PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Exams / depression / work Took for exams. Concentration excellent the first 4 days straight on it. Excellent mood, nothing could irritate me. In my own focused world. "Life is great" followed by moments of INTENSE CREATIVITY/INSPIRATION. but: wheezing / lung fluid / chest pain / my eyes were "slow." DAY 5: withdrew to get sleep, unable to. Extreme fatigue, social phobia, depression. ( continue for 2 weeks when I stopped it.) F 20 2 months
200 2X day
6/27/2010
 4  narcolepsy some headaches, i became very irritable F 22 2 months
8/4/2001
 4  Narcolepsy Nausea, light-headedness, scattered thoughts, inability to concentrate on one project for more than about 20 minutes without a "break"...but not picking it back up when I'm "rested" because I completely forget what I was doing. I get really moody, though and I have cought myself chewing my bottom lip off (literally layer by layer until it's bleeding), grinding my teeth, I'm WAY more talkative than I used to be. I guess it has it's good points and its bad because even though I'm stoked about being able to live through my day without wondering who I'm going to fall asleep in front of...I really could care less. Well, I don't fall asleep driving down the highway anymore. :) Or at the stoplights. OR in the doctor's office. OR at my desk at work. OR as soon as i walk through the door at home...especially if it's quiet. I would guess i could say it gave me part of my life back. But, even with that, if I slept through it I wouldn't know to care...but this is forcing me to "not" care because my body/brain won't allow me to care enough to process whatever it is I am allowed an opinion on. Then I have crazy stupid dreams...other than that, I suppose it's okay. F 29 2 months
12/27/2006
 3  Sleepiness None to speak of, but tolerance is building up. 100mg was enough to help le stay awake from 7 a.m. to 8 p.m., now I fell sleepy much earlier (early afternoon). M 46 2 months
4/9/2006
 3  Depression lack of energy none M 33 2 months
3/15/2001
 3  narcolespy I've been on Provigil for about 2 months 600 mg. I have been experiencing ringing in one ear for about a month. Not sure if this is associated with the provigil, but did not notice this before taking the drug. My doctor started me off with 200 mg for 3 days; then went to 400 mg for additional 3 days, finally 600 mg daily. The medication seems to work better than Retalin for me,(15 mg 3xday) however, I find that I still get very lethargic after about 4 or 5 hours, if that long. Yawning is presistent. My eyes become droopy (have been asked by others if I'm ok) I'm not necessarily sleepy, but lethargic. Concerned that I'm taking such a high doseage and experiencing these issues. Has anyone else reported ringing in the ears? F 54 2 months
11/28/2005
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 3  Fatigue/Daytime sleepiness 100 mg no side effects/did not work 200 mg no side effects/did not work Just started 400 mg, its been 4 days of living in a fog with mild headaches. I can't seem to focus on the task at hand. I'm not tired anymore during the day, but I have to be focused at work. Has anyone else have problems like this starting out? Feed back greatly appreciated. M 39 2 months
3/20/2008
Email
 3  chronic pain & med narcolepsy dry mouth, headaches, strange smelling/dark coloured urine, clinch jaw, magnified pain,severe abdominal pain. All side effects are slowly reduced or gone. Chronic pain & medication induced narcolepsy 3 yrs. First 2 days great! 3rd day only helped keep on task and clearer mind. I take 100 first thing, 100 late morning. Dr said this was the max. I printed some responses from this site for him to read to challange him on that. Maybe with an increase dosage provigil will work for me. F 45 2 months
4/1/2008
 3  excessive sleepiness Nausea, Headaches, Increased Heart Rate, Afternoon Crash, Impaired Depth Perception Provigil works - started taking it 2 months ago on occasion and it managed to get me out of bed before 8 am, which is great. Unfortunately it comes hand-in-hand with headaches, severe nausea (most times I would wake up to throw up and continue throwing up throughout the morning) and while it's designed to make you focus, I find the associated side effects render me less productive. There is a definite afternoon crash (circa 3pm on a regular 8 to 5 day), which doesn't make me sleepy - just distracted and dizzy. 50% of the times I've taken it, I experience insomnia and can't fall asleep until +/- 3 am. Friendly suggestion: this is a relatively new drug and most of its side effects are still getting added to the list...If you don't absolutely have to take it - don't. M 27 2 months
