SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  bi-polar disorder, chronic insomnia i sleep walk and sleep eat, i get temporary amnesia and my memory is effected but the positives of being guaranteed a good nights sleep well over comes the side effects and i am careful to keep food in the house that is healthy, andi exercise, so a happy medium has been found and restored a great deal of sanity to my life. i've been watching the shows about ambien and if there was a friviilous lawsuit of the year, those people are class examples. they do NOT now how a chronic insomniac lives and the side effects are MILD compared to what we have faced and will face each night in that insomniac prison.......... F 45 4 years
3/26/2006
 5  LOTS OF REASONS Not Too sure on too medications and am happy to and extent....mostly dry mouth, needing sleep, muscle twitches, MAJOR WEIGHT GAIN, breathing is hard good drug like i say it might be this one or the wellbrutrin but I have no more depression i think...not sure..at least dont want to die...and i am not angry anymore so thats good, although occasionly i would like to get mad to kick some bullies ass! M 16 4 years
1/16/2006
 5  bipolar Major over-eating at 400MG 3 years ago. I gained 30 pounds! If I drink any amount of alcohol I have leg twitches at bedtime. I was over medicated at 400 MG. I'm now on 150MG and it has been wonderful for me. I have lost all of the weight and no longer have cravings. I am not fuzzy during the day and sleep great at night. The leg twitches are very irritating and I have found that alcohol causes this effect with me. I no longer drink. If you are having these type of side effects or other kind, talk to your doc because I think it is a good drug but docs can easily over medicate you. I went off the medicine completely for 6 months and saw how much I benefited from the drug. F 36 4 years
2/2/2009
 5  Bipolar disorder I guess 10 pounds weight gain ,and sleeping 9 hours Its helping . F 31 4 years
50 1X day
5/25/2020
 5  Bipolar II increased appetite, some weight gain, sweating I take 100mg at night and an additional 25mg+ prn. It helps me sleep. It controls my agitation. It is the only intervention for obsessive, tormenting, repetitive thoughts that has worked. It is an absolute life saver in that regard. The postitive effects far outweigh any side effects. I have no doubt that this drug has kept me out of hospital for the last three and a half years post-ECT. F 40 4 years
7/14/2009
Email
 5  Bipolar Weight gain,lethargy Started on 300mg per day then gradually reduced to 25 mg taken at night.Can increase dosage when needed which gives almost immediate relief from symptoms.I do find I have less energy than I used to but that is better than a mind and body on overdrive.Seroquel has made me calmer but you have to compliment it with life style changes.No drinking alcohol,caffeine,late nights and try to avoid any trigger situations.My kids call it my magic pills and I will continue to take them for life. F 46 4 years
25mg
5/18/2016
 4  Insomnia/Racing Thoughts/OCD I take this because my mind cannot stop the chatter at night. I have taken 100 mg one hour before bed and it has worked well for four years without having to increase the dose. I do take Restoril 30 mg when needed, which is rare and usually due to occasional back pain. The sedation wears off by the time I wake up. F 45 4 years
11/11/2009
 4  Mood instability, anxiety Drowsiness, lack of motivation, weight gain Helped my mood to stabilise and helped anxiety. Helped with sleep as I would have highly disturbing vivid nightmares. Too afraid to come off so that's why I have been on so long. Currently on day 5 without it, all good apart from intense itching of my skin. Going to ride it out M 33 4 years
25-150mg 1X day
7/29/2020
 4  Anxiety causing insomnia None. One concern I have had anyone experienced hair thinning with this drug? Not sure it has been a side effect or it's just me. F 69 4 years
25 mg 1X day
10/21/2020
Email
 4  bi-polar I sleep much better but I don't like some of the side effects the worst of which is the weight gain. I also experience dry mouth and my sinus's get blocked up, usually about an hr. after taking the medication. My mood has been much better since taking this medication. I am on a fairly high dose (600 mg.at bedtime) and I have recently had my dose reduced which has helped with the stuffy nose and dry mouth. Over all I believe the benefits outweigh the side effects. M 51 4 years
11/23/2008
