PLAQUENIL Reviews (HYDROXYCHLOROQUINE SULFATE)

Average Rating: 3.2 (667 Ratings)

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 Type: Rx Drug

  

PLAQUENIL  (HYDROXYCHLOROQUINE SULFATE):  Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. It belongs to a class of medications known as disease-modifying antirheumatic drugs (DMARDs). It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works.    (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PLAQUENIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PLAQUENILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  arthritis There were no discernible side effects. This drug did not do anything for my arthritis. I ran out and had to wait a couple of days to get more. During that time without it, I didn't feel any different than when I was taking it. Have stopped now to try Arava. F 36 7 weeks
6/5/2008
 1  Grannuloma Annulare none that I am aware, but have to take quarterly eye exams. so far I've seen ZERO benefit from this medication. In fact I dare say my condition has worsened. M 48 7 weeks
200 mg 1X day
2/8/2010
Email
 5  UCTD No side effects so far (maybe a little gassy at first but that is inconsequential as far as I'm concerned). Plaquenil (the generic) has given me my life back. I could not tolerate the first drug prescribed for UCTD (one dose and my eye started swelling). With Plaquenil the pain is almost gone but most importantly the fatigue has subsided immensely. My personality is back to where it was before the UCTD started taking over my life. I just hope the side effects stay away and that my 6-month eye check-ups reveal no change because as far as I'm concerned this is a wonder drug. F 59 8 weeks
200 2X day
8/3/2010
 3  RA mild dry eyes I have been taking plaquenil for almost 2 months along with 10mg of prednisone. I stopped the prednisone for about a week and had my symptoms return with the same severity as before medication. Still waiting for it to kick in. M 38 8 weeks
7/13/2007
 2  SLE gastro upset, reflux, extreme nausea, itching skin, upset stomach, enhanced smell, loss of appetitie I feel disheartened I am not seeing any clear results yet. Taking 200mg twice a day. Still not pain in hands, wrists,and knee and feet. Hoping this might go in next few weeks. Very hard to tolerate side effects F 35 8 weeks
6/29/2007
 2  Yes I was taking the generic Plaquenil 200mg per day. It upset my stomach so I stopped after 8 weeks. My doctor wants me to start the Brand name. Its been two weeks and I feel much worse after I stopped the drug then before I ever took it. My upset stomach will not go away, I feel lightheaded and am very tired. I did not have these symptoms before I started on this drug. I think it really messed up my body. I was told I have Sjogrens. Very frustrated at this point... M 57 8 weeks
3/14/2009
 1  active rheumatoid arthritis Sore throat, led to not eating much because of swallowing, nausea, food didnt want to stay down. Day of hospitilisation, diahorrea, vomiting, weakness , dehydration. This is written on behalf of my mother. Have had the arthritis for many years, told it active in October 2006. Saw speciialist Nov 2006. Had notice lumps in fingers starting to disappear in December 2006 but could of been result of other new medication at the same time. Admitted to emergency January 2007, because of weakness and diahorrea. Very dehydrated. Tests completed - small stomach ulcers, and severe Thrush up through chest and throat. Symptons only occurred in a matter of days, sore throat was checked by doctor prior, thought to be inflamed. Severe symptons only come on within two days and led to my death within a week. Was told amount of dosage was too high for this age, 200 mg.( 2 tablets) Dosage recommended for 25 yr old. F 76 8 weeks
2/5/2007
Email
 1  active rheumatoid arthritis Sore throat, led to not eating much because of swallowing, nausea, food didnt want to stay down. Day of hospitilisation, diahorrea, vomiting, weakness , dehydration. This is written on behalf of my mother. Have had the arthritis for many years, told it active in October 2006. Saw speciialist Nov 2006. Had notice lumps in fingers starting to disappear in December 2006 but could of been result of other new medication at the same time. Admitted to emergency January 2007, because of weakness and diahorrea. Very dehydrated. Tests completed - small stomach ulcers, and severe Thrush up through chest and throat. Symptons only occurred in a matter of days, sore throat was checked by doctor prior, thought to be inflamed. Severe symptons only come on within two days and led to my death within a week. Was told amount of dosage was too high for this age, 200 mg.( 2 tablets) Dosage recommended for 25 yr old. F 76 8 weeks
2/5/2007
Email
 5  for hand and feet pain None that i noticed It is not supposed to help my condition(small tissue neuropathy) but i started taking it bacause i was misdiagnosed for arthritis and nothing worked.When a neurologist figured it out it was neuropathy he said to start Gabapentin which i did and it helped.later the neurologist and rhemotologist said to stop placquenil.After 6 weeks off the Placquenil my discomfort got a little worse so i just went back on it for a 3 month trial. i am still taking the Gabapentin M 65 10 weeks
