PROVIGIL Reviews (MODAFINIL)

Average Rating: 3.6 (619 Ratings)

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 CNS, MISCELLANEOUS    DEA Schedule IV   

 Type: Rx Drug

  

PROVIGIL  (MODAFINIL):  Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep (obstructive sleep apnea). It is also used to help you stay awake during work hours if you have a work schedule that keeps you from having a normal sleep routine (shift work sleep disorder). This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil does not take the place of getting enough sleep. It should not be used to treat tiredness or hold off sleep in people who do not have a sleep disorder. It is not known how modafinil works to keep you awake. It is thought to work by affecting certain substances in the brain that control the sleep/wake cycle.   FDA Approval Date: 1998-12-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROVIGIL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROVIGILCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  no energy & could not get out of th Headaches, racing heartbeat & stomachs upset with bad constipation & intense abdomen cramps. F 71 10 months
10/3/2014
 3  cronic fatigue-major depression im on another medication so its hard to seperate some side effects. The ones i can narrow down to this medication are; strong medicine smell in urine, major crash towards the end of the medication cycle. a very small weight gain, but i havent confirmed if it is a direct cause of the provigil or not. I was on adderall which was great, but would give me a stumach ache for a short time after each dose, and bad night sweats. We think it even messed with my blood levels. Without it though, i was at 0 function. After more then a year i was changed to provigil to see if it would be any better. It helpes me start my day..which was a god send. I do feel now, that i need to take a higher dose to get enough of an effect. Im going to be talkig to my doctor about that. Maybe I just need a higher dose, or maybe Im building up a tolerance. F 30 10 months
7/30/2006
 1  narcolepsy My thinking was all screwed up - had mood swings - couldn't focus on anything. One minute I would be fine the next I was argumentative. Little things that would have never bothered me before became major issues. It almost destroyed my marriage - I would act inappropriately and had horrible mood swings. My family could see what it was doing to me and got me off this horrilbe stuff. I would have to say they probably saved my life and my marriage. DO NOT TAKE THIS HORRIBLE STUFF!!! M 26 10 months
10/10/2009
 5  Sleep Apnea occasional headaches, strong-smelling urine, slight anxiety, disrupts sleep schedule if taken too late, suppressed appetite (lost 20 pounds in the first 2 months of being on Provigil--but I needed to lose the weight), loose/soft stool This truly is an amazing drug. I'm taking 400mg every day; 200mg in the morning and 200mg in the afternoon. I'm currently using CPAP for "obstructive" sleep apnea, though my ENT doctor was unable to identify any obstruction, but I'm in the process of investigating thyroid issues potentially caused by a pituitary tumor--which may actually be causing my sleep apnea. In any event, CPAP isn't working too well for me, and I suffer from excessive daytime sleepiness, compounded by my recent thyroid problems, which make me feel more tired, as if this were even possible. Provigil's side effects were very noticeable for me at first, then became much milder after the first week or two. I'm able to stay awake and alert more easily during the day whereas I used to fall asleep in every single class during college (recent grad) and perform extremely poorly in classes early/late in the day. I wish I had started Provigil much earlier, because I've been exhausted my entire life, to the point w F 22 11 months
7/23/2008
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 3  Sleep Apnea less drowsy M 11 months
2/5/2007
 5  fatigue from LUPUS Mild anxiety when active, or after 12 hr shift/200mg Headache, palpatations. Has given me my life back. Now able to do what I love as ER RN, be active with my son and husband when needed. Can go days without taking it - when I do take it I feel positive, not quite euphoric, but just happy and alive. Have had depression for years and this is the best drug I have ever taken without risk of addiction or side effects. I love it. F 50 12 months
11/14/2006
