PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Multiple Sclerosis headache at full dose, high blood pressure, soft stools Wonderful. This has given me the chance to work again and enjoy many things. Still tend to schedule work in the mornings due to fatigue that used to take over - becoming completely drained and unable to get up. Now I can go to the store or do an errand after work. 200 mg gave severe headache one day blood pressure systolic was 40% higher than normal! Now 100 mg in A.M. and maybe 50 mg afternoon if needed for night activities. Good sense of well being. F 50 2 years
1/14/2008
 5  MS fatigue and cognitive problems None This drug has saved my life. I was diagnosed with MS 9 yrs ago and fatigue was getting to be a real issue for me. I was also having trouble focusing on anything. Provigil allows me to take care of all the chores around the house, and focus on college studies too! I don't take it every day, usually 3 times a week, and never two days in a row. Love, love, love it. F 45 2 years
8/2/2007
 5  Excessive Daytime Sleepyness None; it's an amazing medication! **** ALERT ******: I have been on provigil for almost 2 years with no complaints. I was considering taking Birth Control Pills or a Nuvaring and found out that Provigil totally removes the effectiveness of Birth Control Meds!! BE CAREFUL! Even if you discontinue Provigil, BC will be ineffective for ONE MONTH!!! F 44 2 years
8/16/2007
 5  MS Mild headache. Taken for control of fatigue due to MS. This drug has truly changed my life. I take two-hundred mg daily and i can go all day, with no gitters. I have ran two marathons since being diagnosed with MS- couldn't have done it without Provigil. M 36 2 years
9/1/2007
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 5  Fatigue caused by multiple sclerosi If I forget to take it in the AM, and take it in the afternoon, I have a hard time getting to sleep. I am also noticing something like a Like others here, I had an initial zoom from this drug. I had the energy I had when I was 25, before MS. That wore off, but one of the best aspects of the fatigue-fighting effects of the drug were my ability to finish things I started, due to an improved energy level. It has bought me 2 to 3 hours per day that I used to spend on a non-negotiable nap. If I forget to take it, I tank. F 50 2 years
3/27/2005
 5  shift work sleep disorder Excitablility. A miracle drug. I was prescribed this medication because of excessive sleepiness during my 10 pm to 6 am work shift and sleeplessness upon going to bed. Not only has is helped me regulate my sleep/wake cycle it has also helped cure my major depression. I suffered for most of my life from crippling depression. I have been mostly unresponsive to traditional drug treatments and conjunctive psychological therapies. I can’t say exactly how this drug did it but it did. I FEEL NORMAL (whatever that is) for the first time in my adult life. By feeling normal I have been able to change destructive thought patterns through counseling and SSRI drug treatment. M 30 2 years
7/28/2008
 5  sleep apnea Initial start of prescription, maybe first 2 days, some 'jitteriness' like if you've had too much caffeine. No other side effects. What a life-saver! 200mg when I wake up before I eat and that clears the brain fog, keeps me awake during my night shift work where there is alot of slow down time work. I can't imagine life without this medicine! F 34 2 years
9/23/2008
 5  to combat extreme fatigue I did not experience any ill-effects from taking Provigil. This medication has assisted me in making it through my very busy work day; as a rehabilitative therapist, I am required to physically lift elderly people, assist them when ambulating, and otherwise need to be on the go for a great part of my day working in a rehabilitative subacute-care hospital setting. While I find that this medication is non-addictive, I have found that when I forget to take it, I am inexplicably tired and seem to "drag" through my day; when I get home and and realize that I had forgotten to take my medication, it makes me realize how effective it really is. I have been taking this medication for approximately 1 and 1/2 years. I have not experienced weight gain or weight loss with this product and it does not affect my sleep at all, which is extremely important in people who need a good night's sleep. F 46 2 years
1/16/2010
 4  Chronic Fatigue Syndrome rapid thoughts, stong urine odor, difficult to go to sleep at night This drug is effective. I can think clearly, and it gives me the energy to accomplish tasks. I can focus on what needs to be done and not just lie around all day watching TV, wishing I had the energy to get up and go. I never take it after 12 noon, or it will not wear off in time for me to sleep. I do not take it every day, perhaps three times a week. But I need it everyday, just don't want to become resistant to its effectiveness. F 48 2 years
6/9/2008
 4  ADD The first couple of weeks I had trouble sleeping. I seem to be more prone to sinus problems. More sensitive to caffeine. I had problems at work and read up on ADD and read how so many others have the same problems. Saw a Psychiatrist and asked him about it. He ordered a QEEG and came to the conclusion I had low histamine levels and put me on Provigil. I take 200mg in the morning and 100-200 in the afternoon on workdays depending on how busy I am. I have forgotten it before on numerous occasions, each time I was reminded how well it works. Overall I can't see where I have had any major side effects, I have always been a little sensitive to caffeine and this has increased that a bit but overall so long as I keep that in check and there are no other outside factors keeping me from sleeping no problems. I have also moved on to a new job where I am doing great, I still have to work to stay organized and I make errors but overall my experience has been great. I was diagnosed with ADD at 28. M 30 2 years
6/13/2008
