SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  PTSD, anxiety, insomnia, depression I have only been on the medication for 3 weeks at 25 mg at night. It is working great for sleeping. My anxiety has gone down some but thinking I may need higher dose. I am also on prozac 60mg and I think the combination is not making me eat more. Great for sleep aid. F 44 3 weeks
4/20/2005
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 4  Bi-Polar Vey sleepy in the morning. Hard to get up no matter how long I sleep. Dry mouth and overall muscle fatigue especially when I wake up in the morning. Also, weight gain. I have gain 15 pounds in 3 months. My insomia has gone away!! I can think clearer. My question to others is whether anyone is also taking depakote? Depakote in the pass caused tiredness and fatigue in the afternoon. It also caused weight gain. Now that I am on both Seroquel and Depakote, my weight gain seems to be faster. No fun... F 44 3 months
2/20/2007
 4  Depression and anxiety Dry mouth and daytime sedation. I have chronic depression and anxiety and, over the years, was prescribed the more common SSRIs, SNRIs, and NDRIs with little to no effect on symptomatology. After beginning Seroquel initially for irritability, anxiety, and insomnia, I noticed improvement in as little as one week. I am approaching my 3rd week on Seroquel and, aside from daytime sleepiness and dry mouth, I am quite satisfied. I have noticed an overall improvement in my mood, ruminative/obsessive thinking, anxiety, irritability, and sleep. M 44 20 days
100 MG 1X day
4/11/2011
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 4  PTSD, Major Depression/insomnia F 44 3 months
25mg 1X day
4/10/2012
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Patient History
 3   hard to find this drug 44
1X day
1/7/2014
 3  schizophrenia lingering grogginess, memory lapses, word retrieval slowness, depression, apathy. it's a great stabilizer over time, but I believe the tradeoff of blunting mental and emotional range, can make it tempting to go off it for a while, just to see if it would make life more interesting. M 44 7 years
50 1X day
11/15/2014
 3  Bipolar NOS sleep Hair loss EXTREME BINGE EATING that progressively got worse Last night I took just 25mg for sleep and within 30 minutes the INSANE urge to eat consumed me and I fought sleep for about 30 minutes to continue eating mindlessly. I hadn't taken Seroquel in months so I was hoping it wouldn't have this effect with just 1 dose. I have taken it off & on over an 11 year period because it is the only sleep med that has worked for me. F 44 4 years
7/14/2009
 3  help with sleep Was prescribe to me to help with sleep when stopping drugs. Does his job for sleeping. I haven't be able to stop it AND sleep more than 3 hours till 8 years. And I have tried ! The longest try was 3 weeks without it, I finally gave up because I only did improve my sleep from 2-3 hours to 3-4 hours I was too exausted at that stage. Took me months the go down to 6,25 mg and sleep enough. I just learned here that stopping seroquel provokes insomnia. All doctors said to me seroquel has no withdrawal effect and all was in my head. F 44 8 years
12,5 mg 1X day
12/28/2018
 3  Recovery from a hormonal illness I needed it to help make me better initially but then needed to get off it to make me well, alot of head rushing, feeling off all the time, extremely tired on waking after alot of sleep, main issues. Helped me in my recovery from a hormonal illness, helping me sleep etc, but i realised I was having side effects that I wasn't getting before and i wasnt able to return to work due to the way I was still feeling so i took a chance and weaned off, wasn't a large amount anyway but since stopping the head rushing has stopped, I dont feel off all the time and im pleaded to say I'm back at work. Trust your judgement if you feel its part helping but part causing problems. F 44 8 months
10mg 1X day
7/17/2020
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 2  Insomnia Tachycardia, Tolerance, Occassional Nightmares, Zombie-like feeling, change in body chemestry. I am also fatigued all the time due to getting less and less sleep. I am never get that good drowsy feeling...just fatigue. I have been on this drug for almost a year now. My psyche prescribed it to wean me off of Temazepan which caused me to "crash" after I had built up an incredible tolerance for due to overmedication by my family doctor. I originally took 250mg but successfully weaned down to 150mg within two months. However, efforts to go below 150mg have been largely a failure. In fact, after relatively good sleep in January-March (averaging about 125mg) I have been experiencing some of my worst sleep since crashing