PURINETHOL Reviews (MERCAPTOPURINE)

Average Rating: 3.5 (315 Ratings)

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PURINETHOL  (MERCAPTOPURINE):  This medication is used with other drugs to treat a certain type of cancer (acute lymphocytic leukemia). It is a chemotherapy drug that works by slowing or stopping the growth of cancer cells. Talk to the doctor about the risks and benefits of mercaptopurine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PURINETHOL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PURINETHOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  crohns none diagnosed at at 13.was taking prednisone did not help.had colectomy when i was 16.went in remission for 1 year before it came back.went back on prednisone again with no affect.started taking purinethol when i was 19 within a year i was feeling better,that was 11 years ago and been healthy since.i truly think purinethol saved my life. M 30 1 years
1/28/2006
 5  Crohns Little to no side effects- some very small liver spots on the inside of my hands, that's all. I have been on various levels of 6MP(purinethol) for almost 2 years. It is my miracle drug. I had symptoms for about two years before they took a biopsy and pin pointed my condition as Crohn's. Ever since I have had no major flare ups. F 19 2 years
1/27/2006
 2  Arthritis Fast Pulse the first time i took it i felt greate the secont and third it no longer worked.so they are going to up the dose and hopefully it will work F 22 8 days
12/21/2005
 2  Crohn's Disease Nausea, very tired I've been on this drug for about 3 months and just in the past week have been very nauseous. I'm not sure if I should continue with this medication, F 24 3 months
11/17/2005
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 2  Crohn's At first nothing...then after about 4 months, I started bruising for no reason, horrible flu like symptoms. I couldn't stand up for more that a few minutes before I started gagging and throwing up. Massive fatigue. Couldn't concentrate at work (and care for my 3 month old which is so frustrating). Anemia. Rappid heart rate. I also noticed red dots on my feet and itching, which I didn't attribute to the 6MP-but saw that many others had this same side effect. Brief History: Found out I had Crohn's when I was 6 months pg (June of 2005). Had two surgies during my pregnancy. Had peritonitis and removed my appendix, gall bladder and had a colon resection. Then they needed to restich my colon. Baby was born early but is doing great! Have been on prednisone (started at 80mg finally down to 2.5 mg!!), pentasa (250mg 16 pills a day), and 6-MP for 4 months. The bruising really concerned my dr so after 4 mos. he ordered me to go off the 6MP cold turkey. Today is my first day off it. I'm sure it will take longer to feel better. While I hate the side effects, I hope the Crohn's stays somewhat under control. I'm not sure the role 6MP was playing on my journey to remission F 26 4 months
11/11/2005
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 3  Chron's Gain of weight, stomach bloaded all the time and face, extremely tired, depression, irritable, low white cells, liver problems, feal like space out all the time in another world, no myself My doctor is in the process of doing some more test. if you feal very tired go see your doctor, he send me for blood test as result low white cell and liver problems. He than ask me if i was using injections...Ah i was so made. the only drugs im taking are the ones he prescibes. Will they please found a cure.. i cant take it anymore F 21 3 years
11/10/2005
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 3  UC headaches,nausea,fatiuge and join pain still having UC issues. does not seem to be working well for me. I want to try something else. F 38 10 months
11/7/2005
 4  crohns disease enlarged liver F 57 90 days
11/6/2005
 4  Crohn's Disease I am not sure but I think some of my short term memory loss and a few skin rashes and early aging spots can be attributed to purinethol Crohn's has been managable for the most part.. even though in 93 I had a major set back. I am taking 25 mg just a few times a week now to try and regain the short term memory loss and to see if a liver problem will subside. Other then that Doctor G in Scottsdale, Phoenix area got me on this back in 87, I been on it ever since.. No real complaints until the past couple years. if you need to email me just take out the nospam M 52 18 years
10/19/2005
 1  ulcerative colitis suffered total shut down of immune system..fluid in the lungs, enlarged spleen, and pancreitis. Only took the drug for about 11 weeks. M 19 11 days
