MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  RLS NO SIDE EFFECTS. It is absolutely wonderful to get a good nights sleep without having an attack of RLS. I can now go on trips without worrying if I was going to disturb others in the house with me walking the floors. It is a new lease on life for me. F 56 3 days
11/1/2006
 5  MS induced RLS I am not aware of any side effects. Very surprized reading all the bad reactions - I guess I am VERY lucky. Mirapex has been a godsend for me. I don't think I could function without it. Started 5 yrs ago taking as needed but now increased to daily. Of all the meds I take, I think Mirapex would be the last one I would give up. F 60 5 years
0.50 mg 1X day
11/13/2012
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 5  RLS After four years of taking the medication, I have just ow began to experience Nausea with a very high dose. Other than that, I can not say that I have experienced any other side effects that I know of. One piece of advice, never, ever take Benadryl or Phenergan without taking Mirapex if you have RLS. Both of these medications can increase RLS s/s to the most severe degree... This medication has changed my life. I began having very severe RLS s/s when I was in college. could not date, go to movies, or anything that was associated with night time activities. I worked as a night shift nurse for a few years to try to stem off the terrible feelings by moving around all night long. My doctor finally prescribed Sinemet and it worked for about 6 months and then augmented the symptoms of RLS to my arms as well as my legs. I was worse than ever. I tried Requip and had a very weird reaction to it called a dystonic reaction....Then they tried me on Mirapex. Now I can not live without it. I can sleep and if I forget the drug I am miserable. I don't mind the nausea at all, it is nothing compared to the misery of RLS. F 29 5 years
10/15/2006
 5  RLS Some nervousness, gas, weight gain. I used to consider myself lucky if I got 2 or more hours of sleep a night. I would be dragging myself around all day and sleep all weekend to catch up. I started the mirapex 3 months ago and now can sleep 6 or more hours a night. not quite perfect but I'll take it. The twitches in my legs are pretty much gone, but I do feel nervous and anxious when I try to sleep and that does keep me up a little. F 27 3 months
10/19/2006
 5  Restless Legs Severe nausea in the morning after taking the drug, combined with anxiety. I decreased the amount to .125, which works fine. The drug is well named--it has been a miracle for me. I sleep all night and wake up alive, for the first time. So far, I've even quit grinding my teeth. I've had RLS all my life, before I could describe it and well before it had a name. For most of my life, doctors just looked at me funny when I tried to tell them how agonizing it was; finally I quit trying to tell them. If this drug ever goes off the market, I will be one of those pathetic characters trying to score it on the street. F 65 6 months
9/12/2006
 5  RLS None Amazing! I've had RLS since I was a teenager and normally suffer with restless legs nightly, but since I've been taking Mirapex, I haven't had one episode! F 44 14 days
9/20/2006
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 5  Sleep Behavior Disorder Possible weight gain.....I take a lot of other meds also:-( Has really helped, along with klonipin, to keep me from acting out my dreams. Consequently I now get a good nights sleep. F 52 5 months
1/28/2010
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 5  RLS No side effects that are apparent to me. If I do not take mirapex exactly at the same time each night, my restless legs will begin and I am reminded how intolerable the syndrome is to my quality of life. I too, was diagnosed with RLS, before it was widely accepted by doctors. It was a neurologist who prescribed it for me and I cannot imagine what life would be like without this drug. I am concerned about compulsivensss but I honestly can say that I loved shopping as much before mirapex as I do now. F 55 15 years
1.5 MG 1X day
6/6/2010
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 5  restless legs Never had a problem or a side effect Wonderful - wouldn't be without it. F 49 6 years
.10 mg 2X day
6/8/2010
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 5  RLS and Fibro none has worked great! F 51 2 years
0.25 1X day
8/2/2010
 5  Fibromyalgia, Parkinson's Some weight gain (5-8 lbs) that seems to have stopped since I no longer want to eat too often, Some excess sex drive and romantic inclinations that are annoying, Some sleep problems at night and drowsiness in afternoon. First med that I have tried (out of many over the past 10 years) that actually took away the fibromyalgia pain. It fixed moderate bradykinesia and stiffness. It seems to have helped flagging memory and cognition to some degree. It also seems to have enhanced stress tolerance and boosted low self-confidence. I think it is important to not take too high of a dose - increment and wait until your system has adapted to current dose before incrementing again. Avoid eating protein within an hour of taking the pill. F 38 60 days
0.25 2X day
9/30/2010
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 5  treatment resistant depression none went off of Mirapex for just a few days (to try a different yet conflicting med), extreme suicidal thoughts and was ready to self-admitt to be hospitalized. Went back on, was fine. F 33 2 years
0.75 3X day
11/10/2010
 5  Restless Leg Syndrome slight morning headache at first; none now drowsiness This drug was an excellent fit for my situation. The sleep study results indicated 'involuntary periodic limb movements' and I exhibited the symptoms of RLS over the years. My sleep was disrupted and not restful. Now, I sleep through the night and am very comfortable. I take one .5 about three hours before bed. It is possible that .75 might be needed when I go in for my 90 day follow-up with my primary care physician-I still have some symptoms during the afternoon but counter that by doing some physical labor--weed, clean the pool, vacuum. I have a lot of energy! F 56 2 months
.5 mg 1X day
2/14/2011
 5  RLS None that I'm aware of - I was taking Permex previously. My Mother, Sister, and Daughter also have severe RLS and take Merapex- with no apparent side effects. It has been a "lifesaver" for us. F 68 10 years
50 mg 2X day
7/20/2011
 5  RLS Initially some drowsiness. Some obsession with a particular relationship and increased sex drive while taking bioidentical hormones also, for first two years. Recently some fibro type stuff. But all these could have other explanations or have appeared anyway. Overall a life saver the last five years. Previously had RLS for 35 years, had gotten to be nightly two hour sessions. I started on half a min. dose: .125 mg once a day at dusk, and that worked (unless I forgot) for 4 years. Then, along with some stressful life events, RLS would break through some and I increased it to .2 mg. Now I think I better up it some more, a year later. F 61 5 years
.125 mg 1X day
8/17/2011
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 5  RLS This drug has saved my life. I could not sleep without it. I have had no side effects from taking Mirapex. I have had no side effects at all with Mirapex. It truly has been a "Miracle" pill for me. I have been taking it for 2 years. F 64 2 years
0.5 1X day
5/28/2011
Email
 5  RLS Possible memory impairment. I don't care. Mirapex is a miracle for me. No obsessive/compulsive behaviors, narcolepsy, nausea, etc. I can SLEEP! My RLS is so awful that my legs jump by themselves if I don't move them proactively. It's unbearable torture. I'd rather be in pain. Thank you Mirapex! F 51 1 years
0.25 mg x2 1X day
4/29/2012
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 5  for rls Requip gave me severe nausea. I have had no side effects from Mirapex. F 60 1 months
o.50 mg
8/30/2015
 5  Restless leg syndrome. Headaches sometimes. I am so greatful for Mirapex! It has made such a difference in my life. F 57 3 years
.25 mg
3/20/2016
 5  RLS Originally it made me somewhat nauseous and dopey. I stopped it, went back on Requip, quit that, and tried Mirapex again. Never had a problem after that. I was originally prescribed Requip for RLS, but found that it stopped working after a relatively brief period of time. Switched over to Mirapex and never looked back. Works like a charm. An added benefit is that is makes me drowsy. I take before bed so that's perfect. F 58 5 years
.50 1X day
12/21/2014

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