SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Bipolar I becam a cookie monster, gain 30 pounds, still struggling to loose the weight after switching to lamictal a year and change ago. I was a real zombie after the pill kicked in, Horrible!!!!!!!! M 42 2 years
7/22/2007
 1  I had a few psychotic episodes My main complaint is a tremendous weight gain of 25 pounds in 2 years. I take so much other stuff for depression, that I can't separate out the other symptoms. I desperately want to get off Seroquel and tried tapering it, but tapering threw me into even worse depression, so I had to go back on it. How can I stop using it? I think it works for my depression, but I'm not positive, since I also take Prozac, Antenolol, and trazodone. I need a safe way to test out which meds are working for me and which I don't need. F 59 2 years
12/12/2004
 1  MDD, OCD, anxiety Went to my psychiatrist today and he confirmed side affects (weight gain, fatigue, lethargy) I described below WERE related to Seroquel. Off the medication for one day now after dosing-down for almost 2 weeks (100mg to 50 to 25). I posted the comment just before this. Although getting off this medicine has been hard, I'm glad I'm doing it. My doctor said I should have it out of my system by next week. Right now, we're sticking with the Cymbalta at same dose until we see how being off Seroquel for awhile does. I've managed the withdrawal side affects with xanax to help curb panic and anxiety and taken Benadryl to help with the itchiness. Still, stopping this medication is NOT PLEASANT! During the first couple of days of dosing down, I thought I needed to be in the psych ward again! F 43 2 years
1/9/2007
 1  Bipolar Disorder Seroquel can cause tardive dyskinesia. I was diagnosed with it at 19. It's an unbearable, potentially permanent and disfiguring neurological disorder that destroys lives. I do not recommend it. F 19 2 years
500 MG
5/9/2015
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 1  sleep Weight gain, AM hangover, sugar/carb craving I was 105 in 2007 (thanks to topamax I was taking for another condition) and could eat anything I wanted). I was prescribed low doses of Seroquel in hospital, which didn't work. My idiot shrink bumped me up to 400mg per night about six months ago and decided to throw in 200mg of Seroquel XR for a better mood three month later. Before I knew it I had gained 20 pounds, which even the Topamax couldn't stop. Now I can't eat anything without gaining 5 pounds per day, and I'm not kidding about that. I'm due for my annual physical and I'm curious to see what my blood sugar/triglycerides/cholesterol/thyroid function is. I also crave milk at night. I'd crave soda if I had any. Oh, and recently my eyes are f****ing up on me. I am 45 also and don't need cataracts. I stopped taking all of that poison cold turkey and started taking over the counter sleep aids, since my ass doctor refuses to prescribe benzos. I'm not going to tell him I stopped the Seroquel because he thinks it's the do-all-be-all drug that will help everyone. I would like to know, though, how the hell long it'll take me to lose these damn 20 pounds. F 45 2 years
6/2/2009
 1  Dr presc for anxiety Couldnt walk vertigo uncontolled movements leg weighlessness feeling notbon ground I was seeing things in day angels looking from heaven F 2 years
850
8/3/2019
 4  Bipolar I Daytime sleepiness, sleeping for long periods of time (12-14 hours), difficulty getting out of bed, and occasional dizziness within 20-25 minutes after taking pill This drug has been weight-neutral for me. It works for me better than Ambien or Sonata to help me fall and stay asleep; however, once I swallow the pill, I can expect to be too sleepy to stay awake during a simple conversation. It took two years for me to work up to the point (at 50 mg.) where I can stay awake (and alert) for an hour and a half before going to bed. Before, it was 20-25 minutes. Occasionally, I'll forget things I do or say directly before going to sleep (usually parts of books I'm reading). Daytime sleepiness went away for me after two years, as well. F 32 2.3 years
4/25/2007
 5  bi-polar rapid mood swings wieght loss, sometimes hard to wake up in the morning. I am now taking 350mg at night and for the first time sice I was teenager I am sleeping 7-8 hrs a night. At higher lvls seroquel cleared my head and I could comprehend stuff much better than I could before. This drug actually has helped me lose wieght by stabilizing my mood swings, so I can focus and carry out an exercise program. The only time I have side-effects is when I drink, thats when I get the muscle spasms and zombie like feeling, but since seroquel stop me from going manic when I drink, I don't see any point in drinking at all. I guess I could say seroquel has helped me kick a very bad drinking problem. This is probably a result of its mood stablization properties, it keeps me from goin manic so I don't get the unbeiliable high I used too when I drank. M 30 2.5 years
5/26/2005
 5  bipolar II Wonderful sedative properties at 300mg at bedtime (just once a day). I get a full nights sleep (7-9 hours depending on my work scedule). The first few weeks of starting, I was fairly drowsy in the morning, but once I was on it for a month, the am drowsiness disappeared. For those of you who have bipolar depression, you already know how critical regular, restorative sleep is to keep our moods even and live a peaceful, prductive life. This medication has also been lifesaving in stabilizing my moods following 3 1/2 years of ineffective treatment with varying doses of depakote. Following a horrible hypomanic episode (with a subsequent potentially fatal depression)in spring of 2005, my psychiatrist tapered my off of depakote, transitioned me onto Lamictal, and added Seroquel at the some time. The Seroquel really seemed to be the ingredient that evened out my moods and reduced my accompanying anxiety and aggitation during that hypomanic spell. My family and co-workers have also noted a " This medication is very dose dependent, i.e., less may be more. I am taking 300mg at bedtime and we (my psychiatrist and I) titrated the dose up gradually (over 4 months) until I reached an effective level. Yes, weight gain can be an issue. I have gained about 12 pounds, BUT, have noticed that the eating tends to happen at night time, about 1 hour after taking my dose. I've found that if I simply take my dose no earlier than 30 minutes before turning out the lights, I avoid the typical onset of the "post- seroquel munchies" if I take it within 30 minutes of shutting off the lights. If I take it much earlier, (i.e. if I stay uup to read or watch tv), I will be in the kitchen snacking. I am not willing to go off seroquel for the weight gain issue since mine has been mild to moderate and this drug has been a miracle in managing my moods! :O) F 36 2.5 years