 4  PTSD/BPD Dangerously low blood pressure (70/40), severe tachycardia (up to 150 bpm even while lying down). Severe gastrointestinal problems, namely severe constipation, which required additional medications. It basically shut my bowels down. Severe sedation; often overslept and was late for work. Would fall unconscious after taking the drug. Could not be woke up after taking the drug. Slurring of speech, amnesia, blackouts, short term memory loss, fatigue; some weight gain, but I fought this off with a rigid diet and a highly disciplined workout regimen. Some binge eating (which I didn't always remember). Difficulty concentrating. It was a huge improvement over the crap they had me on. At first it helped me. I was having severe PTSD symptoms and Seroquel knocked me out and helped me sleep, eliminated recurring nightmares, made the anxiety tolerable, and reduced the disassociation; for awhile, Seroquel was a life saver. I was taking up to 450mg. Then, it became a nightmare. The racing heart was terrifying. ANd one night my heart stopped for a couple minutes. No pulse. Then my blood pressure began to crash regularly. My internist told me I had to reduce my Seroquel or it would kill me. Since then (summer 2006) I have been gradually cutting it back. Next, I was diagnosed with tachycardia, after having severe shortness of breath and landing in the ER twice because I could not breath. Now I take a beta blocker to control my heart rate. The cardiologist says there is no medical reason for the tachycardia. The beta blocker has done more for my anxiety and PTSD symptomps (particularly the adrenalin rush, flight or figh F 33 4 years
1/14/2009
 4  Bipolar/Impluse Control Disorder EXTREME grogginess, weight gain. However, it significantly slowed down my racing thoughts. But my biggest positive is that it gives me a quick "pause" to think before I act violently which I had so much trouble doing before I started taking it. When I first took Seroquel 4 years ago in the hospital, it nearly knocked me unconscious to the floor. I was taking 200mg at bedtime. I couldn't keep my head up. Usually happens an hour after taking it. The side effect feels as if my brain has a brick on top of it, and no matter how hard I TRY to think positively, there is a negative fog that clouds every thought I have. Usually all of this goes away after 2-3 hours, which is why I can only take it before bedtime. Recently, I relapsed and ended up back in the hospital because I stopped taking my meds. I now take smaller 50mg doses of Seroquel at morning and night. I do notice that the negative side-effect is not as severe. M 24 4 years
1/11/2009
 4  biplar disorder 1 I am from saudi arabia . seroquel was new here and i read about it and decided to try it > I experienced through manageable weight gain . sleepiness (6-9) hrs , red conjuctiva , immediate drowsiness after taking the current dose 500 mg once at night , feeling anxiety and dysphoric after the dose that got releived by klonopin 0.5 mg all together , sleeping like an infant , oversalivation during sleep that gone away after several months , rarely slurred speech that doesnt bother me . This magic drug stabilize me throgh the day like a Bible .. make it so bright for me not to slip ..raised my social status , improved my cognitive functions and increase my anger thresold dramatically ...finally it gave me the fourth dimension of thinking that i had been missing all my life as a messy untreated undiagnosed BP !now I got it why i had been called mad most of my previous time ! M 34 4 years
3/18/2008
 4  bipolar extreme sleepiness, hunger, forgetfulness, I take 125mg at night, would not be able to sleep otherwise. I have a 25mg prn but cannot take it because I will eat uncontrolably. It makes me forget and feel dumb if taken during the day, at night can only handle 100 or 125 mg without being forgetful the next day. F 26 4 years
5/10/2007
 4  Bi-Polar Disorder Tremendous Weight Gain, Lack of energy Seroquel has done wonders for my bi-polar disorder, but I have gained 100lbs in 4 years time. I was 150lbs when starting and am now 247lbs. This is a salt-based medicine which leads to the weight gain, love the drug hate the side effects. I basically have to choose between being sick or crazy. For now Im living with the excess weight gain, but unfortunately my body cannot keep taking such a beating. Great drug, but please do not use it for long term purposes you will become hooked and the side effects will take a major toll on your health. M 26 4 years
300mg 1X day
4/23/2011
 4  schizophrenia it makes me sleep, it can make mornings "drawn out" in terms of grogginess, irritability and non-motivation. sex drive is stifled which i don't mind. appetite appears normal with my dosage. Without this drug I would quickly drift back into a paranoic, thought riddled chaos that makes movement outside impossible. The main drawback I think is the dampened mental and creative sharpness that I'm not completely aware of, but it is regularly suggested to me by the pitying treatment I recieve from normal people. Thankfully I'm too numb to care THAT much about it. M 40 4 years
100mg 1X day
1/9/2011
Email
 4  bipolar/some psychosis My major problem was not sleeping which this has really helped. Takes a while to get going most mornings but not sleeping too much . Some weight gain and still havve some anxiety issues. Overall has helped. M 56 4 years
300 mg.
