MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22


RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Restless Legs Pain in legs and feet, Obsessive Thoughts, Obsessive eating, extreme lethargy, morning hangover, Sleep is all I think about. Completely stopped severe RLS symptoms, complete lethargy not worth it though. M 39 30 days
8/15/2008
 3  RLS Worked on my RLS, which was a great releif after more than 30 years suffering and nothing else helping. Found had to take it 3-4 hrs before bed to take effect. Was not told of any side effects until started to wonder what was going on. Started out on .125 and had to increase to .375. Side effects kicked in at .25mg. Side effects include legs hurting upon awakening, muscle cramps that effect my walking, feet hurting all the time and MAJOR mood swings, OVER HEIGHTENED SEX DRIVE, desire for kinky/overt acts with wife, but find myself thinking about other woman all the time (never cheat and wouldn't), desire to pickup drinking and tabacco use that I have been 15 years without. Anger issues that I have alway controlled, depression/manic episodes, OCD type activities, suicidal thoughts. Found this site and working on getting off Mirapex now!!!! Was wondering why my life was unraveling (I am a professional in the fire service and stable person) and getting worse the past 6 months (increased the dose to .375 6 months ago). Wife does not understand what is going on, even though I have asked her to read this site. Marriage may be on the rocks and not savable after 33 years, even if I get off because of my uncontrolled sex drive towards her and way I have treated her. This is NOT WHO I AM! Very frusterated right now. But hope is on the way now that I know what is causing it. M 49 3 years
5/6/2009
 3  RLS Weight gain, increased sexual desires, RAGE, falling asleep while driving, aches and pains, RAGE, obsessed with death although not suicidal, confusion, RAGE, overall addictive behavior, tremers, balance issues, pain, and did I mention RAGE. My RLS is fine though. (.75 nightly) Tried to quit cold turkey and spent two days flopping like a fish. The RLS came on like a f***ing bullet train over my entire body. However, even though I was so tired, the aches were gone. I'm back on it now and back to being a psycho. AND WHAT ARE YOU LOOKIN AT!!! Sorry, I just do that from time to time. The RLS is fine though. M 39 10 years
7/22/2009
 3  RLS Nausea, sleeplessness I'm taking .125 (I think) as needed. It does knock down the twitching, although not completely. The nausea the next day ruins it for me though. Since I don't take it regularly (perhaps once a month or even less), I don't suffer from the other side effects mentioned. M 45 2 years
7/7/2008
 3  RLS Has radically altered my sleep patterns. Before taking Mirapex my lifelong sleep pattern was difficulty falling asleep (often 2-3 hours), but then sleeping through the night afterwards. On Mirapex, I can fall asleep very quickly at night (as well as during church, in meetings, watching TV or in Movie Theatre), but generally wake up at 3-4am and can't go back to sleep. Have also had a lot of sticky phlegm in throat that stated about the same time as starting mirapex, that contributes to snoring and waking frequently at times. Have also seemed to have struggled more with some compulsive behaviors (primarily eating) that may be related. Mostly controls RLS symptoms. M 45 18 months
7/10/2008
 3  RLS Gained 60 pounds since taking Mirapex March of 2007, COMPULSIVE shopper, I owe $20,000 in credit card payments, binge eating, addicted to chocolate, severe sores and rashes on my arms for over a year, haven't slept an entire night, I wake up every few hours, tired all of the time. The requip that I had been taking for RLS hadn't worked anymore, so my Dr. put me on Mirapex and it was right after I begain the drug that my arms starting breaking out. I walk around on the hottest of hottest days in jackets and anything long sleeved because I'm so embarrassed ofmy arms. DOES ANYONE KNOW OF ANY OTHER MEDICATION FOR RLS THAT WOULD WORK, I'M DESPARATE. THANK YOU. RESTLESS IN SARASOTA M 55 15 months
5/26/2008
 3  RLS Anxiety, lethargic, low energy especially in the AM,paranoia, a need to go back to bed after being up in the AM for an extra 20-30 minutes,memory loss, weight loss, dry mouth,ankle & hands swelling, lower motivation. AM hangovers. The side affects took time to develop and became much worse the second year. My sleep has become deeper and slightly longer, 5.5 to 6 hours. Minimal S/S of restless legs in the evening. Falling asleep early in the evening. M 70 2 years
7/19/2008
 3  Parkinson's I was diagnosed with Parkinson's disease in 2003. Started on Mirapex after one year. I became a compulsive gambler and gained about forty pounds. I have trouble sleeping all night and tend to eat while awake. I fall asleep during the day and have fallen asleep while driving resulting in several minor accidents. I've also had many close calls. The medication helps with my symptons but not sure its worth it. I will ask neurologist about other medications. M 56 6 years
2/16/2009
 3  Periodic Limb Movement Disorder Hallucinations when I took too much, none at my regular dose I got put on this for PLMD and for the first two months it worked great, but then it slowly lost efficacy to the point I had to double or even triple up on my dose to get relief. One night, I took five of them and had mild hallucinations. My doctor switched me to Flexeril after I told him it was no longer working and he told me this was common for this med. He said nearly all patients experienced a burnout on it and it completely stopped working for them and they had to switch to something else. M 29 5 months
0.25 1X day
12/17/2014
