PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  narcolepsy, EDS, OSA occasional dull headache, some minor increase in anxiety This is a wonder drug. I previously slept anywhere from 12-18 hours per day, and was still constantly sleepy. I was becoming dysfunctional and almost had several car accidents due to sleepiness. From Day One this stuff worked wonderfully - at first I became very euphoric, but that has worn off. I take it on an empty stomach, as taking it with food makes it not absorb as well for me. I typically take it in the morning and wait an hour or hour and a half before eating. This stuff has given me my life back. I can concentrate, think more clearly, drive safely, and cut back on my caffeine use! I am a pre-med student and thanks to Provigil I can get back on track. 200mg per day works just fine. Everything I've read indicates that higher doses are well tolerated, but do not produce additional benefit. It's expensive, and I had to get a pre-authorization - but all the trouble is WELL worth it. F 28 1 months
4/23/2007
 5  Fibromyalgia / Lupus Slight headache the first few days of starting the meds. A bit of a euphoric feeling, although not unreal. I think it was the added energy made feel good. I eat less, which is good for me. I have had fatigue for three years. This drug has saved my life. I have energy again, but not a nervous energy. I want to work, be with my family, begin and complete projects. This is really a revolutionary experience for me. I tried other meds and didn't like the Side Effects. I take 100 mg in the morning around 9 am. This lasts most of the day. I sleep well at night, sleep more soundly than I have in years and wake up ready to go. I also take an nsaid (non-steroid anti-inflammatory) for my muscle pain, but no other drugs. F 54 1 months
4/23/2007
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 5  Fibromyalgia Diarreah, loss or appetite, headache, jaw clenching I have excessive fatigue and this drug is a lifesaver. I canot get the RX filled because I dont have narcolepsy. I am using samples from my Dr. M 22 1 months
7/18/2004
 4  CFS, EDS, extreme fatigue Softened bowels, slight stomach ache -- not much but I am on a low dose Really helps me feel more mentally alert so I can have a social life again but it doesn't change how tired my body is. F 28 1 months
2/3/2007
 4  narcolepsy Had insomnia the first night only. Have some ringing in the ears, but these are trivial annoyances compared to the great change this med has made in my life. I have only been on it a month, and I feel like I am truly awake after 20 years of sleep! I find at 200mg it wears off by 2pm, so I am going to ask my doctor to increase my dosage or let me take another 200mg at noon each day. This medicatiion has truly saved my life. F 49 1 months
3/21/2007
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 4  Idiopathic Hypersomnia None I take 300mg in the morning then 100mg at midday. I am more awake duing the day but in the evening I still crash at 7pm. Somedays I can fall asleep at 11am for a couple of hours then wake up take my second 100mg and then soon after fall asleep again for a couple of hours. M 34 1 months
100mg 4X day
7/19/2011
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 4  sleeping too much - hypersomnia Often unable to get into a deep sleep; less appetite (thankfully). Stimulants aren't for everyone - be careful. My doctor told me to take half the dose but I forgot & took the full dose for 1 week - which made me jittery, and I didn't sleep well. I cut it in half & that helped the next week. But that still seemed too much, so since then, I now take 1/4 the dose (cutting the pill isn't easy), and that seems to be the right amount for me. I have always needed a lot of sleep, but now I am functioning very well on this dosage & very pleased with the results. Provigil may not be for everyone but that is why YOU need to discuss any issues with YOUR MEDICAL DOCTOR. Sometimes it's just a matter of deciding if the benefits outweigh the downsides. I am glad it has worked for me! It hasn't eliminated all the sleepiness ... yawning throughout the afternoon still, but has eliminated the excessive sleeping for me. F 43 1 months
1/26/2010
 4  EDS due to OSA, fatigue due to meds First week some stomach discomfort, headaches but these went away after splitting my dose 100mg 2x day and taking with food. I feel truly functional for the 1st time in years. Each person reacts differently to meds. I've read every pamphlet/website/research study re: Provigil that I could find. There's risks with any meds and I'm willing to take them w/Provigil to get my life back. I log all side effects so that I have a record of how my body is reacting to the med and can discuss w/my Dr. if necessary. I'm very grateful for Provigil. It's worth it. F 39 1 months
5/28/2008
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 4  Idiopathic Hypersomnia Decreased appetite, lost 8 lbs so far and its only be on it a month. Get very weak and shaky if I don't eat for a very long time. Dry mouth. Also, watch out for Caffeine! Provigil really seems to intensify the effects of caffeine. After drinking one cup of coffee I feel like I just drank 8 cups of coffee. Provigil works better if you take it at the same time each day and definitely take it in the morning! This might sound like common sense, but being a college student I have a different kind of schedule. Somedays I have early classes, somedays I don't. And the weekend is a whole other story. But I try my best to try and wake up at the same time everyday and take it. Also, watch out for Caffeine! Provigil really seems to intensify the effects of caffeine. After drinking one cup of coffee I feel like I just drank 8 cups of coffee. F 20 1 months
2/15/2007
 3  narcholepsy Works great when not on to high of a dose. Had heart palpitations and left arm kind of tingled. Seems to increase blood pressure when taking to high of a dose. Feel it gives me sore muscles and joints but can't find any side affects like this with any one else taking the med. I still like the overall results. Want to keep trying to take the med because I like the way it keeps me alert during the day. Just need to find the right dosage. F 49 1 months
10/16/2007
