MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  RLS Relieved the RLS but started making me jittery at night, as if I'd had an entire pot of coffee before bed. Also had "hot flashes" during the day. Interfered with my sleep worse than the RLS did. For about a day it was ideal between relief from RLS and any of the side effects but after the third day of the higher dose in the sample pack I had to stop. Starter dose didn't do anything. Will be trying Requip next. If the side effects weren't so bad, I'd stay on it but the main reason I need the relief is the RLS interfering with sleep. Daytime RLS symptoms are tolerable for now. M 44 7 days
9/16/2008
 2  rls Took .125 pill first night. What had previously been aching left calf suddenly all joints in body were impacted. Was awake every 15 minutes. Finally at 5am fell asleep. Had itchy chest. Doctor said cut back to 1/2 pill which I did for 2 weeks with no effect good or bad. Doctor is mad that I stoppped taking. Essentially said get out of office nothing more I can do for you I recently started on Lipitor. We are questioning whether interaction of two caused strange reaction M 62 1 days
8/22/2009
 2  movement disorder (unsure which one (ERECTIONS, BONERS, WOODIES) popping up like crazy all the time. Didn't do shit for the stiffness and freezing but made me a horny SOB. This stuff is better than viagra in that department. I've had better success with cannabis(mixed with peanut butter between 2 crackers and baked). It relieves my stiffness and pain and lasts through the next day too! Skip this crap and try cannabis(baked and ingested) for movement disorders, RLS and other neuro problems! It works better than opioid painkillers and muscle relaxers combined! M 29 2 days
7/9/2009
 1  parkinsons my grandfather has parkinsons right now and he has been on mirapex for 8 years and he recently came off of it for various reasons. He is now experiencing panic attacks and has worse health issues. I would never recommend this drug to anyone. I have watched him become progressively worse and it is awful. M 73 8 years
5/29/2009
 1   RLS My husband has been on mirapex for about 12 years. He has uncontrollable actions. From fishing for hours,golfing, spending hours playing unline poker(morning, noon, night), shopping online, playing poker twice a week in our community, and now started driving 50 miles to a casino. What ever he does, he does it to the extreme and coversup and lies about the time he fill his addiction. The doctors just keep increasing his dosage. He falls asleep without warning, lies, mentally and verbally abusive, He can't just rest, he has to be filling one of his addictions. He now takes two or three 1.5 mg day. Along with 0.5 mg Clonazepam and prozac. (He just stopped the clonazepem, after a recent eppisode where he couldn't even talk.)It is distroying a 39 year marrage. HOW does he get off this terrible drug. M 57 12 years
8/13/2009
 1  Parkinson's Serious impulse control problems, hypersexuality, depression, craved risk and walking zombie sleepiness. Went from happily married to affairs, 800 sex chat lines, pornography and "massage therapists". Could no longer drive due to sleepiness. Lowering dosage and gradually stopping mitigated all symptoms. While on this medication I almost completely destroyed my marriage and family. I was out of control. I became manic about sex. I am a respectable gentleman who had never even considered any of this in life. Now I not only have to deal with Parkinson's, I must repair a destroyed marriage and regain the of respect of my family and friends. I'm not young, I need and want my family and friends intact. The impulsive odd decisons I made in my business were costly. I am working hard to repair those problems. I am fortunate I did not harm anyone while driving with the sudden sleepiness. I fell asleep at the wheel many times. Mirapex is a frightening drug. Be careful and be very aware. The symptoms start gradually and you rationalize them away. M 63 11 months
7/23/2009
 1  Parkinson's This drug causes compulsive sexual behavior. Twice it has cost me time in jail! Under un-watchward physician care and mostly from the use of this drug that was prescribed to me my my doctors. It has cost me two felony charges and 9 months in jail! It has cost me a small fortune, and my life has been nearly ruined. I can't recommend its use. Avoid it! I feel that the company has been more than negligent in not warning the public or physicians properly of its dire effects on people, especially with a high suceptability to the adverse effects of oral medications. I was prescribed this drug twice by doctors(neurologists-so called), and twice in a very short time unbeknownst to me I began behaving in compulsive sexual way hughly untypical of myself. I ended up breaking the law and spent time in jail and lost virturally all I owned! I was living in a place where there were few people whom knew me well enough to properly detect that something was very wrong and that and inept "doctoring" and the very compounded effects of a very dangerous drug, -specifically MYRAPEX- I found myself in jail and a having become so compulsive in my behavior from the side effects of this drug that I became criminal in my lifesyle and mental state of mind. This drug is dangerous. The makers of MIRAPEX owe me big time! They taken no steps to comp M 52 2 times
9/13/2008
 1  parkinson's disease It started off slowly, but my neurologist warned me that it could happen. I experienced severe hypersexuality, Manic depressive behavior, OCD, gambling, overeating, sex phone calls, paranoia .... My life is turned upside down. Things got so bad I considered committing suicide. I drank and smoked pot to try and feel better, but it only made things worse. If you are young and taking this drug for Parkinsons ( I took 8mg a day.) STOP NOW. It almost cost me my life, my wife, my family and my job. M 50 8 years
9/13/2008
 1  Parkinson's Disease Taken by my 88 year old father. Developed insomnia - awakening at 3:00am, compulsive eating - upset his diabetes control, compulsive repetitive behaviors, severe swelling in feet and ankles, hallucinations and irrational behavior. This was a nightmare!!!! He never did work up to a maximum dose, his symptoms and behavior got so bizarre, we insisted the neurologist wean him off this drug. He is still recovering from the damage done by three months of Mirapex! M 88 90 days
6/13/2008
