SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Bipolar Depression and Insomnia Worst drug ever. Takes (3-5) hours to put you to sleep. Than you have horrible nightmares and remember all your bad dreams the following morning. Does not improve depression at all, makes it worse! The XR version will make you completely incapacitated the following morning to the point where you can't even move your body; literally. Completely halts the effect of stimulants like Vyvanse used for major depression and enabling you to get out of bed in the morning. Worst sleep aid on the market and no patient assistance programs exist. Also terribly expensive. Consider another antipsychotic such as Abilify or Saphris, you'll be glad you did. Plus Abilify and Saphris and Vyvanse will give them to you for free if your income is low enough; generally under ($25,000 annually). M 31 2 months
200 MG
2/4/2014
 1  Depression It's blocking my receptors. I am like a zombie, meaning that I am emotionally blunt. I need to know if there are any medications that could reverse the side effects of Seroquel. M 31 8 years
100 mg
7/15/2016
Email
 1  Because the psychiatrist said I experienced seizure of the mouth and jaw. Struggled to breathe and swallow and almost died. Was met with nurses laughing their asses off. It is painful to take. I would rather live in the Santee jail. F 31 10 years
12/22/2016
Email
 5  CPTSD So far I love it. I used to cry every single day from trauma and now I don't. I feel like this pill dries my eyes. Yes it is emotionally blunting but this is what I need. I feel things too deeply. I needed a break from being sad. So far I am pleased . F 32 2 months
25 1X day
8/25/2023
 5  Bipolar 1 While on regular Seroquel: Drowsiness, dry mouth, thirst, rapid heart rate a few hours after taking a dose, confusing moods and thoughts when starting (no more confusing than while in a psychotic manic state), akathisia (very bad at beginning but tapered off), moods swung when morning dose would wear off to night dose, VERY hard to get up in the morning Now taking XR: Drowsiness, rapid heart rate, thirst, sexual dysfunction Started off at 100mg in the morning, 200mg at night. W/ every last ounce of sanity left while in a psychotic bipolar state I stayed on the med. My thoughts became organized within a few weeks but took a good 2-3 full months for the med to really shine (in a positive way). My moods however wouldn't stay stable in the evening so doc started XR. Mood is now stable throughout the day. Many complain about fogginess or being tired. XR makes me drowsy only when taken at bedtime, but unlike most people's opinions I've read, I LOVE this about Seroquel. When I want to sleep, I get good, solid sleep on a regular pattern. Much easier to get up in the morning. There is no generic equivalent of the XR, it is very expensive. Like any medication it is a risk versus benefit. For me this medication is worth the risks and is a blessing. M 32 9 months
300 1X day
1/7/2015
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 5  Bipolar Disorder I weight gain, fatigue or dizziness if I increase the dose too fast, revved up right after I take it, constipation I get every side effect from drugs and seroquel has been (relatively) side effect free for me. I feel more normal than I have in YEARS when taking this drug. It has been a godsend- I have been through so many drugs that gave me incredible problems so severe I was disabled from the side effects. Seroquel has helped my anxiety, my insomnia, my mania and mixed state episodes and also my depression. I was on Risperdal and became so anxious I had constant long lasting panic attacks I was rehospitalized. It also made me very very fidgety. They gave me Seroquel to counteract it and it worked like a dream and I have been on it ever since. I know the risks of weight gain and diabetes. But my weight gain hasn't been as bad as most people's on it, my blood sugar has been normal so far but I keep an eye on it and even though some of the side effects are annoying, it is much better than the hell I went through before I found this drug!!!!!!!!!!!!!!! F 32 3 years
12/19/2009
 5  Anxiety I liked it, I have never done hardcore opiates, until I tried Seroquel. It made me nod if I was not moving around. I recommend it for anyone who wants to nod without the itchiness. I do realize it is not an opiate, I guess? M 32 2 days
7/10/2008
 5  bi polar, insomniac heavy hangover effect every morning that subsided after about a week. deep needed sleep. racing pulse during day- subsided. sweating- subsided. gained 5lbs in 1 week (6'3" 162lbs to 167lbs, but this was a plus because I've tried for years to gain weight) better appetite, emotionally i was able to think but my feelings were suppressed, which in my case was a bonus given my temper previous to seroquel use. This med allowed me to sleep for 8-12 hours, comapared to the usual 3 or none a night. Also allowed me to stop smoking pot (which no longer does much to me) and drinking vodka in excess. So I did not experience a dumb effect (I was already dumb daily from self medication of high grade pot/vodka)I felt clarity after waking up in the morning (which could talke a couple hours from the seroquel sleep) probably which came from not smoking pot or drinking but it was worth it until my insurance wouldnt pay for it then I had to come off it which was depressing so now they put me on zyprexa which is no good for my insomnia but feels like a party drug tome me unlike seroquel where i only craved it at bedtime. M 32 2 days
7/12/2007
