PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  chronic fatigue, fibromyalgia Mouth ulcers,ear pain,eye pain,skin pain,sore throat,all on left side of head.Thougt I had the flu.(200 mg) Headaches, chest fluttering, left arm pain,tongue biting, bones and joints in legs hurt SO bad that I was tossing and turning all night in pain, EVERY night. After 11 days symtoms continue to worsen. I can't stand the increased pain and will have to stop it. Also felt extreme exhaustion and depression. No drive to do anything. Mid-day crash and burn. No recovery. I also have ADHD. It actually did help with staying on task and not forgetting every single detail of things I needed to do, but affected my memory badly,ie., I know I have an SUV in my garage, but can't remember the make and model... I think it'e another drug failure for me. I had to undergo interferon therapy over a year ago and though Hep C is gone, my life is very painful and tired. So much for this one. F 51 11 days
10/5/2008
 3  ADHD, Predominantly Inattentive Typ First day smelly urine and slight palpatations I just added it to my personal cocktail that I take for bipolar ll and anxiety. The complete mix includes, seroquel,lithium lamictal, buspar and now provigil for recently diagnosed adult adhd passive. It has not triggered bipolar cycling nor have there been any drug intereaction issues. I have been able to read the New York Times several days this weeks but I still don't know how effective this will be in the long run. F 54 13 days
4/28/2008
 5  Relentless fatigue! It takes me a bit more time to get an erection I was on Prozac 60mg/day. It helped take the M 34 14 days
12/17/2004
 3  Sleep disorder / for concentration After two courses of 10 tables over 3 weeks: 1) improvement in concentration and focus (onset: 1-3 hrs after dose Duration: 6 - 8 hours) per 100mg tablet. 2) Could sleep right through nights without sleeping pills 3) strong metallic smelling urine 4) lost the euphoric feeling after exercise (endorphins affected?) 5) mood and thinking changes (more aggressive) unsatisfying thoughts 6) I am currently off the medication (about 7 days) and I think now my motivation is 25 - 30% worse then it was prior to taking the drug 7) loss of appetite whilst on the medication but my appetite has returned over the last few days. I am going to get another course and note the differences and reassess my intake. M 27 14 days
100mg 1X day
10/9/2014
Email
 2  depression, fatigue more tired, sluggish, mind-mush, unable to get anything done, itchiness, diminished appetite (good for me!), heart palpitations morning alertness (good), then rebound effect....after a few minutes of alertness, it then felt like it sucked all the energy out of my brain, thereafter for the rest of the day. Taking an additionsal dosage (50mg a.m.) another 50 in afternoon only made me jittery and uncomfortable, and still sluggish. Feel better on my favorite drug: caffeine...... F 46 14 days
7/15/2006
 1  Excessive daytime sleepiness Euphoria first day, headache second day, then arthalgias, fever, flu like symptoms and a CRASH with increased somnolence, hypnogogic hallucinations, emotional lability, increased anxiety. Effects were reproducible! I thought that I caught a virus from my kids @ first, but on re-challenge, same thing with frank meningitis like symptoms, sore toungue with scabby little lesions like Coxsakie virus (Hand-foot-mouth), and then sleepier than ever with bad dreams (Fell asleep watching the Cubs last nite, thought it was another drug-induced nightmare, but it was real!). These feelings cleared up several half lives after my each of my 7 day free trials. I don't want to risk it again (fool me once, shame on you, fool me twice, shame on me). FTR, I am an MD and also on prozac & trileptal & propanolol for depression/generalized anxiety disorder. M 49 14 days
10/5/2008
 1  hypersomnolence severe dyskinesia - jaw clenching and teeth grinding very erratic results at 100 and 200 mg doses. Most of the time it did not seem to affect my sleepiness; once I was "wired"for 36 hours. The dyskinesia never let up. F 69 14 days
9/13/2007
 3  sleep apnea headaches, all over itching M 48 18 days
9/2/2008
 3  Disrupted Sleep Patterns Extreme Nausea day 8. Non-stop ringing in the ears day 11 and beyond. Thought I had a brain tumor due to the ringing and vertigo that was actually the nausea. I am nap free, but spending my old nap time trying to fight the stomach pain and annoying ringing ARG F 38 19 days
6/10/2008
 5  apnea, fatigue, depression Have had chronic depression for decades and none of the many antidepression medications I tried had any positive effect except for Parnate, an MAOI, whiuch was somewhat effective. I finally stopped taking Parnate to try other avenues. (MAOI with Provigil is considered risky and untested.) Also have sleep apnea and have used CPAP every night for 10 years. Largely side effect free except slight throat irritation which is surprising since my CPAP has an otherwise effective humidifier. First two days were amazing. Became downright enthusiastic and perky after many months (years, actually) of depression, daytime fatigue, body aches, repetitive yawning, suicidal thoughts, etc. Taking 200 mg in morning. The amazing high subsided over the next ten days to the point where I now feel pretty normal which is a great feeling. I am able to get things done, get out of the house more, interact with people more. I am also motivated to eating healthier which has led to about 5 pounds weight loss in three weeks. M 59 20 days
