SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Depression My doctor had me on 200mg, and now has me on 300mg. It makes me feel very tired most of the time, but I take it at bed time, so it does help me get to sleep at night. But even then, I still feel slow during the day, it takes a while for me to get moving. During one hospitalization, the doctor assigned to me had me on seroquel in the hospital, but didn't continue it after leaving. I felt like my ears were buzzing all the time when going through withdrawl, but after a few days it went away. I was off six months then another doctor decided to try it again. Even 200 isn't so bad, I just wish my doctor would try getting me back down to 200 or below. 200 and below I don't feel quite so tired. M 29 9 months
9/30/2004
 4  Chronic, life-long insomnia I have not experienced the typical side-effects of weight gain or the other effects I've read about. I began with 50 mg dose at night, but I was sleeping 10-12 hours, so I cut the pills in half (12.5 mg) and that did the trick. I thought I had found the "Holy Grail" of sleep aids, since nothing had ever worked before. However, after about six months, the effects seemed to wane slightly. A couple of months ago, I began to have intermitten full-on panic attacks. At first, I thought it was stress from the holidays. But the panic attics continued and grew worse in January, and I began sleeping less. I'm beginning to fear that my body is becoming immune to the drug, and that the effects are changing from a positive sleep aid to a negative anxiety inducer. I mean, even trivial things were starting to just FREAK ME OUT, such as the thought of needing to affix the 2008 stickers to my automobile license plates or refilling my pets' food bowls. I tried going off it a couple of nights, but I flat-out could NOT sleep. I'm giving it a few more days, and then I'm calling the sleep clinic and asking to try something new. I would love to hear from anyone else who has experienced these symptoms. M 45 9 months
1/30/2008
Email
 4  Bipolar 2 crave carbs, pancakes,cookies cakes,but on 20lbs trying to eat the wright foods now after 9 months still trying to find the wright dose around 200-300 mgs a day M 49 9 months
3/1/2008
 3  Bi Polar 1 drowsiness, cognitive fog I think it helps but I DON'T LIKE IT M 62 9 months
75mg 1X day
8/9/2011
 3  rest symptoms after psychosis I take 100mg morning, 100mg night which is considered a very low dose here.(they only prescirbes it for psychosis and bipolar) Very rapid heart rate after each dose, must lay down. Dizziness, very weak and strange feeling in my arms and legs when i wake up. Weight gain! 52->65kg in one month. High blood sugar. jerks in arms and legs. very hard to explain depressive feelings in body. This med has helped a bit with my very svere anixety and my over-sensitve senses. It also helped me come off years use of benzo(the worst drugs that exist!) and sleep pills (not without a very hard fight though). I thought they were ok for me, but now they have caused high blood sugar and the rapid heart problems seems to get worse every month. I have started to taper and prays it will turn out okey. I feel i cannot trust drug companies anymore. In my country they write that most of the side effects applys to 0.1%-10% when they apparently are lot mor common!! M 27 9 months
9/24/2006
 2  bipolar? Anxiety? unsure melting sensation in thigh muscles, dry mouth, constipation, forgetfullness, crawling sensation on my skin and back pain All new to me. Never had a problem pre seroquel that could not be accounted for Withdrew because of physical and some alertness effects: -weight gain, pain, level of alertness and only added problems compared to previously. Mostly - crawling skin sensation in ears, urinary dysfunction( green foul smelling urine and very frequent), transient abdominal discomfort(severe- about 7/10 compared to gall bladder attack), Withdrawl - 2-4 weeks - occasional insomnia(New even compared to pre seroquel), intermittent severe sweating(new), cronic headaches(new), persistent deep back pain, abdominal discomfort and pain. 6 weeks - Intermittent stabbing ear pain only - crawly feeling skin and ear gone. Sleeping through nights intermittently. No melting muscles. Urinary function still not OK(underlying pathology?), GIT signs still not OK(underlying pathology?) Mind space now much better. F 47 9 months
50 1X day
7/18/2013
Email
 2  mood disorder I had what first started as occasional and then became daily occurances of hypotension. My BP would drop from 120/80 to less than 80/60 in a heartbeat. It would take me 3 to 4 hours for my body and the blood pressure to recover. My Dr. has taken me off of it. Not very good for the 200 mg 2 X daily, combined with 2 other seizure meds, UGH! I was very zombie like, although I certainly had an even mood. We were never quite sure this is what I needed. I feel better off of this. F 43 9 months