in June, 2008. I cannot sleep without taking this drug. I have not had natural sleep in over 15 months now. Even when I am taking the drug, I no longer feel drowsy and it is taking longer for me to get to sleep. Worst of all, I have been slowly been inching up the dosage past 150mg again just to get even minimal sleep. I do not want to go above 150mg again because of the zombie-like affect it has on me (which is bad enough below 150mg) I only average about five hours sleep even with taking the drug. It has been almost three months since I have had a night of 7 hours of sleep or more. My worst fear is that the longer I take this expensive drug, the harder it will be to ever get natural sleep again. Cleary, taking this drug is clearly not sustainable. Anyone with advice on an inexpensive, relatively safe drug that helped them get off Seroquel? M 44 11 months
5/4/2009
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 2  Insomnia due to other meds This caused me to pass out in a deep sleep and rather quickly after taking it. Once taken, my damn house could burn down I wouldn't wake up. Also, major "additonal" hunger and weight gain, especially late at night. Not much of a hangover the following day. F 44 4 months
??? 1X day
5/4/2011
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 2  depression/ sleep problems I seem to be constantly tired/exhauseted during the day with great difficulty getting out of bed in morning (which i HAVE to do to make sure son gets breakfast & off to school) & often go back to bed during day, sometimes for most of day. Have increasingly found it difficult to get to sleep at night & think i am now dependent on this drug to get to sleep. I need to take it ~7pm & if take it later i get major hangover - grogginess/headaches etc in morning & if I don't go back to bed during day will end up with migraines. If i don't take it, it takes me hours to get to sleep, I get wierd vivid dreams & wake every few hours (sometimes wide awake after 3-4 hrs sleep - feel tired, but can't get back to sleep). Have not been able to hold down a job & seem to just get more & more depressed. I initially was prescribed seroquel when i experienced problems sleeping (after being prescribed venlafaxine for depression). I did not feel well on venlafaxine (up to 400 mg daily), nor lots of other meds, mainly due to constantly feeling tired & unable to cope. Nothing has helped me to get my life back together after initially being diagnosed with Post Natal Depression over 8 years ago. Have recently tried bipolar meds - lithium (Priadel 800 mg) with & without venlafaxine, then Lamotrigine (Mogine 50mg twice daily +37.5 mg venlafaxine) but felt that these meds just dulled my senses & made my really apathetic (not happy or sad, just kinda zombified). I have lots of sinus problems (dust mite allergy + food intolerances (salicylates & dairy)) which got worse post-natal / worse with depression. I take sinus meds (loratidine 10mg twice daily + butacort 100 aqueous nasal spray 2 puffs twice daily). I have just (after reading comments on this website) convinced Dr (4th psychiatrist I've been to) to prescribing an alternate = zopliclone, even thou I have experienced similar 'hangover' effects with it in past, now she says to just try taking 1/2 x 7.5 mg tablet. Has anyone found anything better to take? Any advice/comments would be appreciated, please feel encouraged to email me since I'm feeling very disallusioned & disappointed with Dr's so far. F 44 4 years
25-200mg 1X day
3/4/2010
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 2  depression, PTSD, insomnia intestinal pain, body aches, restless leg, extreme exhaution, weight gain, joint pain, dopey feeling all day, concentration (attention span about 30 minutes at best) I started taking 25 each night to sleep, but had to move up to 50 night. I did sleep and have very vivid dreams (terror dreams) but did not touch the depression. eating like crazy at night, restless legs start 20 minutes after taking. Yes I can sleep but unable to work due to concentration issues and extreme fatigue. Would not recommend for insomnia. I understand it works very well for mania. F 44 3 months
50 1X day
8/13/2010
 2  anxiety insomnia HUGE WEIGHT GAIN. I am weaning off of it. I was at a loss as to why gaining so much weight. I also get heart palpitations. Was put on 100 mg 3 times a day for anxiety. Big mistake. I now take 25to 50mgs a night to sleep. No energy the next day and I only sleep around 4-5 hours. Not worth it. I am weaning off all drugs. I imagine in the next day or two I will totally stop seroquel. Wish I never tried it. Never had the slightest weight problem before. Heart pounding and skipping beats. Can see my heart beat in my chest. Jumpy legs and little interest in doing anything. I feel my energy level returning and my desire to do things. Was given it after ex husband abandoned us. I care for our 4 year old daughter with DS. I will try and report back if weight changes with not taking seroquel. I am not expecting major changes but gradual decreases as I hope my metabolism returns to normal. I eat very healthfully. F 44 9 months
