SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  anxiety and insomnia weight gain of 50+ pounds, severe dependency, apathy, decreased sex drive, zombie throughout the day, irritability I am warning anyone out there that once you get on Seroquil, you are selling your soul! I have withdrawn from MANY drugs, and this one BY FAR has the most dependency of anything that I've ever taken! If you want ANY quality of life at all, run in the other direction...anything is better than being dependent on Seroquil! I am currently decreasing the dose on my own until I am off of this drug....I want my life back! I was prescribed 600 mg at night, and looking back on my history with this drug, I have noticed that EVERYTHING I hate about my life was a direct result of the side effects that I have from Seroquil! Sure, you may feel better after 7 days, even 7 months, but take it from me, the long-term effects are not worth it...and I pray they are REVERSIBLE! F 35 2 years
11/26/2007
 2  insomnia weight gain,dry mouth,morning hangover,trouble falling asleep,having to increase the dose after awhile. i started the med at 25mg,and slowly inched my way up to 300 mg. I stayed there for a year,finally couldnt take the morning hangovers,soo got it lowered back down to 100mg,but I found that I couldnt sleep without taking atarax along with the seroquel. At 300 mg i had excesive munchies,and dry mouth and eyes. At 100 mg the only thing is that I cant sleep. soo anyone out there thinking of raising the dose to 300 mg or more,DONT!! F 29 2 years
1/22/2009
 2  bipolar extremely tired, take at night, sleep 10-12 hours, short term memory loss M 57 2 years
5/24/2008
 2  Bipolar 2/OCD/Anxiety Life revolves around sleep (either knocked out cold or awake all night), groggy and sedated, rapid extreme weight gain, increased appetite, diffuculty finding words, slurred speech I've been on this med for 2 years (started on 12.5mg, now at 200mg SL) At the dose I am at now, I sleep better for the most part, I have not have a manic episode for the whole time I have been on it, and recently my anxiety has been a lot better. I have tried to tolerate it because it seems to work, but I can't tolerate the weight gain and very concerned about the slurred speech. F 29 2 years
200mg 1X day
4/15/2010
 2  Bipolar I Pisa Syndrome(please google) *weight gain* Seroquel is a very effective drug for me. I am now getting off Seroquel. It's the weight gain thing. If your genes are set up for you to gain weight on this, you will, probably very quickly. I've had enough and I usually put up with most side effects. At 60, putting on 40 pounds is dangerous. Really at any age. Hopefully Lithium and Lamictal will keep me afloat because I'm not gaining another pound on this. M 60 2 years
300 mg 1X day
4/1/2013
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 2  sleep No side-effects. Withdrawal causes problems. Switch to zyprexa 20mg and cold turkey it. Alternatively increase seroquel to 600mg and stop it but doses above 400mg make seroquel work like mild SNRI and are not long-term. Never start antipsychotics voluntarily. Always use neurologists and sleeping pills. M 32 2 years
400 1X day
5/16/2013
 2  Depression/Anxiety Dry mouth, forgetfulness, clumsiness, and intense sleepiness were the only side effects at first. Over time the sleepiness (which I needed to get to sleep at night) dissipated, and coupled with my anxiety would make bedtime like a bad trip. Everything looks weird, makes me panicky. It never did seem to help my depression, though it did help me sleep at first. The dose was constantly upped after the effects would wane. The cons outweigh the pros, I would not recommend this. Maybe it would work better for someone else but after the first few months the positive effects went away and now I just take it because my doctor tells me to. F 25 2 years
400MG 1X day
8/13/2013
 2  bipolar rapid cycling/mixed episode I didn't ascribe the weight gain (10 lbs) to seroquel until I read this board. Dizziness, physical imbalance, crankiness, sleep too much or wake up groggy and can't go back to sleep. Searching/struggling for words on a consistent basis (I have a very high IQ and teach as well as work in customer service) and this makes me feel like a DOPE. Pdoc says, "oh, that happens to EVERYONE when they get older." OK, I am FORTY two, not NINETY two... Brain moves slowly. Motor movement is affected, I am sometimes klutzy. I have had two car accidents (not my fault) and several close calls, ALL on the RIGHT side. Coincidence?? My vision is sometimes blurred. I used to be 20/10, now 20/20. Some days I'm fine, probably about 60% of the time I feel functional and able to perform my job and interact with others at optimal level. Currently taking 3 20 mg tabs of seroquel at night (used to sleep with 2, but now even 3 doesn't do it). Now I can't fall asleep at night, wake up during night, I was prescribed seroquel for insomnia by a doctor who would nod, say "mm hm", and write the same prescriptions without regard for my comments. I wanted a happy sleepy pill, he gives me an anti-psychotic. Went a new office, GREAT therapist, new pdoc. More attentive than the "mm hm" guy, makes you think he is listening, then prescribes how he wants to anyway. I asked to be taken off seroquel, explain side effects. So pdoc decides seroquel will be the BASE of my treatment! Sick of being treated like a child, bringing my fiance next time. Pdoc says it hasn't been proven that seroquel causes diabetes. Then says, "if you take good care of yourself, you will have to take some pills (FOR DIABETES)in your 60s. If you don't,you will be taking pills in your 40s & 50s" So he says it doesn't cause diabetes, then tells me it WILL, no matter WHAT I do? Also, on last seroquel scrip pdoc wrote 2 a day, have been on 3 for almost a year. Had to call pharmacy, have him w F 42 2 years
