor and have blood work done... M 35 2 months
7/25/2009
 4  severe generalized anxiety the first week I was a zombie but after about a couple weeks, that tapered off and I was fully functioning. weight gain but not much if you work out a little - I feel like this drug is for me, a miracle. I was taking 6mg of Xanax/day but my thoughts would not stop racing and I felt like I never wanted to leave the house. After a few weeks on this, I was sleeping normal, acting normal. All I can say is that this drug works for me. It's only a little difficult to say how much because I also take 8mg of Klonopin and Effexor XR. I took Paxil once and robbed a grocery store and went to jail. I'm not a robber and it was like the whole thing was an out of body experience. Until I was sitting in a jail cell wondering what the hell happened. Nobody would believe me but I knew it was the Paxil, I just don't go rob stuff, it was crazy. The seroquel noticably leveled me out and works for me. But I swear, the only thing that relieves my most severe depression is marijuana and if that were legal, I think it would be the only drug I would need. M 35 3 years
5/24/2009
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 3  Bipolar Extreme somnolence, restless feet at night, lack of interest and pleasure, blunted emotions, panic attacks, steady weight gain regardless of food choices, temporary worsening of concurrent neuromuscular disease symptoms, gradually worsening memory problems. This drug is very effective in leveling mood (depending on the dose) and preventing psychotic symptoms. The steady weight gain has been horrible, and I've been placed on Actos to try to head off what my primary doctor terms "inevitable diabetes." The really big problem is I am no longer able to sleep at all without Seroquel. Nothing else works. F 35 5 years
8/30/2008
 3  ocd, anxiety, sleep HAIR LOSS; sleepiness; groggy in the morning; some palpitation; extremely vivid dreams it helps with OCD, but you can't miss a dose. F 35 3 months
7/11/2009
 3  OCD, anxiety nightmares, worsening of depression, sleepiness, difficulty to concentrate, impaired memory F 35 2 years
1/19/2010
 3  Bipolar NOS I was first prescribed 100 mg seroquel to lift the depressive part of the bipolar. It had the opposite effect, my depression became far worse, I was drousy all the time and in a fog. Later when the dose was changed to 300 mg XR I noticed the mood lifted. However this was shortlived and the depression returned within 2 months. Now since I'm taking so many drugs I don't know which one is doing what, except I think the seroquel is perhaps responsible for treating the insomnia. I'm on 400 mg of Lamictal, 20 mg of abilify, 30 mg Buspar, and 300 mg of Seroquel XR. You can read my blog where I update my experience with drugs and manic depression.. M 35 15 months
300 mg XR 1X day
7/29/2010

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