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 3  RLS Fatigue, falling asleep during the day, morning nausea, muscle weakness. I was prescribed this drug about a year ago for RLS. at a dosage of .125 which seemed to work if taken 2 hours before bedtime. Recently it was not working as well and my doctor increased to two 0125 tablets. I guess one question I have is what problems are side effects of the drug or just the body getting older, like muscle weakness. However, lately I have felt like I wake up in a fog even after getting 8-10 hours sleep. This weekend I took my motorcycle out of the garage and after a short ride returned as my balance and general control was off. I also felt mentally impaired, just not sharp. I now can fall asleep at the computer with no effort at all, yesterday I fell asleep and didn't even realize it. As far as the RLS the drug works! I am now thinking about getting off the drug and trying to find some other source of relief from RLS. M 63 1 years
0.5 1X day
7/11/2011
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 3  RLS OCD, irrational irritation, hallucinations, concentration problems, falling asleep(narcolepsy), extreme sweating with sweet vanilla scent, swollen feet with discoloration, weight gain. I increased the dosage about 2 years ago and 1.5 years ago I lost my job with a very prestigious university because of the side effects. I was not even aware of that I had side effects until I read the comments on this site. I need to get in touch with others that have taken legal actions, please email me if you are taking legal action. M 43 10 years
2.8mg 1X day
9/20/2010
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 3  It was the only med that worked After I had been taking Mirapex for about 3 years, at gradually increasing dosages, I started gambling. I did not connect this to the Mirapex until I read some things on the Internet recently, but previous to the onset of this compulsive behavior I had been very proud for years that I had never gambled, and that I had never even played the lottery. I have also been diagnosed with sleep apnea (severe) and have increased weight, but do not know if Mirapex is the cause of those things. For many years, I called Mirapex, my "miracle" drug, but now I am not so sure. I don't know what to do though, because I have an advanced case of RLS, and I can't live without a medication to relieve those terrible symptoms. By the way, I describe it to others in this way: It is like I am a human capacitor, and I can feel an electric charge building up in me, which then discharges causing my body to spasm. But it feels as if there is an almost constant low electric charge going through my body. It is terribly uncomfortable. M 55 8 years
4.5 MG 1X day
6/7/2010
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 3  Parkinson's Mild occasional nervousness, dizziness and hillucinations, mild nausea at the beginning, insomnia occasionally, I suspect it has increased episodes of irregular heartbeat I've been experiencing lately. Has helped with pain, flexibility and general mood but tremors actually seem to have worsened. M 61 3 months
1/13/2007
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 3  RLS severe leg cramps after 1 year I have been taking mirapex for 1 year with great success. I take 1.5 mg at night. Over the past few weeks have developed severe leg cramps during the day in my calves and back of my thighs that ae debilitating. I am considering adding at least one dose during the day to seee if that does not diminish the leg cramping. For those who are just starting, be sure to have plenty of food in your stomach when you take mirapex--it can make you very sick to your stomach, When I started taking it, i would vomit all night. M 53 1 years
7/30/2005
 3  RLS Muscle aches and soreness in legs and upper arms similar to flu like symptoms. Daytime drowsiness. Nasal congestion. Ocassional weird dreams, I started taking .25 mg of Mirapex which worked fine for a month and started to notice the day after taking Mirapex I experienced muscle pains similar to having the flu. I cut back the dosage to .125 mg and it is effective in controlling the restless legs but I still feel the muscle aches and pains. My neurologist says Mirapex should not cause muscle pains. I was taking Requip before switching to Mirapex. Requip was effective for about six months and then I started getting severe augmentation so the doctor started the Mirapex. I sleep through the night but feelsleepy, achy and sore most of the next day. I take Mirapex about every other night and the day after I do not take it I do not experience the muscle aches and pains. M 53 4 months
10/8/2006
 3  RLS Not sure if it's from the mirapex .5mg 2xday or one of the other drugs I take for RLS... often have loose stools (could be my horrible diet), occasional problems with my equalibrium and walk into door-frames, etc. often a little drowsy, seldom hungry. It seems to be helping (partly due to 2 other meds I'm taking?). My wife told me my right leg used to jerk about every 40 seconds when I was trying sleep. Now it probably only jerks 3 - 5 times all night. And the jerking is less violent. It almost looks as if I was intentionaly streching my leg. But I can still feel that damn sensation leading up to a movement. M 42 3 weeks
5/13/2004
 3  rls .25 mg dose worked well in combination with 1mg Klonopin for about 2 weeks, then became ineffective. Doctor increased dose to .5 mg and this worked well for another week or so until tried to remove Klonopin. Problems included leg spasms, anxiety, difficulty falling asleep, awakening during nite with anxieties, muscle soreness, tiredness all day. Still trying to get the right dose and will try taking early in evening versus one hour before bed. Would like to quit Klonopin, but must wait and see. M 64 4 months
8/20/2004
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 3  CATAGORY 3 Parkinsons Disease Drowsyness especially if I am tired. Loss of attention. I am at the Max recommended dosage 4.5 mg daily and the tremors don't stop. Supplimental doses of Artane started. M 50 5 months
7/20/2003
Email
 3  parkersons it helped my trmor however i was very consipated M 68 30 days
3/23/2004
 3  rls clenched teeth, causing fungus on tongue relieves rls, but not plm M 55 3 months
4/28/2004

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