 5  bi polar/anxiety/insomnia hangover (not as bad as an alcohol one) muscle spasms in shoulder strong pulse sweating these aren't as bad as they sound and they come and go- the sleep I get is well worth it. The hangover starts to get less and less each day. I dont feel like a zombie because I've already felt like one from the booze and weed so this is replacing that and is much less zombiefying than walking around drunk + stoned was. Say goodbye to severe insomnia and also to your morning job. This sht is a freakin heavy duty tranq but you won't hear me complaining about that. Its like a xanax but less of a high, though more sedating, therefore you dont really crave it to party with like you can crave benzos. The hangover is heavier than a benzo but is shorter lasting only 1-3 hours rather than 5-10. Therefore your not trying to hair the dog the bit you with it. I really like how I can maintain self control and only take the required dose for sleep rather than binging a whole months 'script in 3 days like I would with benzos. I ended a 15 year pot habit and 4 year vodka habit with this med therefore i rated it at 5 but would have rated it 10 if i could. M 32 14 days
7/23/2007
 5  schizophrenic Very sleepy for the first month. Since then no side effects of any type. Thanks to Seroquel I've been stable and symptom free for five years now. M 32 6 years
7/26/2003
 5  situational stress and bad sleeping sleepiness seroquel is best of the worst. at least it works well for me, thought it was clear overmedication and it sucked me into a life-long psychiatric patient. you cannot withdraw this drug easily/safely unlike some other meds (relora?/nmda antagonist? + beta agonist etc). M 32 4 years
400 1X day
7/25/2012
 5  Abnormal Space cadet none this drug put me back on planet earth from space and beyound F 32 3 days
1/13/2007
 5  Anxiety After I took it I began to feel extremely tired and lifeless. That feeling kicked in around 20-30 minutes of taking my pill. I know that I wouldn't be able to stay awake if someone paid me serious money. I don't suggest driving after taking it. You will be sleep behind the wheel in no time. I had issues with my mind racing all of the time, and had a hard time going to sleep. I had already been prescribed Xanax, but for some reason it didn't stop the severe twilight zone feelings that I was having. I remember thinking that I was losing it at times. My doctor prscribed me 50mg of Seroquel, which helped out tremendously. I was able to sleep, and found myself not being worked up about small things. I also lost the being in the twilight zone feeling that I was experiencing. I think that Seroquel was a life saver. I am no longer taking it because I am pregnant, but for some reason I am doing alright. I think it is because I am happy and very focused on my baby. F 32 1 months
4/6/2007
 4  severe insomnia, BP2, slept/ate like baby pig.. Gained 10lbs(a plus for my scrawny ass) Apathy(is this really a bad thing?) Loss of proper motor function (overdose of 600mg instead of my normal 400) My kill count went up on Battlefield 2 (my aim got steadier) Friends/family no longer walking on eggshells around me now.. Nightmares squashed.., I can finally eat like a REAL american... i used to do drugs for an adventure in my mind... now i'll just skip dosage of sero for that effect. i actually plan and look forward to the days that I will skip the sero.. i dont feel like a zombie more like a robot on 2/3 charge but just skip a dose and remember who you truly are.. M 32 3 months
10/13/2007
 4  Bipolar Extreme weight gain! I went from 126 to 142 in a month and a half. Is this normal?? At first I expirienced feelings of not being able to move my arms and legs once i was in bed. I was on too high of a dose, 300 mg. Now I am on 100 mg at night. I started taking seroquel in December My doc says that it doesn't cause weight gain, but after reading all the comments I am going to give him a call. I love the med though. I have never slept so well in my life. Plus, the constant crying has stopped almost all together. But, this weight gain is making me very depressed and I don't know if it is worth it. I have changed my diet and have started running every other day and there has been no change. I have actually gained two more pounds since then. Any advise? F 32 2 months
2/15/2006
Email
 4  insomnia, anxiety Very little side-effects. Feeling tired. Some blood sugar issues. Withdrawal can kill. Monitor your blood sugar (and insulin!) levels. 5-HT2A and cardiovascular tissues. Excess ACTH and cortisol and brain activity. M 32 3 years
400 1X day
9/30/2012
Email
 4  Bipolar 1 I have been takig this drug for a long time. Initially, I was taking a high dose (1000 mg). It helped me fall asleep and stay asleep, though it left me very foggy brained in the morning and while trying to fall asleep, my legs would feel restless. Gradually, I have lowered the dose over the years, so I now take 300-400 mg nightly. I think this drug has been very helpful for me. At times, I have tried to wean myself off of it and find it very difficult. I don't sleep very well, if at all and I experience nausea and diarreah. And so I continue to take it. Have not experienced weight gain from this drug. I would like to know if anyone succesfully quit this drug. I am worried about long term side effects. I have improved my diet over the year by eating whole foods and taking supplements. I've eliminated most processed foods and alcohol. I also exercize regularly and practice yoga. I've noticed an increase in side effects and I wonder if my body is becoming more sensitive to the drug. I also take lamictal and lorazepam. Thank you. F 32 9 years
300-400 1X day
10/20/2011
Email
 4  bipolar - episode of mania Drowsiness, difficulty focusing, no motivation, can't stop eating It does seem to work it brought me back to earth. That having been said I'm going to stop taking it the side effects are too much especially the lack of motivation and drowsiness. It's a real effort to accomplish anything significant which is a bit of a problem. M 32 45 days
100 1X day
6/17/2010
 4  bipolar 2 very drowsy, dizzy. slight hangover effect in the morning, but went away with time. I had a brief worsening of mania symptoms for 2 days. Mania gradually disappeared altogether. Great for my sleep issues! F 32 30 days
7/15/2004
 4  Augment excitability from Lexapro Very minimal at 75mg per day. Great augment with an ssri. Works best as an augment. Good med. M 32 1 years
6/28/2004

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