3/20/2006
 2  Bipolar 2/cyclothmania weight gain 40 lbs, blurred vision, stuffy nose, fatigue, elevated blood sugar levels I was receiving poor medical care and was actually on 800mg for a whiel and was a mess. I am seroquel free now and feel great. I believe it can be used once in a while for a bout of insomnia but I believe because the drug is so new, the side effects are not worth the benefits. F 32 2 years
11/14/2006
 1  Depression, OCD, anxiety Weight gain! Lethargic all day even though took only at night (100mg). Dry mouth. Chronic constipation with severe cramping. Trouble concentrating and focusing. When missing a dose, terrible itching all over. Stopping this medication is also a nightmare! Even with tapering off, I've had heart-jumping-out-of-your-chest panic, extreme anxiety and agitation, fainting, reslessness, bad headache, flu-like symptoms. Although this SEEMED to help me when I first started it, it is hell now! Yes, it helps with sleep but as a higher dose was needed as my toleration to it increased, it has caused nothing but problems. I have a small child and run a small business and the zombie feeling is intolerable. I found I want to sleep all the time. When I want to do something, I don't have the energy to finish it or am so exhausted that I just want to crash. Constipation major problem too. Have had IBS for many years but diahhrea was always main symptom and I became problem-free for a long time. With this, constipation became such a problem, IBS is back and now I'm on even more medication to manage that and afraid to eat anything. I'm tapering off of this now (from 100mg to 50 to 25 now and then no more!). The side affects from tapering are so bad I have had to increase my use of xanax just to manage the panic and anxiety until I'm finally off this crap. I've been on a littany of meds for the many years F 43 2 years
1/7/2007
 1  Bipolar nos Side effects were weight gain rapid heart beat ,pressure pain on my chest , tired from the time I woke up; bloating and swelling of the stomach and problems with my Bowles.also developed a peptic ulcer and type 2 diabetes. just came off seroquel last week doing much better, this medication is horrible ruined my life for 2 yrs doctor would not change my medication so I changed doctors to someone who saw what the side effects were doing to me and now I am able to live my life again. M 48 2 years
300mg
12/15/2012
 1  anxiety, depression, insomnia Weight gain (35 pounds), unusual and sometimes disturbing dreams I was prescribed this medication by a psychiatrist at an outpatient program I was in for one day. This doctor did not explain to me what the drug was for or what the side effects were, and it was not until I started seeing a more responsible psychiatrist that I learned about this drug. It was a highly innappropriate drug to be prescribed for my symptoms, and the side effects (weight gain in the short term, and tardive dyskinesia in the long term) were absolutely not worth it for me, and not for most people. It did let me sleep, which was why I continued taking it for so long and even started again after quitting. It didn't help my anxiety or depression. F 24 2 years
1/9/2006
 1  Bipolar Disorder I have been on seroquel for 2 yrs,it always worked great, always tired but that was ok,seeing what the alternative was.....Crazy and no sleep, but now i sleep all day at least want and need 16-18 per day,I am about to lose my job due to sleeping thru alarm clocks,phone calls,etc.. I am hoping to see my Doctor tomm, to get me off this drug..THIS DRUG IS SOOOOOOOO BAD FOR AN EVERYDAY PERSON WHO NEEDS TO MAKE A LIVING!!!!!!!!!! I am really scared my Dr will not want to take me off this drug. But all i know is that i cant continue on this way, i fel more upset everyday because i cant wake up.. IM AFRAID TO GO TO SLEEP BECAUSE WHAT IF I CANT WAKE UP IN TIME FOR WORK???? Just walking to the fridge to eat everything cuz this is what happens is so tiring for me... I would rather be manic and never sleep than never waking up on time for work..... AMY F 34 2 years
10/11/2007
 1  Bi-polar I now have diabetes, with high blood sugar, no family history. I was not told of the increase BS issues and the questions surrounding this med, otherwise I would have never taken it. That said, It did a good job getting me to sleep at night. Don't know if it's helped anything else though. M 33 2 years
50 1X day
8/9/2010
