PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Severe Fatigue anxiety, sweating spells for hours, severe shaking, crying all the time, paranoia, depression, INCREASED fatigue, headache, nausea My doctor prescribed this because I was experiencing severe fatigue related to some medical problems I was having. The first time I took it I felt increased energy, a little on edge, but not bad. Second day and each subsequent day (I only took it 7 days), my side effects got worse and worse. I would lay on the couch for hours shaking and sweating. I was crying ALL the time. I got extremely depressed to the point I was planning my suicide. I was constantly nervous. Luckily I live with my parents (due to my health problems) and my Mom noticed the changes happening to me and got me off of it. By the time I stopped I was almost psychotic. As a side note, I have no history of mental or mood problems, so this was way out of the norm for me. It took two weeks to feel back to normal. Everyone reacts differently to medications, a lot of people love Provigil, it just did not react well with my body. F 31 1 weeks
12/18/2008
 3  Fatigue, Inability to Focus Only been taking it for about a week and a half, but so far I feel somewhat euphoric during the day. First few days I was fine, but after a few days I have short spells of dizziness and nausea. Kind of makes me feel like I'm watching myself from afar - almost dream-like. Noticed elevated hyper-activity when taken along with energy drink or excessive amounts of caffeine. Other than the afore-mentioned side effects, I like this pretty well. I can tell it's not as strong as some of the stimulants I've been on before, and it's a totally different feeling, but I feel that it is helping me to focus a little more during the day. Not sure as of now whether the side effects are outweighing the benefits. Will report back later. F 19 1.5 weeks
7/5/2007
 5  fibromyalgia/fatigue/RA loss of appetite, slight anxiousness, diarrhea I have only taken this medication for 2 weeks so far but I already feel like a new person. This is the best I have felt in over 10 years. I have energy, I am waking up early although I keep forgetting to eat. I have absolutly no appetite! Will see about the weight loss and if this wonderful new feeling wears off. I am taking 200 mgs at 7am and 200 mgs at 11 am F 29 2 weeks
10/12/2005
 5  sleep apnea minor numbness of face/fingers; occasional headaches; minor nausea; urine odor (not too bad); diminished sexual appetite, but not a complete loss. ocassional tingling in torso area (chest) - not sure if its from medicine keeps me awake all day long; if tired, I will remain fatigued, but not necessarily sleepy; works especially well when I get 7-8 hours of sleep (using CPAP). can now read for hours (excellent benefit). M 38 2 weeks
12/30/2005
 5  Chronic Fatigue Syndrome mild headaches, loss of appetite and the strangest craving to smoke cigarettes, occassional strange urine odor This stuff is pretty amazing, i can actually have a normal day rather than fighting just to get through one. It's not what i feel but what i don't feel which is the constant fatigue, without that life has returned to 'normal'. I hope this can be used as a long term solution, the difference is so great I don't know what i'll do if the fatigue returns. F 30 2 weeks
10/26/2007
 5  Fibro, Chronic fatigue. Mild headache, neck stiffness, and jaw clenching. Also digestive discomfort and excess gas. My rheumatologist prescribed a trial prescription of 200mg tablets. I quickly found out that 200mg is too much for me. Unfortunately, I was coming down with a bad cold the first day I tried it, and didn't sleep for 36 hours. I waited about a week until I was feeling better and split the tablets into 100mg doses. Wow! If this is what "normal" healthy people feel like, I regret feeling miserable for most of my adult life. So far this drug has worked great for me. I'm now getting things done and "almost" enjoying life. The mild headaches have gone away after the first few doses, but the tendency to clench my teeth is still there. The digestive discomfort and excess gas didn't start until I was on the medication for several days. I did not take Provigil today - no gas! We will have to see if this will go away with time. Even if I don't take Provigil everyday, I still seem to experience a boost the day I don't use it. Even considering the side affects, Provigil is extrao M 56 2 weeks