10/3/2007
 5  Bipolar I Disorder Weight gain, sleepiness, vivid dreams I consider it to be a life saving medication. F 35 2.5 years
100 MG 1X day
1/25/2012
 5  Bipolar 1 w/Psychosis Weight gain (120lb. In 2.5 years), tremors This medication was a lifesaver!!! I was lithium for 3 years before seroquel as well as other anti psychotic and anti depression drugs that made me extremely ill, this other drugs also made me feel useless and it bothered my ability to study, this was a major problem due to my college class schedule. M 26 2.5 years
3/25/2006
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 4  Anxiety & OCD Dry mouth, twitching, muscle spasms, gained 30 lbs, excessive sweating. Coming off of it I have experienced muscle aches, headaches, dizziness, lightheadedness and flu like symptoms... it's been 1 week since I have been off... and for the most part I am not experiencing the dizziness etc. I haven't lost weight yet. I have never gained so much weight in my life except through pregnancies! F 28 2.5 years
8/9/2006
 4  bipolar, ocd, anxiety sleepiness, dizziness I take 25 mg in the morning, which is enough to take the edge off my anxiety without making me groggy. At night I take 50 mg to let me sleep. I naturally sleep too long when I'm in a depressive state, and of course it doesn't help with that. Overall, I'd say it's worth it. They put me on 300 mg first, which I couldn't tolerate at all. Once we lowered the dosage, my side affects went away. F 23 2.5 years
11/8/2007
 4  Bipolar Disorder Chronic ringing in my ears. Short term memory loss. Periodic muscle twiching in my arms and legs, following nite time dosing. Taking 400mg at 7:00 PM daily. Seroquel is very effective as a antidepressant. Very good sleep inducer. Without the drug, I am unable sleep more than 3-4 hrs. per nite. In combination with Trileptal, moods are balanced. Compared to other drugs used for similar treatments, there are very few side effects. M 50 2.5 years
12/15/2004
 4  bipolar II, insomnia Initial side effects (stoned all day) were horrible, but have resolved. The first time I was started on seroquel, I stopped after a few days because I felt so hung over and stoned the next day. After several months, I agreed to try it again by starting out at a much lower dose. I'm now up to 200 mg at bedtime and sleep better than I ever have in my life (insomnia since infancy). Other than the initial negative side effects, my current dose isn't giving me problems; I have not gained weight on this drug and my lipids, blood sugars are fine. I'm currently titrating off zoloft and will be adding smaller doses of Seroquel during the day for anxiety. F 39 2.5 years
10/5/2006
 4  Bipolar Mania, Anxiety, Insomnia * Twitching of hands involuntarily (not too often); forgetfulness of basic things; mild weight gain; heart palpitations at night - occurred 1 hour consistently after taking medication Overall, this medicine has worked wonders to help my anxiety/mania - I used to panic at the slightest thing, now it takes a very strong trigger to do it. It helps tremendously in the 'staying asleep' aspect, however, going to sleep is a bit of a nighmare because my heart feels like an electric shock 1 hour after taking medication. Only last about 5 - 10 minutes. F 30 2.5 years
9/5/2009
 3  Bipolar I have gained 35 pounds in 2 1/2 years. Also, I find it difficult to fall asleep without it. Seroquel works really well for my bipolar disorder, but the weight gain has been horrible. F 30 2.5 years
6/16/2008
 2  Bipolar type 2 Extreme weight gain, restless legs and exhaustion. I grew up thinking that I had a horrible metabolism. I ate a fruit for breakfast, nothing for lunch and a small dinner. Since I stopped taking Seroquel, I have lost 30lb and eat like a normal person. I would also like to add that I am a very small person, so 30lb is quite significant. F 23 2.5 years
3/23/2009
 1  initially, a psychotic episode Combined with an antidepressant, Seroquel caused me symptoms similar to those of bipolar II. Also, weight gain (40 Kg in 2.5 years), profound sweating, constipation (had an operation for that), thyroid problems, elevated blood sugar and the beginnings of diabetes. I was on a combination of antypsychotic/antidepressant for more than 3 years. Specifically, on Seroquel/Seroxat for 2.5 years. I had other side effects in addition to those described above, and withdrawal problems, but those were most likely due to Seroxat. I quit all medication 2 years ago. Since then, my health - mental and physical - has improved substantially, though I'm still not as well as I used to be. M 30 2.5 years
5/6/2008
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 1  Bi-Polar, BP Disorder I went from a size 8 to a 16 in less than 6 months. My hair comes out in handsful. I am on 500 mg at night. Have been for almost 3 years. I cannot sleep without it. I still wake up every hour or so for at least 20 to 30 minutes. I work 12 hours a day on my feet moving constantly. When I did this before seroquel I could eat what I wanted and stay in good shape. This drug has just about shut my metabolism down. My mouth is so dry that if I can't drink immediately, my throat starts shutting off. My lips stick to my teeth. This is a nightmare. F 43 2.5 years
7/8/2009
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