 4  Chronic Fatigue/Fibromyalgia Difficulty Concentrating, Stomache Pain, Insomnia, Moodiness. Worked great first six months. Now after 1 year Provigil seems to have lost it's effectiveness. Increased dosage from 200mg daily to 400mg daily produced tiredness and a feeling of being unwell and moody along with muscle aches and bloating. First six months of treatment gave me my life back. Past six months not so good. Will discontinue taking Provigil for a time and most likely try again in a few months. No withdrawal with this medication. The cost of this medication is very high. Most insurance will not cover unless prescribed for narcolepsy or ADD. F 48 12 months
7/7/2006
 5  Depression/Rotating Shifts Suppression of appetite, jittery/shaky at first (went away after a few days), could focus and get stuff done! Headaches at first, went away with time. My psych HATES caffeine and I'm a serious caffeine junkie. Prescribed me this when I mentioned how first thing I do in the AM is turn on the coffee pot. Noticed effects IMMEDIATELY...like within an hour after taking. I've had days where I've cleaned the apartment and then some after taking my morning dose. However, effect seems to wear off and tolerance has increased over time and a years'-plus use. Has helped at times pull me out of mild depressive spells. Terribly expensive, my MD had to give prior authorization before insurance would cover it. HORRIBLE fatigue if I take it for awhile then stop or forget to refill it. But overall, satisfied. Except for the loss of appetite, bc I'm a little guy. M 28 16 months
400 2X day
10/18/2011
 1  narcolepsy change in personality, mood swings, doing things out of character and lying about it This drug nearly ruined my life! I had and huge change in personality, I would have mood swings. I did things that were out of character for me and then I would lie about it. I was working two jobs and was constantly tired and was diagnosed with narcolepsy because I could not stay awake - well duh! I now take a nap in the afternoon and try to get more sleep at night - I am now off this awful stuff and living a very happy and content life! DON'T GET ON THIS STUFF IT WILL RUIN YOUR LIFE!!! M 26 16 months
1/7/2010
 5  multiple schlerosis weight loss I started taking 100 mg of Provigil a year and a half ago. I am now up to 200 mg one time a day and I take it around 11am. My concern is my weight. I was 183 pounds, I am now 132 pounds. I have also mad dietary changes that includes a lot less carbs. Potatoes and breads to name a few. Not that they are 100% out of my diet, maybe 75% from my diet. People are starting to look at me as if I am not doing the right thing. I love that I have so much more energy to feel normal. F 39 18 months
7/5/2008
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 5  Narcolepsy The first day, I took 200mg and was amazed how alert I was. However, that night I had trouble falling asleep. I cut the dosage in half and slept fine the next night. After a month, I returned to 200mg and have had no side effects for 2 years. I have always been against taking medication, especially when it affects my brain. However, my college roommates called me "the sleeper" and I lost an opportunity at a prestigious consulting firm because as an intern I fell asleep in meetings. I then began my career in a traveling sales role so that I would not be behind a desk. I do not drink alcohal, yet my coworkers often asked if I was hung-over. At my next job, I was told to get more sleep or I would be fired. Getting enough sleep was not my problem. Doctor ran several tests and sent me toa sleep lab, but found nothing wrong. Thinking I might have a mild case of narcolepsy, they suggested I try Provigil for a week. From that day forward, I've had my life back. At first, 200mg a day was too much, so I dropped to 100mg a day. After a month, I began taking 200mg again. For the last two years I have been able to work a full day without getting drowsy. I have returned to an office job and am always alert and focused. I think M 30 24 months
3/5/2008
 5  Fatigue due to MS Inability to sleep if taken too late in the day. After needing to change MS medications, was faced with life altering fatigue. This medication had done wonders for my quality of life. Highly recommend. M 46 24 months
100mg 1X day
6/17/2015
 5  To counter side effects of Cymbalta I take the maximum dosage,200 mg tablets X 2 daily. Only one, and I didn't realize it might be a side effect until I read other entries on this site: the VERY occasional front lobe headache that quickly goes away with asparin. The drug I have to take, Cymbalta, leaves me overwhelmingly sleepy. I literally couldn't function w/out Proviil. Recently, the Thurs. before the MLK birthday long weekend. I ran out and, through a snafu, couldn't refill untl Tues. I slept, off and on, both day and night, through the long weekend. M 63 86 months