8/20/2007
 4  MS fatigue rubbing my tounge against my teeth. Rapid thoughts This is my 2nd being prescribed Provigil. The first time around,I nearly drove my family crazy with my talking and myself crazy trying to keep my rapid toughts to myself. I dont know if the drug has change or if it is becasue I have gained weight but this time I am not having those problems. I take 1/2 a pill every few days and have been doing wonderful on it. I still took a nap yesterday even with taking it, but I am more productive and can actually do stuff with my kids! F 31 2 weeks
4/14/2008
 4  Shift worker I started having hallucinations approximately 6 days after taking this medication. I never had a hallucination before taking this medication. After the second hallucination, I stopped taking the drug. The drug worked well while I was taking it. F 47 2 weeks
7/17/2012
Email
 4  Fatigue w/ joint pain Increased energy, better able to stay "on-task" (can a clean house be considered a side effect?) Slight constant headache that has eased up the longer I take it. Smelly urine. Increased appetite (I WOULD be the ONE person to gain weight on this drug.) Sleep at first was not restful, but it's getting better. I crash from 8ish - 10ish in the evening which may or may not be related to the drug. Provigil has been very helpful for me so far. The only thing I feel from this drug is a lot more motivation. I don't feel jittery or manic. I even still feel sleepy/tired at times but I can work through it. The first few days I felt VERY motivated but that has tapered off a bit. I still feel that it is effective but I have to get plenty of sleep at night. I'm a little fearful that it will not continue to work for me. F 28 2 weeks
10/22/2005
 4  Narcolepsy Intense headaches for the first three days. They were probably more related to the fact that I went off of all caffeine the day after I started. I'm much more groggy waking up now. Amazed. It's the first time in years that I've been able to make it through a day without a nap. I can still feel my "episodes" coming on, but they aren't nearly as intense; there's no need to stop and sleep. I can be productive at home again since I can actually stay awake for 16 hours at a time. I can drive again (Couldn't stay awake long enough for the 1 hour commute). I actually dream at night again. It used to be I only dreamt when I fell asleep during the day (sometimes while driving or in the middle of work) M 26 2 weeks
11/8/2007
 3  Daytime sleepiness due to circadian I thought I had caught the flu the other day, until reading some of these reviews. I have diarhea, no appitite, chills, fever, headache, etc., however those seem to be an initial side effect. That, or I'm just sick. I worked out yesterday and got winded far too easily, and become winded walking up the stairs--but I've read some people reporting bronchial tightening, so again maybe it is the Provigil. I had a lousy headache the other night, and I usually don't get headaches very often. My mouth has been VERY dry, to the point where my lips are all dry and cracked, despite the fact that I drink prodigious amounts of water all day long. This isn't technically a side effect, but I've noticed the medicine is not as effective as it was when I began (2 weeks ago), and it seems to lose its effectiveness by about 3pm, at which point I crash, unrecoverably. I'll talk about this more in the next section. It worked well the first four days. I was taking 100 mg. I felt energetic, confident, productive, at a time of day I am never those things--morning. However, the strength of effect has subsided somewhat, so I think I will increase to a more common dosage (200mg) and will report back then. One thing I clearly noticed is the crash. I am not a morning person . . . hell, I'm not even a day person. I usually don't catch my first wind until 7pm. On the provigil however, I am a much more functional person during the first half of the day, until the crash in the mid-afternoon. At that point, you'd think I hadn't slept in days. That is weird for me, being a night person, and now being totally drained by 5pm. I teach an anatomy course, in the late evening, so this is also problematic for that reason as well. It seems provigil has given me the first half of the day, but taken away the second (and most productive) half. I'm not so sure that trade off is worth it. Perhaps 200mg will st M 32 2 weeks