6/6/2005
 3  Idiopathic Intracranial Hypertensio drowsiness for first hour after dose, hot flashes, excitable heart, sleep disturbances, mild headache Provigil is an okay drug. The side effects weren't so bad for me, but the actual effects weren't much, either. I did feel better than before, but while Provigil was able to give me the PHYSICAL energy to stay awake, I still felt mentally drained most of the time, had a hard time concentrating as usual, and wanted to sleep even though I didn't feel the urgent NEED to fall asleep. I still found myself having to supplement with caffeine. It was semi-helpful, but not what I had expected, and at such a low dose, I wouldn't really consider it effective. I may request a higher dose in the future. F 18 20 days
100 MG 1X day
3/5/2013
 1  Sleep Apnea Worked for first couple of days and then felt extremely tired and nothing worked. All I wanted to do is sleep. Could not function. Tried Nuvigil and the same, so it's caffiene for now. M 52 20 days
200 1X day
8/24/2012
Email
 5  Narcolepsy Headache, ONLY two times and those were days that I did NOT hydrate with water. Slight dizziness when getting up quick. Midfinil has kept me awake during the day and has kept me focus. I still yawn at times, but I am able to focus on work, school, and talking to others without being extremely tired or falling asleep! I am better focused and better organized. I dont take it on days I am not doing anything but lying around bc I dont want to get used to it and I dont want to become addicted. I dont want to have to increase my dosage within a short amount of time. F 29 21 days
100 1X day
10/3/2014
Email
 5  Study aid No trouble getting to sleep when I wanted to. I have never experienced such high levels of focus and concentration as when I have been taking modafinil. The confidence it gave me when revising made me feel like nothing could stop me getting the grade I wanted. I would be getting through a workload five times as big as I could without it and just reading, learning, understanding and applying everything so very easily. Incredible drug. No side effects. M 21 21 days
200/400mg 1X day
7/4/2015
 4  chronic fatigue, apnea odor to urine, morning rush, insomnia if taken too late in the day, insomnia if taken with caffiene, weight loss, loss of appetite, abnormal bowel movements, unusually high heartrate. some of these symptoms slowly decreasing with time. definitely helps! i'm able to stay awake and feel alert much more during the day. i used to have such a hard time concentrating i couldn't read to study for school but now i'm able to. the side effects can be annoying sometimes and the drug is expensive but well worth it. F 19 21 days
11/20/2005
 4  Fatigue from Rheumatoid Arthritis Slight headache Worked great for the first week. I take 200mg in the morning. Then I added a 200mg caffeine pill twice a day and it started working great again. I feel more alert, better able to concentrate, more active in the evenings. F 48 21 days
6/21/2006
 4  to avoid day time sleeping M 64 21 days
5/18/2002
 3  chronic fatigue None whatsoever This drug may work well for some, but for me, at 200mg a day it was rather diappointing. I could hardly notice any effect at all. I would do just as well by drinking a cup of coffee or taking a caffeine pill. I probably ought to try a higher dose and see if that helps more. M 54 25 days
3/13/2007
 1  narcolepsy Severe red rash with hive-like bumps on legs and arms that lasted for a month. Skin on legs turned purple red in certain areas. Left leg swelled. Skin peeled as red bumps subsided. I have become intolerant to heat and have perfuse sweating. Capillaries on lower legs have become more permeable which cause some veins to dilate and I have to wear support socks. My narcolepsy has gotten worse and I am totally exhausted most of the time. I have never had such a severe reaction to any drug in my entire life. To me Provigil is like taking poison. It may have even permanently damaged my hypothalamus and what else? M 65 25 days
7/13/2007
 2  hypersomnolence The first day was great. I felt like I had a new lease on life. Second day was okay but not as good as the first. On the third day I noticed a slight rash on my lower legs. On my inner thighs there was a large area that was red and chapped looking. These symptoms would wax and wane. And they would intensify if I took an extra 100mg to get me through the day. The symptoms never got unbearable. But very close. I only took it for one month since it was nowhere near as effective as I expected, cost was $380 (not covered by insurance), and gave this side effect. Now one month later, I still have the same symptoms. If it works for you, great. But it turned out to be more of a hassle than it was worth. M 30 28 days
1/15/2009

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