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 3  ADD/Bipolar thick flem, constant yawning, racing thoughts, insomnia if taken more than 3 days, slight headache. M 21 1 months
1/11/2008
 3  Depression Extremely bad headache during the first week, odd urine smell, irritability, strange dreams, wooshing feeling, numbness Side-effects are kind of sucky, but overall benefits are worth taking it. More energy, ability to concentrate, not overeating. Actually, I now get so engrossed in what I'm doing that I forget to stop and eat. M 35 1 months
6/27/2008
 3  Idiopathic Hypersomnia The only side effect that i've experienced is headaches, which seems to be less frequent over time. I started taking Provigil about a month ago. Originally I took 200mg in the morning. Now I take 200 mg in the morning and 100 mg (half a pill) at around 3 each day. One of my main problems was not being able to wake up in the morning, so I set my alarm for 6am and take my provigil and go back to sleep. Waking up has been less difficult. I still don't feel wonderful, and often get tired. At night I become EXTREMELY talkative. It's almost embarassing that I can't shut myself up. I'll report back after I've taken it for a few months F 19 1 months
2/24/2009
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 3  depression, sleepiness mild headache first few days, intensified depression The main reason my doctor prescribed Provigil was that I have extreme morning sleepiness and lack of energy. I've been on Cymbalta for over 2 years, but at the dose I tolerate best it doesn't completely relieve the depression. I started Provigil at 1/3 of a 200 mg tablet (approx. 67 mg) for 10 days, and then increased to 1/2 (100 mg) per doctor's instructions. The first two or three days on Provigil I did have increased energy and motivation, and although that faded somewhat after a week or so I did feel more alert. Some nights I had a lot of trouble getting to sleep, and my sleep schedule became erratic because I would stay up very late until I became sleepy. Earlier this week, after having taken Provigil for about 1 month, I became extremely depressed, anxious, and tearful. I didn't link it to Provigil until I read the comments of others who have had a similar experience. I had also noticed that I was talking a lot, which is out of character for me, but I didn't link that to the Provigil, either, until I read other patients' comments. My doctor has taken me off Provigil and increased the Cymbalta. I may try it again at a low dose because I need some relief from the sleepiness/fatigue, which has returned full force. F 54 1 months
5/2/2009
 3  Fatigue, Possible Sleep Apnea RASH, loss of appetite, mania, over-medicated feeling, acne, thinning hair Like many others, the first time I took it was great! I had energy, hyper mental clarity, and a feeling of extreme confidence. After a couple of weeks it wasn't working as well, and then the side effects kicked in. I felt sweaty, it seemed like my heart was racing (I have high BP), and the worst was the late afternoon crash I would experience everyday at 3 pm; I would be so drained I could barely finish my work day, which defeated the entire purpose of taking the medication. I also had a terrible rash on my face (my eye almost swelled shut), neck, and arms. At the time I blamed the rash on possible poison ivy since I had weeded the lawn, but now I'm not so sure. My face was also breaking out severely, and I had alway had a beautiful complexion. I stopped taking it when I ran out after 30 days. In about another month I re-filled it, wanting to give it another try since it did help initially, and I had lost weight as a bonus. This time it worked for only a day or 2 before the negative outweighed the positive effects, not to mention the $50 co-pay. I'm convinced that if a drug is not absolutely necessary to sustain your life, it's not worth taking due to the cost and inevitable unpleasant or even harmful side effects. F 44 1 months
7/24/2009
 3  sleep apnea, grad school This medication is very peculiar. I think diet affects it, because the side effects and overall efficiency change from day to day for me. I am definitely more alert, and when I "crash" at night, I fall asleep much more quickly. However, I feel more anxious and slightly depressed using this medication. Also, if I am very stressed (say, having a big paper due), the anxious side effects are hightened to the point I am physically shaking. On the whole, I am happy with the medication, I just dislike the frequency of the side effects. F 33 1 months
200mg
12/9/2014
 3  excessive daytime sleepiness intense gastrointestinal discomfort including diarrhea and bloating I've tried taking it with food but it really doesn't help. Also, I discovered that even after taking the drug and waiting 3 or more hours, coffee is a no-go and makes the aforementioned issues so much worse. Bummer for me because I love coffee. F 48 1 months
200 mg 1X day
10/19/2020
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 2  For idiopathic hypersomnia Blurred vision Worthless, did nothing for my symptoms, no energy, continued brain fog, still got sleepy thru the day, no concentration , trouble remembering things , continued to have sleep drunkeness. Could take my dosage of 100mg twice a day and sleep 13 hours get up, non rested, and have to take a nap within couple hours. Nap would be couple hours long. Not the wonder drug for me. Was on adderal 30 mg once a day felt normal no buzz effect, but developed tachycardia so my doctor tried this . Now we have to look for something else to try. F 54 1 months
200 MG
3/28/2016
 2  To counteract the drowsiness None. It was like a placebo This drug may have well been a pill filled with flour. It did NOTHING for me. I still slept all the time and was constantly exhausted. It did not keep me awake whatsoever. Everyone praises this drug, but I don't get it, it didn't work for me. M 23 1 months
9/3/2008
 2  excessive sleepiness sleepiness! terrible indigestion Worked great for first few weeks but have now developed almost intolerable feeling of fullness in upper abdomen a few hours after taking it, and sleepiness has returned but much worse. F 42 1 months
10/19/2006

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