PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  RA Horrible nightmares at first, gone after about 3 months. Have had some skin rashes, but not sure it's the Plaquenil, and have some hair loss/scalp problems. Again, not sure if it's the drug. Ditto on all the gastro problems everyone mentions: gas, bloating, diarrhea from time to time. Some fatigue, but it's much better than when I was in the middle of a flare. Very satisfied with this drug so far, but have been worried about my hair loss and scalp irritation. I've been basically pain free since it started working (it took about 4 months to really notice). I would be scared to go off of Plaquenil because I feel like I did before the RA. F 56 3 years
7/20/2009
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 5  SLE None I've been taking Plaquenil for three years and have not had any noticable side effects. It helped with joint pain but did not help much with muscle pain or fatigue. I do feel much safer on it since it inhibits antibodies. F 46 3 years
9/24/2008
 5  UCTD None I have been very satisfied with this medicine. It has helped the muscle and skin pain tremendously. F 27 3 years
10/12/2001
 5  SLE CARDIOMYOPATHY, rare side effect , I now have severely hypokinetic inferior wall of my heart F 45 3 years
10/27/2003
 5  rheumatoid arthritis Bit mushy thinking M 55 3 years
12/6/2007
 5  RA and Sjogrens In the beginning I had the stomach pain but my doctor ordered Omeprazole and I have not had any problem since. I will get itchy at times. I also take Ibuprofen 400mg TID, Tramdol 100mg about every 4 hours, Vitamin D supplement. It changed my life. I was in bad pain for about 8 years before this. It took a little while for meds to kick in (3 months). I lost 40 pounds ( but that was good) I was overweight. I take my meds regular and on time. If I get off schedule it does not work as well. At bedtime, I take 100mg of Tramadol, 800mg Ibuprofen and I sleep like a baby. I take the Plaquenil 200mg in the morning. Take at the same time every day and keep schedule. Be patient and give it time, it is worth it. Check eyes yearly. Get doctor to give meds for stomach pain. F 53 3 years
200mg 1X day
1/18/2012
 5  arthritus My first medication was prednesilone which while it worked ok it had side effects. My testes shrank to the size of grapes and I gained 20kg of weight, this went on to cause heart disease. Plaquenil has worked really well with only some itching when I first started taking it. Now I have concerns that I am experiencing muscle weakness and tremors particularly in my right arm M 55 3 years
20 2X day
9/16/2010
 5  Sjogrens When I first started I had lots of gas and digestive issues but taking it with a fatty food really helps. Got rid of my fatigue and swollen achy fingers. Really a wonder drug for me. I make sure to get my eyes checked every 6 months and use the amsler grid in between eye appointments F 56 3 years
200 2X day
7/21/2010
 5   dizziness when first starting the medicine has made my Bechet's symptoms all but disappear. I love it! F 33 3 years
20 mg 2X day
4/21/2010
 4  Eosinophilic Fasciitis/UCTD Had some appetite loss at first, took some getting used to. Some activation of Psoriasis in several different areas of the body. Not unbearable in that regard, but annoying. Tried taking Methotrexate with the Plaq to control psoriasis, but that didn't seem to do anything Generally, Plaquenil has been very helpful. I have had quite a bit of wrist and elbow pain and constriction (bad but not severe), and the pain has definitely eased with the plaquenil. The flexibility really has not improved much. Still, I seem to feel much better when i am on PLQ than when I am not -- particularly with regard to morning wrist/elbow pain. M 44 3 years
200 1X day
3/1/2010
 4  Systemic Lupus and Sjogren's Many brown FRECKLES all through my mouth and lips (hate this side effect), darker fingers and thinning hair (hair loss could be due to the lupus or just aging), and GAS. I get my eyes tested every six months. No eye problems detected. I had a life threatening flare of lupus and TTP (platelet and red cell disorder) four years ago. Went on Plaquenil for two years along with Prednisone. Went off both w/doc's okay when I appeared to be in remission. After one year off Plaquenil, I developed Sjogren's Syndrome, Raynaud's and more fatique and joint pain. I'm back on it at 200 mg/day. I credit Plaquenil with reducing my symptoms and allowing me to get through the summer without extreme light sensitivity, rashes and weakness. I don't have to take Prednisone now. F 45 3 years