1/25/2009
 5  sleeping too much maybe a little high but nothing else M 57 1 years
1/1/2009
 5  Sedation/Parkinsons Medication None Best medication I've taken for Parkinson's! I felt almost "normal" while using it. My energy level was back to normal, I was clear headed, able to think clearer, and the ability to function normally was fantastic. I also required less Parkiinson's medication. I highly recommend it's use for patients with Parkinson's. F 58 1 years
9/3/2009
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 5  chronic fatigue overeating discontinued, lost all excess weight, depression lifted, calmness prevails, focused, alert, desire to learn somehow this works better than any antidepressants I have been prescribed (a true lifer) for major depressive disorder. see my psychiatrist regularly. currently not taking any more antidepressants which cause too much lethargy. just taking provigil 200 mg with coffee before work and good to go for all day. normal human being finally after 40 years of chronic fatigue. F 55 1 years
7/24/2009
 5  PTSD, Depression, Sleepiness None whatsoever, which is unusual for me. I have severe PTSD with major depression/difficulty sleeping. I tried many anti-depressants and all were in-effective and/or worsened my condition. I decided to focus on talk therapy and nutritional support but sleep loss due to nightmares, low energy, and afternoon sleepiness limited my progress. After research I tried Provigil. I take 100mg upon waking and have improved energy, focus, mood, and mental clarity. Despite suspicions I have found no side effects. I skip taking Provigil periodically to check for dependence and see none. The greatest benefit is that it aids in keeping me in a frame of mind where I can put forth the maximum effort in therapy while at the same time deal with everyday issues. I want to be the best husband and step-father I can be and Provigil has proven to be an important addition to the other steps I take to achieve my goals. I'm still squeamish about relying on a pill and would rather not, but I have a lot of work to do to improve who I am and the Pr M 51 1 years
3/26/2008
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 5  Chronic Fatigue Syndrome/Narcolepsy Headaches. Absolutely, positively MUST start with a low dose. IF you have a headache -- your dose is too high -- reduce your dose for awhile. With time, I was able to increase my dosage. F 55 1 years
4/29/2008
 5  Fatigue and cog problems from MS The first few weeks I noticed a real buzz. High anxiety and hyper active. It was the most energy I'd felt in years. After the buzz wore off, my life became normal, wich was a great improvement over the constant feelings of lethargy and helplessness I used to feel. This drug has returned my pre-MS life to me. I can fully function on the job where I had felt (just weeks earlier) that I could not go on any further. It also improved my sleepless nights. I am at high energy (busy and accomplishing things) all day, so I welcome sleep when the time came. 200mg every morning keeps this wake/sleep cycle in balance. Provigil gave me back my life. M 54 1 years
2/6/2005
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 5  Restless leg syndrome, sleepiness headaches 1st few weeks; wake earlier than normal, but still feel refreshed; more vivid dreams; slight anxiety at 200mg, but fine with 100mg/day I was diagnosed with Restless Legs Syndrome, which remains untreated because I can't tolerate the meds (made me compulsive/manic). I am a computer programmer and almost lost my job because I could not stay awake in the afternoons and could not focus at all. I was so tired in the evenings that just making dinner for my family was a huge effort. Provigil allows me to function normally, do my job well, and still get a decent night's sleep. I wake up earlier than normal, but I seem to need less sleep. I used to sleep 9 hours and still feel tired -- now I get by fine on 7 or 8. An occasional headache was the only annoying side effect, but I rarely get those now. I took the prescribed 200mg for a day or two, but it made me anxious so I cut back to 1/2 pill and it works great. On weekends I skip it altogether. My advice is to start at a lower dose and work up to what works for you. If you have a serious reaction or are on a million other drugs, then maybe its not for you, but it did save my job, and my family is deeply grateful that I'm back to my upbeat, energetic self. F 45 1 years
100mg 1X day
2/20/2010

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