 1  wierd dreamlike states and insomnia For 2 years mostly nothing. After discontinuation from 400mg/night gradually to 0 mg/night and back up to 400mg/night and then difficulty following exact dosages: tinnitus, memory and thinking problems. NOT A SLEEP MEDICATION USE VERY LOW DOSE OF DOXEPIN FOR SLEEP (<5mg). I was given Seroquel after I took oxamin+alcohol (accident/panic) and had wierd dreamlike state and voices when trying to get sleep and MILD insomnia (Nothing during to day). I took it like a fool. Because I could sleep (it was just a difficult) I should have went to a neurologist specialized in sleep or just wait for GABA receptors to slowly heal. (Maybe using antihistamine for a month or something to get better sleep). M 30 2 years
400 1X day
1/3/2011
 1  Depression Seroquel caused severe restlessness to the point it felt like my skin was being torn off, emotional liability, unusual behavior, nightmares and horridly painful muscle spasms. I had to put rolled up wash clothes in my hands at night so my fingers wouldn't curl up into my palm.I jerked so badly I slept in an upright recliner. It make me so sedated I was unaware of what was happening. One night I ended up in the Emergency Room with Seroquel-induced Pancreatitis/Diabetes (this is a documented side effect). I spent 3 months in the hospital with a tube down my nose.A physician diagnosed me with the worse case of drug toxicity he'd ever seen so I went off the Seroquel. Make sure someone who really knows you can monitor your behavior when on Seroquel. A doctor who only prescribes this may NOT notice how it has caused you to became erratic (Iatrogenic Illness).Seroquel is a major anti-psychotic and very very powerful.Consider NOT taking this drug at all. M 52 2 years
300mg 1X day
3/18/2011
 1  Severe Depression and Anxiety MAJOR WEIGHT GAIN. I wasn't overweight when I started taking Seroquel, and never had been, but it put 100 POUNDS on me within 12-18 months! I'm not kidding. The 100 pound weight gain from Seroquel has been devastating to me. I want to hide in my house so that people won't see me. It has caused me to have GERD (gastro-esophogeal reflux disease) where I've had to have two operations where they've put a camera and a scope down my throat. Acid reflux was causing erosions in my esophagus (all because of the weight gain due to the Seroquel). And then I developed severe sleep apnea, once again due to the horrific weight gain due to the Seroquel. I had two polysomnographies and I would stop breathing 1,000 times a night. I now have to breathe with a CPAP machine forcing air down my airway at night so that I don't stop breathing or have a heart attack. I can barely move now-- getting up and down from bed or a chair and even walking a few steps is very difficult. I can't clip my own toenails or shave my legs or put on my shoes because of the terrible weight gain due to the Seroquel. I live in fear of developing heart disease and diabetes. F 41 2 years
1/31/2008
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 1  mood stabilizer, bipolar disorder very sick when i didnt take it..it made me light headed...but it made me feel good...but i didnt like the effects it had on me when i didnt take it...it felt like i was withdrawin from heroin dont take it F 17 2 years
1/18/2005
 1  depression severe anxiety insomnia grogy lithagic, gained 30lbs, couldn't remember name,s words etc zombie like the next day, would catch myself not inhaling or exhaling (too relaxed), I still have blurry eyesight occasionally, had hard time reading other peoples experiences with this deadly drug. I started to feel like my organs were shutting down and I was swelling up. Developed a mass on my adrenal gland luckily my cortisol and hormone levels were normal. They thought I had hypothyroidism and developed nodules on my thyroid luckily no cancer and no hypothyroidim.. I now have to have both checked every 6mos to a year to make sure mass and nodules don't get to 4cc or they will have to operate. I was so knocked out at night didn't realize I was having acid reflux developed 8ccm hiatal hernia with a rare Cameron bleeding ulcer. Lost half my red blood cells 5 count (11 is normal)) had three blood transfusions and was in the hospital for a week I was acute critical and was severly anemic had to take large dosage of iron got my red blood cell count to 10. I am having sergury Monday for hiatal hernia repair and hopefully the Cameron ulcer will get better. I quit taking seroquel cold turkey the first night off of it my mind was racing and couldn't sleep at all sounded like hundreds of voices were talking at once it was horrible. Eventually after 3days I could sleep waking up about every 2 or 3 hrs. My doctor said that I was not suppose to go off it cold turkey and I was lucky I didn't have seizures. Besides side effects listed above I feel much better since I quit that deadly drug. My pysch was angry I went off Seroquel and told me that this will not end well????? Well she was wrong it has ended well , she prescribed me ambien 10mg and I sleep at night and wake up ref F 61 2 years
300 mg 1X day
12/6/2017
 1  Bipolar I Weight gain +90lbs in combination with Risperdal and Zyprexan. Can't wake up in the morning. I was a med school student going to be a doctor. This medicine ruined my life. M 20 2 years
7/2/2007

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