4/13/2013
 4  Severe Anxiety/Worry, Depr,Paranoia Extreme drowsiness, lack of energy/motivation each day, sleep 9-12hrs+ each night, over eating at night after take pill; weight gain. Dry mouth for about the first 6mos (give or take). After taking other medications with what I considered during that time more severe, I settled with Seroquel. Other medications made me suicidal, I could not think clearly like I was "drugged up" and I once lost my feeling "down there" for over a week which was horrifying because the doctor said it may or may not be permanent damage!! Fortunately I regained 'feeling' down there after a week or so. With those side effects, I was about to give up until I got a new doc who recommended Seroquel. I started off taking 50mg each night and I spoke with my doc about the extreme sedating effect and lack of energy so they dropped it to 25mg. DON'T ask me how some of these other individuals managed to function on 100-800mg each day?! That is absurd! I would be a bed ridden zombie if that was the dosage for me! I can't believe such a high dose is given for first timers anyways. As you can see from most of these reviews, that this is a common dose and all the complaints are similar! How can you not have severe health issues with such a high dose of anything in this world! ...even vitamins and healthy foods should be consumed in moderation! So you cannot base your decision solely on those who have taken such high doses since our bodies are quite different. I am quite sensitive to many things including lactose, gluten, decaf/reg coffee (severe anxiety), etc. So 25-50mg for me is a bit too much. I love Seroquel in that it has eliminated my anxiety, depression and paranoia w F 31 4 years
25mg 1X day
5/6/2011
Email
 3  sleep aid for bipolar disorder initially very drowsy and "drunk" feeling. would have to go to bed immediately upon taking it. If I take the dose a few hours late, I get nauseous. If I miss a dose, I toss and turn in my sleep and may get hyper. The next day, I feel awful: depressed, irritable, sometimes suicidal thoughts, revved up energy Overall, Seroquel has worked well. Initially, it was a wonder drug for quieting my racing thoughts and improving my concentration. It also helped with mild paranoia. I have been lucky to not have any weight gain. F 31 4 years
50mg 1X day
4/26/2011
 3  bipolar 2 (for anxiety side), sleep grogginess waking up, some short-term memory loss ( I think) After years of not being able to sleep due to anxiety, my doctor started me on a very low dose of seroquel - 25mg. She increased my dose slowly and tried to get to 200mg, but it made me like a zombie. I came back down to 50 mg and have been there since. (I'm very sensitive to medications.) 75% of the time, I'm asleep within 10 minutes of taking it, and I sleep through the night. But if I don't get a full 8 hours of sleep, I can be very groggy the next day and that fuels my anxiety. It's very important to be able to get a full night's sleep when on this medication. I'm taking this in combination with Lamictal 200mg. M 40 4 years
50 1X day
12/11/2010

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