MIRAPEX Reviews (PRAMIPEXOLE DIHYDROCHLORIDE)

Average Rating: 2.8 (431 Ratings)

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 EXTRAPYRAMIDAL MOVEMENT DISORDERS

 Type: Rx Drug

  

MIRAPEX  (PRAMIPEXOLE DIHYDROCHLORIDE):  Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome"). This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep. Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.   FDA Approval Date: 1997-07-01 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIRAPEXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Parkinsons Huge boost in energy and therefore improved speech and balance, etc on 2 tabs, 3 times a day (with Azilect)but badly disturbed sleep on 3 tabs, 3 times a day which obviously brought on fatigue. Neurologist and PD nurse suggested going back to 2 tabs and I feel pretty good generally and although there is very little improvement in my speed of movement in my weak arm, the energy levels more than compensate. Mood also much better. M 40 60 days
4/30/2007
Email
 4  RLS none originally prescribed .50 mg at bedtime. I found that .75 mg works better than .50. Occasional relapse with RLS happens but is nowhere near the severity it was pre-Mirapex M 37 4 years
7/14/2005
 4  Restless Leg None It has aided sleep problems, but not done away with. However other sleep problems could be related to apnea. M 38 9 months
4/27/2007
Email
 4  RLS 30 lb weight gain over 6 months, hot hands, ankle edema. works great when I take it at the right time. Weight gain is depressing and I may have to back to Requip which did not work as well. M 45 6 months
7/28/2007
 4  RLS First year had terrible bouts of sudden sleepiness (like "crashing") and terrible nausea and sometimes vomiting-all during the first year, though, for my RLS it was miraculous and still continues to help me tremedously. I do have extremely vivid nightmares and also somewhat addicitive types of behaviors which I did not know until I started researching the medication, could even be caused by it. Overall-I do not think I could function without it as I have a very severe case of RLS M 42 4 years
4/29/2007
 4  RLS works well for my RLS---I'm now sleeping most of the night for the first time in my life! One major side effect though, I am developing joint pain in my ankles, arms and especially my wrists and fingers---seems similar to arthritis pain. The pain seems to be getting progressively worse. Since I am a songwriter and guitar player by trade this side effect is very worrisome. Anyone having the same problems with this side effect? And if so does it get better with time or worse? M 57 6 months
10/5/2006
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 4  EARLY PARKINSON'S SLEEPINESS IN EVENING M 63 5 months
6/14/2005
 4  RLS None yet. Have rls in legs and arms/upper body. Been on it about 8 months, noticed recently that it's not always quite as effective as it was initially, but that could also be due to poor diet or other factors. I noticed my legs really don't bother me AT ALL anymore, but arms twitch lately. I plan to try changing diet/exercising. M 27 8 months
4/24/2006
 4  RLS I do not sleep well at night. Also have sleep apnea and hypopnia. Very tired and drowsy during the day. Difficulty concentrating. I do not have as much energy as I would like, and have a difficult time staying awake at work when I'm using my computer (ever nod off and type 1000 x's?) My mood seems to be down most of the time, some times I am just plain crabby. Neurologist prescribed Mirapex starting at .25 mg but told me I could go as high as 1.5 mg per day. Currently take app. .75 mg at night. It works well if I take it before eating dinner. Usually find that it doesn't have much effect if I have had a meal first. My doctor put me on Celexa for anxiety and to help with my sleep disdorder. Seemed to work very well, until the insurance company switched me to generic Celexa. All benefits vanished, so I quit the generic. This may be part or all of the reason for the irritability, but loss of sleep and drowsiness must have a part, also. I have been thinking of trying ReQuip, but one of it's side effects is drowsiness. May not be a good idea. I also take 160 mg of Diovan for moderately high blood presssure. I have a CPAP, but rarely use it due to mask discomfort. If I could wear it regularly, it would probably help. M 52 4 years