9/2/2009
 3  Narcolepsy w/Cataplexy Started taking Modafinil 2 months ago after 2 years of taking Dextroamphetamine. Stopped Dextroamphetamine due to increased tolerance, decreased effectivenes, hard to get prescription filled and just wanted to give my body a break...I felt like I was on "over-drive". Since taking Modafinil my ability to concentrate has increased, analyticsl skills improved dramatically and mood is happy. I also like that there is no big "speedy high" and no overheating or sweating too much unlike Dextroamphetamines. Downside to Modafinil is that my productivity has decreased, awake time & energy is decreased, social life decreased and I obsess and overanalyze things way too much. Great if I want to be a professional recluse analyzing data all day but my career and life require me to be more social & awake. Will be asking to change back to Dextro soon. F 39 2 months
200mg 1x
5/28/2014
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 3  Difficulting getting up feelings of physical tension I have insomnia and sleep apnea. Even with a CPAP and doses of Trazodone, Seroquil and klonopin, I still have difficulties going to sleep. I find it hard to get up as a result oif the meds I need to get to sleep and stay asleep. I take 100 mg of Provigil to try and become awake earlier. The doctors keep playing with the dosage and the dosages of my sleep meds to try and get a balance, but haven't found one yet. M 61 2 months
2/28/2009
 2  narcolepsy dry mouth, constant headaches, jaw clinching, foul smelling urine The first day I took this drug I was so excited because of the energy I felt. The next morning when I woke, took my medication with no reaction. Up the dosage and had the same result. Great energy the first day, then no increase in energy. The positive side though was how I had more clarity in my thinking. Even though I didn't have energy back I was willing to stay on the drug to keep the fog out of my brain. I was hopeful the side effects would eventually go away. Instead they got worse. I stopped taking the drug two days ago and I am really glad. It's nice not to wake up with a headache after clinching my teeth all night. Good luck to those who are having success and happy hunting to those of us that are still searching. F 45 2 months
4/18/2008
 2  Magor depression I have developed a metal taste on my tounge and numbness in different parts of my body and the slight vertigo has turned into a disaster and I feel like I have lost touch with reality, awareness, focusing and could be more..?? M 70 2 months
200 mg ×2
6/3/2016
Email
 1  Stroke related sleep apnea Hallucinations, extreme sleeplessness, restless, overactive imagination This was prescribed for my aged father after a stroke - to "pump him up" for rehab, etc. This med caused hallucinations, repeatedly, and caused him to lose sleep and his imaginaton was "out of this world." As we began to wean him off this med, he could not sleep at all, for days on end. After the med was out of his system, the hallucinations and restless subsided or went away completely. M 77 2 months
5/23/2008
 1  schizoaffective (tired from meds) hypnopompic hallucinations that continued for at least a year after stopping meds. i would wake up in the middle of the night and basically still be dreaming but awake. i would see giant spiders over my bed and freak out. this faded gradually, but not for like a year after discontinuing the med. did nothing good for me, but gave me terrifying hallucinations that woke me up alomst every night screaming. so bad that my neighbors complained. horrifying. and it didn't go away til like a year after i stopped. F 24 2 months
7/21/2007
 1  Narcolepsy Good side effects: More talkative (especially good for me given my problems with extreme shyness), Think more clearly (if experiencing exhaustion-induced brainfog), Increased creativity, Mild euphoria, ---Neutral side effects: Strange smell of urine, Altered sense of taste, Greatly increased thirst, Increased urination, Nausea, Increased heart rate, --Bad side effects: Sore, red eyes, Headache on sides of head, Strong "gut feeling" that I didn't want to take the 2nd dose (back when I first started taking it, I was following the label for dosing twice daily), Delayed sleep if I took the second dose, Occasional distorted thoughts, Increased sound sensitivity, Chest pain, Inability to concentrate on specific tasks, --Really bad side effects: Numbness in center of forehead, Feeling very sick and exhausted for a whole week after stopping previously, Strange, unnatural feelings, Feeling horrible if I allowed myself to nap while on Provigil Crashing a Let me just say