10/12/2005
 2  Crohn's Terrible taste in my mouth, so bitter I sometimes can't get rid of it eating sweets. Doctor told me to stop taking Purinethol after 10 days. M 10 days
10/10/2005
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 2  Crohn's Terrible taste in my mouth, so bitter I sometimes can't get rid of it eating sweets. Doctor told me to stop taking Purinethol after 10 days. M 39 10 days
10/10/2005
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 1  crohn's nausea, abdominal pain, itching, general feeling of being sick, very tired I only took 6 mp for 3 days when the fatigue set in. Two days later the nausea and other side effects showed up. My doc wanted me to stay on the treatment but could not guarantee the symptoms would subside. I felt worse on the 6 mp than without it, so I quit after 8 days. I'm hoping the side effects wear off quickly. M 49 8 days
9/29/2005
 4  Crohn's disease none I've been on a combination of 6MP & Asacol for over 10 years. Previously I had been on Predinone when severely flared up. The 6MP & Asacol was a huge improvement. No real side effects to speak of and a healthy weight gain once it started helping. I still flare-up to some degree from time to time but have had success with the antibiotic Cipro which usually helps if I use it for a week or two. I believe 6MP has helped me treat my Crohn's along with careful diet and exercise. M 40 10 years
9/28/2005
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 3  Chron's Disease Itchy red bumps on my chest and weight gain I also take Asacol, 12 daily. Hard to say what's causing the rash, didn't have it until I started with the 6mp. F 37 6 days
9/27/2005
 3  Ulcerative Colitis Very tired, hair loss I have only been on it for 3 weeks, I feel I am getting more and more tired. I can live with the hair loss because I have soo much hair, however trying to function on a day to day basis is becoming too difficult. F 29 3 weeks
9/22/2005
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 5  Crohns disease I have had Crohns for 25 years and finally ended up having surgery. I'm now on 75 mg/day of purenithol. I have noticed some hair loss (but I'm 40 years old), and recently have been having lots of ringing in my ears. But, my Crohn's has been in near total remission. It's the best drug I've ever used for Crohns and I've tried just about all of them (not remicade). M 40 3 years
9/19/2005
 5  Crohn's Not sure. Fatigue could be from the 6MP, but could just as easily be from my not drinking enough water every day. Other than that, nothing. Had pretty bad Crohn's in my early-20s which Asacol and Pentasa failed to control. In January 2000 was completely obstructed and had laparoscopic ileocolic resection to fix. Was put on a mix of 6MP and Pentasa afterward, but had bad acne flareups, so stopped the Pentasa after about 3 months. Since then, 5+ years going strong and no symptoms of the Crohn's to speak of. Blood tests have all been normal, as have my colonoscopies. Been taking 50mg once daily the entire time. No known side-effects so far, and I do like to have a glass of wine or two with dinner a few nights a week. M 28 5 years
8/31/2005
 5  UC/Crohn's well, ive been on it nearly all my life, so i dont really remember (sorry). first off, ive had Crohn's since i was in 4th grade, so i guess ive had it for almost 11 years (19 yrs. old now). i argued that purinethol does nothing (for me), but ever since i was raised to 150mg its actually helped. i was up to over 80mg of prednisone (talk about side effects, and when you were in Jr. High at the time? jesus.) and the 100mg of purinethol did absolutely nothing. ever since the up in dosage, ive been off prednisone for years. prednisone destroyed the joints in my knees and hips (8 surgeries on my knees since 5th grade), and purinethol didnt help any of that but it did semi-save my soccer career. currently i play collegiate soccer and while in high school, undergoing constant terrible flair-ups before the raise in 6MP, i maintained a 3.2 GPA, defensive player of the year in soccer, and got an academic and athletic scholarship for college. anyone that says purinethol doesnt work can look at my situation. M 19 10 years
8/17/2005
 5  crohns I've had no side effects at all I've had crohns for over 30 years, been on Prendisone several times,with all of the side effects, had 2 surgeries & several bowel obstructions. Between the Remicade for about 3 years & the purinethol for about 5 years, I've been able to cut down on the other drugs I take for the Crohns. F 58 5 years
8/4/2005
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