SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Insomnia BE CAREFUL WITH THIS DRUG. It is not tested enough -- NOR APPROVED FOR -- Heart palpitations, shortness of breath, rapid heartbeat, couldn't get up in the morning, nightmares. At first, I thought this drug was great because it cured my horrible insomnia with Effexor. But then, all those odd side effects and fatigue happened, so I stopped using it. F 41 7 days
1/23/2009
 1  Poss. misdiag. of dprssn for bipo 2 After first night of 50mg the next morning I had the worst "charlie horse" in my left calf I've ever had. My RX was for 25mg in a.m. 50mg in p.m. The following morning the pain lessened some but never went away and I was forced to hobble when I walked. After a week of this I call the pharm. and she said that I probably needed to find another med. and then I called the emergency psych. and she told me to take one more the next night and then quit. She emailed my psych. and told him she'd taken me off. He nor his nurse think that the seroquel was the problem and that maybe the "heat" or low potassium was the issue. I asked then shouldn't I get my levels tested. And she said no, just wait a few days and start again. Screw that, I wasn't playing lab rat! I called my m.d.'s nurse & she put in a blood work order for me. All my electrolites ect. were just fine. It's been over a month and I still have a rock solid calf. I limp all the time and it's thrown all the rest o I waited a week after this "new" diagnois'was made to make sure that I really needed it and that I understood all the side effects. I was scared to death of this med. Muscle stiffness was all that my prescrip. made reference to that would even remotely cover what I experienced, until I read of 2 others here that had calf and foot cramps. I knew it was the Seroquel. F 46 7 days
9/28/2005
 1  anxiety/major depression The seroquel certainly decreased my anxiety, however, it made me so depressed that I think I was suicidal I was just too tired and my brain was too foggy to bother acting on my suicidal urges. I felt very flat and like I couldn't care less about even the most alarming things. I also had an increased appetite and intense hunger in the morning. I am glad to be off of this medication! F 24 7 days
100 2X day
10/20/2010
 1  Insomnia Memory loss, drugged feeling, muscle weakness,confusion,rapid eye movements,temors,feelings of numbness. I am writing this from from a hosptial bed...I started Seroquel 1 week ago, on the 7 day I became, confused, weakness of muscles unable to stand temors of the legs and arms, rapid eye movements, I could not tell anyone my date of birth, was running fever, and shaking uncontrolable. I was rushed to the ER by ambulance and admitted to the hosptial to began my "detoxic" of the horible medication. My second day in the hosptial I have delevloped pneumonia and the withdrawls from this medicine has been awful....I am having muscle temors still my whole body is stiff and I am barely able to walk. Seroquel should be taken off the market I can see where this medication could be deadly. F 41 7 days
300 1X day
11/22/2010
 1  Bipolar II / Depression Violent fainting attacks, bloated/very uncomfortable stomach, nausea, tremor, hot and cold flushes, burning sensation under the skin, headache and a feeling of pressure in the head, excessive sweating or shivering, tachycardia, heart palpitations, insomnia, neck pain. Last in the line of attempted treatments for my bipolar II / depression. Stopped it after only one week at the lowest dose due to nasty fainting attacks combined with random selections of the other side effects I listed. I have never felt so physically ill before in my life, and was hospitalized one night due to it. Now, almost three weeks after stopping, I feel significantly better, but still far from good. Still have occasional attacks of low to medium severity and constant insomnia. M 26 7 days
25 1X day
2/23/2012
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 1  Depression RAGE RAGE F 34 7 days
1X day
9/26/2011
 1  Panic attacks, anxiety and insomnia Shortness of breath, daze, slept good a couple of nights. Then started feeling anger Nausea, bitter taste in my mouth. The 7 might around 3 woke up shaking felt poisoned, couldn't sleep felt horrible. I don't understand why Dr's prescribe this drug. 8th night event bough I took my dalmanre and lexapro couldn't sleep. Slept for a couple. Of hours and woke up withhad a panic attack and shaking. Right know I feel bad and have an sppt with my Psychitrist . Stop taking this med is poison for your body F 51 7 days