100MG 1X day
5/26/2011
 2  Lupus Hair loss in one area of my head, stomach cramps, gas, itchy skin, blurred vision, terrible nightmares, hallucinations in dark/poorly lit rooms, migraine after I didn't take it for a couple of days. I have a lot more anxiety and cry over ridiculous things. I feel like I did when I was pregnant, and I'm definitely not pregnant. This doesn't seem to have helped. I don't have an actual dx but my rheum wanted to try this since lupus seemed most likely. While I do have a little more energy, ritalin works better! (My pcp started me on low dose of ritalin for the fatigue) I see rheumy tomorrow and I'm going to tell him I don't want to take this anymore. The mental side effects are not worth the little bit it does physically. F 24 11 weeks
10/23/2008
Email
 3  Sjogren's 200mg twice a day caused low blood pressure, poor circulation in extremities, extreme heat radiating from my body that woke me up in the middle of the night, frequent urination, and heart palpitations. Most side effects began at week 10 of the dose. Stopped meds for 30 days, most side effects halted quickly, palpitations slowly decreased but never went entirely away. Went back on at 200mg once a day, palpitations increased in frequency during week two. Not sure if I'll stay on it. Overall the drug did reduce my aches & pains, dry mouth, and increased my energy. I'll have to weight the pros and cons of staying on it. F 32 12 weeks
7/28/2009
 2  RA Break-outs on strange parts of my face. Didn't control my RA in conjunction with Remicade treatments. F 26 12 weeks
5/2/2009
 5  Lupus Have had decrease in appetite and some stomach upset but that seems to be subsiding, otherwise, this medication has done wonders for me, almost ALL of my joint and tendon pain is gone, my energy is returning and I feel like I did long before this disease took over my body. F 37 1 months
5/27/2009
 5  Inflammatory arthritis, fibromyalgi Gas, gas, gas, dry eyes. Developed allergy in form of all over body rash. This medication was life changing for me until I developed an allergy to it. It started working in 3 weeks, and I felt 10 years younger. I was able to play with my kids, had more energy about everything in life. I hope your result is as good as mine, minus the allergy! F 37 1 months
2/1/2005
 4  SLE Gas,Tiredness,Dizziness,Wieght loss. I have gotten alot of relief from joint pain by taking this medication. I can deal with the side affects if I can just get rest at night from the joint pain. Im a mother of 2 boys I need all the rest I can get, LOL. F 32 1 months
10/9/2007
Email
 4  uctd/lupus Plaquenil was starting to help with my joint pain. Unfortunatly I developed a rash, hives and difficulty swallowing. I had to stop taking it. I was taking the generic brand. Within a few days of stopping the meds my knees once again felt like they were hit with a sledge hammer. :( Hoping I might be able to take the name brand. F 40 1 months
200 2X day
1/27/2011
Email
 4  Skin lupus Stomach upset I haven't felt this good in years. Face is clearing, joint pain eased, wake up in the morning and feel normal. It's even helping with fatigue. A miracle & I have tried everything. My immune system was totally hurting me everyday. F 48 1 months
200 mg 2X day
8/13/2014
 3  Rhuematoid Arthristis Only have minor stomach cramping if I do not eat within a short time after taking this. Other than that, do not seem to have any other negative side effects so far. Just a few days ago I started being able to tell that I didn't ache as much in the mornings. My Rhuemetologist did advise that it may take up to 8 weeks for postive effects to be seen, so I'm happy that I'm seeing some positive results as early as 3 weeks. Hope there's more to come as time passes. Seem to have more energy too, so that's a definite welcome change. F 45 1 months
200 MG 2X day
3/15/2011
Email
 3  Connective Tissue Disorder Gas, hair loss/thinning, lack of sleep, fatigue, vivid dreams, bouts of depression I'm worried about my eyes after reading all the comments. I had a baseline eye exam and all was well. I have noticed my muscles in my thighs are much better in the morning. I still have muscle weakness and pain. I'm also taking 20 mg of prednisone daily. I'm on a low fat, lower sodium diet which is helping keep the weight down, but I still feel fat. F 37 1 months
9/25/2007
Email
 3  Inflammatory Arthiritis Diarrhea is really the only symptom I have experienced. I have bad joint swelling in my knees, spine and wrists. This medication has slowly been working. I dont feel 100% just yet, but I can tell something is starting to work. I have had only one flare since taking this medication. I hope as the months progress I will feel even better than now. F 28 1 months
5/20/2009

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