PURINETHOL Reviews (MERCAPTOPURINE)

Average Rating: 3.5 (315 Ratings)

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PURINETHOL  (MERCAPTOPURINE):  This medication is used with other drugs to treat a certain type of cancer (acute lymphocytic leukemia). It is a chemotherapy drug that works by slowing or stopping the growth of cancer cells. Talk to the doctor about the risks and benefits of mercaptopurine, especially when used in children and young adults.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PURINETHOL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PURINETHOLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Crohn's Dry skin/rash on elbows, knees, and ankles Haven't been on 6-MP too long, a pharmacist friend found only liver effects. Nothing on interactions with alcohol, although alcohol is also an immunosuppresant, so that might be why alcohol should be avoided. Patients on low doses are probably not of great concern for this... also on Remicade, which 6-MP is supposed to replace after my next infusion. M 30 2 months
4/1/2003
 4  crohn's disease Slightly more irritable. It has helped me live a normal life. I can eat, and exercize, and not be in pain. I recommend it. F 33 6 months
3/31/2003
 5  Ulcerative Colitis Remission since '96, induced by Cyclosporin (off after 3 months). I believe Purinethol and Asacol are keeping me in Remission. M 37 7 days
3/22/2003
 5  Ulcerative Colitis increase in appetite I'm also on prednisone so that might be the cause of my increase in appetite. Was diagnosed with UC 1.5 years ago. Had a flare up since christmas and started purinethol (50mg) and prednisone at the same time 3 weeks ago. I'm only on pred for 4 more weeks. I'm doing great, but worried when I read about bad experiences other have had. Wondering about alcohol and meds as well. F 22 3 weeks
3/22/2003
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 4  Crohn's I have been irritable and a little depressed. I have no problems with Crohn's while taking this drug. I took it before and stopped taking it because I was so irritable. I had a flair up and had to start taking it again. It works on the Crohn's but I can hardly stand myself. F 32 4 months
3/18/2003
 2  Crohns Disease Nausea, Sick feeling after full meals, headaches, light headed feeling. Not sure if this has to do with the medicine yet, but these symptoms occured as soon as i started taking it. I was on pentasa for 4 months and it was working absolutely great for me, but a problem arose with my insurance, so my doctor sugested that I participate in a study of purinethol and azacotal (sp??) F 19 6 days
3/11/2003
 5  Ulcerative Colitis Possible dry skin. UC has really affected my life. At 5'10 M 18 4 months
3/7/2003
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 5  Ulcerative Colitis Possible dry skin. UC has really affected my life. At 5'10 M 18 4 months
3/7/2003
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 5  Ulcerative Colitis Possible dry skin. Couldnt tell with all the other drugs I'm taking. UC has really affected my life. At 5'10 M 18 4 months
3/7/2003
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 5  Ulcerative colitis NONE I have had Ulcerative Colitis since I was 18 and have developed Sacroilitis as well and 6mp/purinethol has helped the most out of all the drugs I have tried. I have not had any symptoms or problems from my colitis or sacroilitis since. F 35 1 years
2/19/2003
 5  UC None Have been back to normal ever since taking Purinethol! F 40 3 years
2/19/2003
 5  Chron's I have been taking 6-mp and cipro for 2 years and eight months with no side effects or flares. I also have had 3 remicade infussions which also helped. M 19 3 years
2/11/2003
 4  Ulcerative colitis Possible sensitve mouth. Nothing else so far but am taking prednisone and asacol also. Will know more when I'm off the prednisone. Combination of 3 blood transfusions, 12 day hospital stay, prednisone, asacol and purinethol and I have my life back again. F 42 24 days
1/31/2003
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 4  Crohn's Disease hair loss, depression, lack of energy, not happy at all any more I have been on 6-MP for over a year now, in combination with Remicade. I sincerley think that Remeicade has been a blessing to me. The unfortunate part is the cost involved. I can't say that I dis like 6-MP b/c I am not sure that is the root of my problems. My doctor, parents, and fience think it is best to stay on but I have a hutch that things might be better if I just stopped. Maybe I am just too dramatic but I was never this miserably before. Now I have to see a other doctors to prescribe other medications just to help me see the light. F 26 1 months
1/23/2003
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 3  Crohn's I haven't gotten my period in 34 days. I have been taking Purinethol for only two weeks and I have taken two pregnancy tests that are both negative. It has helped the crohn's a bit. F 40 15 days
1/21/2003
 3  UC Patchy areas of mild rash @ 100 mg / day After a huge flare up I was hospitalized for the first time to get the UC under control (originally diagnosed with UC 13 years ago). Had a Remicade infusion and started at 75 mg/day, huge improvement in 48 hours from the Remicade. First signs of symptoms reoccuring after 8 weeks, bumped Purenithol up to 100 mg/day and symptoms subsided after a few weeks. Pretty much in remission now but still have a bad day every few weeks. Just wish the precautions for this medication were a little more clear. Interaction with alcohol and effect on sperm quality (possible increase of birth defects??) aren't really consistent depending on the source. M 32 4 months
1/16/2003
 3  Ulcerative colitis F 14 9 months
1/9/2003
 5  ulcerative colitis hair loss (but may be due to sulfasalazine) This medication really was the ticket for me. I was first diagnosed with UC when I was 15 and went through basically all other treatment options. Pentasa, Asacol, Flagyl and the monster Prednisone(although it made me feel so good temporarily). These treatments all worked for about a month then my symptoms would come back. I missed a lot of school and a lot of my youth as I look back now. I try to keep informed and have found two really helpful websites: www.myucguide.com and www.gihealth.com Good luck to those who are in pain, I feel for you, and just know that things WILL get better with treatment and the best thing you can do is communicate with your doctor and especially with the people around you. M 20 4 years
1/8/2003
 1  Crohns wiped out my imune system . ended up in intesive care for 2 weeks M 38 3 weeks
12/22/2002
 3  UC can't pinpoint anything related specifically to this drug since I am on several others I have been on 6mp for about two months. I upped my dose to 100 mg daily about a month ago because I was being weaned off the prednisone and I was getting sick again. I have been off the pred for almost two weeks now and for the past week I have been having abdominal pain. The 6mp doesn't seem to be helping too much on its own...I am on asacol and flagyl...but it seems that the pred was really helping me. I am so glad I am off it because of the bad side effects, but now I am worried if the 6mp is going to be enough F 18 2 months
12/5/2002

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