that when I started taking it, the first week was Great. But after that, I took it on-and-off, and the effects were increasingly inconsistent. Sometimes it worked, and worked very well, other times I would be in a stupor for the entire day, even with the medicine. Days when my thoughts were completely distorted became more common, and there were weekends when I would be essentially crashed the entire time but I attributed it to the sleep disruptions at night. The side effects got worse through this time. Last night, I had another horrible crash. I started feeling horribly exhausted at around 10:00, and went to bed. I slept for one hour or less before waking up, feeling the most extreme version of a nightly crash that I had ever felt... except that I wasn't sleepy. The headache, the numbmess, the weirdness, hyper-sensitivity to the environment noise, all of the negative side effects were there... and I was wide awake. Not just awake, but WIRED. I had a completely te M 27 2 months
8/16/2008
 1  chronic fatigue Minor Rash on the forearms, extreme headaches I took the generic brand Modalert. I found it to be generally ineffective when taken by mouth. Taken in the morning I would develop severe headaches later in the day. Eventually I progressed to snorting 100mg of the drug at night time. Snorting the drug was the only way to experience its effects for me. This improved my problem with fatigue and allowed me to get more done after work, It did not keep me up at night. Until I got a rash on my arm. A common side effect of Modafinil is skin rash, which can lead to Steven Johnsons Syndrome. Your skin starts to peel off until you look like a burn victim. Fortunately this is a rare occurrence, and now that I have gotten my first rash I have decided to stop taking it. I would say that this drug is too dangerous to mess with. Unless you really have narcolepsy like Mr. Bean in the movie Rat Race. If you're just feeling tired, drink coffee instead. It's better to be tired than have your skin melt off your face and go blind. Again, SJS is a rare occurrence, but you have a much better chance of getting it by taking drugs you don't need. M 25 2 months
100mg 1X day
9/7/2010
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 5  autoimmune dysfunction+ bad fatigue possible aggitation of existing head/neck ache on left side. urine smells different or strong when i do not keep well hydrated. i feel a little queasy sometimes, but nothing serious... initially jittery, (200 mg, so backed down to 100 mg)after 2 months, seems to level off. tried 200 mg today and feel fine, maybe a little "brighter". provigil has made a very positive impact on my life. i lost my health insurance due to this NIGHTMARE quagmire of autoimmune disease/dyfunctions, which is still in the process of being firmly diagnosed, (undifferentiated connective tissue disease, sjogrens, endocrine and central nervous system/ possible cardiac involvement, and God knows what else. i have varied and less typical symptoms) provigil is newer, expensive and basically clinically approved for narcolepsy only, so i am seeking patient assistance from NORD,(national assn. for rare disorders via cephalon; 203-744-0100) my rheumatologist initially prescribed it for me and i cannot afford it on my own. i am in the professional fitness industry, so the changes seen/symptoms felt in my body are quite visable to me more so than to health professionals that don't i don't look sick to them by comparison to other people in similar situations is what i keep hearing although pr.ovigil does not help with the chronic pain related to my c F 45 2.5 months
9/20/2005
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 4  lupus didnt see affect for a few days, doesnt work as well as I had hoped. Most days it keeps me awake though. Side effects included, sudden severe mood swings (passed very quickly), excessive sweating, anxiousness, lack of concentration, overwhelming need for interpersonal contact/talking, teeth grinding, jitters. has similar side effects as a dose of adderal, just not as strong F 19 2.5 months
12/11/2006
 5  Daytime drowsiness Strong urine odor; some anxiety. But it works so well, and has improved my life so much, the benefits far outweigh the negative side effects. The anxiety actually helps me make the day so much more productive. I only take it when I know I will be sitting in long and boring meetings, or when I know I have to keep especially alert while working on a project that involves a lot of reading. 200 mg seems to do it, sometimes 400 is needed. For me, I have to classify it as a "miracle drug." M 62 3 months
6/18/2006

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