5/23/2007
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 1  Insomnia-PTSD First month was fine. No severe side effects, however did not really help my sleep or constant awakening. By month 3, this drug combined with Lexapro put me in drug induced diabetes and I had gained 40 lbs! For some this works great. Mentally wise, I have no complaints. But be wary if you have weight problems (easily gain weight, overweight or are on other drugs that slow your metabolism). It is only one month I have been OFF seroquel and even though I have been following a medically prescribed diet to the letter my blood sugar is still very high. Have your labwork done monthly! The weight gain and diabetes was not worth it to me. F 44 4 months
12/20/2008
 1  Sleep/mania If I take more than 200 mg, I will fall a sleep fast, but will wake up an hour later with a racing heart. Sometimes, I have to get dressed and run around the block a couple of times. In six years my weight has gone from 145lbs to 206lbs. Currently, I weigh 188. I work in a laboratory. I have noticed that my fasting blood sugars have been creeping up a little higher than I like. For the last several months, I have been very manic, and filled with anxiety. I am taking myself off this drug. In the beginning, Seroquel mad me sleep like a baby.The first night I took it, I fell a sleep on my dinner plate. I have been thinking of quitting seroquel for the last couple of years. I have not been sleeping for the last two years, so the medication is no longer working for the reason it was prescribed. Tonight, I'm going to cut my dose from 200mg to 150mg. I will do this for a week. Then, I will cut my dose to 100mg for a week, and so on until I am off the med in four weeks. M 44 6 years
200 mg 1X day
8/8/2010
Email
 1  Insomnia Want to destroy your brain with this neurotoxicity drug? Should not have been given to me for insomnia. Causes your brain tO shut down serotonin and mOre. Also causes tics and depressiOn. Destroyed my brain. F 44 7 years
50mg
1/28/2012
 1  Aggitation Zombie land, bad dreams, aggression weird drug in general. Didn't like it felt weird , lights are on nobody home M 44 5 days
30mg 1X day
10/6/2012
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 1  Help with sleep,O.D.D., Conduct Dis Could not even stand up 45 mins. after taking med., a ZOMBIE in the morning, hostility, aggressiveness, major mood swings,aggitation. difficulty concentrating, easily confused and frustrated, always hungry, weight gain. My 11 year old son was put on 200 mg. Seroquel at bedtime to help him sleep in the hospital.Then doc.continued it for O.D.D. and Conduct Disorder. When I told the doc. about the side effects he was having, and how it seemed to make him worse, she said it can't be from the Seroquel because it's suppose to help.If she cared enough to look it up,{as I did} she'd know she is wrong.This stuff can/did cause major problems. I am tapering him off..From 200mg. to 50mg in the past 2 weeks and I already see a big improvement. F 44 1 years
4/18/2006
 1  Bipolar mania Brain death--could not think my way out of a paper bag. Zombie-like constant sleepiness. Hideous nightmares. Rage/anger and depression. Enormous appetite, weight gain. Acne. Withdrawal problems. This med is toxic waste! It was supposed to even out my mania, but what it did was steamroll my brain. I couldn't understand anything I read or any verbal instructions people gave me, constantly made mistakes at work, couldn't remember anything. I also had horrid bad dreams that repeated over and over again all night, something I never had before this med. It got to the point I didn't even want to go to bed because I knew it would just be an all-night horror show. I walked around all day in a stupor--I'm not sure I was ever in fact awake the whole time I was on the medication. The only way I can say it helped my mania is because I was too tripped out to care that I was manic. Then the rage set in. I would lose control and go berserk about everything--when my purse fell over the seat of my car, I threw it across the car 12 times and broke a bunch of CD's before I even realized how insane I'd become. Then I started to get depressed on top of that. It made me eat constantly, and I put on F 44 3 months
4/1/2007

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