MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  rls extreme fatigue, dizzyness, vivid nightmares, headache, spaced out,hallucinations THIS DRUG SHOULD BE BANNED. THE WORST DRUG I HAVE EVER USED. I COULD ONLY ENDURE IT FOR 10 DAYS AND WOULDNT WISH IT UPON MY WORST ENEMY M 38 10 days
10/5/2007
 1  RLS I experienced great relief from the drug, but am now battling serious gambling issues, which are causing excessive stress in my family. I started out when a doctor FINALLY decided to treat me for RLS amost five yrs ago. None of the other doctors believed what I was telling them as symptoms. They continually gave me "pain killers" to put me to sleep. I finally got Mirapex two yrs ago. I started with one .25mg prior to bed, but have now worked my way up to 3/4 .50mg pills prior to bed to ease the twitching. The torture of the foot pain and lack of sleep has gotten much better, but I have now had to refinance my home to pay off all the credit cards I max'd out for cash advances to buy scratch tickets and lotto tickets. I tell myself how foolish it is, but then find myself at the counter buying them. I have even lied to my wife about my gambling. THIS IS NOT A DRUG TO BE TAKEN LIGHTLY!!!!!!! I am working with my primary now to get off of this and find a replacement drug. DO NOT TAKE THIS DRUG!!! THE SIDE EFFECTS ARE NOT WORTH IT!!! M 58 1 years
10/9/2006
 1  RLS I was saddled with headaches, foggy brain, and weight gain, while the Mirapex did not help my RLS. Upon quitting use, my headaches are gone, my head is clear, and I am once again losing weight! M 48 4 months
10/24/2008
 1  Parkinson's Hallucinations, loss of appetite, confusion, couldn't walk, talk or eat without assistance. My grandfather was on this for over a week. He went from being a fun, joking around kind of grandpa, to not knowing what was going on around him, hallucinations, horrible nightmares, could not feed himself, no control over his feet or hands, constantly reaching for things that were not there, confused, terrible diahrea, tired all of the time, etc etc. We thought my grandfather would eventually not even know who we were...it was such a dramatic change in him. He could barely walk and needed 24-hour care. Couldn't follow directions from the PT or the OT, very, very confused. After my mother told the doctor to take him off of the drug (he was in the hospital at the time), he had a DRAMATIC change and was back to "normal" in two days. It was amazing....we will NEVER, NEVER allow the doctor to put him on this again. BEWARE!!! We actually admitted my grandfather into a nursing home (because the hospital was discharging him and the doctor said he needed 24-hour medical care). M 2 weeks
12/25/2007
 1  RLS - Light To Moderate Headaches. I like, NEVER get Headaches (once a year MAX)... so having a headache was quite surprising. 0-Zero improvement in RLS. 0-Zero improvement in RLS. Trials of Mirapex as well as Requip both led to Ansomnia for me... so it could be me. However, Requip did not lead to Headaches and after seeing numerious other comments mentioning headaches - as well as a life history (of 33 years for me) basically headache free: I think it's fair to say that Mirapex is the source of my headache at this moment. It's 5:52AM, I've been up all night with a headache from Mirapex. M 33 5 days
12/2/2007
 1  Parkinson's I am writing on behalf on my deceased wife. My beloved took the medication to "smooth over" her off periods. She took it for over 5 years. Without our knowledge she became an OCD obsessvive compulsive disorder (diagnosis from her neurologist). She spent $180,00.00 on things she could have done without. We did not know the bad side effects. She had terrible nightmares and could not sleep through the night for the last five years. DON'T TAKE IF YOU DON'T NEED IT! LOOK FOR OTHER SOLUTIONS M 62 5 years
3/24/2008
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 1  RLS Awaken every hour since starting Mirapex. Can't go back to sleep for 2-3 hours. Then after another hour of sleep I awaken again. This has not helped me get any more sleep than before starting Rx. Extremely fatigued during the day. Symptoms of RLS began 30 years ago. Slowly they became worse. Sleep Disorders/Neurologist prescribed Mirapex 0.125mg for 5 days with no significant change. Dose was increased to 0.25mg by Dr. Mirapex is NOT a wonder drug for me. M 72 6 days
4/8/2008
 1  PD Compulsive gambling; swollen feet and legs; insomenia; rash; manic behavior; ADD. Watch out--this is the drug from hell. Mirapex completely ruined my life. I had no choice about Parkinson's disease, but I should have had a choice about Mirapex if only I had been warned. M 61 5 years
4/20/2008
 1  RLS Mirapex initially worked, but overtime it exasperated my symptoms of RLS, thus my dosage was gradually increased over 10 years along w/the severity of the RLS symptoms. While on Mirapex, I had increased & chronic headaches, weight gain, edema, OCD, manic-depressive disorders, memory loss, unable to stay on task, impaired normal thought process and reasonable decision making process, restricted learning capabilities, obsessive spending on Ebay, and poor behavioral habits. I am convinced that while on Mirapex this drug cost me friendships, job promotions, respect in the workplace, and reduced my quality of life to a point of wanting to take it. This drug almost cost me my job and a very loving family, thank God I did not. After learning of the side effects associated w/ Mirapex, I stopped using this drug. Initially my RLS symptoms were extreme & server, after about 4 weeks, these symptoms subsided and now my RLS symptoms or very minimal and controllable. The side effects that I was experiencing have drastically subsided or gone completely. It is my hopes that this drug will be taken off the market, and for no one else to have to endure this fate. M 49 10 years
10/29/2008
 1  RLS Uncontrollable gambling causing loss of thousands upon thousands of our savings, excessive weight gain, increased restlessness and uncontrollable muscle movements all over my body. Waking up in strange areas of my home. No memory of the night or going to bed. Increased forgetfulness. Have developed a "I could care less attitude" in all areas of my life (including family, pets, taking cre of myself and my home, not paying bills on time, lethargic and sleepy, cannot concentrate on anything, easily aggitated). My life has been turned around from 100% good except my problems with restles leg syndrome to me ruining not only my life, but my wife and everything around me. DON'T START IT! THE GAMBLING SATEMENTS ARE REAL! I HAVE LOST NEARLY 50 YEARS OF SAVINGS AND POSSIBLY MY WIFE M 46 1 days
8/18/2007
 1  RLS and FMS Rash on legs, it did not seem to work. My doctor insisted I keep taking it. I stopped due to arthritis. See additional comments. I saw an orthopedic surgeon due to shoulder and arm pain. X-rays showed arthritis. He said in the distant future I would need surgery to remove it as it was impinging on those nerves. I saw him again a month ago and he said the arthritis had grown the equivalent of YEARS. He is recommending neurosugery to remove the arthritis. My family doctor said he has never heard of such a thing and said I should take steroid shots in my shoulders. I quit taking the mirapex and the RLS was much worse for about a week and then went away. It seems there was no difference in my FMS. If you have any hint of arthritis, be very careful with Mirapex. M 53 3 years
5/30/2007
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