 1  fibromyalgia weight gain, sleeploss, memory loss,obsessive/compulsive behavior,falling asleep during the day When I first started taking mirapex I was happy with the increased energy. My dose was gradualy increased to 6mg at night. Over time my behavior became worse and I realised I had to stop taking the medication. I quit gradually with my Drs. orders. I have since had several bouts of severe depression and am still in the last one with strong suicidal thoughts/intents to the extent that mental mealth professionals are trying to get me hospitalised. M 64 7 years
3/30/2009
 1  Parkinson's disease Manic behavior, compulsive gambling, binge eating, swollen legs and feet, insomenia--this drug has ruined many, many lives. Be very careful! I know of a doctor, several attorneys, a nun, ministers, bankers, policemen--all of whom have had their lives ruined by this drug and the manic, compulsive behavior it causes. It is time for Boehrilnger Ingleheim to do the right thing by these people whose lives have been devastated. These people's suffering has spared someone else from enduring the hell that Miarpex can cause. Beware! I never thought it could happen to me, but it did. Remember that this is a medicine that affects your brain! M 61 5 years
7/27/2008
 1  PD My husband (73) has had PD for 15 years. The neurologist prescribed Mirapex. It was the worse thing the doctor could have prescribed. He became a sexual monster. The longer my husband was on Mirapex the worse the symtons became. He became very sexual aggressive and I feared for my life as he started raping me several times during the night. I could tell that he did not know what he was doing as his eyes were blank. It also made him confused and forgetfull. He could not remember what he did to me. After the medication stopped he was like a new person. When he took the medication he would have freezing spells and had many falls. He no longer shakes and walks much better no more freezing spells and he is much happier and alert. He also sleeps much better during the night. M 73 3 years
3/29/2009
 1  Bipolar Illness Extreme Nausea and weakness. Started by second dose. Stopped it was so bad. Mild OCD-like symptoms which have stayed. Certainly not worth the bother as it removed all quality of life that might be gained had it worked. M 45 3 days
3/24/2009
 1  RLS Compulsion, heightened sexuality, affected normal judgment. I have been away from Mirapex now for 5 years and want to offer perspectives from a distance. As you can read from the many comments below, this drug affects people very differently. It was very bad medication for me, even at low dose. It didn't perceptively help my restless legs. What I didn't like is that the drug taker doesn't realize the side effects. For me the side effects were impairment of judgment, non-gambling compulsiveness, and heightened sexuality. As to judgment, something about which I am normally praised, I describe the effect as juvenile - not caring about the results of actions. As to compulsiveness, my focus was a house remodel project, for which I was totally absorbed and spent way too much. As to sexuality, I just had a heightened sense of sex and got way too close to a fellow worker. That almost ruined my 35 year marriage, but my wife, a psychotherapist, knew something wasn't right and checked on Mirapex. It takes a long time to get Mirapex fully out of your body, for me at least 6 months. Mirapex could have been a disaster for me if I kept taking it and if I increased the dosage. My wife also found a potential connection between Mirapex and a family history of manic-depression, which my father had. My advice: if you take this medication, be very aware of your individual results and be very open with your caretaker about what is happening; the side effects can be very subtle. M 68 1.5 years
.5 MG 1X day
1/2/2016
 1  restless leg My father committed suicide. At the end of his very short letter he said "my mirapex has messed me up". M 64 1 days
3/11/2015
 1  RLS Horrible nausea, vomiting M 49 1 days
.125
3/12/2015
 1  Parkinsons Compulsive drive towards non-typical behavior which seems to circumvent rational oversight and sense of responsibility. As a result, my wife is now considering divorce. I would like to communicate with someone who has also experienced this compulsive drive to understand if your experience is similar to mine in the sense of how much conscious control we have or does it circumvent \ bypass the normal thought mechanisms. Your help could help me save my marriage so thank you in advance. M 53 4 years
11/16/2009
Email
 1  RLS Addiction to gay porn, spent all day sleeping as dreams were so much better than my real life, started smoking, scratch cards, short term memory problems, lying, erectile dysfunction, compulsions, two pulmonary embolisms pretty much screwed up my entire life. Still get no enjoyment from anything just waiting to die. Still erectile dysfunction although addictions have gone but short term memory rubbish. Wish I had never seen the news article and asked my doctor for it. Cured my RLS on day one with half dose, but side effects, and on-going side effects are life changing. Probably worth it for Parkinson's patient as they are going to die anyway. Cured RLS by taking 30mg Codine Phosphate Hemilhydrate/ Paracetamol 500mg (called solpadol) before bed, no side effects as yet. M 40 2 years
.5mg 1X day
1/13/2014
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 1  Parkinson's this medication seems to destory all emotions. There's no right/wrong. no good/bad. Nothing to cry about. M 60
1.0 1X day
3/7/2011
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Patient History
 1  Parkinson's Horrible reaction. All PD symptoms became dramatically worse within days of starting Mirapex. I quit the drug after 4 days. I've been off the drug now for almost 3 weeks and my symptoms have still not returned to their pre-Mirapex level. Shuffling gait, constant spasms, frequent muscle cramping, unsteadiness-all much worse than before I started Mirapex. I also take Azilect and Propranolol. Has anyone else experienced this or heard of anyone who has. I'm quite anxious about how much longer the intensified symptoms will last. My neuro says she's never seen this before. Doesn't know what to do. Any ideas/info would be greatly appreciated. I understand my reaction is not typical, but I think the drug warrants much stronger warnings re side effects, and perhaps even to be taken off the market. My reaction has been dreadful, but based on so many other postings on this cite, Mirapex has absolutely devastated many lives. I have urged my neuro to never again prescribe it for anyone. M 56 4 days
.25 3X day
1/4/2011
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