50
11/22/2011
 1  Ptsd Couldn't swallow ended up in the er Bad drug very scary M 52 7 days
200
1/31/2017
Email
 1  Sleep and racing thoughts Just an awful drug for me. Instant zombie on lowest of dosing and no cease of racing thoughts. Did help with sleep the first few nights. Extremely powerful and caused/lead to some black holes memory wise for me. This one wasn’t for me. I was groggy even minutes after taking it. Memory gaps and lethargic state were terrifying. 48 7 days
12/10/2019
Email
 4  PTSD, Sleep Disorder The side effects I’m currently experiencing are: feeling tired during the day and difficulties concentratin. Due to PTSD, I sleep very little and awake often resulting in 2-years of sleepless nights. Without question, the Seroquel has helped significantly with sleep to include remaining asleep throughout the night. My wife states, I move very little and have been snoring which is a relief to her knowing that I’m finally getting some rest. I don’t awake during the night to screams and images in my mind which we both are grateful for. I’m concerned about long-time usage and the difficulties I’ve experienced in concentrating. The benefits currently outweigh the side effects and I’ll closely monitor changes with my doctor to determine ongoing treatment. M 39 8 days
4/17/2007
 3  BP Difficult to rise in the morning. Sleep 9-10 hours. Thirsty. First two days felt drunk the next day. Forgetful on small details, which scares me a little. I am just in week 2. It has calmed me down. I have gotten a lot done at work as a result. I had a difficult thing to do this week and I was calm doing it, which is a real positive change. My Dr. suggested 50 mg, but I have only taken 25 mg and so glad I did. F 38 8 days
3/25/2009
 3  Cyclothymia (Bi-Polar II) Taking seroquel in hopes of solving mid-level cyclothymia. At this point I can't say if Seroquel is helping or not. I haven't had anymore drastic cycling however, I have stopped taking the SSRI I was on that was probably making the cylcing worse. I started with 50mg and I'm up to about 175mg a night. I don't really sleep too well on this drug, I wake up several times a night. A little grogginess in the morning, but it wears off. This drug has a very short half life, so I don't understand the chronic day time drowsiness people commonly complain about. I'll give the drug another week, if things don't better I'll dump it and attempt to let my brain work this out on it's own. This drug is not nearly as evil as people make it out to be M 33 8 days
4/4/2007
Email
 2  Anxity,seeing things,hearing things Constipation,crushing chest pains,vivid dreams,zombie like could not function,slow alertness,nothing really matter. I slowly was introduced to 300 mg but the night I took it I thought i was stroking out chest crushing pain my heart felt like it was about to burst right out of my chest. Next night i broke it in half and still was like a zombie.This is an awful medication to be on. I was prescribed this because I had real high anxiety and thoughts of crazy things and seeing things that were not there my doctor said that was because of the prozac. The only thing I did like was the crazy dreams very vivid almost real like. F 43 8 days
2/18/2008
 1  in hospital a dr. ordered it sleepwalking, delusions, crying fits, weight gain, could not think rationally I have had depression for many years (controlled with Zoloft). When my father was dying I became very agitated and depressed and decided I needed hospitalization to get me through it. I went in to an unlocked ward and that night they gave me a big dose of Seroquel (a drug I had never heard of) so I would sleep. The next day I was acting strange (I don't even remember it), so I was taken to a locked ward and the dosage of Seroquel was tripled. Soon I was basically screaming and delusional in the locked ward. My husband would visit me and kept telling the doctors I was getting worse by the day. I can't even remember seeing him at these times, all I remember is constantly waking up after having run into a wall or some other obstacle and not knowing how I got there--must have been sleepwalking a lot. Finally I got a patient's advocate to get the doctor to stop giving me Seroquel, this was probably 7 or 8 days into my stay, but I'm not sure when the drug was discontinued. My husband F 46 8 days
11/21/2007