 4  ADD/daytime sleepiness/depression On a dose of 200mg (once in the morning), jittery movement and rushed talking, extreme impatience with people, extremely decreased appetite, insomnia. However on a dose of 50mg in the morning and 50 mg in the afternoon, barely any negative side affects. When I was first prescribed Provigil, I was almost obsessed with it, and its "magic" to make me the person I wanted to be. More productive, and much more energy. But with 200 mg (or more) in the morning, I was constantly agitated, I started to pick fights with people (when I'm not normally like that), and I barely ate any food at all (which I liked, but wasn't healthy). At the time I was also taking Prozac and Wellbutrin XL, but started them a year before the Provigil. In March of last year, I had a drug induced psychosis after taking too much cough medicine. I know the main reason was the cough medicine, but I'm still convinced the excessive amounts of Provigil didn't help. For weeks before my psychosis, I wasn't sleeping or eating...and the addition of more drugs that didn't let me sleep or eat just pushed me over the edge. Today though, I take only 50 mg in the morning and 50 mg in the afternoon. I use it to get basic things done, and it does help me a lot in school wit F 19 2 years
8/14/2008
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 4  for SSRI apathy Provigil does raise your body temperature a little bit so I felt hot sometimes. It also has a tolerance build up that is perceptible. So when you take it at first it is stronger and more effective than if used every day. I think this works but works better if you take a weekend or a few days off here and there. M 53 2 years
3/21/2009
 4  Narcolepsy diagnosis I am not certain...but it seems I get less done in my life...only the absolutes that are recquired! I can only take 200mg's once a day...and I must say it is the best in the morning. I used to fall asleep at work every day...couldn't sit through even the most stimulating seminar without drifting off. I can't even remember why I didn't like taking more, but I didn't. Now I rely on caffeine pills in the afternoon! F 66 2 years
3/30/2005
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 4  fatigue I exercise an hour daily at the Y and yet I am still very tired especially in the afternoon. I take 100 mg. at around 1 and I have energy through the evening. What is important for me, though, is not to take it daily as I did build up a tolerance. I try to take it 2-3 times a week and never 2 days in a row. It really helps prevent fatigue when driving long distances. I am concerned about LONG TERM side effects and I can not find any studies on this topic. F 58 2 years
5/26/2007
 4  narcholepsy via latent sleep study severe ringing in ears, intermittent sharp/needle eye pain, stiff joints, very poor short term memory, zero sex drive, chewing inside mouth, more OCD, severe abdominal issues aggrevated by any fiberous cereals, excessive talking, poor concentration caused by excessive thoughts, dry eyes, smelly urine, alert but spaced, shaky, irritable, the good thing is that it keeps me awake. I quit taking but DR recommended I take until I have second opionion directed by him. EArs and memory shot even when off med for several months. Seems coincidental and permanent. Initial 200 mg for three days and I was spun out. I only take 1/4 pill. DR is amazed low dose works. Feeling depressed and DR added Celexa, makes me feel like a zombie. Quit Celexa. Don't wake up paralyled, quit having horrible REM episodes when falling asleep, have excellent sleep, does not keep me up, caffeine puts me to sleep, M 48 2 years
11/18/2007
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 4  daytime sleepiness I have experienced some of the side effects listed in the other postings, but to a slight and transient degree. Some of these side effects may be due to several other meds I am on, or due to a combination of them, even though interactions are not indicated in the literature. Everyone's physiology and tolerance is different, I guess. The latest side effect, and most irritating to me so far, is tingling/numbness in my feet. I have been on Provigil about 2 years, with doses from 200mg to 400mg per day. Lately, I have been taking 300mg/day in one morning dose. Also, I am told I am a low level diabetic with fasting blood sugar usually around 105. My doc has me on 100mg/day Januvia. When the tingling/numbness began suddenly in my feet, I became worried that the diabetes was progressing, rather suddenly. I am not very regimented in my diet, but I do exercise vigorously(walking hills and lifting weights) at least 4x/week. Anyways, I stopped the Provigil(300mg, 1xday) for 3 days, and the tingling/numbness in my feet stopped. However, my daytime sleepiness, and my irritability and anti-social demeanor(present prior to Provigil) returned very quickly. I took 100mg Provigil this a.m., and my feet are tingling. I am fairly sure I have developed a new(to me) side effect of the Provigil. I am going to call my doc Monday, and ask him if there is an alternative to the Provigil I can try. My family, my friends, and I, li M 53 2 years
11/8/2008
 4  ADD smelly urine, sometimes skin is hypersensitive sometimes it seems like it works well, and other times it seems like I am taking a placebo and has no effects. Headaches occur sporadically, aspirin works on that, seems ridiculously expensive for what it does although the lack of jitteriness is a good thing, I have actually fallen asleep right after taking it sometimes! M 51 2 years
10/12/2005
 4  fatigue none M 56 2 years
12/10/2003
 4  cognition and memory loss none After seizurs found myself with very poor cognition and profound short term memory loss. On taking the medication I found the problem was helped remarkably. M 2 years
7/30/2004
 4  Fatigue from Fibromyalgia/CFS Headache, most days. Weight loss initially. I have been taking Provigil for a couple of years for extreme fatigue/exhaustion from fibromyalgia. It worked best in the first 3 month of taking it. I felt awake but not jittery, very focused, less foggy and less yawning. The only downside are the headaches I get from this drug. They occur 2-3 times per week on a normal week which is unfortunate. However, due to my insane fatigue, I was not willing to give them up. Two years later and it still helps keep me focused, but it seems to wear off within a few hours. I lost about 20 pounds in the first 3 months as well, which was nice. The weight has crept back on unfortunately. Still a good medication if you can tolerate the headaches! F 39 2 years
200 1X day
3/1/2016
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