6/22/2005
 2  anxiety insomnia HUGE WEIGHT GAIN. I am weaning off of it. I was at a loss as to why gaining so much weight. I also get heart palpitations. Was put on 100 mg 3 times a day for anxiety. Big mistake. I now take 25to 50mgs a night to sleep. No energy the next day and I only sleep around 4-5 hours. Not worth it. I am weaning off all drugs. I imagine in the next day or two I will totally stop seroquel. Wish I never tried it. Never had the slightest weight problem before. Heart pounding and skipping beats. Can see my heart beat in my chest. Jumpy legs and little interest in doing anything. I feel my energy level returning and my desire to do things. Was given it after ex husband abandoned us. I care for our 4 year old daughter with DS. I will try and report back if weight changes with not taking seroquel. I am not expecting major changes but gradual decreases as I hope my metabolism returns to normal. I eat very healthfully. F 44 9 months
5/23/2007
Email
 2  bipolar mania , major insomnia lack of motivation, extreme depression, headaches, hypotension, increased pulse, dizziness, weight gain, dry mouth, constipation, personality change, puffy gums, no interest in activities other than sleeping. I would love to know how people sleep after having huge insomnia before seroquel as it is the most potent sleep inducer known to mankind. F 40 9 months
7/7/2007
 2  Severe Bipolar WEIGHT GAIN (20+ lbs)lethargy, zombie like feeling, dependance on it to sleep, shaking, visual problems that slowly went away, strange paralysis feeling if i try to stay awake for long after taking it at bedtime. Hair loss and poor overall mood. Being eating disordered as well as bipolar relly killed me with this drug because within 5 months I had gained a ton of weight and my self esteem hit the floor. I was told by my doctors that I wouldnt gain weight- they lied. I started taking this in the hospital and it helped right away but now I'm trying to get off it as soon as I can. My dose is currently 600mg, I also take paxil (37mg) and lithium (900mg) but nothing is as bad as the seroquel. F 19 9 months
4/14/2005
 1  depression horrible. wrecked my life. ruined my looks my physical health robbed me of family and friends....starting to ruin marrage. people treat me like I weirdo drug addict. i use to be beautuful successful and fun. Now ugly hiding out no emotions. Don't touch this drug. F 59 9 months
1/13/2018
 1  Insomnia, PTSD, DID Horrific nightmares, extreme panic, flashbacks increased in severity and length, wake up drenched in sweat, body would suddenly jerk, zombie feeling, no sex drive, intense weight gain then lost appetite completely, severe depression, tingling and numbness These drug terrifies me now. I stopped taking it a week ago and my mind is clearer already. My doctor said it would help me sleep and instead I ended up in a world where I didn't know what was real or not. Then started drinking heavily to deal with the nightmares and anxiety, would rather pass out then be in any state to dream. Now I am not taking anything except Lexapro, no over the counter, no alcohol. I was in hell when I was on that drug and wanted to die. Learning how to sleep in a more natural way. Lacked desire to do anything. Would have these hideous experiences while only taking 50mg. I am so glad I found this website because it let me know that I am not alone in my reactions, I am not losing my mind. After reading this website, I took one 50gm dose and nothing else and that night, horrific panic attack, hallucinations both visual and aural, intense fear when I finally feel asleep a nightmare in which I thought I wold scream forever and woke drenched in sweat. F 49 9 months
8/18/2009
 1  Bipolar disorder I became a zombie, extremely suicidal, irritability, headaches, severe depression, increased anxiety, increased paranoia I wish my doctor would take me off of it, I hate the drug. It's not worth taking, it will screw you up more than it will help you. F 15 9 months
500mg
8/1/2016
 1  Skitzo Affective Disorder TIRED ALWAYS wanted sleep even though i would have over 15 hrs!! LOST my personality was a ZOMBIE, VERY OVER WEIGHT, , DRY MOUTH , SLURRED SPEECH, couldnt have a conversation. Self medicated n nearly over dosed. When i first starting taking seroquel, i became very paranoid thinking i was goin to die. Eventually started taking way to much over 900mg a day n had to quit my job coz i was too tired n too hungrey to work . One thing i remember about seroquel was my life revolved around food and sleep. i would take the tablet , eat but still be starving even though i ate heaps, fall asleep for way to long , then do it all again . I had no life SEROQUEL took over my life.... stopped COLD TURKEY , was sick in bed for over two weeks, never forgot how much pain n effort it was but was well worth it , SEROQUEL is addictive you crave that feeling it gives u even after you stop taking it.I have no idea y doctors prescribe this medicine when it only creates another problem. F 23 9 months