5/21/2006
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 4  Restless Leg Syndrome Compulsion to purchase items in general but I can control it. I have severe RLS so that without drugs I stay up 24 hours a day and spend most the time pacing because I cannot even sit down. With Mirapex taken at night and other medications during the day I am able to lead a normal life. Without sleep I cannot work or enjoy life at all. Mirapex has been the only drug that allows me to live a good life. I probably should give it a 5 but I am giving it a 4 because of the fact that it gives some people compulsions such as I have with it. M 57
.50 mg 1X day
12/16/2012
Email
 4  PLMD/RLS If I take too high a dose it tends to keep me awake at night. Has greatly reduced my involuntary leg movements at night. I no longer have to get up out of bed to make my legs stop jerking (well hardly ever). I started on 1/2 of a .125 mg tab. I've gradually had to increase that to 1.5 tabs over the course of about 2 years. The trick is finding the minimum effective dose. If I take too much I will lie in bed awake all night feeling wired even though my legs are not jerking. M 55 2 years
3/13/2007
 4  RLS No apparent side effects I am taking 0.25 mg. My wife reports that my RLS is reduced, but not eliminated. I notice a significant improvement in my sleep. Also have OSA and have used CPAP for 6 years. Between CPAP and Mirapex I have slept better in the last year than I have for decades. M 49 1 years
1/7/2007
 4  RLS 1st week, I had trouble sleeping and had bouts of nausea. This got easier to deal with by week two. Went from .125 mg to 3x .125 over the next two weeks. Sometimes take an extra in the late morning when I need it. Wake up at 3:00 AM but can fall back asleep and usually get 5-7 hours. This is the first medication that has actually worked. Some daytime RLS still, but OK at night. Side effects mostly gone by 4th week (I'm on week 5 now). I have tried klonopin (one year..too addictive. Took 4 months to ween myself from it) and ReQuip(stomach pain and medicated feeling)Staring on .25 mg does 2x a day next week. Hope that is as much as I'll need. M 35 5 weeks
12/17/2005
 4  Parkinsons Weight gain, sleeping problems Works well for me so far. I also take Sinemet so don't know if Mirapex is helping or not, but with the minimal side effects, I will continue taking it. M 59 1 years
.25mg 3X day
1/26/2011
 4  Fibromyalgia Pros: Can tolerate more foods. Have more drive. Have less pain. Cons: Quicker impulses. Nausea. It works for me. The side effects are annoying but its fine. I think people need to watch themselves carefully during the first months. Also, if you dont have to take it during the day time then dont. Take it before sleep. It works best this for Fibro anyways. M 31 3 months
1.5@night 1X day
2/25/2011
 4  RLS Initial nausea at first. The first morning I thought I had the flu. I reduced my intake to a quarter of a pill and gradually worked my way up to half a pill a day. Nausea subsided with no other side affects. My doctor prescribed Mirapex after I developed minor anaphylaxis to Ultram. The withdrawal from Ultram was excruciating. Mirapex has been a lifesaver for me and has practically eliminated my RLS. I haven't developed any of the other side affects to include gambling or compulsion. I think these person specific. Everyone reacts differently to medications. M 41 2 months
,25 MG 1X day
11/22/2012
Email
 4  Head injury that gave me rls I stopped mirapex for requip but had bad withdraws from mirapex body locking up like my jaw and every joint on my body hurt I have now returned to taking mirapex M 55 10 years
3 mg
10/9/2015
 4  Parkinson's Dull headaches when I started the medication. Dull headaches subsided after 2-weeks. The tremor in my left hand is not as prevalent. The Mirapex has definitely improved the tremor significantly. I have the beginning stages of Parkinson's and I work full-time. The medication has not affected my memory or sleep. M 57 1 months
0.25 3X day
6/11/2015
 4  parkinsons hallucinations, M 56 4 months
5/30/2008
 4  rls none M 73 3 years
3/29/2009

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