2/1/2007
 3  CFIDS, Fibro,Lupus,Sleep Disorders First few days uncomfortable chest pressure. Mild shortness of breath. Mild Hyperactivity. Short-term depression. No deep sleep. Burning eyes. Swollen itchy eyes. Loss of appetite. Mild flushed face (butterfly flush from cheeks over nose). To begin with, I have been struggling with severe fatigue lately. The first few days of Provigil, I started with 200mg and had mild discomfort in the chest with a little shortness of breath. I had also experienced the mild hyperness with moderate depression. I decreased the dosage to 100mg and continued to experience the mild hyperness with no deep sleep at all. The depression lifted but was replaced with itchy, watery eyes. Today woke up with a swollen, itchy eye and a mild flush of a butterly shape over my cheeks and nose. I love the extra lift this gave me in the day, but, at the expense of these side effects, I am afraid to take more. F 43 2 weeks
3/31/2008
 3  Idiopathic daytime sleepiness mild hallucinations, loss of sex drive, strongly odored urine, It was great to feel awake again, but it completely wiped out my sex drive. I also had mild hallucinations while on it, for instance forgetting where objects I had just been interacting with were. Mild euphoria too. M 23 2 weeks
2/1/2008
 3  ADD I have experienced sharp chest pains, dizziness, and a fast heart rate that does not go away, I also have a lot of trouble going to sleep at night now. For the most part, I really liked how it worked, I felt it gave me an added focus, especially at school. However, I don't really like all the side effects of this drug (it's different for each person) and I'm being taken off it, because of the rapid heart rate that occurs consistantly (it's supposedly a serious side effect). F 16 2 weeks
12/18/2007
 3  idiopathic hypersomnia-severe The side effects are the problem. I do have Mitral Valve Prolapse but was recommended to try it anyway. I had jitters and anxiety right away that I was told would subside with time. I could deal with that. I then started having pain in between my shoulder blades that has gotten steadily worse. It is a squeezing, pressure pain with some burning at times. I skipped it one day and the pain was better. When I resumed the pain did too. I was also feeling a "weird" sensation in my chest that progressed to pressure sensations by this past Wed. (I had been taking it about 2 weeks). It got bad enough yesterday that I was considering if I needed to go to the ER and have it checked. I am not going to take anymore until I can talk to my Dr. It is a holiday weekend so that will be a couple of days. The sad thing is that when I worked up to 1 and a 1/2 tablets I could tell a significant difference in my fatigue. My Epworth score went from 22 to a 12. Today I am tired again not taking it. F 37 2 weeks
5/27/2007
 2  Fatigue I have been taking 100mg of Provigil for about 2 weeks. During this time, I have been dealing with headaches, nausea and upset stomach. I honestly don't feel this pill is improving my fatigue. In fact, I feel more tired after taking the pill and feel like I need a nap. M 36 2 weeks
7/19/2007
 2  bipolar meds sleepiness/apnea lightheadedness, vertigo, euphoria after ingestion, crash in late afternoon, accelerated hypomania to mania fighting side effects to see if time will alleviate F 53 2 weeks
6/6/2007
 2  HYPERSOMNOLENCE THE FIRST DAY I WAS ON IT I WOULDN'T STOP TALKING AND WAS HYPER BUT THOUGHT GREAT IT BEATS SLEEPING ALL DAY. THEN 2 DAYS LATER IT STARTED GETTING WORSE I HAD HEADACHES,ANXIETY, FEELING LIKE I HAVE NOT SLEPT IN DAYS, MY BODY WAS SO TIRED AND IRRITABLE. I WAS NOT FOCUSING, MOOD SWINGS IT WAS HORABLE I FEEL WORSE NOW THEN BEFORE F 30 2 weeks
6/8/2007
Email
 2  Night Shift Related Fatigue No side effects I have taken Provigil as directed and I feel just as sleepy as I was before. Maybe I'm not taking enough. 200 mg doesn't do much for me unless I take a NoDoz with it. That can't be healthy. M 37 2 weeks
7/15/2005
 2  Chronic Fatigue Extreme tiredness after medication wore off, after about 6 hours. Worked great for the first six hours, then wore off and left me in an even more tired than before state. Lost its potency after 4-5 days in a row. I decided to switch to Ritalin LA. F 20 2 weeks
2/12/2007

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