1/13/2010
 5  skitzophrenia puts me to sleep hard to get out of bed leveled me out completely no more extremes no more halucinations or auditory halucinations i got to keep my job because of this drug M 21 10 months
50 mg 1X day
10/19/2013
 5  Bipolar I feel groggy in the morning...nothing a couple of strong cups of coffee can't fix. Light headed when getting up from a kneeling/squatting position (affects blood pressure). Main concern is the knocked out feeling at night...I'm afraid I'll sleep through a tornado! No weight gain...possible weight loss? I'm not sure since I also quit drinking large amounts of alcohol. Dry mouth right after I take it and restless legs occasionally. Seroquel has definitely helped with racing thoughts, irritability and anger. I'm on Cipralex for depression, but I believe the Seroquel is giving a boost in this area as well. If I miss a dose, I can feel the negative emotions quite quickly. I am able to organize my thoughts and doings much better than before the meds. I must add that I was on 25 mg and slowly progressed to 400 mg. I still didn't feel that it wasn't quite right yet, so now I'm up to 500 mg. Along with 200 mg of Cipralex, I'm coping much better. F 42 10 months
9/15/2008
 5  Schizoaffective Disorder; Insomnia Worsening essential myoclonus and myoclonic sleep jerking I take 800mg every night. This drug saved me from the very rapid and abrupt adulthood onset of uncontrollable mood swings and hallucinations. It is the reason I am alive today. However, it doesn't work for everyone. I know plenty of people who take like 25mg and then totally lose touch with reality it for 48 hours. Give it a chance, but be wary. M 20 10 months
4/11/2009
 5  ocd (obsessions only), Asperger's weight-gain of 45lbs. from low of 105lbs.(during my ruminative depression) Previous normal weight ranged from 135 to 155lbs over the years on a 5'5" frame. Sleepiness when waking up; some groginess over the morning, which is combatted with coffee where I presently work. Cholesterol went from 160 two years ago to 239 at present: was that from weight gain or the seroquel itself? After trying lamictal (& other antipsychotics for my obsessions, over the years), I must say that seroquel, at 200mg at bedtime, has virtually eliminated my ruminative depression over the loss of my last job, as well as other obsessions. In fact, I haven't had to go to any OCD support group meetings since I have been on seroquel. I'm still somewhat slow, but I'm less distracted, and not sad. I also take WellbutrinXL(300mg), and EffexorXR(75mg) in the AM. P.S: the prozac I had been on for 10yrs since my husband died finally "pooped out", and it never did help me stop obsessing as well as the Seroquel has. F 57 10 months
11/6/2006
 5  bipolar Extreme drowsiness when first prescribed. After it gets into your system, you will feel ok. Take only when you can devote sleep time to it though. i.e don't take it, and then go driving afterward. It eventually doesn't knock you out right off the bat, but there is weight gain. Workout and watch what you eat. M 25 10 months
4/19/2007
 4  bipolar disorder Sedation and confusion 30 - 60 minutes after ingestion, difficulty waking up, extreme confusion after waking up, forgetfulness At first I thought this was a wonder drug - after suffering from a nervous breakdown it made life bearable, 'took the edge off', helped me sleep, helped me get through the day, gave me a lot of mental clarity that I had been missing. I started on 100mg, taking 25 throughout the day as needed, ended up at 600mg (slept faaar too much), came back down to 400mg about 8 weeks ago and have slowly had to come down to 75 - 150mg as needed since then as I was having major problems with sedation, completely oversleeping (missing work etc.), being unable to be woken by others, etc. I have difficulty sleeping without it, and if for some reason I don't take a dose I get hypomanic the next day. I find it helps me heaps, and I haven't had the issues with weight gain that others seem to have had (in fact my weight has dropped drastically), but it's become obvious to me that over time it has completely screwed my memory - I forget words, names of people I have known for years, my own phone number, w F 25 10 months
6/24/2007

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