 4  depression Sleepiness, lethargy Seroquel is a good medication if taken properly. It really helps me get a good night sleep and I dont wake up groggy. I take a very low dose, 25mg. I think the key with making this medication work is allowing enough time from the time one takes the medication to time of sleep. I usually take it 3 hours before I go to sleep and it kicks in at the right time. M 46 9 days
10/22/2007
 4  BPD II Grogginess, especially in the mornings, when taking the first dose or when increasing dosage. Usually subisded a lot on second day and even lessened as I increased the dose. "Electric" feeling in my mouth. Anxiety attacks late in the day for first 5 days (subsided after that). Crying jags for the first 5 days. Suicidal ideation days 3-5 with strong thoughts of it around day 4 and 5. I was very, very afraid of this medicine. Everything I read, not published by the maker or someone associated with the maker, seemed to be negative. There are certainly some concerning side effects, but I was bound and determined to try to make it through the adjustment period of this medicine. I have had lots of bad experiences with SSRI type AD's and expected the worst with Seroquel. In fact, I started not to take the first dose because of all the negative publicity and feedback. I kept wanting to stop during the first 5 days, but didn't. I am really glad I didn't. I made it to the target dose of 300 mg per day and am almost side effect free. I still get the electric feeling in my mouth, get dry mouth, and am sometimes sleepy, but I am finally starting to see some relief from my depression, which I have NEVER experienced in my 42 years of life. This stuff is actually working and I am only a week in. Because optimal results are not seen until 2-6 weeks out, I am excited about what's to come. I may actually start to feel better. Bottom line, try this medicine if your pdoc thinks it might work for you. Don't be scared by the hype. Be cautious, but remember that these are new generation drugs that have less side effects than the older ones did. Watch your health and be vigilant, but don't let someone else's bad experience keep you from trying something that might help you free yourself from the bonds of depression. M 42 9 days
8/6/2009
 1  anxiety and stress suicidal, weight gain, nightmares, felt like a pin cushion, and a general memory loss. Hard time focusing on anything and including who i was. also lack of energy. No sex drive.Why?????? Doctor told me she prescribed it as a substitute for xanax. If the govt won't cover it for veterans how was passed by FDA. M 56 9 days
6/2/2009
Email
 1  Bipolar depression-manic episode After taking 25mg., I went to walk my dog and had to stop moving from fatigue, muscle pain and what seemed to be blurred vision. As I increased the dosage to 150MG everything went worse: appettite increase, problems standing up, slurred speech & and phrases that meant nothing, zombie-like feelings, numbness, increase in urination, severe memory and concentration problems, lethargic. After a pretty bad manic episode I was prescribed Seroquel as an addition to the medications mix I have been taken for my disorder during the past 3 years. Seroquel should not be taken unless you suffer drom severe insomnia and/or anxiety disorders. Forget it. M 42 9 days
3/26/2006
Email
 4  bipolar mania None so far apart from a stuffed up nose. I am taking this drug for mania and psychosis. I've been sleepless for 8 days and am now beginning to get some rest. This episode has been catastrophic financially, and I have had auditory and visual hallucinations. Quetiapine has sedated me a bit( I add in a sleeping tablet) and taken the edge off the mania. I still have the hallucinations, but they are not as intrusive as they were. I also take abilify and venlafaxine, so at the moment I'm on two anti psychotics, which is not recommended in the long term. I'll come off the quetiapine when I'm a bit better, but having read the posts, I'll do it slowly. The drug has been a life saver in that it makes me drowsy, but I wouldn't take it unless I was manic. F 56 10 days
1X day
7/23/2012
 4  bipolar / insomnia I slept very well on 25mg at bedtime. I had to be sure I took it early enough so that I would have at least eight hours to sleep, otherwise very sleepy in the am. Problem is I developed mouth puckering, which my md said could be a side-effect.(dyskinea) I'm disappointed I had to go off. Hoping maybe I only had the mouth puckering because I was also on Prednisone for asthma. Maybe when done with prednisone, can try again. F 41 10 days
5/26/2005

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