2/23/2005
 4  RA & Antiphospholipid none at first. Now at 3 years, damage to left eye. Stopped medication. Plaquenil has given me about 75% improvement for pain and mobility. I hope they can give me something that works as well as the plaquenil has. F 43 3 years
11/18/2002
 4  UCTD, Early stage SLE Initial cramping, diarrhea, headaches, brain fog. Plaquenil benefits started within weeks of taking it. Pain level dropped but does increase during flares where Plaquenil doesn't help as much. Will keep on it as it's probably kept my early stage SLE from progressing, according to my Rheumy. F 51 3 years
9/23/2008
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 3  UCTD, A/I thyroid, anticardiolipin Weeks of horrible itch rash/hives, trouble w/short-term memory and concentration.(Have seen internist, dermatologist, and rheumatologist, w/biopsy= It has helped with the pain and possibly with the profound fatigue (have other conditions also that contribute to that), but was off Plaquenil a couple weeks and eventually the rash was beginning to clear; back on it for three doses (200mg) and rash/hives reappearing. F 62 3 years
6/18/2004
 3  sle thinning hair, gas, extreme generalized itching, increased facial rashes, and lately fast pulse and a feeling of heart racing, and the problems with fatigue continue Have some people had success with periodic trials of taking the drug? F 60 3 years
12/20/2004
 3  Juvenile Rheumatoid Arthritis dizziness, stomach upset, vomiting, horrible itching! My daughter had been taking Plaquenil for 3 years now. It has been the drug that has helped her knees the most, but now she has been experiencing serious nausea and vomiting, evey other day at school, and is missing a lot of school due to the vomiting. She has eye exams every six months, no problems there yet. After she gets out of the shower or bath her legs and arms itch uncontrably, until she is crying, the itching is so intense. The Rhuematologist and Pharmacist keep telling me that these side effects can't be from the plaquenil, but the only other thing she takes is Tylenol, and all the lists of side effects say these are possible side effects. I would be interested to hear from others with the same side effects, especially in kids. I am not sure at her age that the side effects are worth the help for her knees. F 35 3 years
11/20/2006
 2  lupus and sjogren's Memory loss, lack of concentration, blurry vision, my skin changed colors, and diarrhea. The doctor kept on saying that it was not the plaquenil. They wanted to give me namenda (for alzheimer). They said that I had cognitive damage. They sent me to therapy. I knew it was the plaqenil. As soon as I stop taking it, I was able to follow instructions on my job. I do not feel lost. My vision is better. My stomach is practically normal, even with Sjogren's syndrome. According to my doctor today I would be disabled taking more than 10 pills a day. I stop the medication with NEW doctor's approval, and I am doing great. People should find out if they really do worst without it. Temporary it can be taken, but all the time in a lot of case I do not think that is necessary. F 49 3 years
3/30/2007
 1  lupus Bad mood swings,anxiety,night sweats,insomnia,headache,bloating,wind,sensitive to sunlight,hair thinning and getting lighter,fast heart rate,difficulty breathing and chest congestion,pain in arms and lower legs. Absolutely horrible drug. F 44 3 years
400mg
6/29/2016
 5  RA none, although my hair has gotten wavy. wonder if it is the medicine or just being post menopausal F 58 3.5 years
10/9/2003
 3  Rheumatoid Arthritis Initial hair loss (stopped after 6 months), skin hyperpigmentation I noticed a difference after about 3 months of taking it, but it took 6 months to be fully effective. I have been taking it for 3.5 years (with 1 year hiatus due to pregnancy). It worked great for a while, but now it is starting to fail. I'm a little disappointed that I can't use it any longer since it was so easy to pop a few pills with very minor side effects. F 32 3.5 years
400mg 1X day
9/8/2014
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